A pilot randomized trial: The Effect of Local Prasterone Combined with Pelvic Muscle Floor Therapy on SUI in Women

Sommaire

DIRECTION DE RECHERCHE: Marie-Elisabeth Bouchard, Professeure - Département d'obstétrique-gynécologie
CODIRECTION DE RECHERCHE: Le Mai Tu, Professeure - Département de chirurgie
UNITÉ(S) ADMINISTRATIVE(S): Faculté de médecine et des sciences de la santé

CYCLE(S): 1er cycle
LIEU(X): Campus de la santé

Description du projet

Stress urinary incontinence is a highly prevalent condition in women that can have a great impact on their quality of life. Many pharmacological and surgical treatment options have been tried, but they are either invasive or not effective enough. The first line of treatment is conservative treatment, of which the most useful is pelvic floor muscle therapy (PFMT). Even though it is very effective if done appropriately, this treatment is time and resource consuming for both the patients and the healthcare system. The aim of this study is to potentialize the effect of PFMT using prasterone cream, which will hopefully decrease the necessary amount of PFMT performed to obtain the same benefits. Our study will include 40 premenopausal female patients that suffer from mild to moderate incontinence with a low serum testosterone levels. The main outcome measures will be age-related serum levels of total, free, and bioavailable testosterone, symptom assessment methods (pad test, voiding diary, patient reports) and imagery (3/4D US, dynamometer and elastography).

- recrutement des patientes pour le projet de recherche
- monter les questionnaires redcap
- effectuer l'analyse des données collectées
- écriture de l'article scientifique

MP837

Discipline(s) par secteur

Sciences de la santé

Obstétrique et gynécologie, Physiothérapie, Urologie

La dernière mise à jour a été faite le 6 février 2024. L’Université se réserve le droit de modifier ses projets sans préavis.