Épisode 15 : Aspirine ou rivaroxaban comme thromboprophylaxie après une chirurgie orthopédique élective (étude EPCAT-II)

Diffusé le 26 mars 2018

Dans cette 15e baladodiffusion, le Dr Luc Lanthier discute de thromboprophylaxie après une chirurgie orthopédique de PTH ou PTG élective et de la place de l’aspirine par rapport au traitement standard à base d’anticoagulant, en plus de réviser la littérature médicale de février 2018.

Quiz clinique (0 min 55), présentation principale (1 min 20), critique (17 min 52), autres articles (22 min 32), réponse au quiz clinique (27 min 00)

Référence principale

Anderson DR, Dunbar M, Murnaghan J, Kahn SR, Gross P, Forsythe M, et al. Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty. N Engl J Med. 2018;378(8):699-707. PubMed PMID: 29466159.

Infographie

Articles associés

Falck-Ytter Y, Francis CW, Johanson NA, Curley C, Dahl OE, Schulman S, et al. Prevention of VTE in orthopedic surgery patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2 Suppl):e278S-e325S. PubMed PMID: 22315265.

 Anderson DR, Dunbar MJ, Bohm ER, et al. Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial. Ann Intern Med. 2013 Jun 4;158(11):800-6. PubMed PMID: 23732713

 The Pulmonary Embolism Prevention (PEP) Trial Collaborative Group. Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. Lancet 2000; 355: 1295-302. PubMed PMID: 10776741.

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Freund Y, Cachanado M, Aubry A, Orsini C, Raynal PA, Feral-Pierssens AL, et al. Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients: The PROPER Randomized Clinical Trial. JAMA. 2018;319(6):559-66. PubMed PMID: 29450523.

Gardner CD, Trepanowski JF, Del Gobbo LC, Hauser ME, Rigdon J, Ioannidis JPA, et al. Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial. JAMA. 2018;319(7):667-79. PubMed PMID: 29466592.

Graham MM, Sessler DI, Parlow JL, Biccard BM, Guyatt G, Leslie K, et al. Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery. Ann Intern Med. 2018;168(4):237-44. PubMed PMID: 29132159.

Shepstone L, Lenaghan E, Cooper C, Clarke S, Fong-Soe-Khioe R, Fordham R, et al. Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial. Lancet. 2018;391(10122):741-7. PubMed PMID: 29254858.

Référence du quiz clinique

Protocole d’immunisation du Québec (lien web)