Ryan Gosselin

Financement

• Grant. (Awarded). Principal Investigator. Development and improvement of characterization methods to support the monitoring the aluminium production process Développement et amélioration de méthodes de caractérisation pour soutenir le suivi de procédé de production de l’aluminium. Mathematics of Information Technology and Complex Systems (MITACS). Acceleration. 300 000 $. (2024-2028)
• Grant. (Awarded). Co-applicant. Development of a Raman probe for allergen detection. Natural Sciences and Engineering Research Council of Canada (NSERC). Aliance. 1 500 000 $. (2023-2027)
• Grant. (Awarded). Co-applicant. Manufacturing of insulating polymer panels: integrated study linking the production line and sample microstructure Procédé de fabrication de mousses isolantes: étude intégrée liant la ligne de production à la microsctructure. Natural Sciences and Engineering Research Council of Canada (NSERC). Aliance. 618 000 $. (2023-2027)
• Grant. (Awarded). Principal Applicant. Calibration transfer in pharmaceutical process engineering. Natural Sciences and Engineering Research Council of Canada (NSERC). Discorery. 230 000 $. (2019-2025)
• Grant. (Awarded). Co-applicant. Experimental study of the factors influencing the stability of cement factories Étude expérimentale des facteurs influençant la stabilité de production du béton à l’usine. Mathematics of Information Technology and Complex Systems (MITACS). Acceleration. 240 000 $. (2021-2024)
• Grant. (Awarded). Co-applicant. Understanding, modelling and optimizing pharmaceutical production processes implying divided solids (Compréhension, modélisation et optimisation de procédés de production pharmaceutique impliquant des solides divisés). Natural Sciences and Engineering Research Council of Canada (NSERC). Pfizer. Cash contribution. 487 834 $. (2018-2023)
• Grant. (Awarded). Co-applicant. Porous Germanium Efficient Epitaxial Layer Release (PEELER) for low cost high performance III-V solar cells. Natural Sciences and Engineering Research Council of Canada (NSERC). Collaborative Research and Development. 959 999 $. (2019-2022)
• Grant. (Awarded). Co-applicant. A hyperspectral Raman imaging systems for process analytical technology developments. Natural Sciences and Engineering Research Council of Canada (NSERC). RTI. 115 244 $. (2021-2021)
• Grant. (Awarded). Co-applicant. A hyperspectral Raman imaging systems for process analytical technology developments. Natural Sciences and Engineering Research Council of Canada (NSERC). RTI. 115 224 $. (2021)
• Grant. (Completed). Principal Investigator. "Développement de méthodes multivariées pour l'analyse de données comportant des variations spatiotemporelles" "Development of multivariate methods for the analysis of data presenting spatiotemporal variations". Mathematics of Information Technology and Complex Systems (MITACS). Accélération. 40 000 $. (2018-2020)
• Grant. (Completed). Co-applicant. "Paradigm shift for allergen management thanks to the development of ultra-sensitive molecular probes" "Changement de paradigme pour la gestion des allergènes grâce au développement de sondes moléculaires ultra-sensibles". Fonds de recherche du Québec - Nature et technologies (FRQNT). Audace. 100 000 $. (2019-2020)
• Grant. (Completed). Principal Investigator. Freeze-drying of antibiotic vials: monitoring and optimizing process trajectories on an industrial scale. Mathematics of Information Technology and Complex Systems (MITACS). Elevation. 81 000 $. (2017-2019)
• Grant. (Completed). Principal Investigator. Algorithmic development for Raman imaging applied to pharmaceutical engineering (Développement algorithmiques en imagerie Raman appliqués en génie pharmaceutique). Mathematics of Information Technology and Complex Systems (MITACS). Elevation. 110 000 $. (2017-2018)
• Grant. (Completed). Co-applicant. Rhéologie de matériaux utilisés dans des procédés de granulation humide. Natural Sciences and Engineering Research Council of Canada (NSERC). RTI - Research Tools and Instruments. 148 000 $. (2016)

Publications

Articles de revue

• Ahmed Ramadan, Nicolas Abatzoglou, Ryan Gosselin. (2025). Addressing Temperature Variations of Miniaturized NIR Spectrometers: Advancing Quantitative Models for Pharmaceutical Analysis. Journal of Pharmaceutical and Biomedical Analysis (Accepted).
• Ahmed Ramadan, Giverny Robert, Romain Kersaudy, Maroua Rouabah, Nicolas Abatzoglou, Ryan Gosselin. (2025). Calibration transfer and maintenance in the pharmaceutical industry; a systematic review. European Journal of Pharmaceutical Sciences (Accepted).
• Karakache S.B., Rouabah M., Gosselin R., Abatzoglou N., Achouri I.E. (2025). Experimental Study and Statistical Analysis of Hydrogen Yield in Methane Steam Reforming over Hydroxyapatite Supported Nickel Catalyst. Catalysis Today (Published).
• Robert G. and Gosselin R. (2024). Calibration transfer by likelihood maximization: A standard-free method for multiple instruments. Infrared Physics and Technology 140 (145386), (Published).
• Aboagye B., Gosselin R., Wilson W. (2024). Replacement of Natural Sand with Manufactured Sand While Maintaining Packing Density. American Concrete Institute 362 189-201. (Published).
• Lavoie F.B., Robert G. and Gosselin R. (2023). Calibration transfer by likelihood maximization: A standard-free approach capable of handling non-overlapping wavelength ranges. Chemometrics and Intelligent Laboratory Systems (Published).
• Perluzzi M., Wilson, W, Gosselin R. (2023). Impact of data grouping on the multivariate analysis of multiple concrete plants. Processes (Published).
• Koumbogle K., Gosselin R., Gitzhofer F., and Abatzoglou N. (2023). Moisture behavior of pharmaceutical powder during the tableting process. Pharmaceutics 15 (6), 1652. (Published).
• Koumbogle K., Gosselin R., Gitzhofer F., and Abatzoglou N. (2023). Moisture behavior of pharmaceutical powder during the tableting process. Pharmaceutics (Published).
• Koumbogle K., Gosselin R., Gitzhofer F., and Abatzoglou N. (2023). The effect of tableting Process Parameters and Powder Lubrication Levels on Tablet Surface Temperature and Moisture Content. Pharmaceutical Development and Technology 28 (10), 992-999. (Published).
• Koumbogle K., Gosselin R., Gitzhofer F., and Abatzoglou N. (2023). The effect of tableting Process Parameters and Powder Lubrication Levels on Tablet Surface Temperature and Moisture Content. Pharmaceutical Development and Technology (Submitted).
• Paupy N., Elhmaidi Z.O., Chapotot A., Hanuš T., Arias-Zapata J., Ilahi B., Heintz A., Poungoué Mbeunmi A.B., Arvinte R., Aziziyan M.R., Daniel V., Hamon G., Chrétien J., Zouaghi F., Ayari A., Mouchel L., Henriques J., Demoulin L., Diallo T.M., Provost P.O., Pelletier H., Volatier M., Kurstjens R., Cho J., Courtois G., Dessein K., Arcand S., Dubuc C., Jaouad A., Quaegebeur N., Gosselin R., Machon D., Arès R., Darnon M. Boucherif A. (2023). Wafer-scale detachable monocrystalline Germanium nanomembranes for the growth of III-V materials and substrate reuse. Nanoscale Advances (Published).
• Dembele M., Hudon S., Simard J.S., Abatzoglou N. and Gosselin R. (2022). A multivariate data analysis approach to tablet sticking on an industrial scale: A qualitative case study of an ibuprofen-based formulation. Pharmaceutical Development & Technology (Published).
• Mohammed A, Cournoyer A., Gosselin R. (2022). An investigation into the spatial distribution of moisture in freeze-dried products using NIR chemical imaging and spectroscopy. Journal of Pharmaceutical Science and Technology (Published).
• Fauteux-Lefebvre C., Hudon S. and Gosselin R. (2022). Characterization of tablet composition by Raman mapping and hierarchical multivariate curve-resolution. Journal of Pharmaceutical Innovation (Published).
• Robert G. and Gosselin R. (2022). Evaluating the impact of NIR pre-processing methods via multiblock partial least-squares. Analytica Chimica Acta (Published).
• Dembele M., Hudon S., Simard J.S., Abatzoglou N. and Gosselin R. (2022). Insights into tablet sticking: a quantitative case study with an ibuprofen and methocarbamol-based formulation. Pharmaceutical Development and Technology (Published).
• Pharmaceutical Development and Technology. (2022). Pharmaceutical tablet compression: measuring temporal and radial concentration profiles to better assess segregation. Robert G., Dalvi H., Lavoie F.B., Abatzoglou N., Gosselin R. (Published).
• Ly A., Achouri I.E., Gosselin R. and Abatzoglou N. (2022). Sequential Fixed-Fluidized Bed Foam Granulation (SFFBFG) and Drying: Multivariate Model Development for Water Content Monitoring with Near–Infrared Spectroscopy. Chemical Engineering Science (Published).
• Robert G. and Gosselin R. (2021). Evaluating the impact of NIR pre-processing methods via multiblock partial least-squares. Analytica Chimica Acta 1189 339255. (Published).
• Chaib O., Achouri I., Gosselin R. and Abatzoglou N. (2021). Gravity mass powder flow through conical hoppers. Part II: A mathematical model predicting the axial and radial profiles of normal stresses from flow velocity measurements. Canadian Journal of Chemical Engineering 99 1654-1662. (Published).
• Chaib O., Achouri I., Gosselin R. and Abatzoglou N. (2021). Gravity mass powder flow through conical hoppers Part I: A mathematical model predicting the radial velocity profiles of free-flowing granular systems as a function of cohesion and adhesion properties. Canadian Journal of Chemical Engineering 99 1643-1653. (Published).
• Mohammed A., Cournoyer R., Gosselin R. (2021). Identifying Collapse in Freeze-Dried Products Via NIR Spectroscopy. American Pharmaeutical Review April (Published).
• Achouri I.E., Rhoden A., Hudon S., Gosselin R., Simard J.S. and Abatzoglou N. (2021). Non-invasive sensing technologies applicable for pharmaceutical lyophilized products: a review. Talanta 224 121885. (Published).
• Ly A., Achouri I. Gosselin R., Abatzoglou N. (2021). Wet granulation end-point prediction using dimensionless numbers in a mixer torque rheometer: relationship between capillary and Weber numbers and the optimal wet mass consistency. International Journal of Pharmaceutics 605 120823. (Published).
• Vielfaure A. Cournoyer A. and Gosselin R. (2020). Extracting meaningful patterns from noisy spatiotemporal datasets with Multivariate Curve Resolution. Industrial & Engineering Chemistry Research 59 (Published).
• Simoneau J., Gosselin R. and Scott M. (2020). Factorial study of the RNA-seq computational workflow identifies biases as technical gene signatures. NAG Genomics and Bioinformatics 2 (2), 1-18. (Published).
• Ly A., Achouri I.E., Gosselin R. and Abatzoglou N. (2020). Rheological behavior of porous pharmaceutical materials: linking torque profiles during wet massing to water diffusion coefficients and penetration time. Chemical Engineering and Processing - Process Intensification 157 108152. (Published).
• Lavoie F.B.*, Muteki K. and Gosselin R. (2019). A Novel Robust NL-PLS Regression Methodology. Chemometrics and Intelligent Laboratory Systems (Published).
• Santos Silva B.*, Santangelo M., Colbert M.J., Fauteux-Lefebvre C., Bartlett J.A., Lapointe-Garant P.P., Abatzoglou N., Gosselin R. (2019). Building process understanding of fluid bed coating of microspheres for pediatric formulations. AAPS PharmSciTech (Published).
• Lavoie F.B.*, Muteki K. and Gosselin R. (2019). Computing Meaningful Models of Continuous Data. Chemical Engineering Research and Design (Published).
• Simoneau J.*, Dumontier S.*, Gosselin R. and Scott M. (2019). Current RNA-seq methodology reporting limits reproducibility. Briefings in Bioinformatics (Published).
• Dalvi H.*, Langlet A.*, Colbert M.J.*, Cournoyer A., Guay J.M., Abatzoglou N. and Gosselin R. (2019). In-line monitoring of Ibuprofen during and after tablet compressionusing Near-Infrared spectroscopy. Analytical Chemistry (Published).
• Lavoie F.B.*, Muteki K., Langlet A. and Gosselin R. (2019). Likelihood Maximization Inverse Regression: A Novel Non-Linear Multivariate Model. Analytica Chimica Acta (Published).
• Santos Silva B.,* Colbert M.J., Santangelo M., Bartlett J.A., Lapointe-Garant P.P., Gosselin R. (2019). Monitoring microsphere coating processes using PAT tools in a bench scale fluid bed: end point determination using process trajectory. European Journal of Pharmaceutics and Biopharmaceutics (Published).
• Braidy N. and Gosselin R. (2019). Unmixing noisy co-registered spectrum images of multicomponent nanostructures. Scientific Reports 9 18797. (Published).
• Fauteux-Lefebvre C.* Lavoie F.B.* and Gosselin R. (2018). A Hierarchical Multivariate Curve Resolution Methodology to Identify andMap Compounds in Spectral Images. Analytical chemistry (Published).
• Dalvi H.*, Fauteux-Lefebvre C.*, Guay, J.M., Abatzoglou N. and Gosselin R. (2018). Concentration Monitoring with Near Infrared Chemical Imaging in a Tableting Press. Journal of Spectral Imaging 7 1-18. (Published).
• Kikongi P.*, Fauteux-Lefebvre C.*, Salvas J. and Gosselin R. (2018). DetectingTrace Levels of Heavy Metals in Pharmaceutical Raw Materials withWavelength-dispersive X-ray Fluorescence spectroscopy and curve-fitting regression. Spectrochimica Acta Part B 147 59-70. (Published).
• Lavoie F.B.*, Muteki K. and Gosselin R. (2018). Generalizationof Powered-Partial-Least-Squares. Chemometrics and Intelligent Laboratory Systems 179 1-11. (Published).
• Langlet A.*, Dalvi H.*, Cournoyer A., Guay J.M. and Gosselin R. (2018). NIR inspection of each tablet coming off a tablet press. European Pharmaceutical Review (Published).
• Vachon-Lachance E.*, Abatzoglou N., Gosselin R., Duchesne C. and Cournoyer A. (2018). Potassium Chloride Caking Tendency: a Parametric Study using Cake Break Energy. Advanced Powder Technology 29 (9), 2140-2152. (Published).
• Durao P.*, Fauxteux-Lefebvre C.*, Guay J.M., Abatzoglou N. and Gosselin R. (2018). Specificity of Process Analytical Tools in the monitoring of multicomponent pharmaceutical powders. Pharmaceutical Development and Technology DOI: 10.1080/1083745 (Published).
• Kikongi P.*, Salvas J. and Gosselin R. (2017). Curve-fitting regression : improving light element quantification with XRF. X-ray Spectrometry 46 (5), 347-355. (Published).
• Yekpe K.*, Abatzoglou N., Bataille B., Gosselin R., Sharkawi T. Simard J.S., Cournoyer A. (2017). Developing a Quality by Design Approach to Model Tablet Dissolution Testing: an Industrial Case Study. Pharmaceutical Development and Technology 2 1-9. (Published).
• Gosselin R. Vachon-Lachance E.*, Cournoyer A. and Clarke F. (2016). Classifying Pharmaceutical Capsules Through X-Ray Image Analysis Based on Agglomeration of their Contents. Journal of Pharmaceutical Innovation 11 92-101. (Published).
• Lavoie F.B.*, Braidy N. and Gosselin R. (2016). Including Noise Characteristics in MCR to improve Mapping and Component Extraction from Spectral Images. Chemometrics and Intelligent Laboratory Systems 153 40-50. (Published).
• Lagos D.A.*, Héroux M., Gosselin R. and Cabral A.R. (2016). Optimization of a Landfill Gas Collection Shutdown based on an Adapted First-order Decay Model. Waste Management 63 238-245. (Published).
• Durao P.*, Fauxteux-Lefebvre C.*, Guay J.M., Abatzoglou N. and Gosselin R. (2016). Using multiple Process Analytical Technology probes to monitor multivitamin blends in a tableting feed frame. Talanta 164 7-15. (Published).
• Chaib O.*, Abatzoglou N. and Gosselin R. (2015). Applicationof NIR Spectroscopy in Linking Velocity Profiles of a Binary Granular System. European Pharmaceutical Review 20 (4), 51-60. (Published).
• Palmero-Durao P*. Abatzoglou N., Guay J.M. and Gosselin R. (2015). Monitoring the Concentration of Flowing Pharmaceutical Powders in a Tableting Feed Frame. Pharmaceutical Development and Technology (Published).
• Yekpe K.*, Abatzoglou N., Bataille B., Gosselin R., Sharkawi T., Simard J.S., Cournoyer A. (2015). Predicting the dissolution behavior of pharmaceutical tablets with NIRchemical imaging. International Journal of Pharmaceutics (486), 242–251. (Published).
• Guay J.M.*, Lapointe-Garant P.P., Gosselin R., Simard J.S. and Abatzoglou N. (2014). Development of a multivariate light-induced fluorescence (LIF) PAT toolfor in-line quantitative analysis of pharmaceutical powders. European Journal of Pharmaceutics and Biopharmaceutics 86 (3), 524-531. (Published).
• Abatzoglou N., Castellanos Gil E.*, Gosselin R. (2014). Influence of Hopper Geometry on Radial and Axial Concentration Profiles in Flows of Segregated and Homogenized Granular Mixtures. Powder Technology (262), 42-50. (Published).
• Gosselin R., Abatzoglou N., Quinn P.*, Salvas J. and Simard J.S. (2014). Novel methodologies for determining the mineral content of complex multivitamin tablets. European Pharmaceutical Review 19 (4), 62-68. (Published).
• Abatzoglou N., Gosselin R., Inam, M.A.*. (2014). Rheological Characterization and Empirical Modelling of Non-Acqueous Nano-Suspensions of Iron Carbide Produced by Plasma Spray. Chemical Engineering Journal 92(1) 68-74. (Published).
• Gosselin R., Lacombe M.O.*, Abatzoglou N. (2013). Determining Bulk Powder Particle Size through Texture Analysis. American Pharmaceutical Review (1), 1-6. (Published).
• Abatzoglou N., Castellanos Gil E.*, Gosselin R. (2013). The use of NIR Spectroscopy to evaluate the influence of hopper geometryon radial and axial concentration profiles in flowing granular mixtures. European Pharmaceutical Review (18), 33-38. (Published).
• Castellanos Gil E.*, Gosselin R., Abatzoglou R. (2012). A NIRS Methodology to Measure Radial and Axial Concentration Profiles in Flowing Powder Mixtures. Powder Technology (224), 223-232. (Published).
• Demers A.M.*, Gosselin R., Simard J.S., Abatzoglou N. (2012). In-line near infrared spectroscopy monitoring of pharmaceutical powder moisture in a fluidised bed dryer: an efficient mehtodology for chemometric model development. Canadian Journal of Chemical Engineering 90 299-303. (Published).
• Ziadi A.*, Maldague X., Saucier L., Duchesne C., Gosselin R. (2012). Visible and Near-Infrared Light Transmission: a Hybrid Imaging Methodfor Non-destructive Meat Quality Evaluation. Infrared Physics & Technology (55), 412-420. (Published).
• Gosselin R, Rodrigue D, Duchesne C. (2011). A hyperspectral imaging sensor for on-line quality control of extruded polymer composite products. Computers and Chemical Engineering 35 296-306. (Published).
• Salvas J.*, Simard J.S., Gosselin R., Abatzoglou N. (2011). Calibration of Multivariate Predictive Models: The Study of Factors Influencing the Prediction Accuracy of Raman Spectroscopy Applied to Pharmaceutical Tablets. American Pharmaceutical Review (1), 36-43. (Published).
• Ryan Gosselin, Denis Rodrigue, Carl Duchesne. (2010). A Hyperspectral Imaging Sensor for On-line Quality Control of ExtrudedPolymer Composite Products. Computers & Chemical Engineering (35), 296-306. (Published).
• Ryan Gosselin, Denis Rodrigue, Carl Duchesne. (2009). A Bootstrap-VIP Approach for Selecting Wavelength Intervals in Spectral ImagingApplications. Chemometrics and Intelligent Laboratory Systems (100), 12-21. (Published).
• Ryan Gosselin, Denis Rodrigue, Ruben Gonzalez-Nunez, Carl Duchesne. (2009). Potential of Hyperspectral Imaging for Quality Control of Polymer BlendFilms. Industrial & Engineering Chemistry Research (48), 3033-3042. (Published).

Articles de conférence

• Aboagye B. Gosselin R., and Wilson W. (2024). Replacement of Natural Sans with Manufactured Sand while Maintaining Packing Density. International Conference on Cementitious Materials. (Submitted).
• Voisard F., Gosselin R., Dluhos J., Tesařová H., Bertschová V., Braidy N. (2022). Interpretation of 3D EDX maps: multivariate analysis and deep learning hybrid approach. Japan-Canada Joint Seminar on Advanced Electron Microscopy and its Application. (Published).
• Demoulin L., Zapata J.A., Boucherif A. and Gosselin R. (2022). Study of Mesoporous Germanium Porosification by Fast Bipolar Electrochemical Etching using Statistical Design of Experiments. Porous Semiconductors Science and Technology (PSST). (Published).
• Lavoie F.B., Proulx P. and Gosselin R. (2019). Using Data Acquired from Learning Management Systems to Predict Examination Results. CEEA – ACEG. (Published).
• Braidy N., Lavoie F.B.* and Gosselin R. (2018). Combined EELS and EDX datasets probed by advanced data mining techniques. 19th International Microscopy Congress. (Accepted).
• Kikongi P.*, Byrns J.*, Yen, E., Piché N., Gosselin R. and Braidy N. (2018). DragonflyHyperspectral and Hypermodal Data Visualization Using new Hyperdimensionalenvironment. Microscopy & Microanalysis. (Accepted).
• Kikongi P.*, Dumaresq N.*, Lavoie F.B.*, Gosselin R. and Braidy N. (2018). Metallic Copper Clusters Decorating Cu Ferrites Revealed by Deep DataAnalysis. Microscopy & Microanalysis. (Accepted).
• Lavoie F.B.*, Gosselin R. and Braidy N. (2016). Insights on MultivariateStatistics to Improve Spectrum Image Analysis. Microscopical Society of Canada Annual Meeting. (Published).
• Lagos D.A.*, Héroux M., Gosselin R. and Cabral A.R. (2016). Optimization of Shutdown of Landfill Gas Collection based on 20 years of data in a Landfill Accepting Wastes whose Composition varied with Time, Intercontinental Landfill Research Symposium. Intercontinental Landfill Research Symposium. (Published).
• Quinn P.*, Abatzoglou N. Salvas J. and Gosselin R. (2014). Analysis of LIBS Matrix Effects in Binary Particulate Mixtures. American Association of Pharmaceutical Scientists (AAPS) Meeting. (Published).
• Lavoie F.B.*, Braidy N., Blais, S. and Gosselin R. (2014). Comparison of Principal Component Analysis and Multivariate Curve Resolution-Alternating Least Squares analysis of XPS spectral maps. Microscopy and Microanalysis. (Published).
• Vachon-Lachance E.*, Gosselin R., Cournoyer A., Duchesne C. and Abatzoglou N. (2014). Dry Powder Agglomeration Mechanisms duringPharmaceutical Blending. AAPS. (Published).
• Gosselin R., Fauteux-Lefebvre C.* and Abatzoglou N. (2013). Multiples Rôles de l’Étudiant dans un Cour de Laboratoire : Perceptions des Étudiants,Questions de Pédagogie dans l’Enseignement Supérieur. Canadian Engineering Education Association Conference. (Published).
• Yekpe K.*, Cournoyer A., Simard J.S., Gosselin R., Sharkawi T., Bataille B., Abatzoglou N. (2013). Quality by DesignApproach to Demonstrate Tablet Manufacturing Process Robustness. AAPS. (Published).
• Lapointe-Garant P.P., Simard J.S., Belley S.*, Abatzoglou N., Gosselin R., Perrier M. (2013). The Concept of Flexible Manufacturing as Illustrated by an On-demand Production Unit for a Tablet Coating Solution. AAPS. (Published).
• Quinn P.*, Gosselin R., Abatzoglou N., Salvas J. and Simard J.S. (2013). XRF and LIBS for mineral quantification in pharmaceutical multivitamin tablets. 6th Pan-European QbD & PAT Conference (EuPAT). (Published).
• Abatzoglou N., Castellanos-Gil E.*, Gosselin R. (2012). A NIRS-based PAT tool to measure radial and axial concentration profiles in flowing powder mixtures: First results and Modelling efforts. International Forum on Process Analytical Chemistry (IFPAC). (Published).
• Guay J.M.*, Gosselin R., Lapointe-Garant P.P., Abatzoglou N. (2012). Capabilities and Limitations of an In-line Multivariate LIF Analyzer for Powder Monitoring. CSChE. (Published).
• Yekpe K.*, Abatzoglou N., Bataille B., Gosselin R., Sharkawi T., Simard J.S. (2012). Investigation of Turbidimetry as a Possible PAT Tool to Measure Disintegration Profiles of Finished Solid Products. World meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. (Published).
• Gosselin R., Lacombe M.O. (2011). Inferring Particle SizeDistribution of Bulk Powders using Texture Analysis and Chemometrics Methods. International Chemometrics Research Meeting. (Accepted).
• Gosselin R., Rodrigue D. and Duchesne C. (2010). Hyperspectral Imaging forMonitoring and Quality Control in the Process Industry. Chemometrics in Analytical Chemistry (CAC). (Accepted).
• Gosselin R., Simard J.S., Cournoyer A. and Abatzoglou N. (2010). On-line Liquid Ingredientconcentration Monitoring of Multi-Component Pharmaceutical Products usingUV-ATR Technology. Chemometrics in Analytical Chemistry (CAC). (Accepted).

Autres contributions

Gestion d'évènements

• Chair. (2011) Colloquium on Recent Developments in Quality Control. (Conference).

Activités de collaboration internationale

• Collaborator. United States of America. Development of a palatable dosage form for pediatric use by fluid bed coating of multiparticulates : work with the Pediatric Formulation Group, Pfizer Research Center in Groton, CT, USA.
• Collaborator. United States of America. Multivariate Data Analysis and Integration of a Pharmaceutical Continuous Manufacturing Unit : work with the Worldwide Research and Development Group, Pfizer Research Center in Groton, CT, USA.
• Collaborator. France. The development process analytical technologies to complete quality by design (QbD) work in pharmaceutical processes. This work was carried out with B. Bataille at the Charles Gerhardt Institute in Montpellier. This collaboration has led to a PhD project and 2 papers published in international journals.

Présentations

• Romain Charière, Stephan Freiberg, Ryan Gosselin and Nadi Braidy. (2025). Minimizing stereological bias in cellular materials: from 2D metrology to 3D statistical descriptors evaluation. Microscopy Society of Canada annual Meeting. Winnipeg, Canada
• Adrien Martinez, Ryan Gosselin, Nadi Braidy. (2025). P-LLM: Unsupervised Poisson‐Likelihood Blind Source Separation for Low-Count TEM–EELS Hyperspectral Imaging. Microscopy Society of Canada annual Conference. Winnipeg, Canada
• Ramadan A., Abatzoglou N. Gosselin R. (2024). Addressing Temperature Variation of Miniaturized NIR Spectrometers: Advancing Quantitative Models for Pharmaceutical Analysis. Canadian Society for Chemical Engineering (CSChE). Toronto, Canada
• Ramadan A., Abatzoglou N., Gosselin R. (2024). Advancing Calibration Transfer in the Pharmaceutical Industry: A Systematic Review and Future Research Directions. Stats and Control Meeting. Montreal, Canada
• Lavoie F.B., Voisard F., Gosselin R., Braidy N. (2024). Artificial intelligence to improve segmentations of spectral image datasets. MSC-SMC Meeting. Ottawa, Canada
• Aboagye B. Gosselin R., Wilson W. (2024). Investigation of aggregate packing density with manufactured sand as partial replacement of natural sand. 12th International Conference on Cementitious Materials (ICCM). France
• Kersaudy R., Rouabah M. Ly A., Achouri I.E., Gosselin R., Abatzoglou N. (2024). Use of in-line MicroNIR spectroscopy to predict granule size during foam granulation and drying performed in fluidized bed reactor. Canadian Society for Chemical Engineering (CSChE). Ottawa, Canada
• Robert G., Abatzoglou N., Gosselin R. (2023). Calibration transfer based on likelihood maximization: a standard-free method for multiple instruments. Stats and Control Meeting. Waterloo, Canada
• Demoulin L., Zapata J.A., Aziziyan M.R., Gosselin R., Cho J., Dessein K. and Boucherif A. (2023). Electrochemical etching study of mesoporous germanium through statistical design of experiments. Colloque Annuel sur la Recherche des Matériaux Fonctionnels (CQMF-QCAM). Victoriaville, Canada
• Voisard F., Gosselin R., Dluhos J., Tesařová H., Braidy N. (2023). Interpretation of serial section 3D EDX maps: multivariate analysis and deep learning hybrid approach. International Union of Microban Analysis Societies Joint with the Annual Microscopical Society of Canada and FIB SEM Meetings. Banff, Canada
• Aboagye B. Gosselin R., and Wilson W. (2023). Replacement of Natural Sans with Manufactured Sand while Maintaining Packing Density. International Conference on Cementitious Materials. Toulouse, France
• Demoulin L., Zapata J.A., Aziziyan M.R., Gosselin R., Cho J., Dessein K. and Boucherif A. (2023). Statistical design of experiments to study the impact of electrochemical etching parameters on mesoporous Ge properties. Canadian Semiconductor Science and Technology Conference (CSSTC). Montreal, Canada
• Robert G., Abatzoglou N., Gosselin R. (2022). Calibration transfer based on likelihood maximization. CSChE. Vancouver, Canada
• Robert G., Abatzoglou N., Gosselin R. (2022). Calibration transfer based on likelihood maximization. Stats and Control Meeting. Quebec, Canada
• Voisard F., Gosselin R., Dluhos J., Tesařová H., Bertschová V., Braidy N. (2022). Interpretation of 3D EDX maps: multivariate analysis and deep learning hybrid approach. Japan-Canada Joint Seminar on Advanced Electron Microscopy and its Application. Okayama, Japan
• Perluzzi M., Wilson W., and Gosselin R. (2022). Multivariate analysis of the critical parameters influencing the production of concrete. Stats and Control Meeting. Quebec, Canada
• Ly A., Achouri I.E., Gosselin R., Abatzoglou. N. (2022). Sequential Fixed Fluidized Bed Foam Granulation (SFFBFG) and Drying: Multivariate Model Development for Water content Monitoring with Near-Infrared Spectroscopy. CSChE. Vancouver, Canada
• Ly A., Achouri I.E., Gosselin R., Abatzoglou. N. (2022). Sequential Fixed Fluidized Bed Foam Granulation (SFFBFG) and Drying: Multivariate Model Development for Water content Monitoring with Near-Infrared Spectroscopy. AICHE. Phoenix, United States of America
• Demoulin L., Zapata J.A., Boucherif A. and Gosselin R. (2022). Study of Mesoporous Germanium Porosification by Fast Bipolar Electrochemical Etching using Statistical Design of Experiments. Porous Semiconductors Science and Technology (PSST) Conference. Versilia Lido, Italy
• Fauteux-Lefebvre C., Lavoie F.B., Gosselin R. (2021). Analyse Raman de comprimés pharmaceutiques. ACFAS. Sherbrooke, Canada
• Dembélé M., Abatzoglou N., Gosselin R. (2021). Etude multivariée du collage de poudres pharmaceutiques. ACFAS. Sherbrooke, Canada
• Robert-Bigras G., St-Pierre L., Tang N., Kaswan S., Casteignau F., Braidy N., Théolier J., Martel R. and Gosselin R. (2021). Imageur Raman via Raman. ACFAS. Sherbrooke, Canada
• Dembele M., Abatzoglou N. and Gosselin R. (2021). Multivariate data analysis provides insights into tablet sticking. CSChE. Montreal, Canada
• Robert G., Dalvi H., Lavoie F.B., Abatzoglou N. and Gosselin R. (2021). Pharmaceutical tablet compression: measuring temporal and radial and concentration profiles to better detect segregation. CSChE. Montreal, Canada
• Ly A., Gosselin R., Achouri E., Abatzoglou N. (2021). Relation entre le nombre capillaire et la consistance développée dans un mixer torque rheometer pour la prédiction du point final de la granulation humide. ACFAS. Sherbrooke, Canada
• Ly A., Achouri E., Gosselin R. and Abatzoglou N. (2021). Relationship between the capillary number and the optimal wet mass consistency developed in a Mixer Torque Rheometer for the wet granulation end point prediction. CSChE. Montreal, Canada
• Colbert M.J., Kikongi P., Braidy N., Gosselin R. (2020). Blind identification and mapping of compounds present in spectral imagesBlind identification and mapping of compounds present in spectral images. MSC-SMC Symposium. Sherbrooke, Canada
• Ly A., Gosselin R., Abatzoglou N. (2020). Rheological behavior of porous pharmaceutical materials: linking torque profiles during wet massing to water penetration time. CSChE. Montreal, Canada
• Lavoie F.B., Muteki K., Gosselin R. (2019). Dynamic-PLS Algorithm for Meaningful Models. Scandinavian Symposium on Chemometrics. Oslo, Norway
• Simoneau J., Dumontier S., Gosselin R., Scott M. (2019). Genomic Annotations, an Uninformed Design Choice for Experimentalists, Great Lakes Bioinformatics Conference. Great Lakes Bioinformatics Conference. Madison, Wisconsin, USA, United States of America
• Dalvi H., Langlet A., Guay J.M., Cournoyer A., Abatzoglou N. and Gosselin R. (2019). Monitoring of a Tabletting Feed Frame using NIR Spectroscopy and Chemical Imaging. IFPAC. North Bethesda, Maryland, USA, United States of America
• Santos Silva B., Gosselin R., Fauteux-Lefebvre C., Santangelo M., Lapointe-Garant P.P. and Bartlett J. (2019). Monitoring the coating process of an easy-to-swallow dosage form for pediatric use. IFPAC. North Bethesda, Maryland, United States of America
• Simoneau J., Dumontier S., Gosselin R., Scott M. (2019). RNA-seq methodological landscape: the ignored importance of the choice of genome annotations. European Conference on Computational Biology. Basel, Switzerland, Switzerland
• Gosselin R., Guay J.M., Cournoyer A., Durao P., Dalvi H., Abatzoglou N. (2019). Real-time monitoring of powders in a tablet press: Proof-of-concept towards implementation. IFPAC. North Bethesda, Maryland, USA, United States of America
• Lavoie F.B., Proulx P. and Gosselin R. (2019). Using Data Acquired from Learning Management Systems to Predict Examination Results. CEEA – ACEG. June 9-12, Ottawa, Canada, Canada
• Rudinsky S., Yuan Y., Lavoie F.B., Gauvin R., Gosselin R., Braidy N., Piché N., Marsh M. (2019). Using Deep Learning to Deconvolute Complex Spectra for Hyperspectral Imaging Applications. Microscopy & Microanalysis (M&M). Oregon, USA, United States of America
• Lavoie F.B.*, Muteki K. and Gosselin R. (2018). A Novel Nonlinear PLS Algorithm to Calculate Robust and Simple Predictive Models. Chemometrics in Analytical Chemistry. Halifax, Canada
• Braidy N., Lavoie F.B.* and Gosselin R. (2018). Combined EELS and EDX datasets probed by advanced data mining techniques. 19th International Microscopy Congress. Sydney, Australia
• Kikongi P.*, Dumaresq N.*, Lavoie F.B.*, Gosselin R. and Braidy N. (2018). Metallic Copper Clusters Decorating Cu Ferrites Revealed by Deep Data Analysis. Microscopy & Microanalysis. Baltimore, United States of America
• Fauteux-Lefebvre C., Lavoie F.B., Colbert M.J., Guay J.M. and Gosselin G. (2017). Determining the Number of Components for Multivariate Curve Resolution: Case Study Using Raman Mapping of (Pharmaceutical) Tablets. Microscopy & Microanalysis. St-Louis, United States of America
• Kikongi P., Choinière-Denicourt M., Demers H., Gauvin R., Gosselin R. and Braidy N. (2017). Mapping Data with Heavily Overlapped Spectral Features. Microscopy & Microanalysis. St-Louis, United States of America
• Durao P.*, Dalvi H.*, Guay J.M., Abatzoglou N., and Gosselin R. (2017). Multi-probe Monitoring of a Tableting Feed Frame. IFPAC. North Bethesda, Maryland, United States of America
• Fauteux-Lefebvre C., Lavoie F.B., Hudon S., Chen C., Guay J.M. and Gosselin R. (2017). Using Raman Chemical Imaging to Evaluate Phamarceutical Process Alternatives. Canadian Microscopy & Cytometry Symposium. Montreal, Canada
• Kikongi P., Gosselin R., Salvas J. and Blais S. (2016). Curve Fitting Regression, a novel way to Quantify Boron using WD-XRF. European Conference on X-Ray Spectrometry,. Gothenburg, Sweden
• Lavoie F.B., Gosselin R. and Braidy N. (2016). Extracting Components from Spectrum Images. Microscopy Society of Canada Conference. Edmonton, Canada
• Santos-Siva B.*, Abatzoglou N., Lapointe-Garant P.P., Santangelo M., Bartlett J. and Gosselin R. (2016). Fluid Bed Coating of Microspheres for Pediatric Dosage Forms. CSChE. Quebec, Canada
• Fauteux-Lefebre C., Lavoie F.B., Guay J.M. et Gosselin R. (2016). Mapping the 3D composition of Tablet using Raman Imaging doesn’t need to be Slow. IFPAC. Washington, United States of America
• Lagos D.A., Héroux M., Gosselin R. and Cabral A.R. (2016). Optimization of Shutdown of Landfill Gas Collection based on 20 years of data in a Landfill Accepting Wastes whose Composition varied with Time. Intercontinental Landfill Research Symposium. Hokkaido, Japan
• Lavoie F.B., Muteki K., Gosselin R. (2016). Revisiting Dynamic PLS : Creating Meaningful and Accurate Models. Stats and Control Meeting. Waterloo, Canada
• Abatzoglou N., Chaib O, Gosselin R. (2015). A PAT-based Experimental methodology relating Velocity Profiles in Flowing Powder Mixtures with Cohesion/adhesion Parameters. IFPAC. Washington, United States of America
• Gosselin R. Vachon-Lachance E.*, Cournoyer A., Clarke F. (2015). An Automated Classification of Powder Agglomerates inside Capsules through X-ray Image Analysis. IFPAC. Washington, United States of America
• Lavoie F.B.*, Braidy N., and Gosselin R. (2015). Loglikelihood MCR for Low-Count Spectral Image Analysis. Conferentia Chemometrica. Budapest, Hungary
• Durao P.*, Gosselin R., Abatzoglou N., Guay JM. (2015). On-line Analysis of Multivitamin Powder Flows in a Tablet Press. IFPAC. Washington, United States of America
• Vachon-Lachance E., Abatzoglou N., Gosselin R., Cournoyer A., Simard J.S. (2015). Parametric Study of Potassium Chloride Caking Tendency using Cake Break Energy. CSChE. Edmonton, Canada
• Quinn P.*, Salvas J., Abatzoglou N., Gosselin R. (2015). Quantifying the Composition of Pharmaceutical Tablets using LIBS; the Importance of Matrix Effects. IFPAC. Washington, United States of America
• Abatzoglou N., Chaib O.* and Gosselin R. (2014). A PAT-based Experimental Methodology Relating Velocity Profiles in Flowing Powder Mixtures with Cohesion/Adhesion Parameters. IFPAC. Washington, United States of America
• Abatzoglou N., Chaib O.* and Gosselin R. (2014). A PAT-based Experimental Methodology Relating Velocity Profiles in Flowing Powder Mixtures with Cohesion/Adhesion Parameters. IFPAC. Washington, United States of America
• Chaib O., Gosselin R., Abatzoglou N. (2014). A methodology to Link Velocity Profiles of a Granulay System under Gravitational Flow with Cohesion/Adhesion Parameter. CSChE. Niagara Falls, Canada
• Lavoie FB*, Blais S, Braidy N., Gosselin R. (2014). Comparison of Principal Component Analysis and Multivariate Curve Resolution-Alternating Least Squares analysis of XPS spectral maps. Microscopy and Microanalysis. Hartford, United States of America
• Quinn P.*, Gosselin R., Abatzoglou N., Salvas J. and Simard J.S. (2014). Determining the Mineral Content of Pharmaceutical Multivitamin Tablets using LIBS. IFPAC. Washington, United States of America
• Gosselin R., Lavoie F.B.*, Braidy N. (2014). Improving XPS spectrum image segmentation using multivariate analysis with statistical calculations and basic image processing. CSChE. Niagara Falls, Canada
• Belley S., Abatzoglou N., Gosselin R., Perrier M., Lapointe-Garant P.P. and Simard J.S. (2014). In-line Monitoring and Control Systems Designed to Ensure the On-demand Supply of Pharmaceutical Tablet Coating Solutions Prepared by an Automated Process Unit. IFPAC. Baltimore, United States of America
• Durao P., Gosselin R., Abatzoglou N. and Guay J.M. (2014). Monitoring Multivitamin Powder Flows in a Tablet Press Using In-Line PAT tools. CSChE. Niagara Falls, Canada
• Vachon-Lachance E., Abatzoglou N., Gosselin R., Duchesne C. and Cournoyer A. (2014). Parametric Study of Dry Pharmaceutical Agglomeration during Blending. CSChE. Niagara Falls, Canada
• Abatzoglou N., Castellanos-Gil E.* and Gosselin R. (2013). A NIRS-based PAT Tool to Measure Radial and Axial Concentration Profiles in Processes Involving Flowing Powders: Prediction of Segregation Extent in Real Mixtures of Pharmaceutical Excipients. IFPAC. Baltimore, United States of America
• Gosselin R. (2013). Développements récents de technologies d’analyse de procédés en génie pharmaceutique. Rencontres Montpellier-Sherbrook. Montpellier, France
• Quinn P.*, Gosselin R., Abatzoglou N. and Salvas J. (2013). Mineral quantification in pharmaceutical multivitamin tablets using XRF and LIBS. CSChE. Fredericton, Canada
• Lavoie F.B.*, Braidy N. and Gosselin R. (2013). Multivariate XPS imaging: Improving Data Post-Processing. Materials Science and Technology (MS&T). Montreal, Canada
• Gosselin R., Abatzoglou N. and Castellanos-Gil E. (2013). Residence Time Distribution and Concentration Profiles in Processes Involving Flowing Powders: Evaluating Segregation in Pharmaceutical Formulations. 6th Pan-European QbD & PAT Conference (EuPAT),. Porto, Portugal
• Gosselin R. (2013). Retombées scientifiques, techniques et économiques de l’utilisation de PAT sur un procédé pharmaceutique. Seminar in Engineering, Health and Analysis (SEHA). Algiers, Algeria
• Castellanos-Gil E.*, Gosselin R., Abatzoglou N. (2012). A PAT/QbD Approach to Measure Radial and Axial Concentration Profiles in Flowing Powder Mixtures using NIRS Analysis : A Case Study with Industrial Hoppers of Different Geometries. CSChE. Vancouver, Canada
• Guay J.M.*, Lapointe-Garant P.P., Simard J.S., Gosselin R., Abatzoglou N. (2012). Capabilities and Limitations of In-line Multivariate LIF Analyzer for Powder Monitoring. IFPAC. Baltimore, United States of America
• Belley S., Abatzoglou N., Gosselin R., Lapointe-Garant P.P., Simard J.S., Perrier M. (2012). In-line Monitoring and Control Systems Designed to Ensure the Quality of Pharmaceutical Coating Solutions. CSChE. Vancouver, Canada
• Gosselin R., Lacombe M.O.*. (2012). Using Wavelet Texture Analysis to Determine Bulk Powder Particle Size. IFPAC. Baltimore, United States of America
• Abatzoglou N., Castellanos-Gil E., Gosselin R. (2011). Axial and Radial Composition Profiles in Flowing Particulate Mixtures. CSChE. London, Canada
• Yekpe K., Demers A.M., Simard J.S., Gosselin R., Abatzoglou N. (2011). Near Infrared Spectroscopy as a PAT Tool to Monitor in-line Pharmaceutical Powders in Fluid-bed Dryers. Stats and Control Meeting. Sherbrooke, Canada
• Yekpe K., Simard J.S., Gosselin R. and Abatzoglou N. (2009). Application du principe de la qualité par la conception pour le contrôle qualité en industrie pharmaceutique. ACFAS. Sherbrooke, Canada
• Guay J.M., Simard J.S., Gosselin R. and Abatzoglou N. (2009). Développement d’un spectrofluoromètre multivarié pour l’analyse de produits pharmaceutiques. ACFAS. Sherbrooke, Canada
• Gosselin R., Rodrigue D. and Duchesne C. (2009). Property Prediction of Wood/Plastic Composites through Spectral Imaging and Chemometrics Methods. 8th World Congress of Chemical Engineering. Montreal, Canada
• Gosselin R., Rodrigue D. and Duchesne C. (2009). Quality Control of Polymer Products through Spectral Imaging and Chemometrics Methods. ANTEC. Chicago, United States of America