Richard J. Wagner

Publications

Articles

• Alaa Huwaidi, Redha-Alla Abdo, François Lessard, Brigitte Guérin, Léon Sanche, J. Richard Wagner. (2026). Gold Nanoparticles Size Dependence on DNA Damage under X-rays. Chemical Research in Toxicology. DOI
• Ghizlane Loubane, Gabriel Robert, Syed Benazir Firdaus, Raphaël Robidas, Christian Comeau, Pierre-Luc Boudreault, Jeampy E. Komba, Hugo Gagnon, J Richard Wagner, Stephen Naylor, Klaus Klarskov. (2026). Structural characterization of a L-dehydroascorbic acid–L-homocysteine thiolactone reaction product: Intracellular formation in neuronal cells. Biochimica et Biophysica Acta (BBA) - General Subjects. DOI
• Jean Cadet, J. Richard Wagner. (2025). Pioneering contribution of Professor Bruce Ames to early development in biochemical aspects of oxidatively generated damage to DNA. Frontiers in Molecular Biosciences. DOI
• Gabriel Robert, J. Richard Wagner. (2025). Radical Oxidation of the 2-Deoxyribosyl Moiety of DNA: Characterization of Unique Strand Breaks with 5′-Carboxylate Termini. Journal of the American Chemical Society. DOI
• Gabriel Robert, Charlotte Sabourin, J. Richard Wagner. (2024). Oxidative Deformylation of the Predominant DNA Lesion 5-Formyl-2′-deoxyuridine. Chemical Research in Toxicology. DOI
• Jean Cadet, Dimitar Angelov, Paolo Di Mascio, J. Richard Wagner. (2024). Contribution of oxidation reactions to photo‐induced damage to cellular DNA. Photochemistry and Photobiology. DOI
• Alaa Huwaidi, Gabriel Robert, Bhavini Kumari, Andrew D. Bass, Pierre Cloutier, Brigitte Guérin, Léon Sanche, J. Richard Wagner. (2024). Electron-Induced Damage by UV Photolysis of DNA Attached to Gold Nanoparticles. Chemical Research in Toxicology. DOI
• Gabriel Robert, J Richard Wagner, Jean Cadet. (2023). Oxidatively generated tandem DNA modifications by pyrimidinyl and 2-deoxyribosyl peroxyl radicals. Free Radical Biology and Medicine. DOI
• Jean Cadet, Dimitar Angelov, J. Richard Wagner. (2022). Hydroxyl radical is predominantly involved in oxidatively generated base damage to cellular DNA exposed to ionizing radiation. International Journal of Radiation Biology. DOI
• Bhavini Kumari, Alaa Huwaidi, Gabriel Robert, Pierre Cloutier, Andrew D. Bass, Léon Sanche, J. Richard Wagner. (2022). Shape Resonances in DNA: Nucleobase Release, Reduction, and Dideoxynucleoside Products Induced by 1.3 to 2.3 eV Electrons. The Journal of Physical Chemistry B. DOI
• J. Richard Wagner, Paolo Di Mascio. (2022). Introduction to the Special Issue Dedicated to Jean Cadet†. Photochemistry and Photobiology. DOI
• Alaa Huwaidi, Bhavini Kumari, Gabriel Robert, Brigitte Guérin, Léon Sanche, J. Richard Wagner. (2021). Profiling DNA Damage Induced by the Irradiation of DNA with Gold Nanoparticles. The Journal of Physical Chemistry Letters. DOI
• J. Richard Wagner, Guru S. Madugundu, Jean Cadet. (2021). Ozone-Induced DNA Damage: A Pandora’s Box of Oxidatively Modified DNA Bases. Chemical Research in Toxicology. DOI
• Gabriel Robert, J. Richard Wagner. (2020). Tandem Lesions Arising from 5-(Uracilyl)methyl Peroxyl Radical Addition to Guanine: Product Analysis and Mechanistic Studies. Chemical Research in Toxicology. DOI
• Hugo Parent-Roberge, Adeline Fontvieille, René Maréchal, Richard Wagner, Tamàs Fülöp, Michel Pavic, Eléonor Riesco. (2020). Effects of combined exercise training on the inflammatory profile of older cancer patients treated with systemic therapy. Brain, Behavior, & Immunity - Health. DOI
• Jean Cadet, Paolo Di Mascio, J. Richard Wagner. (2019). (5′R)-and (5′S)-purine 5′,8-cyclo-2′-deoxyribonucleosides: reality or artifactual measurements? A reply to Chatgilialoglu’s comments (this issue). Free Radical Research. DOI
• Ghazal Khorsandgolchin, Léon Sanche, Pierre Cloutier, J. Richard Wagner. (2019). Strand Breaks Induced by Very Low Energy Electrons: Product Analysis and Mechanistic Insight into the Reaction with TpT. Journal of the American Chemical Society. DOI
• Jean Cadet, Paolo Di Mascio, J. Richard Wagner. (2019). Radiation-induced (5′R)-and (5′S)-purine 5′,8-cyclo-2′-deoxyribonucleosides in human cells: a revisited analysis of HPLC-MS/MS measurements. Free Radical Research. DOI
• Briedé, J.J., Deferme, L., Wolters, J.E.J., Claessen, S.M.H., van den Beucken, T., Wagner, R.J., van Breda, S.G., Kleinjans, J.C.S. (2018). A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases. Toxicology in Vitro. DOI
• Lemelin, V., Bass, A.D., Wagner, J.R., Sanche, L. (2017). Absolute vibrational excitation cross sections for 1-18 eV electron scattering from condensed dimethyl phosphate (DMP). Journal of Chemical Physics. DOI
• Cadet, J., Davies, K.J.A., Medeiros, M.H., Di Mascio, P., Wagner, J.R. (2017). Formation and repair of oxidatively generated damage in cellular DNA. Free Radical Biology and Medicine. DOI
• Choofong, S., Cloutier, P., Sanche, L., Wagner, J.R. (2016). Base Release and Modification in Solid-Phase DNA Exposed to Low-Energy Electrons. Radiation Research. DOI
• Deferme, L., Wolters, J.E.J., Claessen, S.M.H., Theunissen, D.H.J., Van Den Beucken, T., Wagner, J.R., Van Breda, S.G., Kleinjans, J.C.S., Briedé, J.J. (2016). Dynamic Interplay between the Transcriptome and Methylome in Response to Oxidative and Alkylating Stress. Chemical Research in Toxicology. DOI
• Ali, A., Wagner, J.R. (2016). Isomerization of 5-Hydroxy-5-methylhydantoin 2′-Deoxynucleoside into α-Furanose, β-Furanose, α-Pyranose, and β-Pyranose Anomers. Chemical Research in Toxicology. DOI
• Cadet, J., Wagner, J.R. (2016). Radiation-induced damage to cellular DNA: Chemical nature and mechanisms of lesion formation. Radiation Physics and Chemistry. DOI
• Behmand, B., Marignier, J.-L., Mostafavi, M., Wagner, J.R., Hunting, D.J., Sanche, L. (2015). Radiosensitization of DNA by Cisplatin Adducts Results from an Increase in the Rate Constant for the Reaction with Hydrated Electrons and Formation of Pt<sup>I</sup>. Journal of Physical Chemistry B. DOI
• Behmand, B., Wagner, J.R., Sanche, L., Hunting, D.J. (2014). Cisplatin intrastrand adducts sensitize DNA to base damage by hydrated electrons. Journal of Physical Chemistry B. DOI
• Madugundu, G.S., Cadet, J., Wagner, J.R. (2014). Hydroxyl-radical-induced oxidation of 5-methylcytosine in isolated and cellular DNA. Nucleic Acids Research. DOI
• Cadet, J., Wagner, J.R., Shafirovich, V., Geacintov, N.E. (2014). One-electron oxidation reactions of purine and pyrimidine bases in cellular DNA. International Journal of Radiation Biology. DOI
• Cadet, J., Wagner, J.R. (2014). Oxidatively generated base damage to cellular DNA by hydroxyl radical and one-electron oxidants: Similarities and differences. Archives of Biochemistry and Biophysics. DOI
• Cadet, J., Wagner, J.R. (2014). TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine. Mutation Research - Genetic Toxicology and Environmental Mutagenesis. DOI
• Alizadeh, E., Sanz, A.G., Madugundu, G.S., García, G., Wagner, J.R., Sanche, L. (2014). Thymidine decomposition induced by low-energy electrons and soft X rays under N<inf>2</inf> and O<inf>2</inf> atmospheres. Radiation Research. DOI
• Meesat, R., Belmouaddine, H., Allard, J.-F., Tanguay-Renaud, C., Lemay, R., Brastaviceanu, T., Tremblay, L., Paquette, B., Wagner, R.J., Jay-Gerin, J.-P., Lepage, M., Huels, M.A., Houde, D. (2013). Erratum: Cancer radiotherapy based on femtosecond IR laser-beam filamentation yielding ultra-high dose rates and zero entrance dose (Proceedings of the National Academy of Sciences of the United States of America (2012)109 (E2508-E2513) DOI: 10.1073/pnas.1116286109). Proceedings of the National Academy of Sciences of the United States of America. DOI
• González-Magaña, O., Tiemens, M., Reitsma, G., Boschman, L., Door, M., Bari, S., Lahaie, P.O., Wagner, J.R., Huels, M.A., Hoekstra, R., Schlathölter, T. (2013). Fragmentation of protonated oligonucleotides by energetic photons and Cq⁺ions. Physical Review A - Atomic, Molecular, and Optical Physics. DOI
• Madugundu, G.S., Wagner, J.R., Cadet, J., Kropachev, K., Yun, B.H., Geacintov, N.E., Shafirovich, V. (2013). Generation of guanine-thymine cross-links in human cells by one-electron oxidation mechanisms. Chemical Research in Toxicology. DOI
• Behmand, B., Cloutier, P., Girouard, S., Wagner, J.R., Sanche, L., Hunting, D.J. (2013). Hydrated electrons react with high specificity with cisplatin bound to single-stranded DNA. Journal of Physical Chemistry B. DOI
• Kay, P., Wagner, J.R., Gagnon, H., Day, R., Klarskov, K. (2013). Modification of peptide and protein cysteine thiol groups by conjugation with a degradation product of ascorbate. Chemical Research in Toxicology. DOI
• Paquette, B., Therriault, H., Wagner, J.R. (2013). Role of interleukin-1β in radiation-enhancement of MDA-MB-231 breast cancer cell invasion. Radiation Research. DOI
• Park, Y., Peoples, A.R., Madugundu, G.S., Sanche, L., Wagner, J.R. (2013). Side-by-side comparison of DNA damage induced by low-energy electrons and high-energy photons with solid TpTpT trinucleotide. Journal of Physical Chemistry B. DOI
• Meesat, R., Belmouaddine, H., Allard, J.-F., Tanguay-Renaud, C., Lemay, R., Brastaviceanu, T., Tremblay, L., Paquette, B., Wagner, J.R., Jay-Gerin, J.-P., Lepage, M., Huels, M.A., Houde, D. (2012). Cancer radiotherapy based on femtosecond IR laser-beam filamentation yielding ultra-high dose rates and zero entrance dose. Proceedings of the National Academy of Sciences of the United States of America. DOI
• Park, Y., Polska, K., Rak, J., Wagner, J.R., Sanche, L. (2012). Fundamental mechanisms of DNA radiosensitization: Damage induced by low-energy electrons in brominated oligonucleotide trimers. Journal of Physical Chemistry B. DOI
• Desmarais, G., Fortin, D., Bujold, R., Wagner, R., Mathieu, D., Paquette, B. (2012). Infiltration of glioma cells in brain parenchyma stimulated by radiation in the F98/Fischer rat model. International Journal of Radiation Biology. DOI
• Cadet, J., Douki, T., Ravanat, J.-L., Wagner, J.R. (2012). Measurement of oxidatively generated base damage to nucleic acids in cells: Facts and artifacts. Bioanalytical Reviews. DOI
• Samson-Thibault, F., Madugundu, G.S., Gao, S., Cadet, J., Wagner, J.R. (2012). Profiling cytosine oxidation in DNA by LC-MS/MS. Chemical Research in Toxicology. DOI
• Madugundu, G.S., Park, Y., Sanche, L., Wagner, J.R. (2012). Radiation-induced formation of 2',3'-dideoxyribonucleosides in DNA: A potential signature of low-energy electrons. Journal of the American Chemical Society. DOI
• Khalil, A., Gaudreau, P., Cherki, M., Wagner, R., Tessier, D.M., Fulop, T., Shatenstein, B. (2011). Antioxidant-rich food intakes and their association with blood total antioxidant status and vitamin C and E levels in community-dwelling seniors from the Quebec longitudinal study NuAge. Experimental Gerontology. DOI
• Park, Y., Li, Z., Cloutier, P., Sanche, L., Wagner, J.R. (2011). DNA damage induced by low-energy electrons: conversion of thymine to 5,6-dihydrothymine in the oligonucleotide trimer TpTpT. Radiation research. DOI
• Defoy, D., Dansette, P.M., Neugebauer, W., Wagner, J.R., Klarskov, K. (2011). Evaluation of deuterium labeled and unlabeled bis-methyl glutathione combined with nanoliquid chromatography-mass spectrometry to screen and characterize reactive drug metabolites. Chemical Research in Toxicology. DOI
• Li, Z., Cloutier, P., Sanche, L., Wagner, J.R. (2011). Low-energy electron-induced damage in a trinucleotide containing 5-bromouracil. Journal of Physical Chemistry B. DOI
• Paquette, B., Therriault, H., Desmarais, G., Wagner, R., Royer, R., Bujold, R. (2011). Radiation-enhancement of MDA-MB-231 breast cancer cell invasion prevented by a cyclooxygenase-2 inhibitor. British Journal of Cancer. DOI
• Regulus, P., Desilets, J.-F., Klarskov, K., Wagner, J.R. (2010). Characterization and detection in cells of a novel adduct derived from the conjugation of glutathione and dehydroascorbate. Free Radical Biology and Medicine. DOI
• Kuttappan-Nair, V., Samson-Thibault, F., Wagner, J.R. (2010). Generation of 2′-deoxyadenosine N⁶-aminyl radicals from the photolysis of phenylhydrazone derivatives. Chemical Research in Toxicology. DOI
• Li, Z., Cloutier, P., Sanche, L., Wagner, J.R. (2010). Low-energy electron-induced DNA damage: Effect of base sequence in oligonucleotide trimers. Journal of the American Chemical Society. DOI
• Wagner, J.R., Cadet, J. (2010). Oxidation reactions of cytosine DNA components by hydroxyl radical and one-electron oxidants in aerated aqueous solutions. Accounts of Chemical Research. DOI
• Cooke, M.S., Loft, S., Olinski, R., Evans, M.D., Bialkowski, K., Wagner, J.R., Dedon, P.C., Møller, P., Greenberg, M.M., Cadet, J. (2010). Recommendations for standardized description of and nomenclature concerning oxidatively damaged nucleobases in DNA. Chemical Research in Toxicology. DOI
• Dextraze, M.-E., Cecchini, S., Bergeron, F., Girouard, S., Turcotte, K., Wagner, J.R., Hunting, D.J. (2009). Reaching for the other side: Generating sequence-dependent interstrand cross-links with 5-bromodeoxyuridine and γ-rays. Biochemistry. DOI
• Tremblay, S., Wagner, J.R. (2008). Dehydration, deamination and enzymatic repair of cytosine glycols from oxidized poly(dG-dC) and poly(dI-dC). Nucleic Acids Research. DOI
• Li, Z., Zheng, Y., Cloutier, P., Sanche, L., Wagner, J.R. (2008). Low energy electron induced DNA damage: Effects of terminal phosphate and base moieties on the distribution of damage. Journal of the American Chemical Society. DOI
• Dextraze, M.-E., Wagner, J.R., Hunting, D.J. (2007). 5-Bromodeoxyuridine radiosensitization: Conformation-dependent DNA damage. Biochemistry. DOI
• Wishart, D.S., Tzur, D., Knox, C., Eisner, R., Guo, A.C., Young, N., Cheng, D., Jewell, K., Arndt, D., Sawhney, S., Fung, C., Nikolai, L., Lewis, M., Coutouly, M.-A., Forsythe, I., Tang, P., Shrivastava, S., Jeroncic, K., Stothard, P., ... Querengesser, L. (2007). HMDB: The human metabolome database. Nucleic Acids Research. DOI
• Slupsky, C.M., Rankin, K.N., Wagner, J., Fu, H., Chang, D., Weljie, A.M., Saude, E.J., Lix, B., Adamko, D.J., Shah, S., Greiner, R., Sykes, B.D., Marrie, T.J. (2007). Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles. Analytical Chemistry. DOI
• Bergeron, F., Klarskov, K., Hunting, D.J., Wagner, J.R. (2007). Near-UV photolysis of 2-methyl-1,4-naphthoquinone-DNA duplexes: Characterization of reversible and stable interstrand cross-links between quinone and adenine moieties. Chemical Research in Toxicology. DOI
• Sellami, L., Lacombe, S., Hunting, D., Wagner, R.J., Huels, M.A. (2007). Novel apparatus to measure hyperthermal heavy ion damage to DNA: Strand breaks, base loss, and fragmentation. Review of Scientific Instruments. DOI
• Gaudreau, P., Morais, J.A., Shatenstein, B., Gray-Donald, K., Khalil, A., Dionne, I., Ferland, G., Fülöp, T., Jacques, D., Kergoat, M.-J., Tessier, D., Wagner, R., Payette, H. (2007). Nutrition as a determinant of successful aging: Description of the Quebec longitudinal study NuAge and results from cross-sectional pilot studies. Rejuvenation Research. DOI
• Tremblay, S., Gantchev, T., Tremblay, L., Lavigne, P., Cadet, J., Wagner, J.R. (2007). Oxidation of 2′-deoxycytidine to four interconverting diastereomers of N¹carbamoyl-4,5-dihydroxy-2-oxoimidazolidine nucleosides. Journal of Organic Chemistry. DOI
• Rivière, J., Ravanat, J.-L., Wagner, J.R. (2006). Ascorbate and H<inf>2</inf>O<inf>2</inf>induced oxidative DNA damage in Jurkat cells. Free Radical Biology and Medicine. DOI
• Zheng, Y., Wagner, J.R., Sanche, L. (2006). DNA damage induced by low-energy electrons: Electron transfer and diffraction. Physical Review Letters. DOI
• Bergeron, F., Nair, V.K., Wagner, J.R. (2006). Near-UV induced interstrand cross-links in anthraquinone - DNA duplexes. Journal of the American Chemical Society. DOI
• Zheng, Y., Cloutier, P., Hunting, D.J., Wagner, J.R., Sanche, L. (2006). Phosphodiester and N-glycosidic bond cleavage in DNA induced by 4-15 eV electrons. Journal of Chemical Physics. DOI
• Vongsamphanh, R., Wagner, J.R., Ramotar, D. (2006). Saccharomyces cerevisiae Ogg1 prevents poly(GT) tract instability in the mitochondrial genome. DNA Repair. DOI
• Zheng, Y., Cloutier, P., Hunting, D.J., Sanche, L., Wagner, J.R. (2005). Chemical basis of DNA sugar-phosphate cleavage by low-energy electrons. Journal of the American Chemical Society. DOI
• Cecchini, S., Massen, C., La Madeleine, C., Huels, M.A., Sanche, L., Wagner, J.R., Hunting, D.J. (2005). Interstrand cross-link induction by UV radiation in bromodeoxyuridine- substituted DNA: Dependence on DNA conformation. Biochemistry. DOI
• Rivière, J., Klarskov, K., Wagner, J.R. (2005). Oxidation of 5-hydroxypyrimidine nucleosides to 5-hydroxyhydantoin and its α-hydroxy-ketone isomer. Chemical Research in Toxicology. DOI
• Sané, A.-T., Cantin, A.M., Paquette, B., Wagner, J.R. (2004). Ascorbate modulation of H2O2 and camptothecin-induced cell death in Jurkat cells. Cancer Chemotherapy and Pharmacology. DOI
• Bergeron, F., Houde, D., Hunting, D.J., Wagner, J.R. (2004). Electron transfer in DNA duplexes containing 2-methyl-1,4-naphthoquinone. Nucleic Acids Research. DOI
• Zheng, Y., Cloutier, P., Hunting, D.J., Wagner, J.R., Sanche, L. (2004). Glycosidic Bond Cleavage of Thymidine by Low-Energy Electrons. Journal of the American Chemical Society. DOI
• Zheng, Y., Cloutier, P., Wagner, J.R., Sanche, L. (2004). Irradiator to study damage induced to large nonvolatile molecules by low-energy electrons. Review of Scientific Instruments. DOI
• Rivière, J., Bergeron, F., Tremblay, S., Gasparutto, D., Cadet, J., Wagner, J.R. (2004). Oxidation of 5-hydroxy-2′-deoxyuridine into isodialuric acid, dialuric acid, and hydantoin products. Journal of the American Chemical Society. DOI
• Lenton, K.J., Sané, A.T., Therriault, H., Cantin, A.M., Payette, H., Wagner, J.R. (2003). Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency. American Journal of Clinical Nutrition.
• Lenton, K.J., Therriault, H., Cantin, A.M., Fülöp, T., Payette, H., Wagner, J.R. (2000). Direct correlation of glutathione and ascorbate and their dependence on age and season in human lymphocytes. American Journal of Clinical Nutrition.
• Paquette, B., Fortier, P.-K., Héroux, J., Thibodeau, P.A., Wagner, R., Liu, J., Cantin, A. (2000). Oestrogen metabolism in lymphangioleiomyomatosis: Catechol-O-methyltransferase pathway is not involved. Thorax. DOI
• Tremblay, S., Douki, T., Cadet, J., Wagner, J.R. (1999). 2'-Deoxycytidine glycols, a missing link in the free radical-mediated oxidation of DNA. Journal of Biological Chemistry. DOI
• Lenton, K.J., Therriault, H., Wagner, J.R. (1999). Analysis of glutathione and glutathione disulfide in whole cells and mitochondria by postcolumn derivatization high-performance liquid chromatography with ortho-phthalaldehyde. Analytical Biochemistry. DOI
• Lenton, K.J., Therriault, H., Fülöp, T., Payette, H., Wagner, J.R. (1999). Glutathione and ascorbate are negatively correlated with oxidative DNA damage in human lymphocytes. Carcinogenesis. DOI
• Wagner, J.R., Decarroz, C., Berger, M., Cadet, J. (1999). Hydroxyl-radical-induced decomposition of 2'-deoxycytidine in aerated aqueous solutions. Journal of the American Chemical Society. DOI
• Fülöp Jr., T., Wagner, J.R., Khalil, A., Weber, J., Trottier, L., Payette, H. (1999). Relationship between the response to influenza vaccination and the nutritional status in institutionalized elderly subjects. Journals of Gerontology - Series A Biological Sciences and Medical Sciences. DOI
• Khalil, A., Lehoux, J.-G., Wagner, R.J., Lesur, O., Cruz, S., Dupont, E., Jay-Gerin, J.-P., Wallach, J., Fülöp, T. (1998). Dehydroepiandrosterone protects low density lipoproteins against peroxidation by free radicals produced by γ-radiolysis of ethanol-water mixtures. Atherosclerosis. DOI
• Fülöp Jr., T., Fouquet, C., Allaire, P., Perrin, N., Lacombe, G., Stankova, J., Rola-Pleszczynski, M., Gagné, D., Wagner, J.R., Khalil, A., Dupuis, G. (1997). Changes in apoptosis of human polymorphonuclear granulocytes with aging. Mechanisms of Ageing and Development. DOI
• Khalil, A., Wagner, J.R., Fülöp Jr., T. (1997). Comparative study of the oxidation of low and high density lipoproteins exposed to gamma-irradiation. Journal de Chimie Physique et de Physico-Chimie Biologique. DOI
• Wagner, J.R., Tremblay, S., Gowans, B., Hunting, D.J. (1997). Incorporation of two deoxycytidine oxidation products into cellular DNA. Biochemistry and Cell Biology. DOI
• Fülöp, T., Lacombe, G., Wagner, R., Khalil, A. (1997). Influence of aging on the susceptibility of LDL to oxidation. FASEB Journal.
• Bardet, M., Cadet, J., Wagner, J.R. (1996). Conformational analysis of some radiation-induced decomposition products of thymidine using¹³C NMR analysis. Magnetic Resonance in Chemistry. DOI
• Wagner, J.R., Blount, B.C., Weinfeld, M. (1996). Excision of oxidative cytosine modifications from γ-irradiated DNA by Escherichia coll endonuclease III and human whole-cell extracts. Analytical Biochemistry. DOI
• Paquette, B., Wagner, R., Little, J.B. (1996). In vitro reversion of transformed phenotype in mouse C3H/10T1/2 cells: Modification in genomic 5-methylcytosine content. International Journal of Oncology.
• Khalil, A., Wagner, J.R., Lacombe, G., Dangoisse, V., Fülöp Jr., T. (1996). Increased susceptibility of low-density lipoprotein (LDL) to oxidation by γ-radiolysis with age. FEBS Letters. DOI
• Bienvenu, C., Wagner, J.R., Cadet, J. (1996). Photosensitized oxidation of 5-methyl-2'-deoxycytidine by 2-methyl-1,4-naphthoquinone: Characterization of 5-(hydroperoxymethyl)-2'-deoxycytidine and stable methyl group oxidation products. Journal of the American Chemical Society. DOI
• Buchko, G.W., Wagner, J.R., Cadet, J., Raoul, S., Weinfeld, M. (1995). Methylene blue-mediated photooxidation of 7,8-dihydro-8-oxo-2′-deoxyguanosine. BBA - Gene Structure and Expression. DOI
• Gantchev, T.G., Gowans, B.J., Hunting, D.J., Wagner, J.R., Van Lier, J.E. (1994). DNA strand scission and base release photosensitized by metallo-phthalocyanines. International Journal of Radiation Biology.
• Wagner, J.R., van Lier, J.E., Berger, M., Cadet, J. (1994). Thymidine Hydroperoxides: Structural Assignment, Conformational Features, and Thermal Decomposition in Water. Journal of the American Chemical Society. DOI
• Wagner, J.R., Van Lier, J.E., Berger, M., Cadet, J. (1994). Thymidine hydroperoxides: Structural assignment, conformational features, and thermal decomposition in water. Journal of the American Chemical Society.
• Wagner, J.R., Motchnik, P.A., Stocker, R., Sies, H., Ames, B.N. (1993). The oxidation of blood plasma and low density lipoprotein components by chemically generated singlet oxygen. Journal of Biological Chemistry.
• Wagner, J.R., Hu, C.-C., Ames, B.N. (1992). Endogenous oxidative damage of deoxycytidine in DNA. Proceedings of the National Academy of Sciences of the United States of America. DOI
• Wagner, J.R., Berger, M., Cadet, J., van Lier, J.E. (1990). Analysis of thymidine hydroperoxides by post-column reaction high-performance liquid chromatography. Journal of Chromatography A. DOI
• Wagner, J.R., Lier, J.E.v., JOHNSTON, L.J. (1990). QUINONE SENSITIZED ELECTRON TRANSFER PHOTOOXIDATION OF NUCLEIC ACIDS: CHEMISTRY OF THYMINE AND THYMIDINE RADICAL CATIONS IN AQUEOUS SOLUTION. Photochemistry and Photobiology. DOI
• Ali, H., Langlois, R., Wagner, J.R., Brasseur, N., Paquette, B., VAN Lier, J.E. (1988). BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES‐X. SYNTHESES AND ANALYSES OF SULFONATED PHTHALOCYANINES. Photochemistry and Photobiology. DOI
• Brasseur, N., Ali, H., Langlois, R., Wagner, J.R., Rousseau, J., Lier, J.E.v. (1987). BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES—V. PHOTODYNAMIC THERAPY OF EMT‐6 MAMMARY TUMORS IN MICE WITH SULFONATED PHTHALOCYANINES. Photochemistry and Photobiology. DOI
• Wagner, J.R., Ali, H., Langlois, R., Brasseur, N., VAN Ller, J.E. (1987). BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES—VI. PHOTOOXIDATION OF L‐TRYPTOPHAN BY SELECTIVELY SULFONATED GALLIUM PHTHALOCYANINES: SINGLET OXYGEN YIELDS AND EFFECT OF AGGREGATION. Photochemistry and Photobiology. DOI
• Krishna, C.M., Decarroz, C., Wagner, J.R., Cadet, J., Riesz, P. (1987). MENADIONE SENSITIZED PHOTOOXIDATION OF NUCLEIC ACID and PROTEIN CONSTITUENTS. AN ESR and SPIN‐TRAPPING STUDY. Photochemistry and Photobiology. DOI
• Wagner, J.R., van Lier, J.E., Decarroz, C., Cadet, J. (1987). Photo and radiation-induced formation of thymidine hydroperoxides. Bioelectrochemistry and Bioenergetics. DOI
• Decarroz, C., Wagner, J.R., Cadet, J. (1987). Specific deprotonation reactions of the pyrimidine radical cation resulting from the menadione mediated photosensitization of 2'deoxycytidine. Free Radical Research. DOI
• Langlots, R., Ali, H., Brasseur, N., Wagner, J.R., Lier, J.E.v. (1986). BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES—IV. TYPE II SENSITIZED PHOTOOXIDATION OF L‐TRYPTOPHAN AND CHOLESTEROL BY SULFONATED METALLO PHTHALOCYANINES. Photochemistry and Photobiology. DOI
• Cadet, J., Berger, M., Decarroz, C., Wagner, J.R., Van Lier, J.E., Ginot, Y.M., Vigny, P. (1986). Photosensitized reactions of nucleic acids. Biochimie. DOI
• Decarroz, C., Wagner, J.R., Van Lier, J.E., Krishna, C.M., Riesz, P., Cadet, J. (1986). Sensitized photo-oxidation of thymidine by 2-methyl-1,4-naphthoquinone. Characterization of the stable photoproducts. International Journal of Radiation Biology. DOI
• WAGNER, J.R., CADET, J., FISHER, G.J. (1984). PHOTO‐OXIDATION OF THYMINE SENSITIZED BY 2‐METHYL‐1,4‐NAPHTHOQUINONE: ANALYSIS OF PRODUCTS INCLUDING THREE NOVEL PHOTO‐DIMERS. Photochemistry and Photobiology. DOI

Livres

• Cadet, J., Wagner, J.R. (2015). Radiation-induced damage to cellular DNA: Recent aspects and perspectives. Biological Responses, Monitoring and Protection from Radiation Exposure.
• Cadet, J., Douki, T., Gasparutto, D., Ravanat, J.-L., Wagner, J.R. (2009). Chemical Reactions of the Radical Cations of Nucleobases in Isolated and Cellular DNA. Formation of Single-Base Lesions. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry. DOI
• Wagner, J.R., Van Lier, J.E., Decarroz, C., Berger, M., Cadet, J. (1990). Photodynarnic methods for oxy radical-induced DNA damage. Methods in Enzymology. DOI

Articles de conférence

• Meesat, R., Allard, J.-F., Belmouaddine, H., Brastaviceanu, T., Tremblay, L., Paquette, B., Jay-Gerin, J.-P., Wagner, J.R., Lepage, M., Houde, D. (2011). Filamentation of femtosecond laser pulses as a source for radiotherapy. Proceedings of SPIE - The International Society for Optical Engineering. DOI

Autres contributions

Cours enseignés ou supervisés à l'UdeS

• RBL747 - Aspects fondamentaux de la radiobiologie et de l'imagerie médicale. (2026). (1CR).
• RBL724 - Radicaux libres en biologie et médecine. (2023). (1CR).