Luis Daniel Cruz Zaragoza

Publications

Articles

• Bettina Warscheid, Stefan Jakobs, Sven Dennerlein, Peter Rehling, Michael Lidschreiber, Silke Oeljeklaus, Julian Bender, Luis Daniel Cruz-Zaragoza, Mats Koschel, Mehmet Yilmaz, Marcel Morgenstern, Angela Boshnakovska, Jan-Niklas Dohrke, Kristine A Henningfeld, Aiturgan Zheenbekova, Drishan Dahal, Laura S Kremer, Mirjam Breuer, Oliver Urbach, Anusha Ramesh Valpadashi. (2025). Silencing mitochondrial gene expression in living cells. Science. DOI
• Roya Yousefi, Luis Daniel Cruz-Zaragoza, Anusha Valpadashi, Carina Hansohn, Drishan Dahal, Ricarda Richter-Dennerlein, Silvio Rizzoli, Henning Urlaub, Peter Rehling, David Pacheu-Grau. (2025). A microscopy-based screen identifies cellular kinases modulating mitochondrial translation. Cell Reports. DOI
• Carmichael RE, Oeljeklaus S, Cruz-Zaragoza LD, Kumar R, Bolton C, Islinger M, Kunze M, Pata J, Lismont C, Silva BSC, Kors S, Schrader M, Erdmann R. (2025). Seventy years of peroxisome research: current advances and future perspectives. Histochemistry and cell biology. DOI
• Koschel M, Cruz-Zaragoza LD. (2024). In organello silencing of mitochondrial gene expression. Methods in enzymology. DOI
• Sabine Poerschke, Silke Oeljeklaus, Luis Daniel Cruz-Zaragoza, Alexander Schenzielorz, Drishan Dahal, Hauke Sven Hillen, Hirak Das, Laura Sophie Kremer, Anusha Valpadashi, Mirjam Breuer, Johannes Sattmann, Ricarda Richter-Dennerlein, Bettina Warscheid, Sven Dennerlein, Peter Rehling. (2024). Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria. Molecular Cell. DOI
• Hazel Stewart, Yongxu Lu, Sarah O’Keefe, Anusha Valpadashi, Luis Daniel Cruz-Zaragoza, Hendrik A. Michel, Samantha K. Nguyen, George W. Carnell, Nina Lukhovitskaya, Rachel Milligan, Yasmin Adewusi, Irwin Jungreis, Valeria Lulla, David A. Matthews, Stephen High, Peter Rehling, Edward Emmott, Jonathan L. Heeney, Andrew D. Davidson, ... Andrew E. Firth. (2023). The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity. iScience. DOI
• Naintara Jain, Ridhima Gomkale, Olaf Bernhard, Peter Rehling, Luis Daniel Cruz‐Zaragoza. (2023). A quantitative fluorescence‐based approach to study mitochondrial protein import. EMBO reports. DOI
• Eden Yifrach, Markus Rudowitz, Luis Daniel Cruz-Zaragoza, Asa Tirosh, Zohar Gazi, Yoav Peleg, Markus Kunze, Miriam Eisenstein, Wolfgang Schliebs, Maya Schuldiner, Ralf Erdmann, Einat Zalckvar. (2023). Determining the targeting specificity of the selective peroxisomal targeting factor Pex9. Biological Chemistry. DOI
• Homberg B, Rehling P, Cruz-Zaragoza LD. (2023). The multifaceted mitochondrial OXA insertase. Trends in cell biology. DOI
• Rudowitz M, Cruz-Zaragoza LD, Girzalsky W, Erdmann R. (2023). Utilization of Nonstop mRNA to Assess Ribosome-Associated Nascent Polypeptide Chains in Early Topogenesis of Peroxisomal Proteins. Methods in molecular biology (Clifton, N.J.). DOI
• Franziska Nadler, Elena Lavdovskaia, Angelique Krempler, Luis Daniel Cruz-Zaragoza, Sven Dennerlein, Ricarda Richter-Dennerlein. (2022). Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control. Nature Communications. DOI
• (2021). An in vitro system to silence mitochondrial gene expression. Cell. DOI
• Ridhima Gomkale, Andreas Linden, Piotr Neumann, Alexander Benjamin Schendzielorz, Stefan Stoldt, Olexandr Dybkov, Markus Kilisch, Christian Schulz, Luis Daniel Cruz-Zaragoza, Blanche Schwappach, Ralf Ficner, Stefan Jakobs, Henning Urlaub, Peter Rehling. (2021). Mapping protein interactions in the active TOM-TIM23 supercomplex. Nature Communications. DOI
• (2020). A piggybacking mechanism enables peroxisomal localization of the glyoxylate cycle enzyme Mdh2 in yeast. Journal of Cell Science. DOI
• (2020). From TOM to the TIM23 complex – handing over of a precursor. Biological Chemistry. DOI
• (2020). Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos. Current Biology. DOI
• Wróblewska, J.P., Cruz-Zaragoza, L.D., Yuan, W., Schummer, A., Chuartzman, S.G., de Boer, R., Oeljeklaus, S., Schuldiner, M., Zalckvar, E., Warscheid, B., Erdmann, R., van der Klei, I.J. (2017). Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins. Biochimica et Biophysica Acta - Molecular Cell Research. DOI
• Chan, A., Schummer, A., Fischer, S., Schröter, T., Cruz-Zaragoza, L.D., Bender, J., Drepper, F., Oeljeklaus, S., Kunau, W.-H., Girzalsky, W., Warscheid, B., Erdmann, R. (2016). Pex17p-dependent assembly of Pex14p/Dyn2p-subcomplexes of the peroxisomal protein import machinery. European Journal of Cell Biology. DOI
• Effelsberg, D., Cruz-Zaragoza, L.D., Schliebs, W., Erdmann, R. (2016). Pex9p is a new yeast peroxisomal import receptor for PTS1-containing proteins. Journal of Cell Science. DOI
• Galiani, S., Waithe, D., Reglinski, K., Cruz-Zaragoza, L.D., Garcia, E., Clausen, M.P., Schliebs, W., Erdmann, R., Eggeling, C. (2016). Super-resolution microscopy reveals compartmentalization of peroxisomal membrane proteins. Journal of Biological Chemistry. DOI
• Perera, Y., Pedroso, S., Borras-Hidalgo, O., Vázquez, D.M., Miranda, J., Villareal, A., Falcón, V., Cruz, L.D., Farinas, H.G., Perea, S.E. (2015). Pharmacologic inhibition of the CK2-mediated phosphorylation of B23/NPM in cancer cells selectively modulates genes related to protein synthesis, energetic metabolism, and ribosomal biogenesis. Molecular and Cellular Biochemistry. DOI
• Effelsberg, D., Cruz-Zaragoza, L.D., Tonillo, J., Schliebs, W., Erdmann, R. (2015). Role of pex 21p for piggyback import of Gpd1p and Pnc1p into peroxisomes of saccharomyces cerevisiae. Journal of Biological Chemistry. DOI
• Díaz-Miranda, M., Vázquez-Blomquist, D., Cruz, L.D., Vasallo, C., Campos, T., Pérez, J.E., Paneque, D., Duarte, C.A. (2012). Sequence of the gene coding for the p26 protein from a Cuban strain of Equine Infectious Anemia Virus. Biotecnologia Aplicada.

Livres

• Luis Daniel Cruz Zaragoza, Ralf Erdmann, Thomas Günther-Pomorski. (2018). New insights into de novo synthesis of peroxisomes and into alternative peroxisomal protein import pathways in Saccharomyces cerevisiae. Allemagne.

Autres contributions

Cours enseignés ou supervisés à l'UdeS

• BIM607 - Biologie moléculaire de la cellule. (2026). (3CR).