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Karine Tremblay

Professeure, Faculté de médecine et des sciences de la santé
FMSS Département de pharmacologie-physiologie

Présentation

Expériences académiques

  • Assistant Professor (Pharmacology-physiology). (2020-). Université de Sherbrooke. Sherbrooke, QC, Canada.

Publications

Articles

  • Rusan Lateef, Jacinthe Dion, Karine Tremblay, Isabelle Daigneault, Martine Hébert, Annie Lemieux, Geneviève Paquette. (2026). Exploring the indirect pathways between service involvement, unmet service needs, parental distress, and the maltreatment of children with intellectual disabilities. International Journal of Developmental Disabilities. DOI
  • Sophie St-Amour, Laurence Tessier, Janie Harnois, Catherine Allard, Alexandre Lavoie, Philippe Caron, Luigi Bouchard, Patrice Perron, Karine Tremblay. (2025). PCK1 and SLC22A2 gene variants associated with response to metformin treatment in type 2 diabetes. PLOS ONE. DOI
  • William Bourumeau, Karine Tremblay, Guillaume Jourdan, Catherine Girard, Catherine Laprise. (2023). Bacterial Biomarkers of the Oropharyngeal and Oral Cavity during SARS-CoV-2 Infection. Microorganisms. DOI
  • Justine Benoit-Piau, Karine Tremblay, Alain Piché, Frédéric Dallaire, Mathieu Bélanger, Marc-André d’Entremont, Jean-Charles Pasquier, Martin Fortin, Catherine Bourque, Fanny Lapointe, Jean-François Betala-Belinga, Geneviève Petit, Guillaume Jourdan, Renata Bahous, Camilo Maya, Amira Benzina, Muhammad Faiyaz Hossain, Marie-Audrey Peel, Olivier Houle, ... Paul Farand. (2023). Long-Term Consequences of COVID-19 in Predominantly Immunonaive Patients: A Canadian Prospective Population-Based Study. Journal of Clinical Medicine. DOI
  • Ann-Lorie Gagnon, William Beauchesne, Laurence Tessier, Charles David, Djamal Berbiche, Alexandre Lavoie, Alban Michaud-Herbst, Karine Tremblay. (2021). Adalimumab, Infliximab, and Vedolizumab in Treatment of Ulcerative Colitis: A Long-Term Retrospective Study in a Tertiary Referral Center. Crohn's & Colitis 360. DOI
  • Ann-Lorie Gagnon, Alexandre Lavoie, Marie-Pier Frigon, Alban Michaud-Herbst, Karine Tremblay. (2020). A Drug-Induced Acute Pancreatitis Retrospective Study. Canadian Journal of Gastroenterology and Hepatology. DOI
  • (2020). Gene expression profiles of recurrent acute pancreatitis risk in patients with sustained chylomicronemia. Endocrine journal. DOI
  • Tremblay, K., Gaudet, D., Khoury, E., Brisson, D. (2020). Dissection of Clinical and Gene Expression Signatures of Familial versus Multifactorial Chylomicronemia. Journal of the Endocrine Society. DOI
  • Gagnon, A.-L., Frigon, M.-P., Tremblay, K. (2020). Hospitalizations for Acute and Chronic Pancreatitis in a French-Canadian Population. Pancreas. DOI
  • Marie-Pier Frigon, Marie-Ève Blackburn, Camélia Dubois-Bouchard, Ann-Lorie Gagnon, Suzie Tardif, Karine Tremblay. (2019). Pharmacogenetic Testing in Primary Care Practice: Opinions of Physicians, Pharmacists and Patients. Pharmacogenomics. DOI
  • Dron, J.S., Wang, J., Berberich, A.J., Iacocca, M.A., Cao, H., Yang, P., Knoll, J., Tremblay, K., Brisson, D., Netzer, C., Gouni-Berthold, I., Gaudet, D., Hegele, R.A. (2018). Large-scale deletions of the ABCA1 gene in patients with hypoalphalipoproteinemia. Journal of Lipid Research. DOI
  • Gaudet, D., Stroes, E.S., Méthot, J., Brisson, D., Tremblay, K., Bernelot Moens, S.J., Iotti, G., Rastelletti, I., Ardigo, D., Corzo, D., Meyer, C., Andersen, M., Ruszniewski, P., Deakin, M., Bruno, M.J. (2016). Long-term retrospective analysis of gene therapy with Alipogene Tiparvovec and its effect on lipoprotein lipase deficiency-induced pancreatitis. Human Gene Therapy. DOI
  • Gaudet, D., Alexander, V.J., Baker, B.F., Brisson, D., Tremblay, K., Singleton, W., Geary, R.S., Hughes, S.G., Viney, N.J., Graham, M.J., Crooke, R.M., Witztum, J.L., Brunzell, J.D., Kastelein, J.J.P. (2015). Antisense inhibition of apolipoprotein C-III in patients with hypertriglyceridemia. New England Journal of Medicine. DOI
  • Meyers, C.D., Tremblay, K., Amer, A., Chen, J., Jiang, L., Gaudet, D. (2015). Effect of the DGAT1 inhibitor pradigastat on triglyceride and apoB48 levels in patients with familial chylomicronemia syndrome. Lipids in Health and Disease. DOI
  • Tremblay, K., Dubois-Bouchard, C., Brisson, D., Gaudet, D. (2014). Association of CTRC and SPINK1 gene variants with recurrent hospitalizations for pancreatitis or acute abdominal pain in lipoprotein lipase deficiency. Frontiers in Genetics. DOI
  • Gaudet, D., Brisson, D., Tremblay, K., Alexander, V.J., Singleton, W., Hughes, S.G., Geary, R.S., Baker, B.F., Graham, M.J., Crooke, R.M., Witztum, J.L. (2014). Targeting APOC3 in the familial chylomicronemia syndrome. New England Journal of Medicine. DOI
  • Gaudet, D., Méthot, J., Déry, S., Brisson, D., Essiembre, C., Tremblay, G., Tremblay, K., De Wal, J., Twisk, J., Van Den Bulk, N., Sier-Ferreira, V., Van Deventer, S. (2013). Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPL S447X) gene therapy for lipoprotein lipase deficiency: An open-label trial. Gene Therapy. DOI
  • Gaudet, D., Signorovitch, J., Swallow, E., Fan, L., Tremblay, K., Brisson, D., Meyers, C., Gruenberger, J.-B. (2013). Medical resource use and costs associated with chylomicronemia. Journal of Medical Economics. DOI
  • Loucif, Y., Méthot, J., Tremblay, K., Brisson, D., Gaudet, D. (2011). Contribution of adiponectin to the cardiometabolic risk of postmenopausal women with loss-of-function lipoprotein lipase gene mutations. Menopause. DOI
  • Tremblay, K., Méthot, J., Brisson, D., Gaudet, D. (2011). Etiology and risk of lactescent plasma and severe hypertriglyceridemia. Journal of Clinical Lipidology. DOI
  • Brisson, D., Méthot, J., Tremblay, K., Tremblay, M., Perron, P., Gaudet, D. (2010). Comparison of the efficacy of fibrates on hypertriglyceridemic phenotypes with different genetic and clinical characteristics. Pharmacogenetics and Genomics. DOI
  • Gaudet, D., de Wal, J., Tremblay, K., Déry, S., van Deventer, S., Freidig, A., Brisson, D., Méthot, J. (2010). Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency. Atherosclerosis Supplements. DOI
  • Chamberland, A., Madore, A.-M., Tremblay, K., Laviolette, M., Laprise, C. (2009). A comparison of two sets of microarray experiments to define allergic asthma expression pattern. Experimental Lung Research. DOI
  • Tremblay, K., Laprise, C. (2009). Genetics of respiratory diseases: Example of cystic fibrosis and asthma,Génétique des maladies respiratoires : L'exemple de la fibrose kystique et de l'asthme. Revue des Maladies Respiratoires Actualites. DOI
  • Tremblay, K., Lemire, M., Potvin, C., Tremblay, A., Hunninghake, G.M., Raby, B.A., Hudson, T.J., Perez-Iratxeta, C., Andrade-Navarro, M.A., Laprise, C. (2008). Genes to diseases (G2D) computational method to identify asthma candidate genes. PLoS ONE. DOI
  • Tremblay, K., Daley, D., Chamberland, A., Lemire, M., Montpetit, A., Laviolette, M., Musk, A.W., James, A.L., Chan-Yeung, M., Becker, A., Kozyrskyj, A.L., Sandford, A.J., Hudson, T.J., Paré, P.D., Laprise, C. (2008). Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues. Journal of Allergy and Clinical Immunology. DOI
  • Madore, A.-M., Tremblay, K., Hudson, T.J., Laprise, C. (2008). Replication of an association between 17q21 SNPs and asthma in a French-Canadian familial collection. Human Genetics. DOI
  • Bégin, P., Tremblay, K., Daley, D., Lemire, M., Claveau, S., Salesse, C., Kacel, S., Montpetit, A., Becker, A., Chan-Yeung, M., Kozyrskyj, A.L., Hudson, T.J., Laprise, C. (2007). Association of urokinase-type plasminogen activator with asthma and atopy. American Journal of Respiratory and Critical Care Medicine. DOI
  • Tremblay, K., Lemire, M., Provost, V., Pastinen, T., Renaud, Y., Sandford, A.J., Laviolette, M., Hudson, T.J., Laprise, C. (2006). Association study between the CX3CR1 gene and asthma. Genes and Immunity. DOI

Autres contributions

Cours enseignés ou supervisés à l'UdeS

  • BIM503 - Pharmacogénétique et pharmacogénomique. (2025). (2CR).