Louis-Charles Fortier

Financement

• Subvention. Demystifying virus-host interactions in Clostridioides difficile through genetic engineering of bacteriophages and the bacterial S-layer. Canadian Institutes of Health Research (Ottawa, Canada). 100 000 $. (2024-2025).
  Numéro de subvention : 202309ARB. Voir plus
• Subvention. Understanding the interplay between Shp-2 and microbiota in colonic inflammation. Canadian Institutes of Health Research (Ottawa, Canada). 994 500 $. (2023-2028).
  Numéro de subvention : 202303PJT. Voir plus
• Subvention. Développement d'une surface d'aluminium anodisé pour des applications virucides, bactéricides et sporicides. Natural Sciences and Engineering Research Council (Ottawa, Canada). 135 333 $. (2022-2023).
  Numéro de subvention : 567032-2021. Voir plus
• Subvention. Phage-host interactions in pathogenic and commensal clostridia. Natural Sciences and Engineering Research Council (Ottawa, Canada). 36 000 $. (2022-2023).
  Numéro de subvention : RGPIN-2020-05776. Voir plus
• Subvention. Replacement for Anaerobic Workstations. Natural Sciences and Engineering Research Council (Ottawa, Canada). 145 503 $. (2022-2023).
  Numéro de subvention : RTI-2023-00302. Voir plus
• Subvention. Evaluation de l'efficacite des probiotiques sur les affections post-COVID-19. Canadian Institutes of Health Research (Ottawa, Canada). 997 273 $. (2021-2022).
  Numéro de subvention : 202104GA4. Voir plus
• Subvention. L'Aluminium anodisé A3S : une surface virucide pour lutter contre la pandémie de COVID-19 dans les hôpitaux, les CHSLD, et les lieux publics. Natural Sciences and Engineering Research Council (Ottawa, Canada). 50 000 $. (2020-2021).
  Numéro de subvention : 554629-2020. Voir plus
• Subvention. Epithelial-specific role of SOCS1 in prevention of intestinal inflammation. Canadian Institutes of Health Research (Ottawa, Canada). 827 386 $. (2019-2024).
  Numéro de subvention : 201809PJT. Voir plus
• Subvention. 69th Annual Conference of the Canadian Society of Microbiologists (CSM 2019) - One Health-related symposia. Canadian Institutes of Health Research (Ottawa, Canada). 10 000 $. (2018-2019).
  Numéro de subvention : 201809PCS. Voir plus
• Subvention. Initial vancomycin taper for the prevention of recurrent Clostridium difficile infection. Canadian Institutes of Health Research (Ottawa, Canada). 398 423 $. (2018-2020).
  Numéro de subvention : 201803PJT. Voir plus
• Subvention. Isolation and characterization of Clostridium perfringens lytic phages for veterinary applications in the poultry industry. Natural Sciences and Engineering Research Council (Ottawa, Canada). 25 000 $. (2018-2019).
  Numéro de subvention : 529295-2018. Voir plus
• Subvention. Replacement for Microbial Growth Assay Cluster. Natural Sciences and Engineering Research Council (Ottawa, Canada). 143 350 $. (2018-2019).
  Numéro de subvention : RTI-2019-00596. Voir plus
• Subvention. Replacement for Fast Protein Liquid Chromatography System. Natural Sciences and Engineering Research Council (Ottawa, Canada). 138 000 $. (2017-2018).
  Numéro de subvention : RTI-2018-00630. Voir plus
• Subvention. Étude des mécanismes d'action anti-Clostridium difficile par le probiotique Bio-K+. Natural Sciences and Engineering Research Council (Ottawa, Canada). 12 500 $. (2015-2016).
  Numéro de subvention : 478094-2015. Voir plus
• Subvention. Phage biology and diversity in Clostridium difficile and other commensal clostridia. Natural Sciences and Engineering Research Council (Ottawa, Canada). 150 000 $. (2015-2020).
  Numéro de subvention : RGPIN-2015-06334. Voir plus
• Subvention. Étude des mécanismes d'action anti-Clostridium difficile par le probiotique Bio-K+. Natural Sciences and Engineering Research Council (Ottawa, Canada). 25 000 $. (2014-2015).
  Numéro de subvention : 468586-2014. Voir plus
• Subvention. Modulation de l’expression génique par les riborégulateurs: mécanisme d’action et rôle dans la biologie et la virulence de Clostridium difficile. Fonds de Recherche du Québec – Nature et Technologies (Montreal, Canada). 177 222 $. (2014-2017).
  Numéro de subvention : 183241. Voir plus
• Subvention. Développement d'anticorps spécifiques dirigés contre des protéines de surface des bactéries et des spores de Clostridium difficile et ses toxines. Natural Sciences and Engineering Research Council (Ottawa, Canada). 24 995 $. (2013-2014).
  Numéro de subvention : 452900-2013. Voir plus
• Subvention. Pathogénèse des infections à Clostridium difficile, interactions hôte-pathogène et développement d'agents thérapeutiques novateurs. Fonds de Recherche du Québec - Santé (Montreal, Canada). 295 451 $. (2012-2016).
  Numéro de subvention : 25144. Voir plus
• Subvention. Phage biology and diversity in Clostridium difficile. Natural Sciences and Engineering Research Council (Ottawa, Canada). 135 000 $. (2010-2015).
  Numéro de subvention : 341450-2010. Voir plus
• Subvention. Plateform for studying virulence factors in anaerobic pathogens and for the development of phage-based therapeutic agents. Canada Foundation for Innovation (Ottawa, Canada). 80 276 $. (2009).
  Numéro de subvention : 24261. Voir plus
• Subvention. Étude moléculaire des bactériophages infectant Clostridium difficile et développement d alternatives thérapeutiques pour traiter la diarrhée associée à C. difficile (DACD). Fonds de Recherche du Québec - Santé (Montreal, Canada). 30 000 $. (2008-2011).
  Numéro de subvention : 5854. Voir plus
• Subvention. Étude moléculaire des bactériophages infectant Clostridium difficile et développement d alternatives thérapeutiques pour traiter la diarrhée associée à C. difficile (DACD). Fonds de Recherche du Québec - Santé (Montreal, Canada). 196 691 $. (2008-2012).
  Numéro de subvention : 14301. Voir plus
• Subvention. Development of phage therapy and phage-derived therapeutic molecules to treat Clostridium difficile-associated diarrhea. Canadian Institutes of Health Research (Ottawa, Canada). 195 600 $. (2007-2009).
  Numéro de subvention : 200609XNO. Voir plus
• Subvention. Culture, molecular typing, and phylogenetic analysis of pathogenic bacteria. Natural Sciences and Engineering Research Council (Ottawa, Canada). 31 500 $. (2007-2008).
  Numéro de subvention : grant.2864929. Voir plus
• Subvention. Characterization of mobile genetic elements from clostridium difficile and development of molecular tools for genetic manipulations. Natural Sciences and Engineering Research Council (Ottawa, Canada). 72 510 $. (2007-2010).
  Numéro de subvention : grant.2933162. Voir plus

Publications

Articles

• Alexia L.M. Royer, Émeline Dion, Andrew A. Umansky, Mariano Avino, Olga Soutourina, Louis-Charles Fortier. (2025). Structural determinants of SlpA-mediated phage recognition in Clostridioides difficile. PLOS Pathogens. DOI
• Marion Saunier, Adeline Humbert, Victor Kreis, Johann Peltier, Arianna Tisba, Sylvie Auxilien, Marion Blum, Isabelle Caldelari, Jean-François Lucier, Joe Ueda, Daniel Gautheret, Claire Toffano-Nioche, Jessica Andreani, Louis-Charles Fortier, Olga Soutourina. (2025). Deciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile. PLOS Genetics. DOI
• Jason S Wilson, Louis-Charles Fortier, Robert P Fagan, Per A Bullough. (2025). Molecular mechanism of bacteriophage contraction structure of an S-layer–penetrating bacteriophage. Life Science Alliance. DOI
• (2025). Deciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile. bioRxiv. DOI
• Dong Q, Harper S, McSpadden E, Son SS, Allen MM, Lin H, Smith RC, Metcalfe C, Burgo V, Woodson C, Sundararajan A, Rose A, McMillin M, Moran D, Little J, Mullowney MW, Sidebottom AM, Fortier LC, Shen A, Pamer EG. (2024). Protection against Clostridioides difficile disease by a naturally avirulent strain. Cell host & microbe. DOI
• Saunier M, Fortier LC, Soutourina O. (2024). RNA-based regulation in bacteria-phage interactions. Anaerobe. DOI
• Marie-Félixe Granger, Mirabelle Kelly, Louis-Charles Fortier, Eric Fournier, Julie Côté-Gravel, François Malouin, Louis Valiquette, Simon Lévesque. (2023). Chronic Diarrhea Caused by a <i>Klebsiella oxytoca</i> Toxin Producer Strain Following Antibiotic-Associated Hemorrhagic Colitis: Successful Treatment by Fecal Microbiota Transplant. Clinical Infectious Diseases. DOI
• Taki Aissou, Jessica Jann, Nathalie Faucheux, Louis-Charles Fortier, Nadi Braidy, Jocelyn Veilleux. (2023). Suspension plasma sprayed copper-graphene coatings for improved antibacterial properties. Applied Surface Science. DOI
• Andrew A. Umansky, Louis Charles Fortier. (2023). The long and sinuous road to phage-based therapy of Clostridioides difficile infections. Frontiers in Medicine. DOI
• Qiwen Dong, Huaiying Lin, Marie-Maude Allen, Julian R. Garneau, Jonathan K. Sia, Rita C. Smith, Fidel Haro, Tracy McMillen, Rosemary L. Pope, Carolyn Metcalfe, Victoria Burgo, Che Woodson, Nicholas Dylla, Claire Kohout, Anitha Sundararajan, Evan S. Snitkin, Vincent B. Young, Louis-Charles Fortier, Mini Kamboj, Eric G. Pamer. (2023). Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile. Cell Reports. DOI
• Jessica Jann, Suzanne Gascon, Olivier Drevelle, Julie Fradette, Myriam Auclair-Gilbert, Gervais Soucy, Louis-Charles Fortier, Nathalie Faucheux. (2023). Assessment of antibacterial properties and skin irritation potential of anodized aluminum impregnated with various quaternary ammonium. Biomaterials Advances. DOI
• Jennifer Valdes, Jessica Gagné‐Sansfaçon, Vilcy Reyes, Anny Armas, Gisela Marrero, Mitterrand Moyo‐Muamba, Sheela Ramanathan, Nathalie Perreault, Subburaj Ilangumaran, Nathalie Rivard, Louis‐Charles Fortier, Alfredo Menendez. (2023). Defects in the expression of colonic host defense factors associate with barrier dysfunction induced by a high‐fat/high‐cholesterol diet. The Anatomical Record. DOI
• Alicia Molina Kautzman, Jeanne Masunga Faida Mobulakani, Gisela Marrero Cofino, Akouavi Julite Irmine Quenum, Anny Armas Cayarga, Claude Asselin, Louis‐Charles Fortier, Subburaj Ilangumaran, Alfredo Menendez, Sheela Ramanathan. (2023). Interleukin 15 in murine models of colitis. The Anatomical Record. DOI
• Alexia L. M. Royer, Andrew A. Umansky, Marie-Maude Allen, Julian R. Garneau, Maicol Ospina-Bedoya, Joseph A. Kirk, Gregory Govoni, Robert P. Fagan, Olga Soutourina, Louis-Charles Fortier. (2023). Clostridioides difficile S-Layer Protein A (SlpA) Serves as a General Phage Receptor. Microbiology Spectrum. DOI
• Julian R. Garneau, Véronique Legrand, Martial Marbouty, Maximilian O. Press, Dean R. Vik, Louis-Charles Fortier, Matthew B. Sullivan, David Bikard, Marc Monot. (2022). Author Correction: High-throughput identification of viral termini and packaging mechanisms in virome datasets using PhageTermVirome. Scientific Reports. DOI
• Erich Smith-Peter, David Lalonde Séguin, Émilie St-Pierre, Ognjen Sekulovic, Simon Jeanneau, Cédrick Tremblay-Tétreault, Anne-Marie Lamontagne, Pierre-Étienne Jacques, Daniel A. Lafontaine, Louis-Charles Fortier. (2021). Inactivation of the riboswitch-controlled GMP synthase GuaA in Clostridioides difficile is associated with severe growth defects and poor infectivity in a mouse model of infection. RNA Biology. DOI
• Julian R. Garneau, Véronique Legrand, Martial Marbouty, Maximilian O. Press, Dean R. Vik, Louis-Charles Fortier, Matthew B. Sullivan, David Bikard, Marc Monot. (2021). High-throughput identification of viral termini and packaging mechanisms in virome datasets using PhageTermVirome. Scientific Reports. DOI
• Joshua Heuler, Louis-Charles Fortier, Xingmin Sun. (2021). <i>Clostridioides difficile</i> phage biology and application. FEMS Microbiology Reviews. DOI
• Marie-Elisabeth Bouchard, Eric Rousseau, Louis-Charles Fortier, Isabelle Girard. (2021). Pathophysiology of Vaginal Erosions in Women Using Pessary: A Pilot Study Examining Vaginal Microbiota. Journal of Obstetrics and Gynaecology Canada. DOI
• Jessica Jann, Olivier Drevelle, X. Grant Chen, Myriam Auclair-Gilbert, Gervais Soucy, Nathalie Faucheux, Louis-Charles Fortier. (2021). Rapid antibacterial activity of anodized aluminum-based materials impregnated with quaternary ammonium compounds for high-touch surfaces to limit transmission of pathogenic bacteria. RSC Advances. DOI
• Johann Peltier, Audrey Hamiot, Julian R. Garneau, Pierre Boudry, Anna Maikova, Eliane Hajnsdorf, Louis-Charles Fortier, Bruno Dupuy, Olga Soutourina. (2020). Type I toxin-antitoxin systems contribute to the maintenance of mobile genetic elements in Clostridioides difficile. Communications Biology. DOI
• Selle K, Fletcher JR, Tuson H, Schmitt DS, McMillan L, Vridhambal GS, Rivera AJ, Montgomery SA, Fortier LC, Barrangou R, Theriot CM, Ousterout DG. (2020). <i>In Vivo</i> Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials. mBio. DOI
• Garneau, J.R., Chakra, C.N.A., Fortier, L.-C., Labbé, A.-C., Simor, A.E., Gold, W., Muller, M., McGeer, A., Powis, J., Katz, K., Pépin, J., Valiquette, L. (2019). Multilocus variable-number tandem-repeat analysis of clostridioides difficile clusters in ribotype 027 isolates and lack of association with clinical outcomes. Journal of Clinical Microbiology. DOI
• (2019). PATHOPHYSIOLOGY OF ULCERATION IN WOMEN USING A PESSARY: AN EXPERIMENTAL APPROACH. INTERNATIONAL UROGYNECOLOGY JOURNAL.
• Fortier, L.-C. (2018). Bacteriophages contribute to shaping clostridioides (Clostridium) difficile species. Frontiers in Microbiology. DOI
• Carignan, A., Fortier, L.-C. (2018). Discovery of keyicin, a new antibiotic: It takes two to tango,La keyicine. Medecine/Sciences. DOI
• Yan, L.-H., Le Roux, A., Boyapelly, K., Lamontagne, A.-M., Archambault, M.-A., Picard-Jean, F., Lalonde-Seguin, D., St-Pierre, E., Najmanovich, R.J., Fortier, L.-C., Lafontaine, D., Marsault, É. (2018). Purine analogs targeting the guanine riboswitch as potential antibiotics against Clostridioides difficile. European Journal of Medicinal Chemistry. DOI
• Julian R. Garneau, Ognjen Sekulovic, Bruno Dupuy, Olga Soutourina, Marc Monot, Louis-Charles Fortier. (2017). High prevalence and genetic diversity of large phiCD211/phiCDIF1296T-like prophages inClostridioides difficile. Applied and Environmental Microbiology. DOI
• Sarah Tremblay, Nathalie Marie Louise Côté, Guillaume Grenier, Gabriella Duclos-Lasnier, Louis-Charles Fortier, Subburaj Ilangumaran, Alfredo Menendez. (2017). Ileal antimicrobial peptide expression is dysregulated in old age. Immunity & Ageing. DOI
• Julian R. Garneau, Florence Depardieu, Louis-Charles Fortier, David Bikard, Marc Monot. (2017). PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data. Scientific Reports. DOI
• Jean-Charles Pasquier, Antoine Lewin, Émilie St Pierre, Virginie Gillet, Louis-Charles Fortier. (2017). 444: Fecal transplants disturb length of pregnancy in a mouse model. American Journal of Obstetrics and Gynecology. DOI
• Marie-Julie Allard, Julie D. Bergeron, Moogeh Baharnoori, Lalit K. Srivastava, Louis-Charles Fortier, Claire Poyart, Guillaume Sébire. (2016). A sexually dichotomous, autistic-like phenotype is induced by Group B Streptococcus maternofetal immune activation. Autism Research. DOI
• Bergeron, J., Gerges, N., Guiraut, C., Grbic, D., Allard, M.-J., Fortier, L.-C., Vaillancourt, C., Sébire, G. (2016). Activation of the IL-1β/CXCL1/MMP-10 axis in chorioamnionitis induced by inactivated Group B Streptococcus. Placenta. DOI
• (2016). End-Gestational Group B Streptococcus Infection: Sex Dichotomic Chorioamnionitis and Autistic-Like Traits in Male Offspring. REPRODUCTIVE SCIENCES.
• (2016). Involvement of the IL-1β/PMN/MMP-10 Axis in Group B Streptococcus-Induced Chorioamnionitis. REPRODUCTIVE SCIENCES.
• Pierre Boudry, Ekaterina Semenova, Marc Monot, Kirill A. Datsenko, Anna Lopatina, Ognjen Sekulovic, Maicol Ospina-Bedoya, Louis-Charles Fortier, Konstantin Severinov, Bruno Dupuy, Olga Soutourina. (2015). Erratum for Boudry et al., Function of the CRISPR-Cas System of the Human PathogenClostridium difficile. mBio. DOI
• Pierre Boudry, Ekaterina Semenova, Marc Monot, Kirill A. Datsenko, Anna Lopatina, Ognjen Sekulovic, Maicol Ospina-Bedoya, Louis-Charles Fortier, Konstantin Severinov, Bruno Dupuy, Olga Soutourina. (2015). Function of the CRISPR-Cas System of the Human PathogenClostridium difficile. mBio. DOI
• Ognjen Sekulovic, Maicol Ospina Bedoya, Amanda S. Fivian-Hughes, Neil F. Fairweather, Louis-Charles Fortier. (2015). TheClostridium difficilecell wall protein CwpV confers phase-variable phage resistance. Molecular Microbiology. DOI
• (2015). Exposition to group B streptococcal maternal inflammation: White matter injury and autistic-like behavior predominantly affecting male rat offspring. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. DOI
• Abou Chakra, C.N., McGeer, A., Labbe, A.-C., Simor, A.E., Gold, W.L., Muller, M.P., Powis, J., Katz, K., Garneau, J.R., Fortier, L.-C., Pepin, J., Cadarette, S.M., Valiquette, L. (2015). Factors Associated with Complications of Clostridium difficile Infection in a Multicenter Prospective Cohort. Clinical Infectious Diseases. DOI
• (2015). Group B streptococcus infection during gestation induces gender specific neurodevelopmental impairments. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. DOI
• Claire Nour Abou Chakra, Allison Mcgeer, Annie-Claude Labbé, Andrew E. Simor, Wayne Gold, Matthew P. Muller, Jeff Powis, Kevin Katz, Julian R. Garneau, Louis-Charles Fortier, Jacques Pepin, Louis Valiquette. (2015). Independent Risk Factors for Recurrence of Clostridium difficile Infection: A Canadian Multicenter Prospective Cohort. Open Forum Infectious Diseases. DOI
• Sekulovic, O., Garneau, J.R., Néron, A., Fortier, L.-C. (2014). Characterization of temperate phages infecting Clostridium difficile isolates of human and animal origins. Applied and Environmental Microbiology. DOI
• Eric Bordeleau, Erin B. Purcell, Daniel A. Lafontaine, Louis-Charles Fortier, Rita Tamayo, Vincent Burrus. (2014). Cyclic Di-GMP Riboswitch-Regulated Type IV Pili Contribute to Aggregation of Clostridium difficile. Journal of Bacteriology. DOI
• Ognjen Sekulovic, Louis-Charles Fortier. (2014). Global Transcriptional Response of Clostridium difficile Carrying the ϕCD38-2 Prophage. Applied and Environmental Microbiology. DOI
• (2014). Prevention of <i>Clostridium difficile</i> spore formation by sub-inhibitory concentrations of tigecycline and piperacillin/tazobactam. BMC INFECTIOUS DISEASES. DOI
• (2013). Importance of prophages to evolution and virulence of bacterial pathogens. VIRULENCE. DOI
• (2013). White Matter Injury and Autistic-Like Behavior Predominantly Affecting Male Rat Offspring Exposed to Group B Streptococcal Maternal Inflammation. DEVELOPMENTAL NEUROSCIENCE. DOI
• (2012). Evidence of <i>In Vivo</i> Prophage Induction during <i>Clostridium difficile</i> Infection. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. DOI
• (2012). Novel High-Molecular-Weight, R-Type Bacteriocins of <i>Clostridium difficile</i>. JOURNAL OF BACTERIOLOGY. DOI
• (2011). Lack of Association between Clinical Outcome of <i>Clostridium difficile</i> Infections, Strain Type, and Virulence-Associated Phenotypes. JOURNAL OF CLINICAL MICROBIOLOGY. DOI
• (2011). Prophage-Stimulated Toxin Production in <i>Clostridium difficile</i> NAP1/027 Lysogens. JOURNAL OF BACTERIOLOGY. DOI
• (2011). Role of of gestational inflammation induced by group B streptococcus in perinatal brain lesions and subsequent cerebral palsy. ANNALS OF NEUROLOGY.
• (2011). c-di-GMP Turn-Over in <i>Clostridium difficile</i> Is Controlled by a Plethora of Diguanylate Cyclases and Phosphodiesterases. PLOS GENETICS. DOI
• (2010). Faecal pharmacokinetics of orally administered vancomycin in patients with suspected <i>Clostridium difficile</i> infection. BMC INFECTIOUS DISEASES. DOI
• (2010). Novel Riboswitch Ligand Analogs as Selective Inhibitors of Guanine-Related Metabolic Pathways. PLOS PATHOGENS. DOI
• Mulhbacher, J., Brouillette, E., Allard, M., Fortier, L.-C., Malouin, F., Lafontaine, D.A. (2010). Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways. PLoS Pathogens.
• (2009). Antiapoptotic Proteins Bcl-2 and Bcl-X_L Inhibit <i>Clostridium difficile</i> Toxin A-Induced Cell Death in Human Epithelial Cells. INFECTION AND IMMUNITY. DOI
• Fortier, L.C., Moineau, S. (2009). Phage production and maintenance of stocks, including expected stock lifetimes. Methods in molecular biology (Clifton, N.J.).
• (2008). AbiV, a Novel Antiphage Abortive Infection Mechanism on the Chromosome of <i>Lactococcus lactis</i> subsp <i>cremoris</i> MG1363. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. DOI
• (2007). Morphological and genetic diversity of temperate phages in <i>Clostridium difficile</i>. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. DOI
• (2006). Genome sequence and global gene expression of Q54, a new phage species linking the 936 and c2 phage species of <i>Lactococcus lactis</i>. JOURNAL OF BACTERIOLOGY. DOI
• (2006). The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver. DRUG METABOLISM AND DISPOSITION. DOI
• (2005). Expression and site-directed mutagenesis of the lactococcal abortive phage infection protein AbiK. JOURNAL OF BACTERIOLOGY. DOI
• (2005). UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver. HEPATOLOGY. DOI
• (2004). Identification of common polymorphisms in the promoter of the UGT1A9 gene: Evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver. DRUG METABOLISM REVIEWS.
• (2004). Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver. PHARMACOGENETICS. DOI
• (2004). UGT1A1 promoter polymorphism as an important determinant of heterocyclic amine detoxification. DRUG METABOLISM REVIEWS.
• (2003). Induction of <i>Oenococcus oeni</i> H<SUP>+</SUP>-ATPase activity and mRNA transcription under acidic conditions. FEMS MICROBIOLOGY LETTERS. DOI
• (2003). Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. DOI
• (2002). Acidophilic behaviour of the malolactic bacterium <i>Oenococcus oeni</i>. SCIENCES DES ALIMENTS. DOI
• (2000). Regulation of stress response in <i>Oenococcus oeni</i> as a function of environmental changes and growth phase. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY. DOI
• (1999). Acid sensitivity of neomycin-resistant mutants of <i>Oenococcus oeni</i>: a relationship between reduction of ATPase activity and lack of malolactic activity. FEMS MICROBIOLOGY LETTERS. DOI
• Tourdot-Maréchal, R., Fortier, L.-C., Guzzo, J., Lee, B., Diviès, C. (1999). Acid sensitivity of neomycin-resistant mutants of Oenococcus oeni: A relationship between reduction of ATPase activity and lack of malolactic activity. FEMS Microbiology Letters. DOI
• (1998). Rescue of polyomavirus DNA after co-transfection of recombinant plasmids with viral DNA fragments. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION. DOI

Autres contributions

Cours enseignés ou supervisés à l'UdeS

• VIR516 - Projet en virologie. (2025-2026). (1CR).
• MCB103 - Microbiologie en pharmacologie - Travaux pratiques. (2023-2025). (3CR).
• VIR515 - Virologie - Travaux pratiques. (2023-2024). (1CR).

Divers

• Julian R Garneau, Florence Depardieu, Louis-Charles Fortier, David Bikard, Marc Monot. (2017). PhageTerm: a Fast and User-friendly Software to Determine Bacteriophage Termini and Packaging Mode using randomly fragmented NGS data.
• Louis-Charles Fortier. (2017). The Contribution of Bacteriophages to the Biology and Virulence of Pathogenic Clostridia. Advances in Applied Microbiology.
• Ognjen Sekulović, Louis-Charles Fortier. (2016). Characterization of Functional Prophages in Clostridium difficile. Clostridium difficile.
• Louis-Charles Fortier, Sylvain Moineau. (2009). Phage Production and Maintenance of Stocks, Including Expected Stock Lifetimes. Bacteriophages.