BaladoCritique : Club de lecture médical est une baladodiffusion (podcast) francophone mensuelle qui analyse et commente les études récentes d’impact majeur en médecine interne. Ces articles sont sélectionnés par un groupe d’experts en lecture critique de l’Université de Sherbrooke et de l’Université Laval en fonction du potentiel de changement de pratique en médecine familiale/médecine interne. Nous espérons que cet outil facilitera le transfert de nouvelles connaissances médicales aux professionnels de la santé et améliorera ainsi votre pratique médicale.

Épisode 19 : Aspirine en prévention primaire (études ASCEND et ARRIVE)

Diffusé le 26 septembre 2018

Dans cette 19e baladodiffusion, les Drs Luc Lanthier et Danielle Pilon discutent d’aspirine en prévention primaire chez les sujets diabétiques et non diabétiques (études ASCEND et ARRIVE), en plus de réviser la littérature médicale de juillet at août 2018.

Quiz clinique (1 min 14), présentation 1e article (1 min 37), critique 1e article (18 min 40), présentation 2e article (21 min 45), critique 2e article (30 min 08), autres articles (40 min 40), réponse au quiz clinique (46 min 46)

Références principales

Group ASC. Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus. N Engl J Med. 2018. doi: 10.1056/NEJMoa1804988. PubMed PMID: 30146931.

Group ASC. Effects of n-3 Fatty Acid Supplements in Diabetes Mellitus. N Engl J Med. 2018. doi: 10.1056/NEJMoa1804989. PubMed PMID: 30146932.

Gaziano JM, Brotons C, Coppolecchia R, Cricelli C, Darius H, Gorelick PB, et al. Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial. Lancet. 2018. doi: 10.1016/s0140-6736(18)31924-x. PubMed PMID: 30158069.

McNeil JJ, Woods RL, Nelson MR, Reid CM, Kirpach B, Wolfe R, et al. Effect of Aspirin on Disability-free Survival in the Healthy Elderly. N Engl J Med. 2018. doi: 10.1056/NEJMoa1800722. PubMed PMID: 30221596.

McNeil JJ, Wolfe R, Woods RL, Tonkin AM, Donnan GA, Nelson MR, et al. Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. N Engl J Med. 2018. doi: 10.1056/NEJMoa1805819. PubMed PMID: 30221597.

Infographie

Articles associés

Antithrombotic Trialists' (ATT) Collaboration, Baigent C, Blackwell L, Collins R, Emberson J, Godwin J, Peto R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009 May 30;373(9678):1849-60. PubMed PMID: 19482214

De Berardis G, Sacco M, Strippoli GF, Pellegrini F, Graziano G, Tognoni G, et al. Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials. BMJ. 2009;339:b4531. PubMed PMID: 19897665.

Gregg EW, Cheng YJ, Srinivasan M, Lin J, Geiss LS, Albright AL, et al. Trends in cause-specific mortality among adults with and without diagnosed diabetes in the USA: an epidemiological analysis of linked national survey and vital statistics data. Lancet. 2018;391(10138):2430-40. PubMed PMID: 29784146.

Li L, Geraghty OC, Mehta Z, Rothwell PM. Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study. Lancet. 2017;390(10093):490-9. PubMed PMID: 28622955.

Rothwell PM, Cook NR, Gaziano JM, Price JF, Belch JFF, Roncaglioni MC, et al. Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials. Lancet. 2018;392(10145):387-99. PubMed PMID: 30017552.

Rawshani A, Rawshani A, Franzen S, Sattar N, Eliasson B, Svensson AM, et al. Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med. 2018;379(7):633-44. PubMed PMID: 30110583.

Yadlowsky S, Hayward RA, Sussman JB, McClelland RL, Min YI, Basu S. Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk. Ann Intern Med. 2018;169(1):20-9. PubMed PMID: 29868850.

Pylypchuk R, Wells S, Kerr A, Poppe K, Riddell T, Harwood M, et al. Cardiovascular disease risk prediction equations in 400 000 primary care patients in New Zealand: a derivation and validation study. Lancet. 2018;391(10133):1897-907. PubMed PMID: 29735391.

Manuel DG, Tuna M, Bennett C, Hennessy D, Rosella L, Sanmartin C, et al. Development and validation of a cardiovascular disease risk-prediction model using population health surveys: the Cardiovascular Disease Population Risk Tool (CVDPoRT). CMAJ. 2018;190(29):E871-E82. PubMed PMID: 30037888.

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Mente A, O'Donnell M, Rangarajan S, McQueen M, Dagenais G, Wielgosz A, et al. Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study. Lancet. 2018;392(10146):496-506. PubMed PMID: 30129465.

Thomalla G, Simonsen CZ, Boutitie F, Andersen G, Berthezene Y, Cheng B, et al. MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset. N Engl J Med. 2018;379(7):611-22. PubMed PMID: 29766770.

Guide de pratique récents

Shah H, Bilodeau M, Burak KW, Cooper C, Klein M, Ramji A, et al. The management of chronic hepatitis C: 2018 guideline update from the Canadian Association for the Study of the Liver. CMAJ. 2018;190(22):E677-E87. PubMed PMID: 29866893.

Référence du quiz clinique

Li Y, Pan A, Wang DD, Liu X, Dhana K, Franco OH, et al. Impact of Healthy Lifestyle Factors on Life Expectancies in the US Population. Circulation. 2018. PubMed PMID: 29712712.