François Bachand
Professeur, Faculté de médecine et des sciences de la santé
FMSS Département de biochimie et de génomique fonctionnelle
Présentation
Publications
Articles
- Zabih Mir Hassani, Frédérique Goulet, Duc Tai Nguyen, Anne-Marie Landry-Voyer, Lauren Kwiatek, Shany Gaudet, Pierre-Luc Boudreault, Taha Azad, François Bachand. (2026). Biosensor-guided discovery of peptide inhibitors targeting the ribosomal protein uS5-PDCD2 chaperone interaction. Journal of Biological Chemistry. DOI
- Valérie Migeot, Yves Mary, Etienne Fafard-Couture, Pierre Lombard, François Bachand, Michelle S Scott, Carlo Yague-Sanz. (2025). RNase III cleavage sites spread across splice junctions enforce sequential snoRNA processing. EMBO Reports. DOI
- Anne-Marie Landry-Voyer, Tess Holling, Emily K. Mis, Zabih Mir Hassani, Malik Alawi, Weizhen Ji, Lauren Jeffries, Kerstin Kutsche, François Bachand, Saquib A. Lakhani. (2025). Biallelic variants in the conserved ribosomal protein chaperone gene PDCD2 are associated with hydrops fetalis and early pregnancy loss. Proceedings of the National Academy of Sciences. DOI
- Mélodie Latour, Lauren Kwiatek, Anne-Marie Landry-Voyer, François Bachand. (2025). Antagonistic roles by the conserved nuclear poly(A)-binding proteins PABPN1 and ZC3H14 in nuclear RNA surveillance. Nucleic Acids Research. DOI
- Cédric Boulanger, Nouhou Haidara, Carlo Yague-Sanz, Marc Larochelle, Pierre-Étienne Jacques, Damien Hermand, Francois Bachand. (2024). Repression of pervasive antisense transcription is the primary role of fission yeast RNA polymerase II CTD serine 2 phosphorylation. Nucleic Acids Research. DOI
- Maxime Duval, Carlo Yague-Sanz, Tomasz W. Turowski, Elisabeth Petfalski, David Tollervey, François Bachand. (2023). The conserved RNA-binding protein Seb1 promotes cotranscriptional ribosomal RNA processing by controlling RNA polymerase I progression. Nature Communications. DOI
- Anne-Marie Landry-Voyer, Zabih Mir Hassani, Mariano Avino, François Bachand. (2023). Ribosomal Protein uS5 and Friends: Protein–Protein Interactions Involved in Ribosome Assembly and Beyond. Biomolecules. DOI
- Lauren Kwiatek, Anne-Marie Landry-Voyer, Mélodie Latour, Carlo Yague-Sanz, Francois Bachand. (2023). PABPN1 prevents the nuclear export of an unspliced RNA with a constitutive transport element and controls human gene expression via intron retention. RNA. DOI
- Carlo Yague-Sanz, Maxime Duval, Marc Larochelle, François Bachand. (2021). Co-transcriptional RNA cleavage by Drosha homolog Pac1 triggers transcription termination in fission yeast. Nucleic Acids Research. DOI
- Anne-Marie Landry-Voyer, Danny Bergeron, Carlo Yague-Sanz, Breac Baker, Francois Bachand. (2020). PDCD2 functions as an evolutionarily conserved chaperone dedicated for the 40S ribosomal protein uS5 (RPS2). Nucleic Acids Research. DOI
Autres contributions
Cours enseignés ou supervisés à l'UdeS
- BCM632 - Génomique et protéomique. (2024, 2026). (3CR).