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Épisode 30 : Étude PEGeD

Diagnostic de l’embolie pulmonaire par les D-Dimères ajustés à la probabilité clinique (étude PEGeD)

Diffusé le 24 février 2020

Dans cette 30e baladodiffusion, les Drs Luc Lanthier et Geneviève LeTemplier discutent de diagnostic de l’embolie pulmonaire avec l’étude PEGeD, en plus de réviser la littérature médicale de décembre 2019 et janvier 2020.

Quiz clinique (3 min 25), article principal (3 min 53), critique (21 min 34), autres articles (27 min 10), réponse au quiz clinique (31 min 30)

Référence principale

Kearon C, de Wit K, Parpia S, Schulman S, Afilalo M, Hirsch A, et al. Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability. N Engl J Med. 2019;381(22):2125-34. PubMed PMID: 31774957.

Infographie

Article résumé

Lanthier L, LeTemplier G, Huard G, Plourde ME, Cauchon M. Chez les sujets ambulatoires avec embolie pulmonaire suspectée, une nouvelle stratégie diagnostique utilisant les D-dimères ajustés en fonction de la probabilité clinique permet-elle d’exclure de facon sécuritaire ce diagnostic sans avoir recours à l’imagerie?  Rev Med Interne. 2020;41(6):429-30. PubMed PMID: 32499058

Articles associés

Righini M, Van Es J, Den Exter PL, Roy PM, Verschuren F, Ghuysen A, et al. Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study. JAMA. 2014;311(11):1117-24. PubMed PMID: 24643601.

van der Hulle T, Cheung WY, Kooij S, Beenen LFM, van Bemmel T, van Es J, et al. Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study. Lancet. 2017;390(10091):289-97. PubMed PMID : 28549662.

Autres articles d'intérêt récents

Dransfield MT, Voelker H, Bhatt SP, Brenner K, Casaburi R, Come CE, et al. Metoprolol for the Prevention of Acute Exacerbations of COPD. N Engl J Med. 2019;381(24):2304-14. PubMed PMID : 31633896.

Voskoboinik A, Kalman JM, De Silva A, Nicholls T, Costello B, Nanayakkara S, et al. Alcohol abstinence in drinkers with atrial fibrillation. N Engl J Med. 2020;382(1):20‑8. PubMed PMID : 31893513.

Duceppe E, Patel A, Chan MTV, Berwanger O, Ackland G, Kavsak PA, et al. Preoperative n -terminal pro–b-type natriuretic peptide and cardiovascular events after noncardiac surgery: a cohort study. Ann Intern Med. 2020;172(2):96-104. PubMed PMID : 31869834.

Brown SGA, Ball EL, Perrin K, Asha SE, Braithwaite I, Egerton-Warburton D, et al. Conservative versus interventional treatment for spontaneous pneumothorax. N Engl J Med. 2020;382(5):405‑15. PubMed PMID : 31995686.

Kang D-H, Park S-J, Lee S-A, Lee S, Kim D-H, Kim H-K, et al. Early surgery or conservative care for asymptomatic aortic stenosis. N Engl J Med. 2020;382(2):111‑9. PubMed PMID : 31733181.

Amarenco P, Kim JS, Labreuche J, Charles H, Abtan J, Béjot Y, et al. A comparison of two LDL cholesterol targets after ischemic stroke. N Engl J Med. 2020;382(1):9‑19. PubMed PMID : 31738483.

Guides de pratique récents

Force USPST, Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, et al. Screening for Abdominal Aortic Aneurysm: US Preventive Services Task Force Recommendation Statement. JAMA. 2019;322(22):2211-8. PubMed PMID : 31821437.

Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2019;50(12):e344-e418. PubMed PMID : 31662037.

Summary of Revisions: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1):S4-S6. PubMed PMID : 31862743.

Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J. 2020;41(1):111-88. PubMed PMID : 31504418.

Crabb DW, Im GY, Szabo G, Mellinger JL, Lucey MR. Diagnosis and Treatment of Alcohol-Associated Liver Diseases: 2019 Practice Guidance From the American Association for the Study of Liver Diseases. Hepatology. 2020;71(1):306-33. PubMed PMID : 31314133.

Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J. 2020;41(4):543-603. PubMed PMID : 31504429.

Holguin F, Cardet JC, Chung KF, Diver S, Ferreira DS, Fitzpatrick A, et al. Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline. Eur Respir J. 2020;55(1). PubMed PMID : 31558662.

Morice AH, Millqvist E, Bieksiene K, Birring SS, Dicpinigaitis P, Domingo Ribas C, et al. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J. 2020;55(1). PubMed PMID : 31515408.

Ramos-Casals M, Brito-Zeron P, Bombardieri S, Bootsma H, De Vita S, Dorner T, et al. EULAR recommendations for the management of Sjogren's syndrome with topical and systemic therapies. Ann Rheum Dis. 2020;79(1):3-18. PubMed PMID : 31672775.

Richette P, Doherty M, Pascual E, Barskova V, Becce F, Castaneda J, et al. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann Rheum Dis. 2020;79(1):31-8. PubMed PMID : 31167758.

Hellmich B, Agueda A, Monti S, Buttgereit F, de Boysson H, Brouwer E, et al. 2018 Update of the EULAR recommendations for the management of large vessel vasculitis. Ann Rheum Dis. 2020;79(1):19-30. PubMed PMID : 31270110.

Ye Z, Reintam Blaser A, Lytvyn L, Wang Y, Guyatt GH, Mikita JS, et al. Gastrointestinal bleeding prophylaxis for critically ill patients: a clinical practice guideline. BMJ. 2020;368:l6722. PubMed PMID : 31907223.

Référence du quiz clinique

Meyer JA. Werner Forssmann and catheterization of the heart, 1929. Ann Thorac Surg. 1990;49(3):497‑9. PubMed PMID : 2178572.