Aller au contenu

Ryan Gosselin

Professeur, Faculté de génie
FAC. GÉNIE Chimique et biotechnologique


Sujet de recherche

Chemical Processes, Data mining, Imagery, Mechanical and Physical Processes, Quality Control

Disciplines de recherche

Chemical Engineering


Chemometrics, Hyperspectral Imaging, Image Analysis, Multivariate Data, Process Analytical Tech, Process Monitoring, Quality by Design, Quality Control, Spectroscopy

Langues parlées et écrites

Anglais, Français, Espagnol (castillan)


(2010). On-line Quality Control in Processing Using Hyperspectral Imaging (Doctorate, Chemical Engineering). Université Laval.

(2005). Injection of Post-Consumption Foamed Wood/Plastic Composites (Injection de Mousses Composites Bois/Plastique d'Origine Post-Consommation) (Master's Thesis, Chemical Engineering - Masters). Université Laval.

(2003). (Bachelor's, Chemical Engineering). Université Laval.

Prix et distinctions

  • (2014) Prix Bazinet. Université de Sherbrooke. (Distinction).


Articles de revue

  • Palmero-Durao P. Abatzoglou N., Guay J.M. and Gosselin R. (2015). Monitoringthe Concentration of Flowing Pharmaceutical Powders in a Tableting Feed Frame. Pharmaceutical Development and Technology (Accepted).
  • Chaib O, Abatzoglou N. and Gosselin R. (2015). Applicationof NIR Spectroscopy in Linking Velocity Profiles of a Binary Granular System. European Pharmaceutical Review (20), 7-12. (Published).
  • Ketsia Yekpe, Nicolas Abatzoglou, Bernard Bataille, Ryan Gosselin, Tahmer Sharkawi, Jean-Sébastien Simard, Antoine Cournoyer. (2015). Predicting the dissolution behavior of pharmaceutical tablets with NIRchemical imaging. International Journal of Pharmaceutics (486), 242–251. (Published).
  • Nicolas Abatzoglou, Eddy Castellanos Gil, Ryan Gosselin. (2014). Influence of Hopper Geometry on Radial and Axial ConcentrationProfiles in Flows of Segregated and Homogenized Granular Mixtures. Powder Technology (262), 42-50. (Published).
  • Gosselin R., Abatzoglou N., Quinn P., Salvas J. and Simard J.S. (2014). Novel methodologiesfor determining the mineral content of complex multivitamin tablets. European Pharmaceutical Review 19 (4), 62-68. (Published).
  • Abatzoglou N., Gosselin R., Inam, M.A. (2013). Rheological Characterization and Empirical Modelling of Non-AcqueousNano-Suspensions of Iron Carbide Produced by Plasma Spray. Chemical Engineering Journal 92 (1), 68-74. (Published).
  • Guay J.M., Lapointe-Garant P.P., Gosselin R., Simard J.S. and Abatzoglou N. (2013). Development of a multivariate light-induced fluorescence (LIF) PAT toolfor in-line quantitative analysis of pharmaceutical powders. European Journal of Pharmaceutics and Biopharmaceutics 86 (3), 524-531. (Published).
  • Abatzoglou N., Castellanos Gil E. and Gosselin R. (2013). The use of NIR Spectroscopy to evaluate the influence of hopper geometryon radial and axial concentration profiles in flowing granular mixtures. European Pharmaceutical Review (18), 33-38. (Published).
  • Eddy Castellanos Gil, Ryan Gosselin, Nicolas Abatzoglou. (2012). A NIRS Methodology to Measure Radial and Axial Concentration Profiles inFlowing Powder Mixtures. Powder Technology (224), 223-232. (Published).
  • Gosselin R., Lacombe M.O. and Abatzoglou N. (2012). Determining Bulk Powder Particle Size through Texture Analysis. American Pharmaceutical Review (1), 1-6. (Accepted).
  • Demers Anne-Marie, Gosselin Ryan, Simard Jean-Sébastien, Abatzoglou Nicolas. (2012). In-line near infrared spectroscopy monitoring of pharmaceutical powder moisture in a fluidised bed dryer: an efficient mehtodology for chemometric model development. Canadian Journal of Chemical Engineering 90 299-303. (Published).
  • A. Ziadi, X. Maldague, L. Saucier, C. Duchesne, R. Gosselin. (2011). Visible and Near-Infrared Light Transmission: a Hybrid Imaging Methodfor Non-destructive Meat Quality Evaluation. Infrared Physics & Technology (55), 412-420. (Published).
  • Gosselin R, Rodrigue D, Duchesne C. (2011). A hyperspectral imaging sensor for on-line quality control of extruded polymer composite products. Computers and Chemical Engineering 35 296-306. (Published).
  • Salvas Joanny, Simard Jean-Sébastien, Gosselin Ryan and Abatzoglou Nicolas. (2011). Calibration ofMultivariate Predictive Models: The Study of Factors Influencing the PredictionAccuracy of Raman Spectroscopy Applied to Pharmaceutical Tablets. American Pharmaceutical Review (1), 36-43. (Published).
  • Ryan Gosselin, Denis Rodrigue, Carl Duchesne. (2010). A Hyperspectral Imaging Sensor for On-line Quality Control of ExtrudedPolymer Composite Products. Computers & Chemical Engineering (35), 296-306. (Published).
  • Ryan Gosselin, Denis Rodrigue, Carl Duchesne. (2009). A Bootstrap-VIP Approach for Selecting Wavelength Intervals in Spectral ImagingApplications. Chemometrics and Intelligent Laboratory Systems (100), 12-21. (Published).
  • Ryan Gosselin, Denis Rodrigue, Ruben Gonzalez-Nunez, Carl Duchesne. (2009). Potential of Hyperspectral Imaging for Quality Control of Polymer BlendFilms. Industrial & Engineering Chemistry Research (48), 3033-3042. (Published).

Autres contributions

Gestion d'évènements

  • Chair. Colloquium on Recent Developments in Quality Control. (Conference).

Activités de collaboration internationale

  • Collaborator. The development process analytical technologies to complete quality by design (QbD) work in pharmaceutical processes. This work was carried out with B. Bataille at the Charles Gerhardt Institute in Montpellier. This collaboration has led to a PhD project and 2 papers published in international journals.


  • (2015). Parametric Study of Potassium Chloride Caking Tendency using Cake Break Energy. CSChE. Edmonton
  • (2015). Loglikelihood MCR for Low-Count Spectral Image Analysis. Conferentia Chemometrica. Budapest
  • (2015). A PAT-based Experimental methodology relating Velocity Profiles in Flowing Powder Mixtures with Cohesion/adhesion Parameters. IFPAC. Washington
  • (2015). An Automated Classification of Powder Agglomerates inside Capsules through X-ray Image Analysis. IFPAC. Washington
  • (2015). On-line Analysis of Multivitamin Powder Flows in a Tablet Press. IFPAC. Washington
  • (2015). Quantifying the Composition of Pharmaceutical Tablets using LIBS; the Importance of Matrix Effects. IFPAC. Washington
  • (2014). A methodology to Link Velocity Profiles of a Granulay System under Gravitational Flow with Cohesion/Adhesion Parameter. CSChE. Niagara Falls
  • (2014). Improving XPS spectrum image segmentation using multivariate analysis with statistical calculations and basic image processing. CSChE. Niagara Falls
  • (2014). Monitoring Multivitamin Powder Flows in a Tablet Press Using In-Line PAT tools. CSChE. Niagara Falls
  • (2014). Parametric Study of Dry Pharmaceutical Agglomeration during Blending. CSChE. Niagara Falls
  • (2014). Comparison of Principal Component Analysis and Multivariate Curve Resolution-Alternating Least Squares analysis of XPS spectral maps. Microscopy and Microanalysis. Hartford
  • (2014). A PAT-based Experimental Methodology Relating Velocity Profiles in Flowing Powder Mixtures with Cohesion/Adhesion Parameters. IFPAC. Washington
  • (2014). A PAT-based Experimental Methodology Relating Velocity Profiles in Flowing Powder Mixtures with Cohesion/Adhesion Parameters. IFPAC. Washington
  • (2014). Determining the Mineral Content of Pharmaceutical Multivitamin Tablets using LIBS. IFPAC. Washington
  • (2014). In-line Monitoring and Control Systems Designed to Ensure the On-demand Supply of Pharmaceutical Tablet Coating Solutions Prepared by an Automated Process Unit. IFPAC. Baltimore
  • (2013). Mineral quantification in pharmaceutical multivitamin tablets using XRF and LIBS. CSChE. Fredericton
  • (2013). Multivariate XPS imaging: Improving Data Post-Processing. Materials Science and Technology (MS&T),. Montreal
  • (2013). Residence Time Distribution and Concentration Profiles in Processes Involving Flowing Powders: Evaluating Segregation in Pharmaceutical Formulations. 6th Pan-European QbD & PAT Conference (EuPAT),. Porto
  • (2013). Développements récents de technologies d’analyse de procédés en génie pharmaceutique. Rencontres Montpellier-Sherbrook. Montpellier
  • (2013). Retombées scientifiques, techniques et économiques de l’utilisation de PAT sur un procédé pharmaceutique. Seminar in Engineering, Health and Analysis (SEHA). Algiers
  • (2013). A NIRS-based PAT Tool to Measure Radial and Axial Concentration Profiles in Processes Involving Flowing Powders: Prediction of Segregation Extent in Real Mixtures of Pharmaceutical Excipients. IFPAC. Baltimore
  • (2012). A PAT/QbD Approach to Measure Radial and Axial Concentration Profiles in Flowing Powder Mixtures using NIRS Analysis : A Case Study with Industrial Hoppers of Different Geometries. CSChE. Vancouver
  • (2012). In-line Monitoring and Control Systems Designed to Ensure the Quality of Pharmaceutical Coating Solutions. CSChE. Vancouver
  • (2012). Capabilities and Limitations of In-line Multivariate LIF Analyzer for Powder Monitoring. IFPAC. Baltimore
  • (2012). Using Wavelet Texture Analysis to Determine Bulk Powder Particle Size. IFPAC. Baltimore
  • (2011). Axial and Radial Composition Profiles in Flowing Particulate Mixtures. CSChE. London
  • (2011). Near Infrared Spectroscopy as a PAT Tool to Monitor in-line Pharmaceutical Powders in Fluid-bed Dryers. Stats and Control Meeting. Sherbrooke
  • (2009). Property Prediction of Wood/Plastic Composites through Spectral Imaging and Chemometrics Methods. 8th World Congress of Chemical Engineering. Montreal
  • (2009). Quality Control of Polymer Products through Spectral Imaging and Chemometrics Methods. ANTEC. Chicago
  • (2009). Application du principe de la qualité par la conception pour le contrôle qualité en industrie pharmaceutique. ACFAS. Sherbrooke
  • (2009). Développement d’un spectrofluoromètre multivarié pour l’analyse de produits pharmaceutiques. ACFAS. Sherbrooke