Pascal Tétreault

Financement

• Subvention. La douleur chronique : un angle mort dans l’évaluation du risque cérébrovasculaire. Brain Canada Foundation (Montreal, Canada). Futurs leaders canadiens de la recherche sur le cerveau 2025. 100 000 $. (2026-2028).
• Subvention. Dysplasie corticale focale et épilepsie réfractaire: comprendre les mécanismes. Centre de Recherche du Centre Hospitalier de l'Université de Sherbrooke Inc. (CRCHUS) (Sherbrooke, Canada). 17 000 DEM. (2024-2025).
• Subvention. Immunological and neurological quantitative traits to dissect causal genetic pathways leading to chronic pain. Réseau québécois de recherche sur la douleur (Montreal, Canada). 25 000 $. (2024-2025).
• Subvention. Development and performance of a model combining a polygenic risk score and biopsychosocial measures to predict the transition of acute to chronic low back pain. Canadian Institutes of Health Research (Ottawa, Canada). 596 700 $. (2023-2028).
  Numéro de subvention : 202303PJT. Voir plus
• Subvention. The Quebec Back Pain Consortium: An Integrative Approach to Understanding Pain Trajectories. Canadian Institutes of Health Research (Ottawa, Canada). 25 000 $. (2023-2024).
  Numéro de subvention : 202302RE9. Voir plus
• Subvention. The Quebec Back Pain Consortium: An Integrative Approach to Understanding Pain Trajectories. Canadian Institutes of Health Research (Ottawa, Canada). CIHR-IMHA Inclusive Research Excellence Prize - Team Science Grand New. 25 000 $. (2023-2024).
• Subvention. Prédire la réponse aux traitements pour la douleur chronique lombaire avec l'imagerie par résonance magnétique. Canadian Institutes of Health Research (Ottawa, Canada). 108 333 $. (2022-2025).
  Numéro de subvention : 202111FBD. Voir plus
• Subvention. Cartographie cérébrale par IRMf de la perception de sons synthétiques et naturels. Centre de recherche du CHUS Medical Imaging Axis (Sherbrooke, Canada). Pilot Study. 10 000 $. (2022-2024).
• Subvention. Cartographie acoustique- cérébrale-cognitive de la perception des alarmes sonores. Fonds Institutionnel de Recherche de l'Université de Sherbrooke (Sherbrooke, Canada). 10 000 $. (2022-2023).
• Subvention. Évaluer la prédictibilité de déterminants cérébraux, comportementaux et génétiques pour l'optimisation des traitements pour la douleur chronique lombaire. Fonds de Recherche du Québec - Santé (Montreal, Canada). 40 000 $. (2022-2024).
  Numéro de subvention : 324254. Voir plus
• Subvention. Évaluer la prédictibilité de déterminants cérébraux, comportementaux et génétiques pour l'optimisation des traitements pour la douleur chronique lombaire. Fonds de Recherche du Québec - Santé (Montreal, Canada). 277 526 $. (2022-2026).
  Numéro de subvention : 311042. Voir plus
• Subvention. Startup funds Université de Sherbrooke. Fonds de Dotation de la Faculté de Médecine de l'Université de Sherbrooke (Sherbooke, Canada). Startup funds. 45 000 $. (2022-2026).
  Numéro de subvention : Tetreault_2022.
• Subvention. Evaluating predictability of brain and psychometric determinants for the optimization of chronic low back pain treatment. Arthritis Society (The) (Montreal, Canada). 375 000 $. (2022-2025).
  Numéro de subvention : 21-0000000041.
• Subvention. Linking multimodal MRI metrics and their changes to histological underpinnings. Natural Sciences and Engineering Research Council (Ottawa, Canada). 28 000 $. (2021-2022).
  Numéro de subvention : RGPIN-2021-03669. Voir plus
• Subvention. Linking multimodal MRI metrics and their changes to histological underpinnings. Natural Sciences and Engineering Research Council (Ottawa, Canada). 12 500 $. (2021-2022).
  Numéro de subvention : DGECR-2021-00483. Voir plus
• Subvention. Le projet MAPS : Mesure de résultAt Pronostic muSculosquelettique Personnaliser les soins de réadaptation des travailleurs aux prises avec des troubles musculosquelettiques via les outils pronostiques. REPAR (Montreal, Canada). 39 969 $. (2021-2022).
• Subvention. Quebec Bio-Imaging Network regular competition of pilot projec. Quebec Bio-Imaging Network (Sherbrooke, Canada). 20 000 $. (2020-2022).
• Subvention. Programme d’aide aux jeunes chercheurs de l’Axe d’imagerie médicale du CRCHUS et du Centre d’imagerie médicale de l’Université de Sherbrooke. Axe imagerie médicale du CRCHUS et centre imagerie médicale de l'Université de Sherbrooke (Sherbrooke, Canada). 25 000 $. (2020-2022).
• Subvention. Startup funds from the anesthesiology department, the CRCHUS, the UdeS medical faculty and the institut de Pharmacology de Sherbrooke (IPS). Fonds Institutionnel de Recherche de l'Université de Sherbrooke (Sherbrooke, Canada). 234 000 $. (2020-2026).
• Subvention. Projet pilote du Réseau Québécois de Recherche sur la Douleur (RQRD)/Quebec Pain Research Network (QPRN). Réseau québécois de recherche sur la douleur (Montreal, Canada). 25 000 $. (2020-2022).
• Subvention. High-Resolution Magnetic Imaging for the Study of Brain Development. Canadian Institutes of Health Research (Ottawa, Canada). 147 917 $. (2015-2018).
  Numéro de subvention : 201311MFE. Voir plus
• Subvention. Plasticité fonctionnelle de la voie cortico-striatale dans la transition d'une douleur aiguë vers un syndrome douloureux chronique. Fonds de Recherche du Québec - Santé (Montreal, Canada). 33 750 $. (2014-2015).
  Numéro de subvention : 30071. Voir plus
• Subvention. Etude de l'interaction fonctionelle entre le récepteur NTS2 et la sécrétogranine. Natural Sciences and Engineering Research Council (Ottawa, Canada). 21 000 $. (2009-2010).
  Numéro de subvention : 379197-2009. Voir plus

Publications

Articles

• Chan Nam Nguyen, Julia Huck, Davy C. Vanderweyen, Samantha Côté, Tatjana Rundek, Mitchell S.V. Elkind, Jose Gutierrez, Pascal Tétreault, Kevin Whittingstall. (2026). Automatic Detection of Mild Intracranial Stenosis using Time-of-Flight Magnetic Resonance Angiography. American Journal of Neuroradiology. DOI
• Vincent Doyon, Félix Janelle, Monica Sean, Davy Vanderweyen, Samantha Côté, Julia Huck, Pascal Tétreault, Jean-François Lepage, Jose Gutierrez, Christian Bocti, Tamàs Fülöp, Alexa Pichet-Binette, Kevin Whittingstall. (2026). A vascular component to the selective vulnerability of the medial temporal lobe to tau pathology. Brain Communications. DOI
• Marc-Antoine Fortier, Graham Little, Paul Bautin, Monica Sean, Pascal Tétreault. (2026). Towards repeatable and converging methods in diffusion MRI: Evidence from a longitudinal chronic pain cohort. Aperture Neuro. DOI
• Monica Sean, Samantha Cote, Alexia Coulombe‐Lévêque, Julia Huck, Marylie Martel, Ze Ming Liu, Guillaume Léonard, Kevin Whittingstall, Pascal Tétreault. (2026). Distinct Grey Matter Alterations in Untreated Mild to Moderate Chronic Low Back Pain: A Longitudinal Magnetic Resonance Imaging Study. European Journal of Pain. DOI
• Vincent Doyon, Félix Janelle, Samantha Côté, Monica Sean, Davy Vanderweyen, Julia Huck, Christian Bocti, Pascal Tétreault, Kevin Whittingstall. (2025). A vascular component to the selective vulnerability of the medial temporal lobe in Alzheimer's disease. Alzheimer's & Dementia. DOI
• Rachael O. Osagie, Iulia Tufa, Adriana Angarita-Fonseca, M. Gabrielle Pagé, Anaïs Lacasse, Laura S. Stone, Pierre Rainville, Mathieu Roy, Pascal Tétreault, Maryse Fortin, Guillaume Léonard, Hugo Massé-Alarie, Jean-Sébastien Roy, Audrey V. Grant, Carolina B. Meloto. (2025). Impact of different acute low back pain definitions on the predictors and on the risk of transition to chronic low back pain: a prospective longitudinal cohort study. Pain. DOI
• Nathalie Desmarais, Simon Décary, Catherine Houle, Christian Longtin, Thomas Gerard, Kadija Perreault, Emilie Lagueux, Pascal Tétreault, Marc-André Blanchette, Hélène Beaudry, Yannick Tousignant-Laflamme. (2025). Personalizing rehabilitation for individuals with musculoskeletal impairments: Feasibility of implementation of the Measures Associated to Prognostic (MAPS) tool. Physiotherapy Theory and Practice. DOI
• Paul Bautin, Marc-Antoine Fortier, Monica Sean, Graham Little, Marylie Martel, Maxime Descoteaux, Guillaume Léonard, Pascal Tétreault. (2025). What has brain diffusion magnetic resonance imaging taught us about chronic primary pain: a narrative review. Pain. DOI
• Monica Sean, Alexia Coulombe-Lévêque, William Nadeau, Anne-Catherine Charest, Marylie Martel, Guillaume Léonard, Pascal Tétreault. (2024). Counting your chickens before they hatch: improvements in an untreated chronic pain population, beyond regression to the mean and the placebo effect. PAIN Reports. DOI
• Meagan Anstruther, Monica Sean, Pascal Tétreault, Maryse Fortin. (2024). Paraspinal Muscle Changes in Individuals with and without Chronic Low Back Pain over a 4-Month Period: A Longitudinal MRI Study. Medicina. DOI
• Yannick Tousignant‐Laflamme, Catherine Houle, Christian Longtin, Nathalie Desmarais, Thomas Gérard, Kadija Perreault, Emilie Lagueux, Pascal Tétreault, Marc‐André Blanchette, Hélène Beaudry, Simon Décary. (2024). Establishing the prognostic profile of patients with work‐related musculoskeletal disorders: Development and acceptability of the MAPS questionnaire. Physiotherapy Research International. DOI
• Brent Rosenstein, Jessica Burdick, Alexa Roussac, Meaghan Rye, Neda Naghdi, Stephanie Valentin, Theresia Licka, Monica Sean, Pascal Tétreault, Jim Elliott, Maryse Fortin. (2024). The assessment of paraspinal muscle epimuscular fat in participants with and without low back pain: A case-control study. Journal of Biomechanics. DOI
• Yannick Tousignant-Laflamme, Catherine Houle, Christian Longtin, Thomas Gérard, Emilie Lagueux, Kadija Perreault, Hélène Beaudry, Pascal Tétreault, Marc-André Blanchette, Simon Décary. (2023). Prognostic factors specific to work-related musculoskeletal disorders: An overview of recent systematic reviews. Musculoskeletal Science and Practice. DOI
• Adriana Angarita-Fonseca, M. Gabrielle Pagé, Carolina B. Meloto, Erika Lauren Gentile, Guillaume Léonard, Hugo Massé-Alarie, Iulia Tufa, Jean-Sébastien Roy, Laura S. Stone, Manon Choinière, Maryse Fortin, Mathieu Roy, Monica Sean, Pascal Tétreault, Pierre Rainville, Simon Deslauriers, Anaïs Lacasse. (2023). The Canadian version of the National Institutes of Health minimum dataset for chronic low back pain research: reference values from the Quebec Low Back Pain Study. Pain. DOI
• Hugo Massé-Alarie, Adriana Angarita-Fonseca, Anaïs Lacasse, M. Gabrielle Pagé, Pascal Tétreault, Maryse Fortin, Guillaume Léonard, Laura S. Stone, Jean-Sébastien Roy. (2022). Low back pain definitions: effect on patient inclusion and clinical profiles. PAIN Reports. DOI
• Diane Reckziegel, Pascal Tétreault, Mariam Ghantous, Kenta Wakaizumi, Bogdan Petre, Lejian Huang, Rami Jabakhanji, Taha Abdullah, Etienne Vachon-Presseau, Sara Berger, Alexis Baria, James W. Griffith, Marwan N. Baliki, Thomas J. Schnitzer, A. Vania Apkarian. (2021). Sex-Specific Pharmacotherapy for Back Pain: A Proof-of-Concept Randomized Trial. Pain and Therapy. DOI
• Ariana J. Cahn, Graham Little, Christian Beaulieu, Pascal Tétreault. (2021). Diffusion properties of the fornix assessed by deterministic tractography shows age, sex, volume, cognitive, hemispheric, and twin relationships in young adults from the Human Connectome Project. Brain Structure and Function. DOI
• Pascal Tétreault, Élie Besserer-Offroy, Rebecca L. Brouillette, Adeline René, Alexandre Murza, Roberto Fanelli, Karyn Kirby, Alexandre J. Parent, Isabelle Dubuc, Nicolas Beaudet, Jérôme Côté, Jean-Michel Longpré, Jean Martinez, Florine Cavelier, Philippe Sarret. (2020). Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog. European Journal of Pharmacology. DOI
• Élie Besserer-Offroy, Pascal Tétreault, Rebecca L Brouillette, Adeline René, Alexandre Murza, Roberto Fanelli, Karyn Kirby, Alexandre Parent, Isabelle Dubuc, Nicolas Beaudet, Jérôme Côté, Jean-Michel Longpré, Jean Martinez, Florine Cavelier, Philippe Sarret. (2020). Data set describing the in vitro biological activity of JMV2009, a novel silylated neurotensin(8–13) analog. Data in Brief. DOI
• Pascal Tétreault, Kevin D. Harkins, Corey A. Baron, Rob Stobbe, Mark D. Does, Christian Beaulieu. (2020). Diffusion time dependency along the human corpus callosum and exploration of age and sex differences as assessed by oscillating gradient spin-echo diffusion tensor imaging. NeuroImage. DOI
• Pascal Tétreault. (2019). Can Functional Brain Connectivity Predict Placebo Response in Chronic Pain?. Clinical Pharmacology & Therapeutics. DOI
• Simon Duchesne, Louis Dieumegarde, Isabelle Chouinard, Farnaz Farokhian, Amanpreet Badhwar, Pierre Bellec, Pascal Tétreault, Maxime Descoteaux, Arnaud Boré, Jean-Christophe Houde, Christian Beaulieu, Olivier Potvin. (2019). Structural and functional multi-platform MRI series of a single human volunteer over more than fifteen years. Scientific Data. DOI
• Pascal Tétreault, Marwan N. Baliki, Alexis T. Baria, William R. Bauer, Thomas J. Schnitzer, A. Vania Apkarian. (2018). Inferring distinct mechanisms in the absence of subjective differences: Placebo and centrally acting analgesic underlie unique brain adaptations. Human Brain Mapping. DOI
• Parent, A.J., Tétreault, P., Roux, M., Belleville, K., Longpré, J.-M., Beaudet, N., Goffaux, P., Sarret, P. (2016). Descending nociceptive inhibition is modulated in a time-dependent manner in a double-hit model of chronic/tonic pain. Neuroscience. DOI
• Tetreault, P., Baliki, M., Vachon-Presseau, E., Yeasted, R., Schnitzer, T. J., Apkarian, A. (2015). CORTICAL SINGULARITY OF KNEE OSTEOARTHRITIS PATIENTS AND THEIR RESPONSE TO DULOXETINE OR PLACEBO TREATMENT. Osteoarthritis and Cartilage.
• Fanelli, R., Besserer-Offroy, E., René, A., Côté, J., Tétreault, P., Collerette-Tremblay, J., Longpré, J.-M., Leduc, R., Martinez, J., Sarret, P., Cavelier, F. (2015). Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues. Journal of Medicinal Chemistry. DOI
• Demeule, M., Beaudet, N., Régina, A., Besserer-Offroy, E., Murza, A., Tétreault, P., Belleville, K., Ché, C., Larocque, A., Thiot, C., Béliveau, R., Longpré, J.-M., Marsault, E., Leduc, R., Lachowicz, J.E., Gonias, S.L., Castaigne, J.-P., Sarret, P. (2014). Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties. Journal of Clinical Investigation. DOI
• Tetreault, Pascal, Baliki, Marwan, Vachon-Presseau, Etienne, Yeasted, Renita Evonne, Schnitzer, Thomas J., Apkarian, A. Vania. (2014). Cortical Reorganization after Duloxetine Treatment-Related Pain Decrease in Knee Osteoarthritis. Arthritis & Rheumatology.
• Cavelier, F., Rene, A., Tetreault, P., Lafrance, M., Fanellia, R., Floque, N., Sarret, P., Martinez, J. (2014). DESIGN, SYNTHESIS AND IN VIVO STUDIES OF NEW STABLE NEUROTENSIN ANALOGUES AS POTENT ANTINOCICEPTIVE AGENTS. Journal of Peptide Science.
• Belkouch, M., Dansereau, M.-A., Tétreault, P., Biet, M., Beaudet, N., Dumaine, R., Chraibi, A., Mélik-Parsadaniantz, S., Sarret, P. (2014). Functional up-regulation of Nav1.8 sodium channel in Aβ afferent fibers subjected to chronic peripheral inflammation. Journal of Neuroinflammation. DOI
• Parent, A., Tetreault, P., Roux, M., Belleville, K., Auray-Blais, C., Goffaux, P., Sarret, P. (2013). Chronic neuropathic pain provokes adaptive changes in the response of endogenous pain inhibition in rats. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Besserer-Offroy, E., Tetreault, P. G., Lafrance, M., Murza, A., Rene, A., Longpre, J. -M., Cavelier, F., Martinez, J., Marsault, E., Leduc, R., Sarret, P. (2013). Deciphering the NTS1 receptor signalling pathways leading to analgesia and hypothermia. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Midavaine, E., Barriere, D., Tetreault, P., Longpre, J. -M., Sarret, P. (2013). Pharmacological inhibition of the CCL2/CCR2 chemokinergic system reduces bone cancer-related pain behaviors. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Tétreault, P., Beaudet, N., Perron, A., Belleville, K., René, A., Cavelier, F., Martinez, J., Stroh, T., Jacobi, A.M., Rose, S.D., Behlke, M.A., Sarret, P. (2013). Spinal NTS2 receptor activation reverses signs of neuropathic pain. FASEB Journal. DOI
• Besserer-Offroy, E., Demeule, M., Beaudet, N., Regina, A., Tetreault, P., Belleville, K., Che, C., Larocque, A., Lachowicz, J. E., Castaigne, J. P., Sarret, P. (2013). Use of Peptide Technology for Analgesic Brain Delivery. Biopolymers.
• Rene, A., Tetreault, P., Beaudet, N., Sarret, P., Martinez, J., Cavelier, F. (2012). JMV 2009, a Neurotensin Analogue as Potent Antinociceptive Agent. Journal of Peptide Science.
• Sarret, P., Tetreault, P. G., Parent, A., Besserer-Offroy, E., Murza, A., Rene, A., Dubuc, I., Beaudet, N., Leduc, R., Marsault, E., Martinez, J., Cavelier, F. (2012). Neurotensin receptor-based therapy: Achieving analgesia without opioid-related side effects. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Parent, A., Beaudet, N., Shooner, J., Tetreault, P., Gagnon, R., Fortin, M., Daigle, K., Sabbagh, R., Sansoucy, Y., Auray-Blais, C., Sarret, P., Goffaux, P. (2012). Relationship between endogenous pain inhibition in patients with chronic pain and neuropeptide concentrations in cerebrospinal fluid and plasma. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Tetreault, P. G., Beaudet, N., Martinez, J., Cavelier, F., Sarret, P. (2012). Spinal NTS2 agonists reverses signs of neuropathic pain. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Tetreault, P. G., Dansereau, M. -A., Dore-Savard, L., Beaudet, N., Sarret, P. (2011). Dynamic weight bearing: From characterization to drug screening. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Tétreault, P., Dansereau, M.-A., Doré-Savard, L., Beaudet, N., Sarret, P. (2011). Weight bearing evaluation in inflammatory, neuropathic and cancer chronic pain in freely moving rats. Physiology and Behavior. DOI
• Sarret, Philippe, Dore-Savard, Louis, Tetreault, Pascal, Begin-Lavallee, Valerie, Beaudet, Nicolas, Erdmann, VA, Barciszewski, J. (2010). Application of Dicer-Substrate siRNA in Pain Research. Rna Technologies and Their Applications. DOI
• Tetreault, P. G., Belleville, K., Martinez, J., Beaudet, N., Sarret, P. (2010). Reduced nerve injury induced neuropathic pain in NTS2 agonist treated rats. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Tetreault, P. G., Dore-Savard, L., Roussy, G., Dansereau, M. -A., Belleville, K., Rose, S. D., Jacobi, A. M., Beaudet, N., Behlke, M. A., Sarret, P. (2009). Functional inhibition of NTS2 receptors by Dicer-substrate siRNA modulates tonic pain perception. Society for Neuroscience Abstract Viewer and Itinerary Planner.
• Tetreault, P. G., Guillemette, A., Belleville, K., Martinez, J., Beaudet, N., Sarret, P. (2009). NTS2 receptor activation as an innovative target for the treatment of neuropathic pain. Society for Neuroscience Abstract Viewer and Itinerary Planner.

Livres

• Vania Apkarian, A., Baliki, M.N., Farmer, M.A., Tétreault, P., Vachon-Presseau, E. (2015). Pain: Acute and Chronic. Brain Mapping: An Encyclopedic Reference. DOI
• Sarret, P., Doré-Savard, L., Tétreault, P., Bégin-Lavallée, V., Dansereau, M.-A., Beaudet, N. (2011). Using RNA interference to downregulate G protein-coupled receptors. Neuromethods. DOI

Autres contributions

Cours enseignés ou supervisés à l'UdeS

• RBL501 - Études pharmacologiques en imagerie biomédicale et radiothérapie. (2023-2024, 2026). (2CR).