Pascale B. Beauregard

Prix et distinctions

• (2024) Prix Tremplin. Université de Sherbrooke.

Financement

• Subvention. Évolution adaptative en laboratoire comme outil d’optimisation d’une souche bactérienne . Génome Québec (QC, Canada). 100 000 $. (2025-2027).
• Subvention. Interplay between plant growth-promoting rhizobacteria and plants in complex systems. NSERC (Ottawa, Canada). 245 000 $. (2025-2030).
  Numéro de subvention : RGPIN-2025-06096.
• Subvention. Exploring Plant-Microbe Interactions in the Rhizosphere: A Comparative Analysis of Conventional and Organic Agricultural Practices Toward Sustainable Agriculture. Université de Sherbrooke (Sherbrooke, Canada). Fonds Molson. 60 000 $. (2025-2027).
• Subvention. Modulation de la formation de biofilm bactérien par la présence d'autres microorganismes. Fonds de Recherche du Québec – Nature et Technologies (Montreal, Canada). 90 000 $. (2024-2027).
  Numéro de subvention : 359578. Voir plus
• Subvention. Bacterial consortia for increase nitrogen fixation in agricultural soil. Natural Sciences and Engineering Research Council (Ottawa, Canada). 20 000 $. (2023-2024).
  Numéro de subvention : 571800-2021. Voir plus
• Subvention. Microbiote et interactions des bactéries dans la rhizosphère du soya: élaboration de communautés synthétiques à partir de sols québécois. Fonds de Recherche du Québec – Nature et Technologies (Montreal, Canada). 150 000 $. (2023-2026).
  Numéro de subvention : 326368. Voir plus
• Subvention. Développement d’une bactérie synthétique pour lutter contre les infections persistantes à Gram-positif. Centre de Recherche du CHUS (Sherbrooke, Canada). 74 980 $. (2021-2022).
• Subvention. Determination and optimization of Bacillus subtilis traits required for its establishment, persistence and activities on plant roots. Natural Sciences and Engineering Research Council (Ottawa, Canada). 36 000 $. (2021-2022).
  Numéro de subvention : RGPIN-2020-07057. Voir plus
• Subvention. Acquisition of a Fluorescence and Chemiluminescence Imaging Platform. Natural Sciences and Engineering Research Council (Ottawa, Canada). 53 588 $. (2019-2020).
  Numéro de subvention : RTI-2020-00424. Voir plus
• Subvention. 69th Annual Conference of the Canadian Society of Microbiologists (CSM 2019) - One Health-related symposia. Canadian Institutes of Health Research (Ottawa, Canada). 10 000 $. (2018-2019).
  Numéro de subvention : 201809PCS. Voir plus
• Subvention. Acquisition of a triple quadrupole mass spectrometer. Natural Sciences and Engineering Research Council (Ottawa, Canada). 149 995 $. (2018-2019).
  Numéro de subvention : RTI-2019-00598. Voir plus
• Subvention. Étude des interactions entre molécules pariétales de plantes et bactéries de la rhizosphère. Fonds de Recherche du Québec – Nature et Technologies (Montreal, Canada). 30 000 $. (2018-2020).
  Numéro de subvention : 263966. Voir plus
• Subvention. Conjugaison chez les bactéries Gram-positives: impact du biofilm et création d'outils de modification génétique. Fonds de Recherche du Québec – Nature et Technologies (Montreal, Canada). 162 000 $. (2018-2021).
  Numéro de subvention : 253077. Voir plus
• Subvention. Automatic solid-phase extraction system for the study of small organic molecules in environmental and biological samples. Natural Sciences and Engineering Research Council (Ottawa, Canada). 137 787 $. (2017-2018).
  Numéro de subvention : RTI-2018-00809. Voir plus
• Subvention. Sporulation and germination of the biofungicide Bacillus subtilis on Echinacea and Lavandula plants in a horticulture production. Natural Sciences and Engineering Research Council (Ottawa, Canada). 25 000 $. (2017-2018).
  Numéro de subvention : 522757-2017. Voir plus
• Subvention. Dynamique et impact de la sporulation de Bacillus subtilis chez les plantes. Fonds de Recherche du Québec – Nature et Technologies (Montreal, Canada). 76 200 $. (2016-2018).
  Numéro de subvention : 197327. Voir plus
• Subvention. High throughput extraction platform for the analysis of organic compounds in solid and semi-solid matrices. Natural Sciences and Engineering Research Council (Ottawa, Canada). 127 900 $. (2016-2017).
  Numéro de subvention : RTI-2017-00353. Voir plus
• Subvention. Molecular requirements of Bacillus subtilis root colonization. Natural Sciences and Engineering Research Council (Ottawa, Canada). 210 000 $. (2014-2020).
  Numéro de subvention : RGPIN-2014-04628. Voir plus
• Subvention. Acquisition of a Fluorescence-Activated Cell Sorter (FACS). Natural Sciences and Engineering Research Council (Ottawa, Canada). 150 000 $. (2014-2015).
  Numéro de subvention : 472742-2015. Voir plus
• Subvention. Platform for molecular and chemical studies of interactions between plant roots and beneficial bacteria. Canada Foundation for Innovation (Ottawa, Canada). 120 000 $. (2014).
  Numéro de subvention : 32620. Voir plus
• Subvention. Étude de la formation de biofilms par B. subtilis sur les racines de la plante modèle A. thaliana. Fonds de Recherche du Québec – Nature et Technologies (Montreal, Canada). 60 000 $. (2009-2012).
  Numéro de subvention : 133260. Voir plus
• Subvention. Molecular and functional characterization of Ciflp, a potential prion protein implicated in cell viability in the absence of the essential chaperone calnexin. Natural Sciences and Engineering Research Council (Ottawa, Canada). 35 000 $. (2005-2006).
  Numéro de subvention : grant.2802396. Voir plus
• Subvention. Molecular and functional characterization of Ciflp, a potential prion protein implicated in cell viability in the absence of the essential chaperone calnexin. Natural Sciences and Engineering Research Council (Ottawa, Canada). 35 000 $. (2004-2005).
  Numéro de subvention : grant.2934317. Voir plus
• Subvention. PGSA. Natural Sciences and Engineering Research Council (Ottawa, Canada). 17 300 $. (2003-2004).
  Numéro de subvention : grant.2934180. Voir plus
• Subvention. PGSA. Natural Sciences and Engineering Research Council (Ottawa, Canada). 17 300 $. (2002-2003).
  Numéro de subvention : grant.2977080. Voir plus

Publications

Articles

• David Dumoulin, Mnar Ghrayeb, Sarah Côté, Daniel Garneau, Liraz Chai, Eric H. Frost, Tamàs Fülöp, Pascale B. Beauregard. (2026). Bidirectional relationship between the biofilm of Porphyromonas gingivalis and the amyloid-beta peptide. Microbiology Spectrum. DOI
• Taimeng Tan, Zhihui Xu, Lili Tao, Xinli Sun, Jiyu Xie, Youzhi Miao, Nan Zhang, Weibing Xun, Pascale B. Beauregard, Ákos T. Kovács, Yifa Yu, Yuan Luo, Wei Ran, Ruifu Zhang, Qirong Shen. (2025). Siderophore-mediated iron enrichment in the biofilm matrix enhances plant iron nutrition. Cell Reports. DOI
• Taimeng Tan, Lili Tao, Yuling Zhang, Pascale B. Beauregard, Xinli Sun, Youzhi Miao, Nan Zhang, Weibing Xun, Wei Ran, Baolei Jia, Ruifu Zhang, Qirong Shen, Zhihui Xu. (2025). The Volatile Pentadecane From Bacillus Alleviates Plant Iron Deficiency Through Activating the Reduction‐Based Fe Uptake System. Plant Biotechnology Journal. DOI
• Lili Tao, Xinli Sun, Pascale B. Beauregard, Taimeng Tan, Yuling Zhang, Jiyu Xie, Guidong Huang, Nan Zhang, Youzhi Miao, Qirong Shen, Zhihui Xu, Ruifu Zhang. (2025). Amino Acids From Root Exudates Induce Bacillus Spore Germination to Enhance Root Colonisation and Plant Growth Promotion. Microbial Biotechnology. DOI
• Corentin Bouvet, Pascale B. Beauregard, Céline Guéguen. (2025). Low-temperature biodegradation of freshwater dissolved organic matter during winter-to-spring transition. Frontiers in Environmental Science. DOI
• Julie Leroux, Pascale B. Beauregard, Jean-Philippe Bellenger. (2024). Azotobacter vinelandii N 2 fixation increases in co-culture with the PGPR Bacillus subtilis in a nitrogen concentration-dependent manner. Applied and Environmental Microbiology. DOI
• Clara Villeneuve, Pascale Beauregard, Robert L. Bradley. (2024). Non-native earthworms preferentially promote bacterial rather than fungal denitrification in northern temperate deciduous forests. Soil Biology and Biochemistry. DOI
• Vincent Charron‐Lamoureux, Sandrine Lebel‐Beaucage, Maude Pomerleau, Pascale B. Beauregard. (2024). Rooting for success: Evolutionary enhancement of Bacillus for superior plant colonization. Microbial Biotechnology. DOI
• Maude Pomerleau, Vincent Charron-Lamoureux, Lucille Léonard, Frédéric Grenier, Sébastien Rodrigue, Pascale B. Beauregard, Ákos T. Kovács, Yunrong Chai. (2024). Adaptive laboratory evolution reveals regulators involved in repressing biofilm development as key players in Bacillus subtilis root colonization. mSystems. DOI
• David Dumoulin, Tamas Fulop, Pascale B. Beauregard. (2023). The role of the biofilm of Porphyromonas gingivalis in driving amyloid beta secretion and aggregation. Alzheimer's & Dementia. DOI
• Vincent Charron-Lamoureux, Lounès Haroune, Maude Pomerleau, Léo Hall, Frédéric Orban, Julie Leroux, Adrien Rizzi, Jean-Sébastien Bourassa, Nicolas Fontaine, Élodie V. d’Astous, Philippe Dauphin-Ducharme, Claude Y. Legault, Jean-Philippe Bellenger, Pascale B. Beauregard. (2023). Pulcherriminic acid modulates iron availability and protects against oxidative stress during microbial interactions. Nature Communications. DOI
• Amanda Rosier, Maude Pomerleau, Pascale B. Beauregard, Deborah A. Samac, Harsh P. Bais. (2023). Surfactin and Spo0A-Dependent Antagonism by Bacillus subtilis Strain UD1022 against Medicago sativa Phytopathogens. Plants. DOI
• Louis Garneau, Pascale B. Beauregard, Sébastien Roy. (2023). Deciphering the role of non-Frankia nodular endophytes in alder through in vitro and genomic characterization. Canadian Journal of Microbiology. DOI
• Louis Garneau, Pascale B. Beauregard, Sébastien Roy. (2023). Neighbours in nodules: the interactions between Frankia sp. ACN10a and non-Frankia nodular endophytes of alder. Canadian Journal of Microbiology. DOI
• Paula A. Perea-Molina, Luz A. Pedraza-Herrera, Pascale B. Beauregard, Daniel Uribe-Vélez. (2022). A biocontrol Bacillus velezensis strain decreases pathogen Burkholderia glumae population and occupies a similar niche in rice plants. Biological Control. DOI
• Jean-Sébastien Bourassa, Gabriel Jeannotte, Sandrine Lebel-Beaucage, Pascale B. Beauregard. (2022). Second-Generation Transfer Mediates Efficient Propagation of ICE Bs1 in Biofilms. Journal of Bacteriology. DOI
• Martin Gélinas, Léa Museau, Arielle Milot, Pascale B. Beauregard. (2021). The de novo Purine Biosynthesis Pathway Is the Only Commonly Regulated Cellular Pathway during Biofilm Formation in TSB-Based Medium in Staphylococcus aureus and Enterococcus faecalis. Microbiology Spectrum. DOI
• Usma Munawara, Michael Catanzaro, Weili Xu, Crystal Tan, Katsuiku Hirokawa, Nabil Bosco, David Dumoulin, Abdelouahed Khalil, Anis Larbi, Simon Lévesque, Charles Ramassamy, Annelise E. Barron, Stephen Cunnane, Pascale B. Beauregard, Jean-Pierre Bellenger, Serafim Rodrigues, Mathieu Desroches, Jacek M. Witkowski, Benoit Laurent, ... Tamas Fulop. (2021). Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease. Immunity & Ageing. DOI
• Tamas Fulop, Shreyansh Tripathi, Serafim Rodrigues, Mathieu Desroches, Ton Bunt, Arnold Eiser, Francois Bernier, Pascale B Beauregard, Annelise E Barron, Abdelouahed Khalil, Adam Plotka, Katsuiku Hirokawa, Anis Larbi, Christian Bocti, Benoit Laurent, Eric H Frost, Jacek M Witkowski. (2021). Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer’s Disease. Neuropsychiatric Disease and Treatment. DOI
• Amanda Rosier, Pascale B. Beauregard, Harsh P. Bais. (2021). Quorum Quenching Activity of the PGPR Bacillus subtilis UD1022 Alters Nodulation Efficiency of Sinorhizobium meliloti on Medicago truncatula. Frontiers in Microbiology. DOI
• Maude Thérien, Heiko T. Kiesewalter, Emile Auria, Vincent Charron-Lamoureux, Mario Wibowo, Gergely Maróti, Ákos T. Kovács, Pascale B. Beauregard. (2020). Surfactin production is not essential for pellicle and root-associated biofilm development of Bacillus subtilis. Biofilm. DOI
• Vincent Charron-Lamoureux, Maude Thérien, Assena Konk, Pascale B. Beauregard. (2020). Bacillus subtilis and Bacillus velezensis population dynamics and quantification of spores after inoculation on ornamental plants. Canadian Journal of Microbiology. DOI
• Adrien Rizzi, Julie Leroux, Vincent Charron-Lamoureux, Sébastien Roy, Pascale B. Beauregard, Jean-Philippe Bellenger. (2020). Bacillus subtilis Modulates Its Usage of Biofilm-Bound Iron in Response to Environmental Iron Availability. Applied and Environmental Microbiology. DOI
• Vincent Charron-Lamoureux, Pascale B. Beauregard. (2019). Arabidopsis thaliana Seedlings Influence Bacillus subtilis Spore Formation. Molecular Plant-Microbe Interactions®. DOI
• Kaley McCluskey, Julien Boudreault, Patrick St-Pierre, Cibran Perez-Gonzalez, Adrien Chauvier, Adrien Rizzi, Pascale B Beauregard, Daniel A Lafontaine, J Carlos Penedo. (2019). Unprecedented tunability of riboswitch structure and regulatory function by sub-millimolar variations in physiological Mg2+. Nucleic Acids Research. DOI
• Adrien Rizzi, Sébastien Roy, Jean-Philippe Bellenger, Pascale B. Beauregard. (2019). Iron Homeostasis in Bacillus subtilis Requires Siderophore Production and Biofilm Formation. Applied and Environmental Microbiology. DOI
• Frédéric Lécuyer, Jean-Sébastien Bourassa, Martin Gélinas, Vincent Charron-Lamoureux, Vincent Burrus, Pascale B. Beauregard. (2018). Biofilm Formation Drives Transfer of the Conjugative Element ICE <i>Bs1</i> in <i>Bacillus subtilis</i>. mSphere. DOI
• Maxime Lamontagne Boulet, Charles Isabelle, Isabelle Guay, Eric Brouillette, Jean-Philippe Langlois, Pierre-Étienne Jacques, Sébastien Rodrigue, Ryszard Brzezinski, Pascale B. Beauregard, Kamal Bouarab, Kumaraswamy Boyapelly, Pierre-Luc Boudreault, Éric Marsault, François Malouin. (2018). Tomatidine Is a Lead Antibiotic Molecule That Targets Staphylococcus aureus ATP Synthase Subunit C. Antimicrobial Agents and Chemotherapy. DOI
• Rosalie Allard-Massicotte, Laurence Tessier, Frédéric Lécuyer, Venkatachalam Lakshmanan, Jean-François Lucier, Daniel Garneau, Larissa Caudwell, Hera Vlamakis, Harsh P. Bais, Pascale B. Beauregard. (2016). Bacillus subtilis Early Colonization of Arabidopsis thaliana Roots Involves Multiple Chemotaxis Receptors. mBio. DOI
• Pascale B. Beauregard, Yunrong Chai, Hera Vlamakis, Richard Losick, Roberto Kolter. (2013). Bacillus subtilis biofilm induction by plant polysaccharides. Proceedings of the National Academy of Sciences. DOI
• Hera Vlamakis, Yunrong Chai, Pascale Beauregard, Richard Losick, Roberto Kolter. (2013). Sticking together: building a biofilm the Bacillus subtilis way. Nature Reviews Microbiology. DOI
• Yunrong Chai, Pascale B. Beauregard, Hera Vlamakis, Richard Losick, Roberto Kolter. (2012). Galactose Metabolism Plays a Crucial Role in Biofilm Formation by Bacillus subtilis. mBio. DOI
• Renée Guérin, Pascale B. Beauregard, Alexandre Leroux, Luis A. Rokeach. (2009). Calnexin Regulates Apoptosis Induced by Inositol Starvation in Fission Yeast. PLoS ONE. DOI
• Pascale B. Beauregard, Renée Guérin, Cynthia Turcotte, Susan Lindquist, Luis A. Rokeach. (2009). A nucleolar protein allows viability in the absence of the essential ER-residing molecular chaperone calnexin. Journal of Cell Science. DOI
• Cynthia Turcotte, Antoine Roux, Pascale B. Beauregard, Renée Guérin, Patrick Sénéchal, Fadi Hajjar, Luis A. Rokeach. (2007). The calnexin-independent state does not compensate for all calnexin functions in<i>Schizosaccharomyces pombe</i>. FEMS Yeast Research. DOI
• Fadi Hajjar, Pascale B. Beauregard, Luis A. Rokeach. (2007). The 160 N‐terminal residues of calnexin define a novel region supporting viability in Schizosaccharomyces pombe. Yeast. DOI
• Philippe Collin, Pascale B. Beauregard, Aram Elagöz, Luis A. Rokeach. (2004). A non-chromosomal factor allows viability of<i>Schizosaccharomyces pombe</i>lacking the essential chaperone calnexin. Journal of Cell Science. DOI

Chapitres de livre

• Pascale B. Beauregard. (2015). Not Just Sweet Talkers. Advances in Botanical Research. DOI

Autres contributions

Cours enseignés à l'UdeS

• BIO718 - Rédaction et communication scientifiques. (2026). (1CR).
• MCB404 - Laboratoire de microbiologie clinique et environnementale. (2024-2025). (1CR).
• MCB607 - Communautés et interactions microbiennes dans l’environnement. (2024-2025). (3CR).
• MCB609 - Projet d'identification et de caractérisation bactérienne. (2025). (3CR).
• MCB603 - Microbiologie clinique et environnementale II - Travaux pratiques. (2023-2024). (2CR).
• MCB403 - Microbiologie clinique et environnementale I - Travaux pratiques. (2023). (1CR).
• MCB534 - Environnement et biosphère. (2023). (3CR).

Activités professionnelles

• NSERC. Evaluation panel - Discovery grants. Ottawa, Ontario, Canada. (2025-2028).
• Tri-agency. NFRF evaluation panel. Ottawa, Canada. (2024).
• Biofilm. Editor. (2021-).
• Canadian Society of Microbiologists. Executive committee. Ottawa, Ontario, Canada. (2020-2024).
• Canadian Society of Plants Biologists. Ragai Ibrahim Award Committee. Ottawa, Canada. (2019-2022).
• Fonds de recherche du Québec. Evaluation committee; Msc fellowship. Québec, Quebec, Canada. (2017-2024).