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Fabienne Langlois

Professeure, Faculté de médecine et des sciences de la santé
FMSS Département de médecine

Présentation

Sujet de recherche

Désordres endocriniens

Disciplines de recherche

Endocrinologie

Mots-clés

Cushing, hypophyse

Intérêts de recherche

Je m'intéresse à mieux comprendre l'épidémiologie, les caractéristiques cliniques et l'évolution des tumeurs hypophysaires non-sécrétantes. Je souhaite participer à l'avancement des thérapies pour les tumeurs hypophysaires sécrétantes dont l'acromégalie et Maladie de Cushing. Je m'intéresse à mieux comprendre les caractéristiques pronostiques des tumeurs hypophysaires pour mieux intervenir et les prendre en charge. Je m'intéresse à l'impact du déficit en hormone de croissance et à son traitement.

Recherche clinique

Langues parlées et écrites

Anglais, Français

Diplômes

(2010). (Doctorat, M.D.). Université de Sherbrooke.

(). (Attaché de recherche, Fellowship). Oregon Health Sciences University.

Titres de compétence

Certification CITI (Collaborative Institutional Training Initiative) en recherche sur les sujets humains et conduite responsable de la recherche.

Formation avancée en échographie de la thyroïde.

Expérience académique

Professeur-chercheur régulier (rang adjoint) Faculté de médecine et des sciences de la santé. (2016-). Centre Hospitalier Univ. de Sherbrooke. Canada.

Professeur régulier (rang adjoint) Faculté de médecine et des sciences de la santé de l'Univ. de Sherbrooke. (2011-2016). Hôpital Charles Lemoyne. Canada.

Professeur d'enseignement clinique. (2010-2011). Université de Sherbrooke. Canada.

Prix et distinctions

  • 1er prix. Présentation CDA/CSEM Annual Conference, pour " Food behavior evaluated by the Three?Factor Eating Questionnaire and associations with lifestyle and ghrelin measurements in healthy young adults.". Canadian Society of Endocrinology and Metabolism. (Prix).
  • 1er prix pour une présentation affichée: Congrès international francophone de gériatrie et gérontologie. Quebec, pour "Male menopause and hypothyroism? Description of a syndrome of endocrine insufficiency in context of acute disease.". Congrès international francophone de gériatrie et gérontologie. (Prix).
  • Travel Grant pour la présentation affichée: Higher recurrence rates in silent somatotroph adenomas compared to silent gonadotroph adenomas - large single center experience. Internation Pituitary Society. (Prix).

Publications

Articles de revue

  • Varlamov EV, Langlois F, Vila G and Fleseriu M. (2021). Cardiovascular riskassessment, thromboembolism and infection prevention in Cushing's syndrome - apractical approach. Eur J Endocrinol EJE (20), 1309. (Article publié).
  • St-Jean M, Lim DST, Langlois F. (2021). Hypercoagulability inCushing's syndrome: From arterial to venous disease. Best Pract Res Clin Endocrinol Metab (Article accepté).
  • Langlois, F, Suarez GM and Fleseriu M. (2020). Updates in rare and not-so-rare complications ofacromegaly: focus on respiratory function and quality of life in acromegaly. F1000Research (9), 791. (Article publié).
  • Wagner J, Langlois F, Lim DST, McCartney S, Fleseriu M. (2019). Hypercoagulability and Risk of Venous ThromboembolicEvents in Endogenous Cushing's Syndrome: A Systematic Meta-Analysis. Front Endocrinol (9), 805. DOI. (Article publié).
  • Langlois F, Manea A, Lim DST, McCartney S, Yedinak CG, Cetas JS, Fleseriu M. (2018). High prevalence of adrenal insufficiency atdiagnosis and headache recovery in surgically resected Rathke's cleft cysts-alarge retrospective single center study. Endocrine 63 (3), 463-469. DOI. (Article publié).
  • Langlois F, Chu J, Fleseriu M. (2018). Pituitary-Directed Therapies for Cushing's Disease. Front Endocrinology (9), 164. DOI. (Article publié).
  • Langlois F, Lim DST, Yedinak CG, Cetas I, McCartney S, Cetas JS, Dogan A, and Fleseriu M. (2018). Predictors of Silent Corticotroph Adenoma Recurrence;a Large Retrospective Single Center Study and Systematic Literature Review. Pituitary 21 (1), 32-40. DOI. (Article publié).
  • Langlois F, Woltjer R, Cetas JS, and Fleseriu M. (2018). Silent Somatotroph Pituitary Adenomas: An Update. Pituitary 21 (2), 194-202. DOI. (Article publié).
  • Langlois F, Lim DST, Varlamov E, Yedinak CG, Cetas JS, McCartney S, Dogan A, Fleseriu M. (2017). Clinicalprofile of silent growth hormone pituitary adenomas; higher recurrence ratecompared to silent gonadotroph pituitary tumors, a large single centerexperience. Endocrine 58 (3), 528-534. DOI. (Article publié).
  • Langlois F, Moramarco J, He G, Carr BR. (2017). Falsely Elevated SteroidHormones in a post-menopausal Woman Due to Laboratory Interference. Journal of Endocrine Society 1 (8), 1062-1066. (Article publié).
  • Langlois F, Fleseriu M. (2017). Recent Progress in Medical therapy of pituitary tumors. Endocrinology and Metabolism 32 (2), 162-170. DOI. (Article publié).
  • Langlois F, Lim DST, Fleseriu, M. (2017). Update on Adrenal Insufficiency: diagnosis and management in pregnancy. Curr Opin Endocrinol Diabetes Obes 24 (3), 184-192. DOI. (Article publié).
  • Langlois F, Langlois MF, Carpentier A, Brown C, Lemieux S, Hivert MF. (2011). Ghrelin levels are associated with hunger as measuredby the Three‐Factor Eating Questionnaire in healthy young adults. Physiology and Behavior 104 (3), 373-377. DOI. (Article publié).
  • Massicotte MH, Langlois F, Baillargeon JP. (2010). Current procedures for managing polycystic ovarysyndrome. Expert rev. Obstet. Gynecol 5 (1), 77-91. (Article publié).
  • Bravo G, Dubois MR, Langlois F, Bernier J. (2004). Quebec physician’s knowledge and opinions regardingsubstitute authorizes for decisionally incapacitated older adults. IRB: Ethics and Human Research 26 (5), 12-17. (Article publié).

Chapitres de livre

  • Fabienne Langlois Maria Fleseriu. (2018). Adrenocortical Insufficiency. Conn’s Current Therapy (Article publié).
  • Fabienne Langlois Marie-Hélène Massicotte. (2018). Endocrinology. Luc Lanthier. Guide pratique de médecine interne (7). Canada : Formed. (Article publié).

Autres contributions

Présentations

  • Cetas JS, Fleseriu M. (2019). Significant Peri-tumoral Inflammation in Craniopharyngiomas Mimicking Hypophysitis: Two Case Reports. International Pituitary Society Meeting. New Orleans, États-Unis
  • Lim DST, Yedinak C, Cetas I, McCartney S, Dogan A, Fleseriu M. (2017). Higher preoperative ACTH and less cystic appearance on imaging can predict silent corticotroph adenomas (SCA) tumor recurrence; SCA clinical characteristics in a large retrospective single center study and literature review. Endocrine Society Meeting.
  • Varlamov E, Lim DST, Yedinak C, Cetas JS, Dogan A, Fleseriu M. (2017). Higher recurrence rates in silent somatotroph adenomas compared to silent gonadotroph adenomas - large single center experience. International Pituitary Society Meeting.
  • Varlamov E, Langlois F, Prola J, Kim JBS, Lim DST, Yedinak C, Cetas JS, Fleseriu M. (2017). Imaging, pathological and clinical characteristics of mixed GH/PRL-producing pituitary adenomas in patients with acromegaly: large single center experience. Endocrine Society Meeting.
  • Lim DST, Yedinak C, Williams J, Fleseriu M. (2017). Single-center experience of patients with acromegaly treated with long-acting pasireotide for at least 5 years. International Pituitary Society Meeting.
  • Lim DST, Yedinak C, Williams J, Cetas JS Fleseriu M. (2017). Treatment of patients with acromegaly and inadequate biochemical response or intolerance to first-generation somatostatin receptor ligands: a single-center experience. International Pituitary Society Meeting.
  • Lim DST, Varlamov E, Kim J BS, Yedinak C, Cetas JS, Fleseriu M. (2017). Weight gain in acromegaly patients after pituitary surgery is substantial, persists over time, and is independent of age, baseline BMI, and biochemical control – a large single center experience. Endocrine Society Meeting.
  • Tessier P, Rabia Y, Lamarre L. (2013). Pathologic correlation of thyroid biopsies at Charles Lemoyne Hospital. World Congress on Thyroid Cancer. Toronto, Canada
  • Delisle É, Grégoire PL, Bensaber BA. (2011). Système d’aide à la décision clinique interactif: les facteurs de réussite. Journées Francophones d'Informatique Médicale. Tunis, Tunisie
  • Hivert MF, Carpentier AC, Brown C, Langlois MF. (2010). Food behavior evaluated by the Three‐Factor Eating Questionnaire and associations with lifestyle and ghrelin measurements in healthy young adults. International Congress on Obesity. Stockholm, Suède
  • Langlois MF, Brown C, Carpentier A, Genest A, Hivert MF, Plourde C, Xhignesse M. (2009). Development and evaluation of the impact of the program profession MD. Scientific workshop of the CPSS.
  • Hivert MF, Carpentier AC, Brown C, Langlois MF. (2009). Food behavior evaluated by the Three‐Factor Eating Questionnaire and associations with lifestyle and ghrelin measurements in healthy young adults. 2009 CDA/CSEM Annual Conference. Montréal, Canada
  • Lacombe G. (2006). Male menopause and hypothyroism? Description of a syndrome of endocrine insufficiency in context of acute disease. Congrès international francophone de gériatrie et gérontologie. Québec, Canada