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Karine Tremblay

Professeure, Faculté de médecine et des sciences de la santé
FMSS Département de pharmacologie-physiologie

Présentation

Expériences académiques

  • Assistant Professor. (2020-). Université de Sherbrooke. Sherbrooke, QC, Canada.

Publications

Articles

  • Sophie St-Amour, Laurence Tessier, Janie Harnois, Catherine Allard, Alexandre Lavoie, Philippe Caron, Luigi Bouchard, Patrice Perron, Karine Tremblay. (2025). PCK1 and SLC22A2 gene variants associated with response to metformin treatment in type 2 diabetes. PLOS ONE. DOI
  • William Bourumeau, Karine Tremblay, Guillaume Jourdan, Catherine Girard, Catherine Laprise. (2023). Bacterial Biomarkers of the Oropharyngeal and Oral Cavity during SARS-CoV-2 Infection. Microorganisms. DOI
  • Justine Benoit-Piau, Karine Tremblay, Alain Piché, Frédéric Dallaire, Mathieu Bélanger, Marc-André d’Entremont, Jean-Charles Pasquier, Martin Fortin, Catherine Bourque, Fanny Lapointe, Jean-François Betala-Belinga, Geneviève Petit, Guillaume Jourdan, Renata Bahous, Camilo Maya, Amira Benzina, Muhammad Faiyaz Hossain, Marie-Audrey Peel, Olivier Houle, ... Paul Farand. (2023). Long-Term Consequences of COVID-19 in Predominantly Immunonaive Patients: A Canadian Prospective Population-Based Study. Journal of Clinical Medicine. DOI
  • Ann-Lorie Gagnon, William Beauchesne, Laurence Tessier, Charles David, Djamal Berbiche, Alexandre Lavoie, Alban Michaud-Herbst, Karine Tremblay. (2021). Adalimumab, Infliximab, and Vedolizumab in Treatment of Ulcerative Colitis: A Long-Term Retrospective Study in a Tertiary Referral Center. Crohn's & Colitis 360. DOI
  • Ann-Lorie Gagnon, Alexandre Lavoie, Marie-Pier Frigon, Alban Michaud-Herbst, Karine Tremblay. (2020). A Drug-Induced Acute Pancreatitis Retrospective Study. Canadian Journal of Gastroenterology and Hepatology. DOI
  • (2020). Gene expression profiles of recurrent acute pancreatitis risk in patients with sustained chylomicronemia. Endocrine journal. DOI
  • Tremblay, K., Gaudet, D., Khoury, E., Brisson, D. (2020). Dissection of Clinical and Gene Expression Signatures of Familial versus Multifactorial Chylomicronemia. Journal of the Endocrine Society. DOI
  • Gagnon, A.-L., Frigon, M.-P., Tremblay, K. (2020). Hospitalizations for Acute and Chronic Pancreatitis in a French-Canadian Population. Pancreas. DOI
  • Marie-Pier Frigon, Marie-Ève Blackburn, Camélia Dubois-Bouchard, Ann-Lorie Gagnon, Suzie Tardif, Karine Tremblay. (2019). Pharmacogenetic Testing in Primary Care Practice: Opinions of Physicians, Pharmacists and Patients. Pharmacogenomics. DOI
  • Dron, J.S., Wang, J., Berberich, A.J., Iacocca, M.A., Cao, H., Yang, P., Knoll, J., Tremblay, K., Brisson, D., Netzer, C., Gouni-Berthold, I., Gaudet, D., Hegele, R.A. (2018). Large-scale deletions of the ABCA1 gene in patients with hypoalphalipoproteinemia. Journal of Lipid Research. DOI
  • Gaudet, D., Stroes, E.S., Méthot, J., Brisson, D., Tremblay, K., Bernelot Moens, S.J., Iotti, G., Rastelletti, I., Ardigo, D., Corzo, D., Meyer, C., Andersen, M., Ruszniewski, P., Deakin, M., Bruno, M.J. (2016). Long-term retrospective analysis of gene therapy with Alipogene Tiparvovec and its effect on lipoprotein lipase deficiency-induced pancreatitis. Human Gene Therapy. DOI
  • Gaudet, D., Alexander, V.J., Baker, B.F., Brisson, D., Tremblay, K., Singleton, W., Geary, R.S., Hughes, S.G., Viney, N.J., Graham, M.J., Crooke, R.M., Witztum, J.L., Brunzell, J.D., Kastelein, J.J.P. (2015). Antisense inhibition of apolipoprotein C-III in patients with hypertriglyceridemia. New England Journal of Medicine. DOI
  • Meyers, C.D., Tremblay, K., Amer, A., Chen, J., Jiang, L., Gaudet, D. (2015). Effect of the DGAT1 inhibitor pradigastat on triglyceride and apoB48 levels in patients with familial chylomicronemia syndrome. Lipids in Health and Disease. DOI
  • Tremblay, K., Dubois-Bouchard, C., Brisson, D., Gaudet, D. (2014). Association of CTRC and SPINK1 gene variants with recurrent hospitalizations for pancreatitis or acute abdominal pain in lipoprotein lipase deficiency. Frontiers in Genetics. DOI
  • Gaudet, D., Brisson, D., Tremblay, K., Alexander, V.J., Singleton, W., Hughes, S.G., Geary, R.S., Baker, B.F., Graham, M.J., Crooke, R.M., Witztum, J.L. (2014). Targeting APOC3 in the familial chylomicronemia syndrome. New England Journal of Medicine. DOI
  • Gaudet, D., Méthot, J., Déry, S., Brisson, D., Essiembre, C., Tremblay, G., Tremblay, K., De Wal, J., Twisk, J., Van Den Bulk, N., Sier-Ferreira, V., Van Deventer, S. (2013). Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPL S447X) gene therapy for lipoprotein lipase deficiency: An open-label trial. Gene Therapy. DOI
  • Gaudet, D., Signorovitch, J., Swallow, E., Fan, L., Tremblay, K., Brisson, D., Meyers, C., Gruenberger, J.-B. (2013). Medical resource use and costs associated with chylomicronemia. Journal of Medical Economics. DOI
  • Loucif, Y., Méthot, J., Tremblay, K., Brisson, D., Gaudet, D. (2011). Contribution of adiponectin to the cardiometabolic risk of postmenopausal women with loss-of-function lipoprotein lipase gene mutations. Menopause. DOI
  • Tremblay, K., Méthot, J., Brisson, D., Gaudet, D. (2011). Etiology and risk of lactescent plasma and severe hypertriglyceridemia. Journal of Clinical Lipidology. DOI
  • Brisson, D., Méthot, J., Tremblay, K., Tremblay, M., Perron, P., Gaudet, D. (2010). Comparison of the efficacy of fibrates on hypertriglyceridemic phenotypes with different genetic and clinical characteristics. Pharmacogenetics and Genomics. DOI
  • Gaudet, D., de Wal, J., Tremblay, K., Déry, S., van Deventer, S., Freidig, A., Brisson, D., Méthot, J. (2010). Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency. Atherosclerosis Supplements. DOI
  • Chamberland, A., Madore, A.-M., Tremblay, K., Laviolette, M., Laprise, C. (2009). A comparison of two sets of microarray experiments to define allergic asthma expression pattern. Experimental Lung Research. DOI
  • Tremblay, K., Laprise, C. (2009). Genetics of respiratory diseases: Example of cystic fibrosis and asthma,Génétique des maladies respiratoires : L'exemple de la fibrose kystique et de l'asthme. Revue des Maladies Respiratoires Actualites. DOI
  • Tremblay, K., Lemire, M., Potvin, C., Tremblay, A., Hunninghake, G.M., Raby, B.A., Hudson, T.J., Perez-Iratxeta, C., Andrade-Navarro, M.A., Laprise, C. (2008). Genes to diseases (G2D) computational method to identify asthma candidate genes. PLoS ONE. DOI
  • Tremblay, K., Daley, D., Chamberland, A., Lemire, M., Montpetit, A., Laviolette, M., Musk, A.W., James, A.L., Chan-Yeung, M., Becker, A., Kozyrskyj, A.L., Sandford, A.J., Hudson, T.J., Paré, P.D., Laprise, C. (2008). Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues. Journal of Allergy and Clinical Immunology. DOI
  • Madore, A.-M., Tremblay, K., Hudson, T.J., Laprise, C. (2008). Replication of an association between 17q21 SNPs and asthma in a French-Canadian familial collection. Human Genetics. DOI
  • Bégin, P., Tremblay, K., Daley, D., Lemire, M., Claveau, S., Salesse, C., Kacel, S., Montpetit, A., Becker, A., Chan-Yeung, M., Kozyrskyj, A.L., Hudson, T.J., Laprise, C. (2007). Association of urokinase-type plasminogen activator with asthma and atopy. American Journal of Respiratory and Critical Care Medicine. DOI
  • Tremblay, K., Lemire, M., Provost, V., Pastinen, T., Renaud, Y., Sandford, A.J., Laviolette, M., Hudson, T.J., Laprise, C. (2006). Association study between the CX3CR1 gene and asthma. Genes and Immunity. DOI

Autres contributions

Cours enseignés à l'UdeS

  • BIM503 - Pharmacogénétique et pharmacogénomique. (2025). (2CR).