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Simon Couillard

Professeur, Faculté de médecine et des sciences de la santé

FMSS Département de médecine

Présentation

Sujet de recherche

Asthme, Maladie pulmonaire obstructive chronique, Médiateurs immunologiques: cytokines et chimiokines, Signalisation cellulaire et maladies infectieuses et immunitaires

Disciplines de recherche

Immunologie, Pneumologie

Mots-clés

Asthme, Inflammation des voies aériennes, Modèles de prédiction clinique, Maladie pulmonaire obstructive chronique (MPOC)

Intérêts de recherche

Asthme de toute sévérité: biomarqueurs, phénotypes, médecine personnalisée - spécifiquement pour les problématiques cliniques rencontrées par les médecins de première ligne. Inflammation des voies aériennes: réponses épithéliales, éosinophiles. Modèles de prédiction clinique: modèles pronostics et prévention des crises d'asthme. Maladie pulmonaire obstructive chronique (MPOC) : biomarqueurs, phénotypes, traitements ciblés.

Centre de recherche

Centre de recherche du CHUS

Recherche clinique

Oui

Langues parlées et écrites

Anglais, Français

Diplômes

(2022). (Maîtrise avec mémoire, MSc). University of Oxford.

(2021). Severe asthma (Postdoctorat, Fellowship en recherche clinique). University of Oxford.

(2019). (Postdoctorat, Résidence). Université de Sherbrooke.

(2017). (Certificat, Microprogramme du 2e cycle). Université de Sherbrooke.

(2017). (Postdoctorat, Résidence). Université de Sherbrooke.

(2014). (Doctorat, MD). Université Laval.

Titres de compétence

Certificat de spécialiste (médecine interne) Specialist certificate (internal medicine). Collège des médecins du Québec.

Certificat de spécialiste (pneumologie) Specialist certificate (respirology). Collège des médecins du Québec.

FRCPC (médecine interne)(internal medicine). College Royal des Médecins et Chirurgiens du Canada.

FRCPC (pneumologie)(respirology). College Royal des Médecins et Chirurgiens du Canada.

Licentiate of the Medical Council of Canada. Conseil médical du Canada.

Expérience académique

Assistant-professor in medicine. (2022-). Université de Sherbrooke. Canada.

Clinical research fellow; Area: severe asthma. (2019-2021). University of Oxford. Royaume-Uni.

Médecin résident (médecine interne puis pneumologie). (2014-2019). Université de Sherbrooke. Canada.

Stages de recherche clinique sous la supervision des Docteurs Jean-Louis Aubé et Pierre Larivée - 2 x 4 semaines Sujet : syndrome de chevauchement asthme sévère & apnée obstructive du sommeil. (2017-2018). Université de Sherbrooke. Canada.

Stage de recherche clinique sous la supervision des Docteurs Pierre Larivée et Alain Vanasse - 4 semaines Sujet : prédicteurs d’une réadmission pour exacerbation aigue de MPOC. (2016-2016). Université de Sherbrooke. Canada.

Stage de recherche clinique sous la supervision du Dr Louis-Philippe Boulet - 6 mois Sujet : santé respiratoire de l’athlète. (2011-2011). Université Laval. Canada.

Prix et distinctions

  • (2012) Tableau d’honneur académique canadien (Étudiant-athlète avec >80% moyenne générale). Sport interuniversitaire canadien. (Citation).
  • 11e position (hommes), Coupe du monde FINA * 32 km de nage en eau libre - 7h51min. Traversée internationale du Lac Saint-Jean. (Distinction).
  • 2018 ATS Abstract Scholarship. American Thoracic Society. (Prix).
  • 2021 ATS Abstract Scholarship. American Thoracic Society. (Prix).
  • BTS winter meeting conference grant. British Thoracic Society. (Prix).
  • Bourse de finaliste national. Bourses Loran. (Prix).
  • Boursier local. Bourses d’Excellence du Millénaire. (Prix).
  • Graduated with Distinction from the University of Oxford MSc in Experimental and Translational Therapeutics. University of Oxford. (Distinction).
  • Meilleure qualité scientifique de l’exposé (Journée scientifique du département de médecine). Université de Sherbrooke. (Prix).
  • Mention Honorable. Harvard National Model UN (simulation des nations unies). (Honneur).
  • Reconnaissance de la FMRQ pour contribution remarquable au sein de ses instances. Fédération des médecins résidents du Québec (FMRQ). (Prix).
  • Reconnaissance de l’implication étudiante. Université Laval. (Citation).
  • Étudiant athlète & service communautaire Lauréat national (SIC) & provincial (RSEQ) Natation. Sport interuniversitaire canadien. (Prix).

Financement

  • Chaire de recherche. (Obtenu). Chercheur principal. Chaire de recherche en santé respiratoire de l’Association Pulmonaire du Québec (capitalised funds, interests for research). Association Pulmonaire du Québec. Chaire de recherche en santé respiratoire. 388 800 $. (2022-2027)
  • Subvention. (En cours d’évaluation). Chercheur principal. A clinical and translational research program for personalised prediction, prevention, and management of asthma. Fonds de recherche du Québec - Santé (FRQS). Starting grant for young clinician investigators - Junior 1. 60 000 $. (2023-2027)
  • Subvention. (Obtenu). Chercheur principal. Point-of-care phenotyping responses to systemic therapies in the management asthma (PRISMA): a microbiomic substudy. bioMérieux sa (France). Investigator-initiated research. 90 000 $. (2022-2024)
  • Subvention. (Obtenu). Chercheur principal. Diagnostic and translational values of point-of-care blood eosinophils and exhaled nitric oxide (FeNO) in people referred by primary care for suspected asthma: a pilot study. AstraZeneca Canada Inc.. Externally Sponsored Research. 152 000 $. (2022-2024)
  • Subvention. (Obtenu). Chercheur principal. Étude pilote DIVE: faisabilité, performance diagnostique et valeur mécanistique des éosinophiles sanguins et de l’oxyde nitrique expiré (FeNO) en situation d’asthme suspecté par la première ligne. Association Pulmonaire du Québec. Fonds de recherche de la FQSR. 40 000 $. (2022-2024)
  • Subvention. (Obtenu). Chercheur principal. Phenotyping Responses to Systemic Corticosteroids in the Management Asthma Attacks (PRISMA): Clinical and Translational Correlation to Type-2 Inflammatory Biomarkers. Sanofi. Pathways Global Innovation Grant. 208 000 $. (2022-2024)
  • Subvention. (Obtenu). Cocandidat. Impact de la stimulation du nerf vague sur la fonction respiratoire chez les asthmatiques. Quebec Respiratory Health Research Network. Projet intersectoriel. 30 000 $. (2023-2024)
  • Subvention. (Obtenu). Chercheur principal. Local startup funds. Centre de recherche du CHUS. Start-up funds. 110 000 $. (2022-2024)
  • Subvention. (Obtenu). Chercheur principal. Point-of-care precision medicine for airways disease. Fondation du CHUS (Sherbrooke, QC). Directed donation from AstraZeneca. 40 000 $. (2022-2023)
  • Subvention. (Obtenu). Chercheur principal. Point-of-care precision medicine for airways disease. Fondation du CHUS (Sherbrooke, QC). Directed donation from GlaxoSmithKline. 50 000 $. (2022-2023)
  • Subvention. (Obtenu). Chercheur principal. Quebec Respiratory Health Research Biobank -Sherbrooke site. Quebec Respiratory Health Research Network. Biobank funds. 60 000 $. (2022-2023)
  • Subvention. (Obtenu). Chercheur principal. Quebec Respiratory Health Research Network - Career Start-Up and Mentorship Program for Young Investigators 2022-23. Fonds de recherche du Québec - Santé (FRQS). Quebec Respiratory Health Research Network - Career Start-Up and Mentorship Program for Young Invest. 25 000 $. (2022-2023)
  • Bourse d’études. (Terminé). Chercheur principal. Scholarship for clinical research fellowship in asthma. Société des Médecins (Sherbrooke, QC). Support aux formations complémentaires. 150 000 $. (2019-2022)
  • Subvention. (Terminé). Chercheur principal. Type 2 Innovation Grant- Mechanisms of FeNO non-suppression. Sanofi. Type 2 Innovation Grant. 80 000 $. (2019-2021)

Publications

Articles de revue

  • Lugogo, N Mohan, A Akukthota, P Couillard, S Rhoads, S Wechsler, M E. (2023). Are We Ready for Asthma Remission as a Clinical Outcome?. Chest -- (--), --. (Révision demandée).
  • Couillard, S Ducharme, F Pavord, I. (2023). Clinically accessible biomarkers to assess the modifiable risk of asthma/wheezing attacks in toddlers. The Journal of Allergy and Clinical Immunology: In Practice (Article accepté).
  • Couillard, S Côté, A. (2023). Predicting on-biologic remission in asthma: insight from the airways. Chest (Article accepté).
  • Petousi, N Pavord, I Couillard, S. (2023). Type-2 airway inflammation as an identifiable and treatable cause of chronic obstructive pulmonary disease. The Lancet - -. (Article accepté).
  • Khalfaoui L; Symon FA; Couillard S; Hargadon B; Chaudhuri R; Bicknell S; Mansur AH; Shrimanker R; Hinks TSC: Pavord ID; Fowler S; Brown V; McGarvey LP; Heaney LG; Austin CD; Howarth PH; Arron JR; Bradding P. (2022). Airway remodelling rather than cellular infiltration characterises both type2 cytokine biomarker-high and -low severe asthma. Allergy 77 (10), 2974-2986. DOI. (Article publié).
  • Corrisingham I, Richardson R, Hinks TSC, Spencer S, Couillard S, Maynard-Paquette AC, Howell I, Thomassen D. (2022). Biologics for chronic severe asthma: a network meta-analysis. Cochrane Database of Systematic Reviews - (10), -. (Article publié).
  • Couillard S, Steyerberg EW, Beasley R, Pavord ID. (2022). Blood eosinophils, fractional exhaled nitric oxide, and the risk of asthma attacks in randomised controlled trials: protocol for a systemic review and control arm patient-level meta-analysis for clinical prediction modelling. BMJ Open 12 (4), e058215. DOI. (Article publié).
  • Couillard S; Laugerud A; Jabeen M; Ramakrishnan S; Melhorn J; Hinks TSC; Pavord ID. (2022). Derivation of a prototype asthma attack risk scale centred on blood eosinophils and exhaled nitric oxide. Thorax 77 (2), 199-202. DOI. (Article publié).
  • Couillard S Pavord ID. (2022). Fluticasone furoate: CAPTAIN of fluticasones in type-2 inflammatory asthma. Respirology 27 (3), 184-186. DOI. (Article publié).
  • Couillard, S. (2022). Le tezepelumab en asthme sévère. InfoRQESR Décembre 2022 (-), 3-10. (Article publié).
  • Couillard S; Shrimanker R; Lemaire-Paquette S; Hynes GM; Borg C; Connolly C; Thulborn S; Moran AM; Poole S; Morgan S; Powell T; Pavord ID; Hinks TSC. (2022). Longitudinal changes in sputum and blood inflammatory mediators during FeNO suppression testing. Thorax 77 (8), 933-938. DOI. (Article publié).
  • Couillard S, Do W, Beasley R, Hinks TSC, Pavord ID. (2022). Predicting the benefits of type-2 targeted anti-inflammatory treatment with the prototype OxfoRd Asthma attaCk risk scaLE (ORACLE). ERJ Open Research 8 (1), 00570. DOI. (Article publié).
  • Couillard S Pavord ID Heaney LG Petousi N Hinks TSC. (2022). Sub-stratification oftype-2 high airway disease for therapeutic decision-making: a ‘bomb’ (bloodeosinophils) meets ‘magnet’ (FeNO) framework. Respirology 27 (8), 573-477. DOI. (Article publié).
  • St-Germain O Lachapelle P Pavord ID Couillard S. (2022). Tackling ‘people remodelling’ in corticosteroid dependent asthma with type-2 targeting biologics and a formal corticosteroid weaning protocol. touchREVIEWS in Respiratory & Pulmonary Diseases 7 (2), 44-7. (Article publié).
  • Couillard, S. (2022). The alarmin(g) effect of interleukin-5 blockade on residual eosinophil function is of clinical consequence. European Respiratory Journal 60 (1), 2200597. DOI. (Article publié).
  • Couillard, S Petousi, N Smigiel, K Molfino, N. (2022). Towards a Predict and Prevent Approach in Obstructive Airways Diseases. Journal of Allergy and Clinical Immunology: In Practice - -. (Article publié).
  • Ramakrishnan S; Couillard S. (2021). Antibiotics for asthma attacks – masking uncertainty. European Respiratory Journal 58 (1), 00183. DOI. (Article publié).
  • Couillard S; Connolly C; Borg C; Pavord ID. (2021). Asthma in pregnancy: An update. Obstetric Medicine 14 (3), 135-144. DOI. (Article publié).
  • Couillard S; Shrimanker R; Chaudhuri R; Mansur AH; McGarvey LP; Heaney LG; Fowler SJ; Bradding P; Pavord ID; Hinks TSC. (2021). Fractional Exhaled Nonsuppression Identifies Corticosteroid-Resistant Type-2 Signaling in SevereAsthma. Am J Respir Crit Care Med 204 (6), 731-734. DOI. (Article publié).
  • Couillard S; Jackson DJ; Wechsler M; Pavord ID. (2021). How I do it. Work-up of severe asthma. Chest 160 (6), 2019-2029. DOI. (Article publié).
  • Turnbull CD Porter BML Evans SB Smith O Lardner R Hallifax R Bettinson HV Talbot NP Bafadhel M Rahman NM Petousi N Achaiah A Addala D Banka R Bedawi E Chapman S Danbury H Couillard S Douglas E Elder P Fries A Flight W Fraser E Hardinge M Hinks TSC Ho LP Hoyles R Melhorn J Moore A Nathwani V Nickol A Park J Patel S Pavord ID Saunders P Laurenson-Schafer H Roxburgh F Sundaralingam A Sykes A Tsakok M Wilson R Wrightson JM. (2021). Improved COVID-19 outcomes in a large non-invasive respiratory support cohort despite emergence of the alpha variant. BMJ Open Respiratory Research 8 (1), 001044. DOI. (Article publié).
  • Couillard S; Boulet LP; Lachapelle P. (2021). The controversial role of as-needed short-acting β2-agonist monotherapy in mild asthma: a short review of current guidelines. Can J of Resp Crit Care and Sleep Medicine 5 (5), 273-275. DOI. (Article publié).
  • Moran AM; Ramakrishnan S; Borg CA; Connolly CM; Couillard S; Mwasuku CM; Pavord ID; Hinks TSC; Lehtimaki L. (2020). Blood Eosinophil Depletion with Mepolizumab, Benralizumab and Prednisolone in Eosinophilic Asthma. Am J Respir Crit Care Med 202 (9), 1314-1316. DOI. (Article publié).
  • Vanasse A; Courteau J; Courteau M; Benigeri M; Chiu YM; Dufour I; Couillard S; Larivée P; Hudon C. (2020). Healthcare utilization after a first hospitalization for COPD: a new approach of State Sequence Analysis based on the '6W' multidimensional model of care trajectories. BMC Health Serv Res 20 (1), 177. DOI. (Article publié).
  • Moran AM; Ramakrishnan S; Borg CA; Connolly CM; Couillard S; Mwasuku CM; Pavord ID; Hinks TSC; Lehtimӓki L. (2020). Reply to Lipworth et al.: Don't Forget about Facilitatory Effects of Corticosteroids on β 2-Adrenoceptors in Acute Asthma. Am J Respir Crit Care Med 202 (12), 1743-1744. DOI. (Article publié).
  • Qing L; Larivée P; Courteau J; Couillard S; Poder TG; Carrier N; Bélanger M; Vanasse A. (2019). Greater eosinophil counts at first COPD hospitalization are associated with more readmissions and fewer deaths. Int J Chron Obstruct Pulmon Dis 2019 (14), 331-341. DOI. (Article publié).
  • Couillard S; Bélanger M; Bouchard N. (2019). Q fever presenting as miliary pneumonia: Case imagery and differential diagnosis. Can J of Resp Crit Care and Sleep Medicine 3 (3), 164-165. DOI. (Article publié).
  • Poder TG; Carrier N; Bélanger M; Couillard S; Courteau, J; Larivée, P; Vanasse A. (2018). Eosinophil counts in first COPD hospitalizations: a 1-year cost analysis in Quebec. Int J Chron Obstruct Pulmon Dis 8 (13), 3065-3076. DOI. (Article publié).
  • Bélanger M; Couillard S; Courteau J; Larivée P; Poder TG; Carrier N; Girard K; Vézina FA; Vanasse A. (2018). Eosinophil counts in first COPD hospitalizations: a comparison of health service utilization. Int J Chron Obstruct Pulmon Dis 2018 (13), 3045-3054. DOI. (Article publié).
  • Couillard S; Larivée P; Courteau J; Vanasse A. (2017). Eosinophils in COPD Exacerbations Are Associated With Increased Readmissions. Chest 151 (2), 366-373. DOI. (Article publié).
  • Vanasse A, Courteau J, Couillard S, Beauchesne MF, Larivée P. (2017). Predicting One-year Mortality After a “First” Hospitalization for Chronic Obstructive Pulmonary Disease: An Eight-Variable Assessment Score Tool. Journal of COPD 14 (5), 490-497. DOI. (Article publié).
  • Couillard S; Bougault V; Turmel J; Boulet LP. (2014). Perception of bronchoconstriction following methacholine and eucapnicvoluntary hyperpnea challenges in elite athletes. Chest 145 (4), 794-802. (Article publié).

Livres

  • Couillard, S Belzile, M Campagna, C Vézina, FA Laferrière-Langlois, P Sirois-Giguère, G. (2016). Résumé en vue du Juniorat. (1.2). Canada : Internal medicine residency program, Université de Sherbrooke. (Article publié).

Chapitres de livre

  • Couillard S; Pavord I. (2022). Biological Therapies for Asthma. Laurent, G J Shapiro, S D. Encyclopedia of Respiratory Medicine (2). Pays-Bas : Elsevier. DOI. (Article publié).

Articles de magazine

  • Couillard, S. (2022). La famille des biologiques approuvés en asthme sévère s’élargit avec l’autorisation du tezepelumab. Info-RQESR. (Décembre).
  • Selina Wellbelove. (2022). Targeting the ‘bomb’ or the ‘magnet’: a new therapeuticframework for asthma?. The Limbic Respiratory.

Rapports

  • Couillard S, Tanguay-Rioux X, Grandjean-Blanchet C, Dufour S, Labossière M, Ruel-Laliberté J. (2018). The Impact of Competence by Design (CBD): Report on semi-structured interviews conducted on the 2017-2018 cohort of R1s in anesthesiology and Otolaryngology/Head and Neck Surgery in Quebec. Fédération des médecins résidents du Québec. 80 p.

Articles de conférence

  • Reed, P Beauchesne, MF Lachapelle, P Larivée, P Couillard, S. (2023). A Rare Case of Congenital Defects in the Newborn of a Patient with Uncontrolled Asthma on Dual Omalizumab-Dupilumab Biological Therapy. American Thoracicy Society meeting. (Article accepté).
  • Fortin, A Gendron, R Lachapelle, P LeBlanc, L Roy, V Couillard, S. (2023). Blastomycosis and Multiple Concurrent Pulmonary Infections in a Benralizumab-Treated Asthmatic. American Thoracicy Society meeting. (Article accepté).
  • Diver S, Haldar K, Khalfaoui L, Symon FA, Couillard S, Hargadon B, Chaudhuri R, Bicknell S, Mansur AH, Shrimanker R, Hinks TSC, Pavord ID, Fowler SJ, Brown V, McGarvey LP, Heaney LG, Austin CD, Howarth PH, Arron JR, Choy DF, Bradding P. (2023). Relative abundance of Haemophilus as a component of the respiratory microbiome is not associated with airway epithelial MUC5AC staining. European Respiratory Society congress. (Article soumis).
  • Do W; Beasley R; Hinks TSC; Pavord ID; Couillard S. (2022). Development of a Prototype ORACLE Web-app to Predict Treatment Benefits of Type-2 Targeted Anti-inflammatory Treatment in Asthma. American Thoracic Society meeting. (Article publié).
  • Couillard S; Peterson S; Bengtson T; van den Berge M; Price D; Beasley R; Sadatsafavi M; Janson C; Belton L; Fageras M; Mullerova H; Pavord ID. (2022). Prototype ORACLE Score Validation in NOVELTY: Predicted versus Observed Asthma Exacerbation Rates. American Thoracic Society meeting. (Article publié).
  • Couillard, S; Peterson, S; Bengtsson, T; van den Berge, M; Price, D; Beasley, R; Sadatsafavi, M; Janson, C; Papi, Alberto; Belton, L; Fagerås, M; Müllerová, H; Pavord, I. (2022). Risk factors for corticosteroid- and antibiotic only-treated asthma attacks in the NOVELTY cohort. European Respiratory Society congress. (Article publié).
  • Couillard S; Laugerud A; Jabeen M; Ramakrishnan S; Melorn J; Hinks T; Pavord I. (2021). A proof-of-concept scale to predict asthma attacks: the OxfoRd Asthma attaCk risk scaLE (ORACLE). American Thoracic Society meeting. (Article publié).
  • Couillard S; Beasley R; Steyerberg EW; Pavord ID. (2021). Blood eosinophils, exhaled nitric oxide, and the risk of asthma attacks in randomised controlled trials: protocol for a systemic review and control arm patient-level meta-analysis for clinical prediction modelling. Journées Québécoises de Recherche en Santé Respiratoire. (Article publié).
  • Couillard S; Melhorn J; Singhania A; Horowitz D; Djukanovic C; Woelk CH; Hinks TSC. (2021). Correlation of eotaxin-3 gene expression and other IL-13-induced genes in patients with asthma. European Respiratory Society congress. (Article publié).
  • Couillard, S; Melhorn J; Singhania A; Horowitz D; Djukanovic R; Woelk CH; Hinks TSC. (2021). Correlation of eotaxin-3 gene expression and other IL-13-induced genes in patients with asthma. British Thoracic Society winter meeting. (Article publié).
  • Couillard S; Melhorn J; Singhania A; Horowitz D; Djukanovíc R; Woelk C; Hinks TSC. (2021). Correlation of eotaxin-3 gene expression and other IL-13-induced genes in patients with asthma. Journées Québécoises de Recherche en Santé Respiratoire. (Article publié).
  • Couillard S; Laugerud A; Jabeen M; Ramakrishnan R; Melhorn J; Hinks TSC; Pavord ID. (2021). Derivation of a prototype asthmaattack risk scale centred on blood eosinophils and exhaled nitric oxide. Journées Québécoises de Recherche en Santé Respiratoire. (Article publié).
  • Couillard S; Laugerud A; Jabeen M; Ramakrishnan S; Melhorn J; Hinks TSC: Pavord ID. (2021). Derivation of a prototype asthma attack risk scale centred on blood eosinophils and exhaled nitric oxide. British Thoracic Society winter meeting. (Article publié).
  • Couillard S; Shrimanker R; Hynes G; Connolly C: Hayman A; Thulborn S; Poole S; Chaudhuri R; Mansur AH; McGarvey LP; Heaney LG; Fowler SJ; Bradding P; Pavord I; Hinks TSC. (2021). FeNO non-suppression identifies corticosteroid-resistant type-2 signaling in severe asthma. British Thoracic Society winter meeting. (Article publié).
  • Couillard S; Shrimanker R; Hynes G; Connolly C; Haryman A; Thulborn S; Moran A; Poole S; Powell T; Chaudhuri R; Mansur AH; McGarvey LP; Heaney LG; Fowler S; Bradding P; Pavord ID; Hinks TSC. (2021). Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2 Signaling in Severe Asthma. Journées Québécoises de Recherche en Santé Respiratoire. (Article publié).
  • Couillard S; Do W; Beasley R; Laugerud A; Jabeen M; Ramakrishnan S; Melhorn J; Hinks TSC; Pavord ID. (2021). Predicting the benefits of type-2 targeted anti-inflammatory treatment with the prototype OxfoRd Asthma attaCk risk scaLE (ORACLE). Journées Québécoises de Recherche en Santé Respiratoire. (Article publié).
  • Couillard S; Shrimanker R; Hynes G; Borg C; Connolly C; Hayman A; Thulborn S; Moran A; Poole S; Powell T; Chaudhuri R; Mansur AH; McGarvey LP; Heaney LG; Fowler SJ; Bradding P; Pavord ID; Hinks TSC. (2021). Raised FeNO in optimally-treated severe asthma identifies persistent eosinophilic chemotactic pull towards the airway. European Respiratory Society congress. (Article publié).
  • Couillard S; Do W; Beasley R; Laugerud A; Jabeen M; Ramakrishnan S; Melhorn J; Hinks TSC; Pavord ID. (2021). To what extent does the prototype ORACLE scale predict treatment benefits? Predicted versus observed impact of anti-inflammatory treatments. British Thoracic Society winter meeting. (Article publié).
  • Oliver ME; Poole S; Borg C; Connolly C; Pavord ID; Hinks TSC; Couillard S. (2021). Utility of adherence checks in patients with severe asthma eligible for biologics: a single centreretrospective analysis. European Respiratory Society congress. (Article publié).
  • Oliver M.E.; Poole S; Borg C; Connolly C; Pavord ID; Hinks TSC: Couillard S. (2021). Utility of adherence checks in patients with severe asthma eligible for biologics: a single centre retrospective analysis. British Thoracic Society winter meeting. (Article publié).
  • Dupras-Boileaum C; Couillard S; Gaudette E; Poulin Y. (2020). A Case of Follicular Lymphoma Presenting as Severe Interstitial Pneumonia. American Thoracic Society meeting. (Article publié).
  • Couillard S; Shrimanker R; Hynes G; Borg C; Connolly C; Harman A; Poole S; Moran A; Powell T; Pavord I; Hinks T. (2020). Mechanisms of FeNO Non-Suppression in Severe Asthma: Analysis of Sputum Type 2 Cytokines and Chemokines. European Respiratory Society congress. (Article publié).
  • Bélanger M; Couillard S; Vézina FA; Girard K; Larivée P; Poder TG; Courteau J; Vanasse A. (2018). Blood Eosinophil levels in First Hospitalization for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Are Associated with Increased COPD-Related Readmissions. American Thoracic Society meeting. (Article publié).
  • Couillard S; Bélanger M; Courteau J; Larivée P; Vanasse A. (2018). Blood eosinophils, readmissions and healthcare costs in COPD: a retrospective analysis. AstraZeneca Scientific Summit – Respiratory medicine. (Article publié).
  • Couillard S; Bélanger M; Bouchard N. (2018). Miliary pneumonia asa novel radiological manifestation of Q fever. American Thoracic Society meeting. (Article publié).
  • Tanguay-Rioux X; Grandjean-Blanchet C; Dufour S; Labossière M; Ruel-Laliberté J; Couillard S. (2018). The Impact of Competency by Design. Canadian Conference on Medical Education. (Article publié).
  • Tanguay-Rioux X; Grandjean-Blanchet C; Dufour S; Labossière M; Ruel-Laliberté J; Couillard S. (2018). The Impact of Competency by Design. International Conference on Residency Education. (Article publié).

Autres contributions

Cours enseignés

  • Applied Respiratory Pathophysiology. (2020-02-10 à 2021-02-10).University of Oxford. Royaume-Uni. (3CR).

Activités de collaboration internationale

  • Co-investigator. Royaume-Uni. Biomarker-stratified asthma exacerbation rates in the NOVELTY prospective observational cohort.
  • Lead investigator. Royaume-Uni. Blood eosinophils, fractional exhaled nitric oxide, and the risk of asthma attacks in randomised controlled trials: systemic review and control arm patient-level meta-analysis for clinical prediction modelling.

Présentations

  • Couillard S, Pavord I. (2022). Blood eosinophils, FeNO, and the modifiable risk of asthma attacks. AstraZeneca National Speaker Tour. Calgary, Canada
  • Couillard, S Busse, W. (2022). Can a predict and prevent treatment strategy help achieve clinical remission for asthma?. European Respiratory Society (ERS) conference. Barcelona, Espagne
  • Couillard S. (2022). Longitudinal changes in sputum and blood inflammatory mediators during FeNO suppression testing. Canadian Respiratory Research Network meeting. Ottawa, Canada
  • Couillard S. (2022). L’asthme, précisément – le programme PRISMA. GESER (groupe de recherche de l'IUCPQ). Québec, Canada
  • Couillard S. (2022). L’asthme professionnel. Conférence aux résidents et pneumologues de Sherbrooke. Sherbrooke, Canada
  • Couillard S. (2022). Measuring eosinophilic airway inflammation. TADIS 2022: Treatable Traits Initiative. Royaume-Uni
  • Couillard S. (2022). Oxyde nitrique expiré (FeNO) 101. Réseau Québécois d’Éducation en Santé Respiratoire - webinaire. Canada
  • Couillard S Bhutani M Chan C Côté A Dorscheid D Ducharme F Nair, P. (2022). Post-ATS National Webinar. Post-ATS National Webinar. Canada
  • Couillard S. (2022). Prédire et prévenir le remodelage bronchique et humain en asthme. Webconférence québécoise. Canada
  • Couillard S. (2022). Revue sur les traitements de l'asthme sévère. Communauté de pratique en santé respiratoire du Réseau Québécois d’Éducation en Santé Respiratoire. Réseau Québécois d’Éducation en Santé Respiratoire - webinaire. Canada
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  • Couillard S. (2022). The OxfoRd Asthma attaCk risk scaLE (ORACLE) papers. Centre of Excellence in Treatable Traits Journal Club. Newcastle, Australie
  • Couillard S, Pavord I. (2022). Type-2 inflammation as a treatable trait. Treatable Trait Symposium. Helsinki, Finlande
  • Couillard S Ducharme F Côté A. (2022). Une mise-à-jour provinciale du congrès 2022 de l’American Thoracic Society (ATS) International Conference. Une mise-à-jour provinciale du congrès 2022 de l’American Thoracic Society (ATS) International Conference. Canada
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  • Couillard, S. (2022). Échec et réponse partielle à la biothérapie: comment gérer la 2e ligne de traitements. Congrès Québécois en Santé Respiratoire. Montréal, Canada
  • Couillard S. (2021). Blood eosinophils, FeNO, and the modifiable risk of asthma attacks. Grupo de Rasgos Tratables y Medicini de Precisión. Bogota, Colombie
  • Côté A, Couillard S. (2021). Débat sur l’utilisation des biomarqueurs dans la prise en charge de l’asthme sévère. Forum québécois d'échanges scientifiques en santé respiratoire. Sherbrooke, Canada
  • Couillard S. (2021). L’investigation de l’asthme sévère. Congrès annuel de l'APPQ. Sherbrooke, Canada
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  • Pavord I, Couillard S. (2019). Grand Rounds clinical case: aspirin exacerbated respiratory disease. Oxford Grand Rounds, Acute General Medicine. Sherbrooke, Royaume-Uni