Louis Gendron
Vice-doyen, Faculté de médecine et des sciences de la santé
Présentation
Expériences académiques
- Professor. (2006-). Université de Sherbrooke. Sherbrooke, Quebec, Canada.
Financement
-
Subvention.
G protein-coupled receptor interactome: Discovery and study of novel neighboring and interacting partners.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
34 000 $.
(2015-2016).
Numéro de subvention : 590286. Voir plus -
Subvention.
Design, preparation and biological evaluation of libraries of marocyclic delta opioid receptor agonists for the treatment of pain.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
43 400 $.
(2015-2016).
Numéro de subvention : 577203. Voir plus -
Subvention.
Design, synthesis and characterization of novel enkephalin analogs for the delta opioid receptor.
Canadian Institutes of Health Research
(Ottawa, Canada).
398 705 $.
(2014-2019).
Numéro de subvention : aab56dc32a7f664f78b943c47b711ecc. Voir plus -
Subvention.
Annual Congress-Inflammation Pain.
Canadian Institutes of Health Research
(Ottawa, Canada).
22 368 $.
(2013-2014).
Numéro de subvention : 2b145f3cde6d338b63457fa0f313c838. Voir plus -
Subvention.
Cellular and physiological consequences of opioid receptor interactions.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
36 000 $.
(2013-2014).
Numéro de subvention : 527288. Voir plus -
Subvention.
Roles, regulation, receptor mechanisms of action of opioid delta in pain.
Canadian Institutes of Health Research
(Ottawa, Canada).
724 385 $.
(2012-2017).
Numéro de subvention : 62aa04de4efc31804c1ba0a173ab5898. Voir plus -
Subvention.
Molecular mechanisms and cellular desensitization of the opioid delta receptor.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
26 750 $.
(2012-2013).
Numéro de subvention : 504094. Voir plus -
Subvention.
An institutional LC-MS platform for research in pharmacology and medicinal chemistry.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
147 201 $.
(2012-2013).
Numéro de subvention : 507084. Voir plus -
Subvention.
Roles, regulatory and receptor delta opioid mechanisms of action in the treatment of pain.
Fonds de Recherche du Québec
(Montreal, Canada).
267 401 $.
(2011-2015).
Numéro de subvention : 22460. Voir plus -
Subvention.
Peptide synthesizer for research in pharmacology and medicinal chemistry. Peptide Synthesizer for research in pharmacology and medicinal chemistry.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
100 551 $.
(2011-2012).
Numéro de subvention : 495940. Voir plus -
Subvention.
Development of new therapeutic strategies to stop metastasis and subsequent chronic pain in cancer.
Canadian Institutes of Health Research
(Ottawa, Canada).
445 569 $.
(2010-2013).
Numéro de subvention : f131066ff72ca593d15c1300ea3c1d6d. Voir plus -
Subvention.
1st Symposium Pain and Francophonie: Challenges Translational. (Satellite Official 13th Congress Mo.
Canadian Institutes of Health Research
(Ottawa, Canada).
9 015 $.
(2010-2011).
Numéro de subvention : 490a99c9ad8ab715e91348e211da0a8c. Voir plus -
Subvention.
Identification of neurons subjected to tolerance delta opioid receptor agonists.
Canadian Institutes of Health Research
(Ottawa, Canada).
17 500 $.
(2010-2011).
Numéro de subvention : a7f4e1c38b51b24af3d923f4e83840b6. Voir plus -
Subvention.
Label-free Monitoring of Cellular Signals by Surface Plasmon Resonance.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
236 590 $.
(2010-2013).
Numéro de subvention : 503869. Voir plus -
Subvention.
Design, synthesis and characterization of opioid receptor agonist peptidomimetic of delta.
Canadian Institutes of Health Research
(Ottawa, Canada).
348 856 $.
(2010-2013).
Numéro de subvention : 7ae91ebf15206469b48fe60e7e969f4d. Voir plus -
Subvention.
Role of substance P in the membrane targeting of the opioid delta receptor.
Canadian Institutes of Health Research
(Ottawa, Canada).
17 500 $.
(2009-2010).
Numéro de subvention : e47665c318863b93a2eb5ab04585a8fb. Voir plus -
Subvention.
Role of neuropeptides in the treatment of Anxiety and depression caused by the inflammatory original chronic pain.
Canadian Institutes of Health Research
(Ottawa, Canada).
17 500 $.
(2009-2010).
Numéro de subvention : b4a5b9154d66ecbc31b1e9fbb816f551. Voir plus -
Subvention.
Acquisition of an imaging and analysis system for electron microscopy.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
121 276 $.
(2008-2009).
Numéro de subvention : 412249. Voir plus -
Subvention.
delta opioid receptor roles in the treatment of chronic pain, anxiety and depression.
Canada Foundation for Innovation
(Ottawa, Canada).
136 339 $.
(2007).
Numéro de subvention : CFI7661. Voir plus -
Subvention.
Roles, regulation, receptor mechanisms of action of opioid delta in pain.
Canadian Institutes of Health Research
(Ottawa, Canada).
324 016 $.
(2007-2010).
Numéro de subvention : c296f5697f24920d5a93fc865385a7d0. Voir plus -
Subvention.
Molecular mechanisms and cellular desensitization of the opioid delta receptor.
Natural Sciences and Engineering Research Council of Canada
(Ottawa, Canada).
107 000 $.
(2007-2011).
Numéro de subvention : 458360. Voir plus -
Subvention.
Roles, regulation, receptor delta opioid mechanisms of action in controlling pain.
Fonds de Recherche du Québec
(Montreal, Canada).
15 000 $.
(2007-2010).
Numéro de subvention : 5768. Voir plus -
Subvention.
Roles, regulation, receptor delta opioid mechanisms of action in controlling pain.
Fonds de Recherche du Québec
(Montreal, Canada).
117 849 $.
(2007-2011).
Numéro de subvention : 12049. Voir plus -
Subvention.
Ladressage regulating membrane receptor delta opioid in the central nervous system: Implications for control of nociception.
Canadian Institutes of Health Research
(Ottawa, Canada).
131 500 $.
(2003-2006).
Numéro de subvention : cc3a3a420bf564a71b78008566086e9e. Voir plus
Publications
Articles
- Lounes Haroune, Sabrina Saibi, Jean-Philippe Bellenger, Matthieu Vincenot, Guillaume Léonard, Louis Gendron, Philippe Sarret. (2025). Spotlight on Endocannabinoids in Healthy Individuals Using Volumetric Absorptive Microsampling Combined with LC-MS/MS Analysis. ACS Omega. DOI
- Manon Dussol, Gisela da Silva Borges, Claudie Beaulieu, Hadir Ghorbel, Amélie Descheemaeker, Karine Herault, Daniel Voisin, Philippe Luccarini, Louis Gendron, Radhouane Dallel. (2025). Contribution of peripheral and central delta opioid receptors in the relief of migraine‐like headache in female and male rats. British Journal of Pharmacology. DOI
- M. Vincenot, G. Léonard, C. Cloutier‐Langevin, M. Bordeleau, L. Gendron, F. Camirand Lemyre, S. Marchand. (2025). Exploring the Spectrum of Temporal Summation and Conditioned Pain Modulation Responses in Pain‐Free Individuals Using a Tonic Heat Pain and Cold Pressor Test Paradigms. European Journal of Pain. DOI
- Matthieu Vincenot, Louis-David Beaulieu, Louis Gendron, Serge Marchand, Guillaume Léonard. (2024). Reliability and minimal detectable change of dynamic temporal summation and conditioned pain modulation using a single experimental paradigm. PLOS ONE. DOI
- Charly G. Lecomte, Stephen Mari, Johannie Audet, Sirine Yassine, Angèle N. Merlet, Caroline Morency, Jonathan Harnie, Claudie Beaulieu, Louis Gendron, Alain Frigon. (2023). Neuromechanical Strategies for Obstacle Negotiation during Overground Locomotion following Incomplete Spinal Cord Injury in Adult Cats. The Journal of Neuroscience. DOI
- Johannie Audet, Sirine Yassine, Charly G. Lecomte, Stephen Mari, Félix Soucy, Caroline Morency, Angèle N. Merlet, Jonathan Harnie, Claudie Beaulieu, Louis Gendron, Ilya A. Rybak, Boris I. Prilutsky, Alain Frigon. (2023). Spinal Sensorimotor Circuits Play a Prominent Role in Hindlimb Locomotor Recovery after Staggered Thoracic Lateral Hemisections but Cannot Restore Posture and Interlimb Coordination during Quadrupedal Locomotion in Adult Cats. eneuro. DOI
- Niousha Nazari, Sylvain Bernard, Daniel Fortin, Thomas Marmin, Louis Gendron, Yves L. Dory. (2023). Triple Thorpe–Ingold Effect in the Synthesis of 18‐Membered C3 Symmetric Lactams Stacking as Endless Supramolecular Tubes. Chemistry – A European Journal. DOI
- Charly G. Lecomte, Stephen Mari, Johannie Audet, Angèle N. Merlet, Jonathan Harnie, Claudie Beaulieu, Khaled Abdallah, Louis Gendron, Ilya A. Rybak, Boris I. Prilutsky, Alain Frigon. (2022). Modulation of the gait pattern during split-belt locomotion after lateral spinal cord hemisection in adult cats. Journal of Neurophysiology. DOI
- Béatrice Quirion, Claudie Beaulieu, Laurie Côté, Jean‐Luc Parent, Louis Gendron. (2022). Distribution of delta and mu opioid receptor mRNA in rodent dorsal root ganglia neurons. European Journal of Neuroscience. DOI
- Jade Degrandmaison, Olivier Grisé, Jean‐Luc Parent, Louis Gendron. (2022). Differential barcoding of opioid receptors trafficking. Journal of Neuroscience Research. DOI
- Charlotte Avet, Claudio Sturino, Sébastien Grastilleur, Christian Le Gouill, Meriem Semache, Florence Gross, Louis Gendron, Youssef Bennani, Joseph A. Mancini, Camil E. Sayegh, Michel Bouvier. (2020). The PAR2 inhibitor I-287 selectively targets Gαq and Gα12/13 signaling and has anti-inflammatory effects. Communications Biology. DOI
- Émilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret, Louis Gendron. (2020). Use of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the Brain. The Journal of Pharmacology and Experimental Therapeutics. DOI
- Sophie Berthiaume, Khaled Abdallah, Véronique Blais, Louis Gendron. (2020). Alleviating pain with delta opioid receptor agonists: evidence from experimental models. Journal of Neural Transmission. DOI
- Emilie Eiselt, Simon Gonzalez, Charlotte Martin, Magali Chartier, Cecilia Betti, Jean-Michel Longpré, Florine Cavelier, Dirk Tourwé, Louis Gendron, Steven Ballet, Philippe Sarret. (2019). Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia. ACS Chemical Neuroscience. DOI
- Jean-Louis Beaudeau, Véronique Blais, Brian J. Holleran, Alexandre Bergeron, Graciela Piñeyro, Brigitte Guérin, Louis Gendron, Yves L. Dory. (2019). N-Guanidyl and C-Tetrazole Leu-Enkephalin Derivatives: Efficient Mu and Delta Opioid Receptor Agonists with Improved Pharmacological Properties. ACS Chemical Neuroscience. DOI
- Desbiens, L., Lapointe, C., Gendron, L., Gharagozloo, M., Vincent, L., Pejler, G., Gris, D., D'Orléans-Juste, P. (2019). Experimental autoimmune encephalomyelitis potentiates mouse mast cell protease 4-dependent pressor responses to centrally or systemically administered big endothelin-1. Journal of Pharmacology and Experimental Therapeutics. DOI
- Gharagozloo, M., Mahmoud, S., Simard, C., Yamamoto, K., Bobbala, D., Ilangumaran, S., Smith, M.D., Lamontagne, A., Jarjoura, S., Denault, J.-B., Blais, V., Gendron, L., Vilariño-Güell, C., Dessa Sadovnick, A., Ting, J.P., Calabresi, P.A., Amrani, A., Gris, D. (2019). NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity. PLoS Biology. DOI
- Eiselt, E., Côté, J., Longpré, J.-M., Blais, V., Sarret, P., Gendron, L. (2019). The combination of opioid and neurotensin receptor agonists improves their analgesic/adverse effect ratio. European Journal of Pharmacology. DOI
- Khaled Abdallah, Francis Nadeau, Francis Bergeron, Sylvie Blouin, Véronique Blais, Kelly M. Bradbury, Christine L. Lavoie, Jean-Luc Parent, Louis Gendron. (2018). Adeno-associated virus 2/9 delivery of Cre recombinase in mouse primary afferents. Scientific Reports. DOI
- Willemse, T., Eiselt, E., Hollanders, K., Schepens, W., van Vlijmen, H.W.T., Chung, N.N., Blais, V., Holleran, B., Longpré, J.-M., Schiller, P.W., Maes, B.U.W., Sarret, P., Gendron, L., Ballet, S. (2018). Chemical space screening around Phe<sup>3</sup> in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings. Bioorganic and Medicinal Chemistry Letters. DOI
- Willemse, T., Eiselt, E., Hollanders, K., Schepens, W., van Vlijmen, H.W.T., Chung, N.N., Blais, V., Holleran, B., Longpré, J.-M., Schiller, P.W., Maes, B.U.W., Sarret, P., Gendron, L., Ballet, S. (2018). Corrigendum to “Chemical space screening around Phe <sup>3</sup> in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings” [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320–2323](S0960894X18304049)(10.1016/j.bmcl.2018.05.015). Bioorganic and Medicinal Chemistry Letters. DOI
- Henry, M.S., Bisht, K., Vernoux, N., Gendron, L., Torres-Berrio, A., Drolet, G., Tremblay, M.-È. (2018). Delta opioid receptor signaling promotes resilience to stress under the repeated social defeat paradigm in mice. Frontiers in Molecular Neuroscience. DOI
- Charfi, I., Abdallah, K., Gendron, L., Pineyro, G. (2018). Delta opioid receptors recycle to the membrane after sorting to the degradation path. Cellular and Molecular Life Sciences. DOI
- Ndong, D.B., Blais, V., Holleran, B.J., Proteau-Gagné, A., Cantin-Savoie, I., Robert, W., Nadon, J.-F., Beauchemin, S., Leduc, R., Piñeyro, G., Guérin, B., Gendron, L., Dory, Y.L. (2018). Exploration of the fifth position of leu-enkephalin and its role in binding and activating delta (DOP) and mu (MOP) opioid receptors. Peptide Science. DOI
- Olivier Van der Poorten, Robin Van Den Hauwe, Emilie Eiselt, Cecilia Betti, Karel Guillemyn, Nga N. Chung, François Hallé, Frédéric Bihel, Peter W. Schiller, Dirk Tourwé, Philippe Sarret, Louis Gendron, Steven Ballet. (2017). χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds. ACS Medicinal Chemistry Letters. DOI
- Azadeh Pirisedigh, Véronique Blais, Samia Ait-Mohand, Khaled Abdallah, Brian J. Holleran, Richard Leduc, Yves L. Dory, Louis Gendron, Brigitte Guérin. (2017). Synthesis and Evaluation of a 64Cu-Conjugate, a Selective δ-Opioid Receptor Positron Emission Tomography Imaging Agent. Organic Letters. DOI
- Étienne St-Louis, Jade Degrandmaison, Sébastien Grastilleur, Samuel Génier, Véronique Blais, Christine Lavoie, Jean-Luc Parent, Louis Gendron. (2017). Involvement of the coatomer protein complex I in the intracellular traffic of the delta opioid receptor. Molecular and Cellular Neuroscience. DOI
- Henry, M.S., Gendron, L., Tremblay, M.-E., Drolet, G. (2017). Enkephalins: Endogenous Analgesics with an Emerging Role in Stress Resilience. Neural Plasticity. DOI
- Nadon, J.-F., Rochon, K., Grastilleur, S., Langlois, G., Dao, T.T.H., Blais, V., Guérin, B., Gendron, L., Dory, Y.L. (2017). Synthesis of Gly-ψ[(Z)CFCH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic. ACS Chemical Neuroscience. DOI
- Jean-Sébastien Maltais, Elie Simard, Ulrike Froehlich, Jean-Bernard Denault, Louis Gendron, Michel Grandbois. (2016). iRAGE as a novel carboxymethylated peptide that prevents advanced glycation end product-induced apoptosis and endoplasmic reticulum stress in vascular smooth muscle cells. Pharmacological Research. DOI
- Shi, M., Paquette, B., Thippayamontri, T., Gendron, L., Guérin, B., Sanche, L. (2016). Increased radiosensitivity of colorectal tumors with intra-tumoral injection of low dose of gold nanoparticles. International Journal of Nanomedicine. DOI
- Gendron, L., Cahill, C.M., Von Zastrow, M., Schiller, P.W., Pineyro, G. (2016). Molecular pharmacology of δ-opioid receptors. Pharmacological Reviews. DOI
- Beaudry, H., Gendron, L., Morón, J.A. (2015). Implication of delta opioid receptor subtype 2 but not delta opioid receptor subtype 1 in the development of morphine analgesic tolerance in a rat model of chronic inflammatory pain. European Journal of Neuroscience. DOI
- Gendron, L., Mittal, N., Beaudry, H., Walwyn, W. (2015). Recent advances on the δ opioid receptor: From trafficking to function. British Journal of Pharmacology. DOI
- Beaudry, H., Mercier-Blais, A.-A., Delaygue, C., Lavoie, C., Parent, J.-L., Neugebauer, W., Gendron, L. (2015). Regulation of μ and δ opioid receptor functions: Involvement of cyclin-dependent kinase 5. British Journal of Pharmacology. DOI
- Thomas, J.B., Giddings, A.M., Wiethe, R.W., Olepu, S., Warner, K.R., Sarret, P., Gendron, L., Longpre, J.-M., Zhang, Y., Runyon, S.P., Gilmour, B.P. (2014). Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3- yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound. DOI
- Thomas, J.B., Giddings, A.M., Wiethe, R.W., Olepu, S., Warner, K.R., Sarret, P., Gendron, L., Longpre, J.-M., Zhang, Y., Runyon, S.P., Gilmour, B.P. (2014). Identification of N -[(5-{[(4-Methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1 H -indol-1-yl)acetyl]- l -leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2. DOI
- Desroches, J., Bouchard, J.-F., Gendron, L., Beaulieu, P. (2014). Involvement of cannabinoid receptors in peripheral and spinal morphine analgesia. DOI
- Bourassa, P., Tudashki, H.B., Pineyro, G., Grandbois, M., Gendron, L. (2014). Label-free monitoring of μ-opioid receptor-mediated signaling. DOI
- Cabañero, D., Baker, A., Zhou, S., Hargett, G.L., Irie, T., Xia, Y., Beaudry, H., Gendron, L., Melyan, Z., Carlton, S.M., Morón, J.A. (2013). Pain after discontinuation of morphine treatment is associated with synaptic increase of GluA4-containing AMPAR in the dorsal horn of the spinal cord. DOI
- Rochon, K., Proteau-Gagné, A., Bourassa, P., Nadon, J.-F., Coîté, J., Bournival, V., Gobeil, F., Guérin, B., Dory, Y.L., Gendron, L. (2013). Preparation and evaluation at the delta opioid receptor of a series of linear Leu-enkephalin analogues obtained by systematic replacement of the amides. DOI
- Normandin, A., Luccarini, P., Molat, J.-L., Gendron, L., Dallel, R. (2013). Spinal μand δ opioids inhibit both thermal and mechanical pain in rats. DOI
- Proteau-Gagné, A., Rochon, K., Roy, M., Albert, P.-J., Guérin, B., Gendron, L., Dory, Y.L. (2013). Systematic replacement of amides by 1,4-disubstituted[1,2,3]triazoles in Leu-enkephalin and the impact on the delta opioid receptor activity. DOI
- Parent, A.J., Beaudet, N., Beaudry, H., Bergeron, J., Bérubé, P., Drolet, G., Sarret, P., Gendron, L. (2012). Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain. DOI
- Maltais, J.-S., Denault, J.-B., Gendron, L., Grandbois, M. (2012). Label-free monitoring of apoptosis by surface plasmon resonance detection of morphological changes. DOI
- Beaudry, H., Dubois, D., Gendron, L. (2011). Activation of spinal μ- and δ-opioid receptors potently inhibits substance p release induced by peripheral noxious stimuli. DOI
- Proteau-Gagné, A., Nadon, J.-F., Bernard, S., Guérin, B., Gendron, L., Dory, Y.L. (2011). Kinetic deconjugation: A gateway to the synthesis of Xxx-Gly (E)-alkene dipeptide isosteres. DOI
- Bournival, V., Desjardins, R., Campbell, S., Roberge, C., Doueik, A., Gendron, L., Payet, M.D., Gallo-Payet, N., Day, R., Praud, J.-P. (2011). Presence of task-1 channel in the laryngeal mucosa in the newborn lamb. DOI
- Otis, V., Sarret, P., Gendron, L. (2011). Spinal activation of delta opioid receptors alleviates cancer-related bone pain. DOI
- Proteau-Gagne, A., St-Jean, F., Morin, C., Gendron, L., Rousseau, E., Dory, Y.L. (2011). Synthesis and functional pharmacological effects on human bronchi of 20-hydroxyeicosatetraenoic acid. DOI
- Roussy, G., Beaudry, H., Lafrance, M., Belleville, K., Beaudet, N., Wada, K., Gendron, L., Sarret, P. (2010). Altered morphine-induced analgesia in neurotensin type 1 receptor null mice. Neuroscience. DOI
- Doré-Savard, L., Otis, V., Bellevill, K., Lemire, M., Archambaul, M., Tremblay, L., Beaudoin, J.-F., Beaudet, N., Lecomte, R., Lepage, M., Gendron, L., Sarret, P. (2010). Behavioral, medical imaging and histopathological features of a new rat model of bone cancer pain. DOI
- Dubois, D., Gendron, L. (2010). Delta opioid receptor-mediated analgesia is not altered in preprotachykinin A knockout mice. DOI
- Proteau-Gagné, A., Bournival, V., Rochon, K., Dory, Y.L., Gendron, L. (2010). Exploring the backbone of enkephalins to adjust their pharmacological profile for the δ-opioid receptor. DOI
- Beaudry, H., Proteau-Gagné, A., Li, S., Dory, Y., Chavkin, C., Gendron, L. (2009). Differential noxious and motor tolerance of chronic delta opioid receptor agonists in rodents. DOI
- Sharif, N., Gendron, L., Wowchuk, J., Sarret, P., Mazella, J., Beaudet, A., Stroh, T. (2007). Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2. DOI
- Gendron, L., Pintar, J.E., Chavkin, C. (2007). Essential role of mu opioid receptor in the regulation of delta opioid receptor-mediated antihyperalgesia. DOI
- Gendron, L., Esdaile, M.J., Mennicken, F., Pan, H., O'Donnell, D., Vincent, J.-P., Devi, L.A., Cahill, C.M., Stroh, T., Beaudet, A. (2007). Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin. DOI
- Xu, M., Bruchas, M.R., Ippolito, D.L., Gendron, L., Chavkin, C. (2007). Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by κ opioid activation of p38 mitogen-activated protein kinase. DOI
- Beaudry, H., Gendron, L., Guimond, M.-O., Payet, M.D., Gallo-Payet, N. (2006). Involvement of protein kinase Cα (PKCα) in the early action of Angiotensin II type 2 (AT<inf>2</inf>) effects on neurite outgrowth in NG108-15 cells: AT<inf>2</inf>-receptor inhibits PKCα and p21<sup>ras</sup> activity. Endocrinology. DOI
- Gendron, L., Lucido, A.L., Mennicken, F., O'Donnell, D., Vincent, J.-P., Stroh, T., Beaudet, A. (2006). Morphine and pain-related stimuli enhance cell surface availability of somatic δ-opioid receptors in rat dorsal root ganglia. Journal of Neuroscience. DOI
- Perron, A., Sharif, N., Gendron, L., Lavallée, M., Stroh, T., Mazella, J., Beaudet, A. (2006). Sustained neurotensin exposure promotes cell surface recruitment of NTS2 receptors. DOI
- Perron, A., Sarret, P., Gendron, L., Stroh, T., Beaudet, A. (2005). Identification and functional characterization of a 5-transmembrane domain variant isoform of the NTS2 neurotensin receptor in rat central nervous system. DOI
- Lucido, A.L., Morinville, A., Gendron, L., Stroh, T., Beaudet, A. (2005). Prolonged morphine treatment selectively increases membrane recruitment of δ-opioid receptors in mouse basal ganglia. DOI
- Gendron, L., Perron, A., Payet, M.D., Gallo-Payet, N., Sarret, P., Beaudet, A. (2004). Low-affinity neurotensin receptor (NTS2) signaling: Internalization- dependent activation of extracellular signal-regulated kinases 1/2. DOI
- Gendron, L., Oligny, J.-F., Payet, M.D., Gallo-Payet, N. (2003). Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT<inf>2</inf> receptor signaling pathway in NG108-15 cells. Journal of Biological Chemistry. DOI
- Gendron, L., Payet, M.D., Gallo-Payet, N. (2003). The angiotensin type 2 receptor of angiotensin II and neuronal differentiation: From observations to mechanisms. DOI
- Gendron, L., Côté, F., Payet, M.D., Gallo-Payet, N. (2002). Nitric oxide and cyclic GMP are involved in angiotensin II AT<inf>2</inf> receptor effects on neurite outgrowth in NG108-15 cells. Neuroendocrinology. DOI
- Sarret, P., Gendron, L., Kilian, P., Gallo-Payet, N., Payet, M.-D., Beaudet, A. (2002). Pharmacology and functional properties of NTS2 neurotensin receptors in cerebellar granule cells. DOI
- Chorvátová, A., Gendron, L., Bilodeau, L., Gallo-Payet, N., Payet, M.D. (2000). A ras-dependent chloride current activated by adrenocorticotropin in rat adrenal zona glomerulosa cells. DOI
- Gendron, L., Laflamme, L., Rivard, N., Asselin, C., Payet, M.D., Gallo-Payet, N. (1999). Signals from the AT<inf>2</inf> (angiotensin type 2) receptor of angiotensin II inhibit p21(ras) and activate MAPK (mitogen-activated protein kinase) to induce morphological neuronal differentiation in NG108-15 cells. Molecular Endocrinology.
- Gendron, L., Laflamme, L., Asselin, C., Payet, M.D., Gallo-Payet, N. (1998). A role for p21(ras) in the angiotensin II AT<inf>2</inf> receptor transduction pathway. Endocrine Research. DOI
Livres
- Bourassa, P., Söllradl, T., Maltais, J.-S., Charette, P.G., Gendron, L., Grandbois, M. (2015). Surface plasmon resonance to study cell signaling and GPCR functional selectivity in live Cells. Methods in Pharmacology and Toxicology. DOI
Chapitres de livre
- Gendron, L., Nagi, K., Zeghal, M., Giguère, P.M., Pineyro, G. (2019). Molecular aspects of delta opioid receptors. Vitamins and Hormones. DOI
- Génier, S., Degrandmaison, J., Lavoie, C.L., Gendron, L., Parent, J.-L. (2019). Monitoring the Aggregation of GPCRs by Fluorescence Microscopy. Methods in Molecular Biology. DOI
- Abdallah, K., Gendron, L. (2018). The delta opioid receptor in pain control. Handbook of Experimental Pharmacology. DOI
- Bourassa, P., Söllradl, T., Maltais, J.-S., Charette, P.G., Gendron, L., Grandbois, M. (2015). Surface plasmon resonance to study cell signaling and gpcr functional selectivity in live cells. Label-Free Biosensor Methods in Drug Discovery. DOI
Autres contributions
Cours enseignés ou supervisés à l'UdeS
- PHR616 - Méthodes scientifiques en pharmacologie. (2024-2026). (3CR).
- PHR500 - Pharmacologie du système nerveux. (2023-2025). (3CR).
- PHR510 - Abus et dépendance. (2023-2024). (1CR).
- PHR609 - Surveillance pharmacologique et toxicologique. (2024). (3CR).
- PHR615 - Projet d'intégration en pharmacologie. (2024). (3CR).
- DOP802 - Substances et méthodes dopantes. (2023). (3CR).
