Segura, Pedro Alejandro

Professeur, Faculté des sciences
FAC. SCIENCES Chimie

Coordonnées

Courriel


819-821-7922

Diplômes

(2013) Postdoctorat (Stage post-doctoral). McGill University.

(2011) Postdoctorat (Stage post-doctoral). Environment Canada.

(2009) Doctorat (Doctorat ès sciences). Université de Montréal.

(2004) Baccalauréat (Baccalauréat ès sciences). Université de Montréal.

Présentation

Sujets de recherche

Composition chimique, Dégradation, Molécules organiques et biomolécules, Polluants chimiques, Toxicologie.

Disciplines de recherche

Chimie, Eau et environnement.

Mots-clés

Analyse ultra-rapide, Chromatographie liquide, Contaminants émergents, Détection des bactéries pathogênes, Élucidation structurale, Environnement, Métabolomique, Salubrité des aliments, Spectrométrie de masse, Tests biologiques.

Intérêts de recherche

Je m'intéresse à la chimie analytique appliquée à l'environnement et à la salubrité des aliments. Mes axes principaux de recherche sont: 1) La détection des agents de contamination biologique ou chimique pouvant nuire les humains ou l'environnement. Cet axe vise à développer de nouvelles méthodes analytiques plus rapides et performantes permettant la détection des contaminants organiques et des bactéries pathogènes 2) Le devenir environnemental. Le but de cet axe est d'étudier les sous-produits des contaminants issus lors des processus de transformation d'origine anthropique ou naturel. 3) La toxicité des contaminants organiques. L'objectif de cet axe est de développer des tests biologiques plus sensibles basés sur la métabolomique et capables de détecter des effets subtils causés par les faibles concentrations des contaminants environnementaux et alimentaires.

Langues parlées et écrites

Anglais, Espagnol (castillan), Français

Prix et distinctions

  • (2013) Postdoctoral fellowship. Conseil de recherches en sciences naturelles et en génie (CRSNG). (Prix / Récompense).
  • (2013) Supplement for postdoctoral researchers receiving the NSERC postdoctoral fellowship. McGill University. (Prix / Récompense).
  • (2011) Postdoctoral scholar. McGill University. (Prix / Récompense).
  • (2011) Visiting fellowship. Conseil de recherches en sciences naturelles et en génie (CRSNG). (Prix / Récompense).
  • (2008) Doctoral research scholarship. Fonds de recherche du Québec - Nature et technologies (FRQNT). (Prix / Récompense).

Financement

Subvention. (En cours d’évaluation). Co-demandeur. Acquisition of a triple quadrupole mass spectrometer. (2019-2020).

Subvention. (Obtenu). Demandeur principal. Faculty financial support for research and scholarships (2017-2019). (2017-2019).

Subvention. (Terminé). Co-demandeur. Automatic solid-phase extraction system for the study of small organic molecules in environmental and biological samples. (2018-2019).

Subvention. (Terminé). Demandeur principal. Faculty financial support for research and scholarships (2014-2016). (2014-2018).

Subvention. (Terminé). Demandeur principal. Faculty financial support for research and scholarships (2016-2018). (2016-2018).

Subvention. (Obtenu). Demandeur principal. Removal of municipal wastewater effluent toxicity and formation of transformation products of trace organic contaminants after electrochemical oxidation treatment. (2018).

Bourse d’études. (Obtenu). Demandeur principal. Wage Subsidy for Environmental Students. (2018).

Subvention. (Obtenu). Demandeur principal. New approaches to improve thermal desorption of small organic molecules by LDTD-MS/MS. (2018).

Subvention. (Obtenu). Co-demandeur. High throughput extraction platform for the analysis of organic compounds in solid and semisolid matrices. (2017-2018).

Subvention. (Terminé). Demandeur principal. Faculty financial support for research and scholarships (2015-2017). (2015-2017).

Subvention. (Terminé). Demandeur principal. Wage Subsidy from Emploi Québec. (2016-2017).

Subvention. (Terminé). Demandeur principal. Ultrafast method for the screening of organic microcontaminants in wastewaters and surface waters. (2017).

Subvention. (Terminé). Demandeur principal. Towards a Greener Semiconductor Industry Symposium. (2016).

Subvention. (Terminé). Demandeur principal. Towards recovery of used water generated by a semiconductor surface cleaning process. (2016).

Publications

Articles de revue

  • Lecours M.-A., Eysseric E., Yargeau V., Lessard J., Brisard G. M., Segura P. A. (2018). Electrochemistry-High Resolution Mass Spectrometry to Study Oxidation Products of Trimethoprim. Enviroments, 5(1), 1-18. (Article publié).
  • da Silva Junior C. A., Segura P. A. (2018). Identification of Dyes in Pen Ink by High Resolution Mass Spectrometry: A Laboratory Experiment. Journal of Laboratory Chemical Education, 5(5), 108-115. (Article accepté).
  • Psutka J., Dion-Fortier A., Dieckmann T., Campbell J. L., Segura P. A., Hopkins W. S. (2018). Identifying Fenton-Reacted Trimethoprim Transformation Products Using Differential Mobility Spectrometry. Analytical Chemistry, 90(8), 5352-5357. (Article publié).
  • Segura P. A., Racine M*, Gravel A., Eysseric E.*, Grégoire A-M.*, Rawach D., Teysseire F.-X. (2018). Impact ofmethod parameters on the performance of suspect screening for theidentification of trace organic contaminants in surface waters. Canadian Journal of Chemistry, (Révisions requises).
  • Segura P. A., Barry K., Eysseric E., Gallagher-Duval S., Venne P., Bélanger G. (2018). Method for the Routine Determination of Accurate Masses by Triple Quadrupole Mass Spectrometry. Methods and Protocols, 1(9), 1-10. (Article publié).
  • Eysseric E., Beaudry F., Gagnon C., Segura P. A. (2018). Novel workflow for non-targeted screening of common trace organic contaminants in surface waters. Analytical Chemistry, (Article soumis).
  • Dion-Fortier A., Gravel A.*, Guérette C., Chevillot F., Blais S., Auger S., Picard P., Segura P. A. (2018). Signal enhancement in laser-diode thermaldesorption-triple quadrupole mass spectrometry analysis using microwell surfacecoatings. Journal of Mass Spectrometry, (Article soumis).
  • Eysseric E, Barry K, Beaudry F, Houde M, Gagnon C, Segura PA. (2017). Application of spectral accuracy to improve the identification of organic compounds in environmental analysis. Analytical Chemistry, 89(18), 9805-9813. (Article publié).
  • Eysseric E, Bellerose X, Lavoie J-M, Segura PA. (2017). Effect of steam treatments on the availability of various families of secondary metabolites extracted from green sweet sorghum. Industrial Crops and Products, 104, 120-128. (Article publié).
  • Poirier-Larabie S, Segura PA, Gagnon C. (2016). Degradation of the pharmaceuticals diclofenac and sulfamethoxazole and their transformation products under controlled environmental conditions. Science of the Total Environment, 557, 257-267. (Article publié).
  • Rodayan A, Afana S, Segura PA, Sultana T, Metcalfe CD, Yargeau V. (2016). Linking drugs of abuse in wastewater to contamination of surface and drinking water. Environmental Toxicology and Pollution, 35(4), 843–849. (Article publié).
  • Eysseric E, Bellerose X, Lavoie JM, Segura PA. (2016). Post-column hydrogen–deuterium exchange technique to assist in the identification of small organic molecules by mass spectrometry. Canadian Journal of Chemistry, 94(9), 781-787. (Article publié).
  • Venne P, Yargeau V, Segura PA. (2016). Quantification of ecdysteroids and retinoic acids in whole daphnids by liquid chromatography-triple quadrupole mass spectrometry. Journal of Chromatography A, 1438, 57-64. (Article publié).
  • Segura PA, El Saadi K, Clair A, Lecours M-A, Yargeau V. (2015). Application of XCMS online and toxicity bioassays to the study of transformation products of levofloxacin. Water Science and Technology, 72(9), 1578-1587. (Article publié).
  • Segura PA, Takada H, Correa JA, El Saadi K, Koike T, Onwona-Agyeman S, Ofosu-Anim J, Sabi EB, Wasonga OV, Mghalu JM, dos Santos Junior AM, Newman B, Weerts S, Yargeau V. (2015). Global occurrence of anti-infectives in surface waters: impact of income inequality between countries. Environment International, 80, 89-97. (Article publié).
  • Rabii FW , Segura PA , Fayad PB , Sauvé S. (2014). Determination of six chemotherapeutic agents in municipal wastewater using online solid-phase extraction coupled to liquid chromatography-tandem mass spectrometry. The Science of the Total Environment, 487, 792-800. (Article publié).
  • Rodayan A, Segura PA, Yargeau V. (2014). Ozonation of wastewater: Removal and transformation products of drugs of abuse. The Science of the Total Environment, 487, 763-70. (Article publié).
  • Segura PA , Kaplan P* , Yargeau V. (2013). Identification and structural elucidation of ozonation transformation products of estrone. Chemistry Central Journal, 7(74), 1-11. (Article publié).
  • Segura PA, Gagnon C, Yargeau, V. (2013). On the application of high-resolution mass spectrometry to environmental analysis. International Journal of Environmental Pollution and Remediation, 1(1), 85-92. (Article publié).
  • Segura PA, Kaplan P*, Erythropel HC, Yargeau V. (2012). Comparative rapid toxicity screening of commercial and potential "green" plasticizers using bioluminescent bacteria. Industrial and Engineering Chemical Research, 51(35), 11555-11560. (Article publié).
  • Lajeunesse A , Segura PA , Gélinas M , Hudon C , Thomas K , Quilliam MA , Gagnon C. (2012). Detection and confirmation of saxitoxin analogues in freshwater benthic Lyngbya wollei algae collected in the St. Lawrence River (Canada) by liquid chromatography-tandem mass spectrometry. Journal of chromatography, A, 1219(6 Jan 2012), 93-103. (Article publié).
  • Garcia-Ac A , Segura PA , Viglino L , Gagnon C , Sauvé S. (2011). Comparison of APPI, APCI and ESI for the LC-MS/MS analysis of bezafibrate, cyclophosphamide, enalapril, methotrexate and orlistat in municipal wastewater. Journal of Mass Spectrometry, 46(4), 383-390. (Article publié).
  • Segura PA , MacLeod SL , Lemoine P* , Sauvé S , Gagnon C. (2011). Quantification of carbamazepine and atrazine and screening of suspect organic contaminants in surface and drinking waters. Chemosphere, 84(8), 1085-1094. (Article publié).
  • Segura PA , Tremblay P , Picard P , Gagnon C , Sauvé S. (2010). High-throughput quantitation of seven sulfonamide residues in dairy milk using laser diode thermal desorption-negative mode atmospheric pressure chemical ionization tandem mass spectrometry. Journal of Agricultural and Food Chemistry, 58(3), 1442-1446. (Article publié).
  • Segura PA, Gagnon C, Sauvé S. (2009). Application of turbulent flow chromatography load columns to the on-line analysis of anti-infectives in wastewaters. Chromatographia, 70(July (1/2)), 239-245. (Article publié).
  • Garcia-Ac A , Segura PA , Gagnon C , Sauvé S. (2009). Determination of bezafibrate, methotrexate, cyclophosphamide, orlistat and enalapril in waste and surface waters using on-line solid-phase extraction liquid chromatography coupled to polarity-switching electrospray tandem mass spectrometry. Journal of Environmental Monitoring, 11(4), 830-838. (Article publié).
  • Garcia-Ac A , Segura PA , Viglino L , Fürtös A , Gagnon C , Prévost M , Sauvé S. (2009). On-line solid-phase extraction of large-volume injections coupled to liquid chromatography-tandem mass spectrometry for the quantitation and confirmation of 14 selected trace organic contaminants in drinking and surface water. Journal of Chromatography, A, 1216(48), 8518-8527. (Article publié).
  • Segura PA , François M , Gagnon C , Sauvé S. (2009). Review of the occurrence of anti-infectives in contaminated wastewaters and natural and drinking waters. Environmental health perspectives, 117(5), 675-684. (Article publié).
  • Segura PA , Gagnon C , Sauvé S. (2007). A fully automated on-line preconcentration and liquid chromatography-tandem mass spectrometry method for the analysis of anti-infectives in wastewaters. Analytica Chimica Acta, 604(2), 147-157. (Article publié).
  • Segura PA , García-Ac A , Lajeunesse A , Ghosh D , Gagnon C , Sauvé S. (2007). Determination of six anti-infectives in wastewater using tandem solid-phase extraction and liquid chromatography-tandem mass spectrometry. Journal of Environmental Monitoring, 9(4), 307-313. (Article publié).

Livres

  • Segura PA. (2010). Agents anti-infectieux dans les eaux: Présence dans l'environnement et développement de techniques analytiques pour leur détermination Éditions universitaires européennes. (Article publié).

Rapports

  • Segura PA, Gagnon C. (2010). Assessment on the chronic exposure effects to anti-infectives in surface and drinking waters. Environment Canada. 9 p.

Articles de conférence

  • Boucher V., Lemoine P., Vermette J.-F., Segura P. A. (2018). Elimination of pharmaceuticals in wastewaters by wet-air oxidation. Conference Program, 64. (Article publié).
  • Dion-Fortier A., Chevillot F., Blais S., Picard P., Auger S, Segura P. A. (2018). New plate coatings for LDTD-MS/MS analysis. Online Conference Proceedings, 291633. (Article publié).
  • Lahens L., Dion-Fortier A., Cabana H., Segura P. A. (2018). Preliminary study of the occurrence of trace organic contaminants in Canadian lakes. Conference Program, 51. (Article publié).
  • Lahens L., Dion-Fortier A., Cabana H., Segura P. A. (2018). Preliminary study of the occurrence of trace organic contaminants in Canadian lakes. Conference Program, 69. (Article publié).
  • Psutka J., Dion-Fortier A., Segura P. A., Dieckmann T., Campbell J. L., Hopkins W. S. (2018). Separation and Identification of Transformation Products of Trimethoprim Using Differential Mobility Spectrometry. Conference Program, 17. (Article publié).
  • Dion-Fortier A., Picard P., Auger S, Segura P. A. (2018). Ultra-fast screening ofmicropollutants in surface water by LDTD-MS/MS. Conference Program, 51. (Article publié).
  • Dion-Fortier A., Picard P., Auger S, Segura P. A. (2018). Ultra-fast screening of micropollutants in surface water by LDTD-MS/MS. Online Conference Proceedings, 291572. (Article publié).
  • Dion-Fortier A., Picard P., Auger S, Segura P. A. (2018). Ultra-fast screening ofmicropollutants in surface water by LDTD-MS/MS. Conference Program, 61. (Article publié).
  • Racine M., Segura P. A. (2016). Analysis of emerging contaminants in the St‐François river using a suspect screening method. Conference Program, 13. (Article publié).
  • Da Silva C. A., Segura P. A. (2016). Application of matrix assisted laser desorption ionization quadrupole time-of-flight (MALDI-QqTOF)mass spectrometry to the analysis of ballpoint pen inks on paper. Conference Program, (Article publié).
  • Poirier-Larabie S., Segura P. A., Gagnon C. (2016). Degradation of two pharmaceuticals, diclofenac and sulfamethoxazole and their degradation products under various controlled environmental conditions. Conference Program, 47. (Article publié).
  • Eysseric E., Barry K., Houde M., Gagnon C., Segura P. A. (2016). Improved certitude in the determination ofmolecular formulas for environmental analysis using spectral accuracy. Conference Program, 13. (Article publié).
  • Eysseric E, Bellerose X, Lavoie J-M. Segura PA. (2016). Post-column hydrogen-deuterium exchange method for the identification of organic compounds. Online Conference Proceedings, 278655. (Article publié).
  • Da Silva Junior C. A., Segura P. A. (2015). Application of matrix assisted laser desorption ionization quadrupole time-of-flight (MALDI-QqTOF)mass spectrometry to the analysis of ballpoint pen inks on paper. Conference Program, (Article publié).
  • Venne P*, Yargeau V, Segura PA. (2015). Daphnia magna Method Optimization for the Separation and Quantification of Key Metabolites in Tissues. Conference Agenda, 20. (Article publié).
  • Lecours M-A, Brisard G, Segura PA. (2015). Development of electrochemical methods capable of mimicking oxidative degradation pathway of model pharmaceuticals. Conference Proceedings, 269195. (Article publié).
  • Desrochers F.-X.*, Segura P. A., Lavoie J.-M. (2015). Identification of Secondary Metabolites in Switchgrass (Panicum virgatum) by Mass Spectrometry. Conference Program, 01529. (Article publié).
  • Venne P, Yargeau V, Segura PA. (2015). Method Optimization for the Separation and Quantification of Key Metabolites in Daphnia magna tissues. Online Conference Proceedings, 258248. (Article publié).
  • Fauteux M., Segura, P. A., Gaudreau L. (2015). Study of cellular disturbances caused by contaminants present in Québec's drinking water (translated from original title in French). Conference Program, 42. (Article publié).
  • Venne P*, Yargeau V, Segura PA. (2014). Bioassay for the evaluation of the impact of trace xenobiotics in the aquatic environment (translation of the original title in French). Conference Program, 48. (Article publié).
  • Lecours MA*, Clair A*, Saadi K*, Yargeau V, Segura PA. (2014). Identification and characterisation of ozonation transformation products of azithromycin by high resolution mass spectrometry (translation of the original title in French). Conference program, 48. (Article publié).
  • Segura PA, Rodayan A, Kaplan P*, Saadi K*, Benoit R, Yargeau V. (2013). Identification and structural elucidation of ozonation transformation products of emerging contaminants. Conference Proceedings, 235219. (Article publié).
  • Yargeau V, Segura PA, Kaplan P*. (2013). Nature and estrogenic activity of ozonation transformation products of estrone. Programme and abstract book, P118. (Article publié).
  • Segura PA, Kaplan P*, Erythropel HC, Cooper DG, Yargeau V. (2012). Evaluation of the acute toxicity of commercial and potential green plasticizers using bioluminescent bacteria (translation of the original title in French). Conference Program, 53. (Article publié).
  • Rabii F*, Fayad PB, Segura PA, Sauvé S. (2012). New method for the detection of chemotherapy agents in wastewaters using online SPE-LC-MS/MS (translation of the original title in French). Conference Program, 49. (Article publié).
  • Segura PA, Gagnon C, Yargeau V. (2012). On the Application of High-Resolution Mass Spectrometry to Environmental Analysis. Conference Proceedings, Paper 161. (Article publié).
  • Segura PA, Kaplan P*, Erythropel HC, Cooper DG, Yargeau V. (2012). Rapid acute toxicity screening of commercial and potential green plasticizers using bioluminescent bacteria. Conference Abstract Book, 187. (Article publié).
  • Segura PA, Gagnon C, Sauvé S. (2008). Comparison of turbulent-flow chromatography and conventional reversed-phase liquid chromatography for the on-line preconcentration of anti-infectives in wastewaters. Conference Program, S90. (Article publié).
  • Fayad PB, Segura PA, Picard P, Prévost M, Sauvé S. (2008). Novel determination method of anti-infectives and estrogenic endocrine disruptors in wastewater and drinking water using LDTD-APCI-MS/MS. Conference Program, 590. (Article publié).
  • Segura PA, Tremblay P, Picard P, Fortier S, Gagnon L, Gagnon C, Sauvé S. (2008). Ultra fast quantifications of sulfamerazine, sulfamethoxazole, sulfadimethoxine and sulfamethazine residues in milk using LDTD-APCI-MS/MS. Conference Program, S88. (Article publié).

Autres contributions

Cours enseignés

  • Sécurité. CHM 319. (2017-01-03). Université de Sherbrooke. Canada.
  • Structure et réactivité de la matière. CHM101. (2015-09-01). Université de Sherbrooke. Canada.
  • Analyse instrumentale. CAN 400. (2014-09-02). Université de Sherbrooke. Canada.
  • Techniques de séparation. CAN 306. (2014-01-10). Université de Sherbrooke. Canada.

Gestion d'évènements

  • Symposium Co-chair. (2018). 32nd Eastern Canadian Symposium. (Conférence).
  • Symposium Chair. (2016). Towards a greener semiconductor industry. (Atelier).
  • President of the organizing committee. (2015). 19th Annual meeting of the Chapitre Saint-Laurent. (Conférence).
  • Session chair (Instrumentation and analytical development). (2015). 19th Annual meeting of the Saint-Lawrence Chapter. (Conférence).
  • Session Chair (New techniques and methods of analysis). (2014). 18th Annual meeting of the Chapitre Saint-Laurent. (Conférence).
  • Member of the organizing committee. (2014). 18th Annual meeting of the Chapitre Saint-Laurent. (Conférence).
  • Member of the organizing committee. (2013). 17th Annual meeting of the Chapitre Saint-Laurent. (Conférence).
  • Member of the organizing committee. (2012). 16th Annual meeting of the Chapitre Saint-Laurent. (Conférence).

Activités de collaboration internationale

  • Project leader. (2013-2014). Canada.

Présentations

  • (2018). New techniques of identification of organic contaminants in the aquatic environment (translated from original title in French). Conference at the Department of Chemistry of Université Laval. Québec, Canada.
  • (2018). New techniques of identification of small organic molecules by mass spectrometry : applications and perspectives (translated from original title in french). 86e Congrès de l’ACFAS. Saguenay, Canada.
  • (2018). Spectral accuracy: a new tool for the identification of small organic molecules. Mass Spectrometry Workshop. Sainte-Anne-de-Bellevue, Canada.
  • (2017). Organic contaminants in the Aquatic Environment: Novel Identification Strategies and Potential Human Impacts. 7th Mass Spectrometry Symposium. Sherbrooke, Canada.
  • (2016). On the Application of Electrochemistry-Mass Spectrometry to Study the Biotransformation of UV Blockers in the Environment. 64th ASMS Conference on Mass Spectrometry and Allied Topics. San Antonio, États-Unis.
  • (2016). Towards a mass-spectrometry based metabolomic toxicity bioassay using Daphnia magna. Toronto Mass Spec Group Meeting. Toronto, Canada.
  • (2015). Anti-infectives in the surface waters of lower income countries. 19th Annual Meeting of the Chapitre St-Laurent. Sherbrooke, Canada.
  • (2014). New perspectives for the study of organic contaminants in the environment. 1st Workshop of the Network of Universities of the Province of Buenos Aires and the Universities and Research Centres of Quebec. Mar del Plata, Argentine.
  • (2014). Study of transformation products of emerging contaminants : challenges and solutions (translation of the original title in French). Conferences of the Groupe de Recherche sur l'eau of Université de Sherbrooke (GREAUS). Sherbrooke, Canada.
  • (2013). Analytical chemistry applied to environmental microbiology: new perspectives (translation of the original title in French). Conference Armand-Frappier at the Centre INRS–Institut Armand-Frappier. Laval, Canada.
  • (2013). Global occurrence of anti-infectives in environmental waters: impact of income inequality between countries. 17th Annual Meeting of the SETAC-Saint Lawrence Chapter. Montréal, Canada.
  • (2013). Identification and structural elucidation of ozonation transformation products of emerging contamiants(translation of the original title in French). 17th Annual Meeting of the SETAC-Saint Lawrence Chapter. Montréal, Canada.
  • (2013). My profession: scientific research in chemistry (translation of the original title in French). Presentation to the students of secondary 3 of Saint-Henri school. Montréal, Canada.
  • (2012). Application of modern techniques of mass spectrometry and bioassays to the study of emerging contaminants (translation of the original title in French). Conference for the Department of Chemistry of Université de Sherbrooke. Sherbrooke, Canada.
  • (2012). Estrogenic activity and transformation products of endocrine disrupting compounds due to ozonation with sub-optimal doses. 16th Annual Meeting of the SETAC-Saint Lawrence Chapter. Québec, Canada.
  • (2012). High-resolution mass spectrometry: the future of environmental analysis. Perkin-Elmer Inspiring Innovation North American Tour Workshop. Montréal, Canada.
  • (2012). On the application of high-resolution mass spectrometry to environmental analysis. 2nd International Conference on Environmental Pollution and Remediation. Montréal, Canada.
  • (2012). Potential of high-resolution mass spectrometry to identify and analyze contaminants of emerging concern and their transformation products (translation of the original title in French). 16th Annual Meeting of the SETAC-Saint Lawrence Chapter. Québec, Canada.
  • (2011). Pharmaceutical compounds: transformation products and residual toxicity / Les composés pharmaceutiques : produits de transformation et toxicité résiduelle. 15th Annual Meeting of the SETAC-Saint Lawrence Chapter. Montréal, Canada.
  • (2010). New methods for the detection of traces of antibiotics and other organic contaminants in environmental waters (translation of the original title in French). 14th Annual Meeting of the SETAC-Saint Lawrence Chapter. Québec, Canada.

Les informations disponibles dans la base de données Expertus sont tirées du CV commun canadien.