Sara Larivière
Professeure, Faculté de médecine et des sciences de la santé
FMSS Département des sciences de l’imagerie médicale et des radiations
Présentation
Sujets, disciplines ou intérêts de recherche
Epilepsy, Neuroimaging
Expériences académiques
- Assistant Professor. (2024-). Université de Sherbrooke. Sherbrooke, Quebec, Canada.
Publications
Articles
- Ariane Kek-Laflamme, Frederic L.W.V.J. Schaper, Kevin Whittingstall, Page B. Pennell, Geoffrey S. Young, Gad A. Marshall, Sara Larivière, Rani A. Sarkis. (2026). Brain Structural Changes and Cognitive-Clinical Profiles in Late-Onset Unexplained Epilepsy. Neurology. DOI
- Sara Larivière, Sami Obaid. (2025). What witnessing neurosurgery taught me about modeling the brain. Nature Methods. DOI
- Ella Sahlas, Tamir Avigdor, Alexander Ngo, Jessica Royer, Sara Lariviere, Judy Chen, Ke Xie, Yezhou Wang, Jack Lam, Raul Rodriguez-Cruces, Thaera Arafat, Raluca Pana, Andrea Bernasconi, Neda Bernasconi, Birgit Frauscher, Boris C. Bernhardt. (2025). Alterations in Cortical Microstructure, Morphology, and Intrinsic Local Function in Spiking Tissue in Patients With Focal Epilepsy. Neurology. DOI
- Ngo, A., Royer, J., Rodriguez-Cruces, R., Xie, K., Dekraker, J., Auer, H., Tavakol, S., Lam, J., Schrader, D.V., Dudley, R.W.R., Bernasconi, A., Bernasconi, N., Frauscher, B., Lariviere, S., Bernhardt, B.C. (2024). Associations of Cerebral Blood Flow Patterns with Gray and White Matter Structure in Patients with Temporal Lobe Epilepsy. Neurology. DOI
- Xie, K., Royer, J., Larivière, S., Rodriguez-Cruces, R., Frässle, S., Cabalo, D.G., Ngo, A., DeKraker, J., Auer, H., Tavakol, S., Weng, Y., Abdallah, C., Arafat, T., Horwood, L., Frauscher, B., Caciagli, L., Bernasconi, A., Bernasconi, N., Zhang, Z., ... Bernhardt, B.C. (2024). Atypical connectome topography and signal flow in temporal lobe epilepsy. Progress in Neurobiology. DOI
- Weber, C.F., Kebets, V., Benkarim, O., Lariviere, S., Wang, Y., Ngo, A., Jiang, H., Chai, X., Park, B.-Y., Milham, M.P., Di Martino, A., Valk, S., Hong, S.-J., Bernhardt, B.C. (2024). Contracted functional connectivity profiles in autism. Molecular Autism. DOI
- Besso, L., Larivière, S., Roes, M., Sanford, N., Percival, C., Damascelli, M., Momeni, A., Lavigne, K., Menon, M., Aleman, A., Ćurčić-Blake, B., Woodward, T.S. (2024). Hypoactivation of the language network during auditory imagery contributes to hallucinations in Schizophrenia. Psychiatry Research - Neuroimaging. DOI
- Zhang, Q., Li, J., He, Y., Yang, F., Xu, Q., Larivière, S., Bernhardt, B.C., Liao, W., Lu, G., Zhang, Z. (2023). Atypical functional connectivity hierarchy in Rolandic epilepsy. Communications Biology. DOI
- Xie, K., Royer, J., Lariviere, S., Rodriguez-Cruces, R., de Wael, R.V., Park, B.-Y., Auer, H., Tavakol, S., DeKraker, J., Abdallah, C., Caciagli, L., Bassett, D.S., Bernasconi, A., Bernasconi, N., Frauscher, B., Concha, L., Bernhardt, B.C. (2023). Atypical intrinsic neural timescales in temporal lobe epilepsy. Epilepsia. DOI
- Larivière, S., Bayrak, Ş., Vos de Wael, R., Benkarim, O., Herholz, P., Rodriguez-Cruces, R., Paquola, C., Hong, S.-J., Misic, B., Evans, A.C., Valk, S.L., Bernhardt, B.C. (2023). BrainStat: A toolbox for brain-wide statistics and multimodal feature associations. NeuroImage. DOI
- Bartolini, E., Caciagli, L., Larivière, S., Trimmel, K. (2023). Editorial: Advances in neuroimaging of epilepsy. Frontiers in Neurology. DOI
- Wang, Y., Royer, J., Park, B.-Y., Vos De Wael, R., Larivière, S., Tavakol, S., Rodriguez-Cruces, R., Paquola, C., Hong, S.-J., Margulies, D.S., Smallwood, J., Valk, S.L., Evans, A.C., Bernhardt, B.C. (2023). Long-range functional connections mirror and link microarchitectural and cognitive hierarchies in the human brain. Cerebral Cortex. DOI
- Walton, E., Bernardoni, F., Batury, V.-L., Bahnsen, K., Larivière, S., Abbate-Daga, G., Andres-Perpiña, S., Bang, L., Bischoff-Grethe, A., Brooks, S.J., Campbell, I.C., Cascino, G., Castro-Fornieles, J., Collantoni, E., D'Agata, F., Dahmen, B., Danner, U.N., Favaro, A., Feusner, J.D., ... Ehrlich, S. (2022). Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals With Anorexia Nervosa: A Coordinated Analysis by the ENIGMA Eating Disorders Working Group. Biological Psychiatry. DOI
- Hettwer, M.D., Larivière, S., Park, B.Y., van den Heuvel, O.A., Schmaal, L., Andreassen, O.A., Ching, C.R.K., Hoogman, M., Buitelaar, J., van Rooij, D., Veltman, D.J., Stein, D.J., Franke, B., van Erp, T.G.M., Jahanshad, N., Thompson, P.M., Thomopoulos, S.I., Bethlehem, R.A.I., Bernhardt, B.C., ... Valk, S.L. (2022). Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders. Nature Communications. DOI
- Kirschner, M., Hodzic-Santor, B., Antoniades, M., Nenadic, I., Kircher, T., Krug, A., Meller, T., Grotegerd, D., Fornito, A., Arnatkeviciute, A., Bellgrove, M.A., Tiego, J., Dannlowski, U., Koch, K., Hülsmann, C., Kugel, H., Enneking, V., Klug, M., Leehr, E.J., ... Modinos, G. (2022). Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study. Molecular Psychiatry. DOI
- Royer, J., Bernhardt, B.C., Larivière, S., Gleichgerrcht, E., Vorderwülbecke, B.J., Vulliémoz, S., Bonilha, L. (2022). Epilepsy and brain network hubs. Epilepsia. DOI
- Lopez, S.M., Aksman, L.M., Oxtoby, N.P., Vos, S.B., Rao, J., Kaestner, E., Alhusaini, S., Alvim, M., Bender, B., Bernasconi, A., Bernasconi, N., Bernhardt, B., Bonilha, L., Caciagli, L., Caldairou, B., Caligiuri, M.E., Calvet, A., Cendes, F., Concha, L., ... Thomas, R.H. (2022). Event-based modeling in temporal lobe epilepsy demonstrates progressive atrophy from cross-sectional data. Epilepsia. DOI
- Cruces, R.R., Royer, J., Herholz, P., Larivière, S., Vos de Wael, R., Paquola, C., Benkarim, O., Park, B.-Y., Degré-Pelletier, J., Nelson, M.C., DeKraker, J., Leppert, I.R., Tardif, C., Poline, J.-B., Concha, L., Bernhardt, B.C. (2022). Micapipe: A pipeline for multimodal neuroimaging and connectome analysis. NeuroImage. DOI
- Park, B.-Y., Kebets, V., Larivière, S., Hettwer, M.D., Paquola, C., van Rooij, D., Buitelaar, J., Franke, B., Hoogman, M., Schmaal, L., Veltman, D.J., van den Heuvel, O.A., Stein, D.J., Andreassen, O.A., Ching, C.R.K., Turner, J.A., van Erp, T.G.M., Evans, A.C., Dagher, A., ... Bernhardt, B.C. (2022). Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology. Communications Biology. DOI
- Larivière, S., Royer, J., Rodríguez-Cruces, R., Paquola, C., Caligiuri, M.E., Gambardella, A., Concha, L., Keller, S.S., Cendes, F., Yasuda, C.L., Bonilha, L., Gleichgerrcht, E., Focke, N.K., Domin, M., von Podewills, F., Langner, S., Rummel, C., Wiest, R., Martin, P., ... Bernhardt, B.C. (2022). Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression. Nature Communications. DOI
- Park, B.-Y., Larivière, S., Rodríguez-Cruces, R., Royer, J., Tavakol, S., Wang, Y., Caciagli, L., Caligiuri, M.E., Gambardella, A., Concha, L., Keller, S.S., Cendes, F., Alvim, M.K.M., Yasuda, C., Bonilha, L., Gleichgerrcht, E., Focke, N.K., Kreilkamp, B.A.K., Domin, M., ... Bernhardt, B.C. (2022). Topographic divergence of atypical cortical asymmetry and atrophy patterns in temporal lobe epilepsy. Brain. DOI
- (2021). A Structure-Function Substrate of Memory for Spatial Configurations in Medial and Lateral Temporal Cortices. Cerebral cortex (New York, N.Y. : 1991). DOI
- (2021). An expanding manifold in transmodal regions characterizes adolescent reconfiguration of structural connectome organization. eLife. DOI
- (2021). Artificial intelligence for classification of temporal lobe epilepsy with ROI-level MRI data: A worldwide ENIGMA-Epilepsy study. NeuroImage. Clinical. DOI
- (2021). Atypical neural topographies underpin dysfunctional pattern separation in temporal lobe epilepsy. Brain : a journal of neurology. DOI
- (2021). Connectivity alterations in autism reflect functional idiosyncrasy. Communications biology. DOI
- (2021). Connectome biomarkers of drug-resistant epilepsy. Epilepsia. DOI
- (2021). ILAE Neuroimaging Task Force Highlight: harnessing optimized imaging protocols for drug-resistant childhood epilepsy. Epileptic disorders : international epilepsy journal with videotape. DOI
- (2021). Signal diffusion along connectome gradients and inter-hub routing differentially contribute to dynamic human brain function. NeuroImage. DOI
- (2021). Structural Connectivity Gradients of the Temporal Lobe Serve as Multiscale Axes of Brain Organization and Cortical Evolution. Cerebral cortex (New York, N.Y. : 1991). DOI
- (2021). The ENIGMA Toolbox: multiscale neural contextualization of multisite neuroimaging datasets. Nature methods. DOI
- (2020). Convergence of cortical types and functional motifs in the human mesiotemporal lobe. eLife. DOI
- (2020). A multi-scale cortical wiring space links cellular architecture and functional dynamics in the human brain. PLoS biology. DOI
- (2020). BrainSpace: a toolbox for the analysis of macroscale gradients in neuroimaging and connectomics datasets. Communications biology. DOI
- (2020). Functional connectome contractions in temporal lobe epilepsy: Microstructural underpinnings and predictors of surgical outcome. Epilepsia. DOI
- (2020). Macroscale and microcircuit dissociation of focal and generalized human epilepsies. Communications biology. DOI
- (2020). Multiscale Structure-Function Gradients in the Neonatal Connectome. Cerebral cortex (New York, N.Y. : 1991). DOI
- (2020). Myeloarchitecture gradients in the human insula: Histological underpinnings and association to intrinsic functional connectivity. NeuroImage. DOI
- (2020). Network-based atrophy modeling in the common epilepsies: A worldwide ENIGMA study. Science advances. DOI
- (2020). The ENIGMA-Epilepsy working group: Mapping disease from large data sets. Human brain mapping. DOI
- (2019). Atypical functional connectome hierarchy in autism. Nature communications. DOI
- (2019). Community-informed connectomics of the thalamocortical system in generalized epilepsy. Neurology. DOI
- (2019). Functional and effective reorganization of the aging brain during unimanual and bimanual hand movements. Human brain mapping. DOI
- (2019). Microstructure-Informed Connectomics: Enriching Large-Scale Descriptions of Healthy and Diseased Brains. Brain connectivity. DOI
- (2019). Older adults exhibit a more pronounced modulation of beta oscillations when performing sustained and dynamic handgrips. NeuroImage. DOI
- (2019). Targeting age-related differences in brain and cognition with multimodal imaging and connectome topography profiling. Human brain mapping. DOI
- (2018). Anatomical and microstructural determinants of hippocampal subfield functional connectome embedding. Proceedings of the National Academy of Sciences of the United States of America. DOI
- (2018). Disrupted functional network integrity and flexibility after stroke: Relation to motor impairments. NeuroImage. Clinical. DOI
- (2018). Identification of Time-Varying Cortico-cortical and Cortico-Muscular Coherence during Motor Tasks with Multivariate Autoregressive Models. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. DOI
- (2017). Altered functional connectivity in brain networks underlying self-referential processing in delusions of reference in schizophrenia. Psychiatry research. Neuroimaging. DOI
Autres contributions
Cours enseignés à l'UdeS
- RBL501 - Études pharmacologiques en imagerie biomédicale et radiothérapie. (2025-2026). (2CR).
Divers
- Chen, J., Ngo, A., Rodríguez-Cruces, R., Royer, J., Caligiuri, M.E., Gambardella, A., Concha, L., Keller, S.S., Cendes, F., Yasuda, C.L., Alvim, M.K.M., Bonilha, L., Gleichgerrcht, E., Focke, N.K., Kreilkamp, B., Domin, M., von Podewils, F., Langner, S., Rummel, C., ... Bernhardt, B.C. (2024). A WORLDWIDE ENIGMA STUDY ON EPILEPSY-RELATED GRAY AND WHITE MATTER COMPROMISE ACROSS THE ADULT LIFESPAN. bioRxiv.
- Kirschner, M., Hodzic-Santor, B., Kennedy, L., Hansen, J.Y., Antoniades, M., Nenadić, I., Kircher, T., Krug, A., Meller, T., Dannlowski, U., Grotegerd, D., Flinkenflügel, K., Meinert, S., Borgers, T., Goltermann, J., Hahn, T., Böhnlein, J., Leehr, E.J., Barkhau, C., ... Modinos, G. (2024). Multiscale characterization of cortical signatures in positive and negative schizotypy: A worldwide ENIGMA study. medRxiv.
- Ngo, A., Royer, J., Rodríguez-Cruces, R., Xie, K., DeKraker, J., Auer, H., Tavakol, S., Lam, J., Schrader, D., Dudley, R.W.R., Bernasconi, A., Bernasconi, N., Frauscher, B., Larivière, S., Bernhardt, B.C. (2023). CEREBRAL PERFUSION ALTERATIONS IN TEMPORAL LOBE EPILEPSY: STRUCTURAL UNDERPINNINGS AND NETWORK DISRUPTIONS. bioRxiv.
- Georgiadis, F., Larivière, S., Glahn, D., Hong, L.E., Kochunov, P., Mowry, B., Loughland, C., Pantelis, C., Henskens, F.A., Green, M.J., Cairns, M.J., Michie, P.T., Rasser, P.E., Tooney, P., Scott, R.J., Catts, S., Schall, U., Carr, V., Quidé, Y., ... Kirschner, M. (2023). CONNECTOME ARCHITECTURE SHAPES LARGE-SCALE CORTICAL ALTERATIONS IN SCHIZOPHRENIA: A WORLDWIDE ENIGMA STUDY. bioRxiv.
- Larivière, S., Park, B.-Y., Royer, J., DeKraker, J., Ngo, A., Sahlas, E., Chen, J., Rodríguez-Cruces, R., Weng, Y., Frauscher, B., Liu, R., Wang, Z., Shafiei, G., Mišić, B., Bernasconi, A., Bernasconi, N., Fox, M.D., Zhang, Z., Bernhardt, B.C. (2023). Connectome reorganization associated with temporal lobe pathology and its surgical resection. medRxiv.
- de Wael, R.V., Bayrak, Ş., Benkarim, O., Herholz, P., Larivière, S., Rodriguez-Cruces, R., Paquola, C., Hong, S.-J., Misic, B., Evans, A.C., Valk, S.L., Bernhardt, B.C. (2022). BRAINSTAT: A TOOLBOX FOR BRAIN-WIDE STATISTICS AND NEUROSCIENTIFIC CONTEXTUALIZATION. bioRxiv.
- Hettwer, M.D., Larivière, S., Park, B.Y., van den Heuvel, O.A., Schmaal, L., Andreassen, O.A., Ching, C.R.K., Hoogman, M., Buitelaar, J., Veltman, D.J., Stein, D.J., Franke, B., van Erp, T.G.M., Jahanshad, N., Thompson, P.M., Thomopoulos, S.I., Bethlehem, R.A.I., Bernhardt, B.C., Eickhoff, S.B., Valk, S.L. (2022). COORDINATED CORTICAL THICKNESS ALTERATIONS ACROSS PSYCHIATRIC CONDITIONS: A TRANSDIAGNOSTIC ENIGMA STUDY. medRxiv.
- Royer, J., Larivière, S., Rodriguez-Cruces, R., Cabalo, D.G., Tavakol, S., Auer, H., Park, B.-Y., Paquola, C., Smallwood, J., Jefferies, E., Caciagli, L., Bernasconi, A., Bernasconi, N., Frauscher, B., Bernhardt, B.C. (2022). CORTICAL MICROSTRUCTURAL GRADIENTS CAPTURE MEMORY NETWORK REORGANIZATION IN TEMPORAL LOBE EPILEPSY. bioRxiv.
- (2021). A convergent structure-function substrate of cognitive imbalances in autism.
- (2021). An Open MRI Dataset for Multiscale Neuroscience.
- (2021). Cortical and Subcortical Neuroanatomical Signatures of Schizotypy in 3,004 Individuals Assessed in a Worldwide ENIGMA Study.
- Wang, Y., Royer, J., Park, B.-Y., Vos de Wael, R., Larivière, S., Tavakol, S., Rodriguez-Cruces, R., Paquola, C., Hong, S.-J., Margulies, D.S., Smallwood, J., Valk, S.L., Evans, A.C., Bernhardt, B.C. (2021). Long-range connections mirror and link microarchitectural and cognitive hierarchies in the human brain. bioRxiv.
- Park, B.-Y., Kebets, V., Larivière, S., Hettwer, M.D., Paquola, C., Rooij, D.V., Buitelaar, J., Franke, B., Hoogman, M., Schmaal, L., Veltman, D.J., Van Den, O., Stein, D.J., Andreassen, O.A., Ching, C.R.K., Turner, J., Van Erp, T.G.M., Evans, A.C., Dagher, A., ... Bernhardt, B.C. (2021). Multilevel neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology. bioRxiv.
- (2021). Multimodal connectome biomarkers of cognitive and affective dysfunction in the common epilepsies.
- Larivière, S., Royer, J., Rodríguez-Cruces, R., Caligiuri, M.E., Gambardella, A., Concha, L., Keller, S.S., Cendes, F., Yasuda, C.L., Bonilha, L., Gleichgerrcht, E., Focke, N.K., Domin, M., von Podewills, F., Langner, S., Rummel, C., Wiest, R., Martin, P., Kotikalapudi, R., ... Bernhardt, B.C. (2021). Structural network alterations in focal and generalized epilepsy follow axes of epilepsy risk gene expression: An ENIGMA study. bioRxiv.
- (2021). Topographic divergence of atypical cortical asymmetry and regional atrophy patterns in temporal lobe epilepsy: a worldwide enigma study.
- (2020). A cortical wiring space links cellular architecture, functional dynamics and hierarchies in humans.
- Park, B.-Y., Bethlehem, R.A.I., Paquola, C., Larivière, S., Cruces, R.R., Vos de Wael, R., Bullmore, E.T., Bernhardt, B.C., Dolan, R., Goodyer, I., Fonagy, P., Jones, P., Moutoussis, M., Hauser, T., Neufeld, S., Romero-Garcia, R., St Clair, M., Vértes, P., Whitaker, K., ... Chamberlain, S. (2020). An expanding manifold characterizes adolescent reconfigurations of structural connectome organization. bioRxiv.
- (2020). Convergence of cortical types and functional motifs in the mesiotemporal lobe.
- (2020). Functional idiosyncrasy has a shared topography with group-level connectivity alterations in autism.
- (2020). Human brain function during pattern separation follows hippocampal and neocortical connectivity gradients.
- (2020). Microstructural underpinnings and macroscale functional implications of temporal lobe connectivity gradients.
- (2020). Network-based atrophy modelling in the common epilepsies: a worldwide ENIGMA study.
- (2020). The ENIGMA Toolbox: Cross-disorder integration and multiscale neural contextualization of multisite neuroimaging datasets.
- (2019). Functional connectome contractions in temporal lobe epilepsy: microstructural underpinnings and associations to surgical outcome.
- (2019). Myeloarchitecture gradients in the human insula serve as blueprints for its diverse connectivity and function.
