Claire Dubois

Publications

Articles

• Cassidy Tomlinson, Ashwini Rajasekaran, Karine Brochu-Gaudreau, Claire Dubois, A. James Farmilo, Pavel Gris, Ariane Khatiz, Amanda Matthews, Marjo Piltonen, Abdelaziz Amrani, Denis Gris. (2024). A convenient analytic method for gel quantification using ImageJ paired with Python or R. PLOS ONE. DOI
• Mégane Lebel, Dominic O. Cliche, Martine Charbonneau, Karine Brochu-Gaudreau, Damien Adam, Emmanuelle Brochiero, Claire M. Dubois, André M. Cantin. (2024). Hypoxia Promotes Invadosome Formation by Lung Fibroblasts. Cells. DOI
• Martine Charbonneau, Kelly Harper, Karine Brochu-Gaudreau, Alexis Perreault, Laurent-Olivier Roy, Fabrice Lucien, Shulan Tian, David Fortin, Claire M Dubois. (2023). The development of a rapid patient-derived xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors. Neuro-Oncology. DOI
• María José Hurtado Gutiérrez, Frédérick L. Allard, Hugo Tshivuadi Mosha, Claire M. Dubois, Patrick P. McDonald. (2022). Human Neutrophils Generate Extracellular Vesicles That Modulate Their Functional Responses. Cells. DOI
• Mégane Lebel, Dominic O. Cliche, Martine Charbonneau, Damien Adam, Emmanuelle Brochiero, Claire M. Dubois, André M. Cantin. (2022). Invadosome Formation by Lung Fibroblasts in Idiopathic Pulmonary Fibrosis. International Journal of Molecular Sciences. DOI
• Martine Charbonneau, Kelly Harper, Karine Brochu-Gaudreau, Alexis Perreault, Patrick P. McDonald, Nadia Ekindi-Ndongo, Claudio Jeldres, Claire M. Dubois. (2022). Establishment of a ccRCC patient-derived chick chorioallantoic membrane model for drug testing. Frontiers in Medicine. DOI
• Perreault A, Harper K, Lebel M, Charbonneau M, Adam D, Brochiero E, Cantin AM, Leduc M, Gagnon L, Dubois CM. (2022). Human Lung Tissue Implanted on the Chick Chorioallantoic Membrane as a Novel <i>In Vivo</i> Model of Idiopathic Pulmonary Fibrosis. American journal of respiratory cell and molecular biology. DOI
• Karine Brochu-Gaudreau, Martine Charbonneau, Kelly Harper, Claire M. Dubois. (2022). Hypoxia Selectively Increases a SMAD3 Signaling Axis to Promote Cancer Cell Invasion. Cancers. DOI
• Maleck Kadiri, Martine Charbonneau, Catherine Lalanne, Kelly Harper, Frédéric Balg, Anthony Marotta, Claire M. Dubois. (2021). 14-3-3&eta; Promotes Invadosome Formation via the FOXO3&ndash;Snail Axis in Rheumatoid Arthritis Fibroblast-like Synoviocytes. International Journal of Molecular Sciences. DOI
• Kelly Harper, Anna Yatsyna, Martine Charbonneau, Karine Brochu-Gaudreau, Alexis Perreault, Claudio Jeldres, Patrick P. McDonald, Claire M. Dubois. (2021). The Chicken Chorioallantoic Membrane Tumor Assay as a Relevant In Vivo Model to Study the Impact of Hypoxia on Tumor Progression and Metastasis. Cancers. DOI
• Olga Tatsiy, Thomas Z. Mayer, Vanessa de Carvalho Oliveira, Stéphanie Sylvain-Prévost, Marilyn Isabel, Claire M. Dubois, Patrick P. McDonald. (2020). Cytokine Production and NET Formation by Monosodium Urate-Activated Human Neutrophils Involves Early and Late Events, and Requires Upstream TAK1 and Syk. Frontiers in Immunology. DOI
• Kelly Harper, Karine Brochu-Gaudreau, Caroline Saucier, Claire Dubois. (2019). Hypoxia Downregulates LPP3 and Promotes the Spatial Segregation of ATX and LPP1 During Cancer Cell Invasion. Cancers. DOI
• Annie Lauzier, Josiann Normandeau-Guimond, Vanessa Vaillancourt-Lavigueur, Vincent Boivin, Martine Charbonneau, Nathalie Rivard, Michelle S. Scott, Claire M. Dubois, Steve Jean. (2019). Colorectal cancer cells respond differentially to autophagy inhibition in vivo. Scientific Reports. DOI
• Kelly Harper, Roxane R. Lavoie, Martine Charbonneau, Karine Brochu-Gaudreau, Claire M. Dubois. (2018). The Hypoxic Tumor Microenvironment Promotes Invadopodia Formation and Metastasis through LPA1 Receptor and EGFR Cooperation. Molecular Cancer Research. DOI
• Héctor F. Araya, Hugo Sepulveda, Carlos O. Lizama, Oscar A. Vega, Sofia Jerez, Pedro F. Briceño, Roman Thaler, Scott M. Riester, Marcelo Antonelli, Flavio Salazar‐Onfray, Juan Pablo Rodríguez, Ricardo D. Moreno, Martin Montecino, Martine Charbonneau, Claire M. Dubois, Gary S. Stein, Andre J. van Wijnen, Mario A. Galindo. (2018). Expression of the ectodomain‐releasing protease ADAM17 is directly regulated by the osteosarcoma and bone‐related transcription factor RUNX2. Journal of Cellular Biochemistry. DOI
• Fabrice Lucien, Roxane R. Lavoie, Claire M. Dubois. (2018). Targeting endosomal pH for cancer chemotherapy. Molecular &amp; Cellular Oncology. DOI
• Julien Massonneau, Camille Ouellet, Fabrice Lucien, Claire M. Dubois, Jessica Tyler, Guylain Boissonneault. (2018). Suboptimal extracellular <scp>pH</scp> values alter <scp>DNA</scp> damage response to induced double‐strand breaks. FEBS Open Bio. DOI
• Fabrice Lucien, Pierre-Paul Pelletier, Roxane R. Lavoie, Jean-Michel Lacroix, Sébastien Roy, Jean-Luc Parent, Dominique Arsenault, Kelly Harper, Claire M. Dubois. (2017). Hypoxia-induced mobilization of NHE6 to the plasma membrane triggers endosome hyperacidification and chemoresistance. Nature Communications. DOI
• Martine Charbonneau, Roxane R Lavoie, Annie Lauzier, Kelly Harper, Patrick P McDonald, Claire M Dubois. (2016). Platelet-Derived Growth Factor Receptor Activation Promotes the Prodestructive Invadosome-Forming Phenotype of Synoviocytes from Patients with Rheumatoid Arthritis. The Journal of Immunology. DOI
• Lauzier A, Lavoie RR, Charbonneau M, Gouin-Boisvert B, Harper K, Dubois CM. (2015). Snail Is a Critical Mediator of Invadosome Formation and Joint Degradation in Arthritis. The American journal of pathology. DOI
• Stéphanie Sylvain-Prévost, Thornin Ear, François A Simard, Carl F Fortin, Claire M Dubois, Nicolas Flamand, Patrick P McDonald. (2015). Activation of TAK1 by Chemotactic and Growth Factors, and Its Impact on Human Neutrophil Signaling and Functional Responses. The Journal of Immunology. DOI
• Frédéric Trensz, Fabrice Lucien, Vanessa Couture, Thomas Söllrald, Geneviève Drouin, André-Jean Rouleau, Claire M. Dubois, Michel Grandbois, Gregory Lacraz, Guillaume Grenier. (2015). Erratum to: Increased microenvironment stiffness in damaged myofibers promotes myogenic progenitor cell proliferation. Skeletal Muscle. DOI
• Renzhong Li, Lalita Uttarwar, Bo Gao, Martine Charbonneau, Yixuan Shi, John S.D. Chan, Claire M. Dubois, Joan C. Krepinsky. (2015). High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells. Journal of Biological Chemistry. DOI
• Takashi Obama, Takehiko Takayanagi, Tomonori Kobayashi, Allison M. Bourne, Katherine J. Elliott, Martine Charbonneau, Claire M. Dubois, Satoru Eguchi. (2015). Vascular Induction of a Disintegrin and Metalloprotease 17 by Angiotensin II Through Hypoxia Inducible Factor 1α. American Journal of Hypertension. DOI
• Lucien F, Harper K, Pelletier PP, Volkov L, Dubois CM. (2014). Simultaneous pH measurement in endocytic and cytosolic compartments in living cells using confocal microscopy. Journal of visualized experiments : JoVE. DOI
• Thomas Z Mayer, François A Simard, Alexandre Cloutier, Harsh Vardhan, Claire M Dubois, Patrick P McDonald. (2013). The p38-MSK1 Signaling Cascade Influences Cytokine Production through CREB and C/EBP Factors in Human Neutrophils. The Journal of Immunology. DOI
• Dominique Arsenault, Karine Brochu-Gaudreau, Martine Charbonneau, Claire M. Dubois. (2013). HDAC6 Deacetylase Activity Is Required for Hypoxia-Induced Invadopodia Formation and Cell Invasion. PLoS ONE. DOI
• Annie Lauzier, Martine Charbonneau, Marilène Paquette, Kelly Harper, Claire M Dubois. (2012). Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis. Arthritis Research &amp; Therapy. DOI
• Dominique Arsenault, Fabrice Lucien, Claire M. Dubois. (2012). Hypoxia enhances cancer cell invasion through relocalization of the proprotein convertase furin from the <i>trans</i>‐golgi network to the cell surface. Journal of Cellular Physiology. DOI
• Fabrice Lucien, Karine Brochu-Gaudreau, Dominique Arsenault, Kelly Harper, Claire M. Dubois. (2011). Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK). PLoS ONE. DOI
• Lauzier A, Charbonneau M, Harper K, Jilaveanu-Pelmus M, Dubois CM. (2011). Formation of invadopodia-like structures by synovial cells promotes cartilage breakdown in collagen-induced arthritis: involvement of the protein tyrosine kinase Src. Arthritis and rheumatism. DOI
• Kelly Harper, Dominique Arsenault, Stephanie Boulay-Jean, Annie Lauzier, Fabrice Lucien, Claire M. Dubois. (2010). Autotaxin Promotes Cancer Invasion via the Lysophosphatidic Acid Receptor 4: Participation of the Cyclic AMP/EPAC/Rac1 Signaling Pathway in Invadopodia Formation. Cancer Research. DOI
• Alexandre Cloutier, Chantal Guindi, Pierre Larivée, Claire M. Dubois, Abdelaziz Amrani, Patrick P. McDonald. (2009). Inflammatory Cytokine Production by Human Neutrophils Involves C/EBP Transcription Factors. The Journal of Immunology. DOI
• Charles Thompson, Stéphanie McMahon, Ynuk Bossé, Claire M. Dubois, Jana Stankova, Marek Rola-Pleszczynski. (2008). Leukotriene D₄Up-Regulates Furin Expression through CysLT1 Receptor Signaling. American Journal of Respiratory Cell and Molecular Biology. DOI
• Martine Charbonneau, Kelly Harper, Francine Grondin, Manuela Pelmus, Patrick P. McDonald, Claire M. Dubois. (2007). Hypoxia-inducible Factor Mediates Hypoxic and Tumor Necrosis Factor α-induced Increases in Tumor Necrosis Factor-α Converting Enzyme/ADAM17 Expression by Synovial Cells. Journal of Biological Chemistry. DOI
• Philippe Guimont, Francine Grondin, Claire M. Dubois. (2007). Sox9-dependent transcriptional regulation of the proprotein convertase furin. American Journal of Physiology-Cell Physiology. DOI
• Alexandre Cloutier, Thornin Ear, Emilie Blais-Charron, Claire M Dubois, Patrick P McDonald. (2007). Differential involvement of NF-κB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils. Journal of Leukocyte Biology. DOI
• Stephanie McMahon, Martine Charbonneau, Sebastien Grandmont, Darren E. Richard, Claire M. Dubois. (2006). Transforming Growth Factor β1 Induces Hypoxia-inducible Factor-1 Stabilization through Selective Inhibition of PHD2 Expression. Journal of Biological Chemistry. DOI
• Guillaume Lansac, Weijia Dong, Claire M. Dubois, Nadia BenLarbi, Carlos Afonso, Isabelle Fournier, Michel Salzet, Robert Day. (2006). Lipopolysaccharide mediated regulation of neuroendocrine associated proprotein convertases and neuropeptide precursor processing in the rat spleen. Journal of Neuroimmunology. DOI
• Fernand-Pierre Gendron, Sébastien Mongrain, Patrick Laprise, Stéphanie McMahon, Claire M. Dubois, Mylène Blais, Claude Asselin, Nathalie Rivard. (2006). The CDX2 transcription factor regulates furin expression during intestinal epithelial cell differentiation. American Journal of Physiology-Gastrointestinal and Liver Physiology. DOI
• Julie Leblond, Marie-Hélène Laprise, Simon Gaudreau, Francine Grondin, Walter Kisiel, Claire Dubois. (2006). The serpin proteinase inhibitor 8: An endogenous furin inhibitor released from human platelets. Thrombosis and Haemostasis. DOI
• Stephanie McMahon, Francine Grondin, Patrick P. McDonald, Darren E. Richard, Claire M. Dubois. (2005). Hypoxia-enhanced Expression of the Proprotein Convertase Furin Is Mediated by Hypoxia-inducible Factor-1. Journal of Biological Chemistry. DOI
• Stephanie McMahon, Marie-Hélène Laprise, Claire M Dubois. (2003). Alternative pathway for the role of furin in tumor cell invasion processEnhanced MMP-2 levels through bioactive TGFβ. Experimental Cell Research. DOI
• Nadim Srour, Annie Lebel, Stephanie McMahon, Isabelle Fournier, Martin Fugère, Robert Day, Claire M Dubois. (2003). TACE/ADAM‐17 maturation and activation of sheddase activity require proprotein convertase activity. FEBS Letters. DOI
• Horst Posthaus, Claire M Dubois, Eliane Müller. (2003). Novel insights into cadherin processing by subtilisin‐like convertases. FEBS Letters. DOI
• Marie-Hélène Laprise, Francine Grondin, Pauline Cayer, Patrick P. McDonald, Claire M. Dubois. (2002). Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates. Blood. DOI

Chapitres de livre

• Stephen McManus, Walid Chababi, Dominique Arsenault, Claire M. Dubois, Caroline Saucier. (2018). Dissecting Oncogenic RTK Pathways in Colorectal Cancer Initiation and Progression. Methods in Molecular Biology. DOI

Autres contributions

Cours enseignés à l'UdeS

• IML703 - Cellules et molécules de l'inflammation. (2025-2026). (2CR).