Sameh Geha
Directeur de département, Faculté de médecine et des sciences de la santé
FMSS Département de pathologie
Présentation
Sujets, disciplines ou intérêts de recherche
cancers colon, cancer du sein, Hybridation in situ chromogénique HER2, histopathologie, Immunohistochimie
Qualifications
- Directeur de programme de résidence. Pathologie. Université de Sherbrooke. Sherbrooke, Quebec, Canada. (2011-2018).
Expériences académiques
- Directeur de département/Chef de service hospitalier de pathologie. (2018-2026). Université de Sherbrooke. Sherbrooke, Quebec, Canada.
Publications
Articles
- Charles-Davyd Rioux, Sungmi Jung, Claude Saint-Jean, Martin Borduas, Sameh Geha. (2025). Plexiform fibromyxoma located in the distal small bowel: A case report. Canadian Journal of Medical Specialties. DOI
- Ghanaatgar Kasbi S, Savard M, Couture F, Dubuc C, Dumulon-Perreault V, Nepveu-Traversy ME, Ait-Mohand S, Sabbagh R, Geha S, Guérin B, Dory Y, Gobeil F. (2025). Theranostic Potential of a New <sup>64</sup>Cu-Labeled NOTA-R954 Peptide Conjugate for Kinin B1R Expressing Prostate Cancer. Pharmaceutics. DOI
- Plante C, Mohamad T, Hewa Bostanthirige D, Renaud M, Sidhu H, ElChoueiry M, Vatasescu JS, Poirier M, Geha S, Brosseau JP. (2024). Revisiting the NPcis mouse model: A new tool to model plexiform neurofibroma. PloS one. DOI
- Leon L, Marrero Cofino G, Delannoy A, Placet M, Geha S, Verdú E, Fortier L, Menendez A, Saucier C. (2023). A194 IMPACT OF SUPPRESSOR OF CYTOKINE SIGNALING 1 (SOCS1) EXPRESSION IN INTESTINAL EPITHELIAL CELLS ON THE GUT MICROBIOTA. Journal of the Canadian Association of Gastroenterology.
- Rhéaume K, Chen Z, Wang Y, Plante C, Hewa Bostanthirige D, Lévesque M, Geha S, Le LQ, Brosseau JP. (2023). Whole Central and Peripheral Nervous System Mice Dissection. Journal of visualized experiments : JoVE. DOI
- Milot MC, Bélissant-Benesty O, Dumulon-Perreault V, Ait-Mohand S, Geha S, Richard PO, Rousseau É, Guérin B. (2023). Theranostic <sup>64</sup>Cu-DOTHA<sub>2</sub>-PSMA allows low toxicity radioligand therapy in mice prostate cancer model. Frontiers in oncology. DOI
- Echelard P, Roy SF, Trinh VQ, Garant MP, Collin Y, Nguyen BN, Geha S. (2021). Age, operation time and surgical approach can be used to detect incidental gallbladder carcinoma in cholecystectomy specimens from low-incidence settings. Histopathology. DOI
- Sohail M, Shkreta L, Toutant J, Rabea S, Babeu JP, Huard C, Coulombe-Huntington J, Delannoy A, Placet M, Geha S, Gendron FP, Boudreau F, Tyers M, Chabot B. (2021). A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells. NAR cancer. DOI
- Samson N, Nadeau C, Cantin D, Farkouh R, Robinson M, Elnazir P, Geha S, Bussières M, Praud JP. (2021). Respiratory activity of the cricopharyngeus muscle in the neonatal period. Respiratory physiology & neurobiology. DOI
- Placet M, Molle CM, Arguin G, Geha S, Gendron FP. (2021). The expression of P2Y<sub>6</sub> receptor promotes the quality of mucus in colitic mice. The FEBS journal. DOI
- Maxime Gagnon, Martin Savard, Jean-François Jacques, Ghassan Bkaily, Sameh Geha, Xavier Roucou, Fernand Gobeil. (2021). Potentiation of B2 receptor signaling by AltB2R, a newly identified alternative protein encoded in the human bradykinin B2 receptor gene. Journal of Biological Chemistry. DOI
- Michaud A, Jia WL, Djeddi D, Samson N, Nadeau C, Geha S, Praud JP. (2020). Effects of upper airway obstruction or hypoxia on gastroesophageal reflux in newborn lambs. Pediatric research. DOI
- Constanzo J, Midavaine É, Fouquet J, Lepage M, Descoteaux M, Kirby K, Tremblay L, Masson-Côté L, Geha S, Longpré JM, Paquette B, Sarret P. (2020). Brain irradiation leads to persistent neuroinflammation and long-term neurocognitive dysfunction in a region-specific manner. Progress in neuro-psychopharmacology & biological psychiatry. DOI
- Dubuc C, Savard M, Bovenzi V, Lessard A, Côté J, Neugebauer W, Geha S, Chemtob S, Gobeil F. (2018). Antitumor activity of cell-penetrant kinin B1 receptor antagonists in human triple-negative breast cancer cells. Journal of cellular physiology. DOI
- Babeu JP, Jones C, Geha S, Carrier JC, Boudreau F. (2018). P1 promoter-driven HNF4α isoforms are specifically repressed by β-catenin signaling in colorectal cancer cells. Journal of cell science. DOI
- Chauvin A, Wang CS, Geha S, Garde-Granger P, Mathieu AA, Lacasse V, Boisvert FM. (2018). The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature. Clinical proteomics. DOI
- Chauvin A, Mathieu A, Lacasse V, Wang C, Geha S, Garde-Granger P, Boisvert F. (2018). A256 DETERMINATION OF PROTEOMIC SIGNATURE OF RESPONSE TO NEOADJUVANT RADIO-CHEMOTHERAPY IN COLORECTAL CANCER PATIENTS. Journal of the Canadian Association of Gastroenterology.
- Constanzo J, Dumont M, Lebel R, Tremblay L, Whittingstall K, Masson-Côté L, Geha S, Sarret P, Lepage M, Paquette B, Descoteaux M. (2018). Diffusion MRI monitoring of specific structures in the irradiated rat brain. Magnetic resonance in medicine. DOI
- Placet M, Arguin G, Molle CM, Babeu JP, Jones C, Carrier JC, Robaye B, Geha S, Boudreau F, Gendron FP. (2018). The G protein-coupled P2Y₆ receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis. Biochimica et biophysica acta. Molecular basis of disease. DOI
- Dubuc C, Savard M, Bovenzi V, Lessard A, Fortier A, Côté J, Neugebauer W, Rizzolio F, Geha S, Giordano A, Chemtob S, Gobeil F. (2018). Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer. Oncotarget. DOI
- Gu L, Comeau E, Geha S. (2017). [Even a cholecystitis can surprise you]. Annales de pathologie. DOI
- Chevrier M, Bobbala D, Villalobos-Hernandez A, Khan MG, Ramanathan S, Saucier C, Ferbeyre G, Geha S, Ilangumaran S. (2017). Expression of SOCS1 and the downstream targets of its putative tumor suppressor functions in prostate cancer. BMC cancer. DOI
- Bouchard G, Therriault H, Geha S, Bujold R, Saucier C, Paquette B. (2017). Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model. British journal of cancer. DOI
- Constanzo J, Masson-Côté L, Tremblay L, Fouquet JP, Sarret P, Geha S, Whittingstall K, Paquette B, Lepage M. (2016). Understanding the continuum of radionecrosis and vascular disorders in the brain following gamma knife irradiation: An MRI study. Magnetic resonance in medicine. DOI
- Bouchard G, Therriault H, Geha S, Bérubé-Lauzière Y, Bujold R, Saucier C, Paquette B. (2016). Stimulation of triple negative breast cancer cell migration and metastases formation is prevented by chloroquine in a pre-irradiated mouse model. BMC cancer. DOI
- Del Castillo M, Chibon F, Arnould L, Croce S, Ribeiro A, Perot G, Hostein I, Geha S, Bozon C, Garnier A, Lae M, Vincent-Salomon A, MacGrogan G. (2015). Secretory Breast Carcinoma: A Histopathologic and Genomic Spectrum Characterized by a Joint Specific ETV6-NTRK3 Gene Fusion. The American journal of surgical pathology. DOI
- Ducharne-Asuaje E, Dorion D, Lamarre L, Coindre JM, Geha S. (2015). Primary High-Grade Poorly Differentiated Angiosarcoma of an Intra-parotid Lymph Node. Head and neck pathology. DOI
- Akhdar A, Bronsard M, Lemieux R, Geha S. (2011). [HER-2 oncogene amplification assessment in invasive breast cancer by dual-color in situ hybridization (dc-CISH): a comparative study with fluorescent in situ hybridization (FISH)]. Annales de pathologie. DOI
- Pallud J, Varlet P, Devaux B, Geha S, Badoual M, Deroulers C, Page P, Dezamis E, Daumas-Duport C, Roux FX. (2010). Diffuse low-grade oligodendrogliomas extend beyond MRI-defined abnormalities. Neurology. DOI
- Geha S. (2009). [Arteriolar cholesterol emboli in the gallbladder]. Annales de pathologie. DOI
- Geha S, Pallud J, Junier MP, Devaux B, Leonard N, Chassoux F, Chneiweiss H, Daumas-Duport C, Varlet P. (2009). NG2+/Olig2+ cells are the major cycle-related cell population of the adult human normal brain. Brain pathology (Zurich, Switzerland). DOI
- Zoubir M, Mathieu MC, Mazouni C, Liedtke C, Corley L, Geha S, Bouaziz J, Spielmann M, Drusche F, Symmans WF, Delaloge S, Andre F. (2008). Modulation of ER phosphorylation on serine 118 by endocrine therapy: a new surrogate marker for efficacy. Annals of oncology : official journal of the European Society for Medical Oncology. DOI
- Checrallah A, Geha S, Rizk T, Koussa S. (2005). [Multiple sclerosis mimicking brain tumor: an unusual presentation]. Le Journal medical libanais. The Lebanese medical journal.
