Fabrice Jean-Pierre
Professeur, Faculté des sciences
FSCI Département de biologie
Présentation
Sujets, disciplines ou intérêts de recherche
Polymicrobial communities, Bacterial biofilms, Interspecies interactions, Antimicrobial resistance and tolerance, Chronic infections, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus, Anaerobes
Diplômes
- (2011-2017). Ph.D. INRS-Institut Armand-Frappier. Laval, QC, Canada.
- (2008-2011). Bachelor of Science. Microbiology & Immunology. McGill University. Montreal, Quebec, Canada.
Expériences académiques
- Assistant Professor. (2024-). Université de Sherbrooke. Sherbrooke, QC, Canada.
- Postdoctoral Fellow. (2019-2023). Dartmouth College Geisel School of Medicine. Hanover, NH, États-Unis.
- Program manager. (2017-2019). Génome Québec. Montreal, Quebec, Canada.
- Research Associate. (2016-2017). FoodChek Systems (Canada). Saint-Hyacinthe, Quebec, Canada.
Financement
-
Subvention.
Mechanisms of antimicrobial recalcitrance of Pseudomonas aeruginosa grown in a CF-relevant polymicrobial biofilm community.
Cystic Fibrosis Canada
(Toronto, Canada).
(2025-2028).
Numéro de subvention : 1349195. -
Subvention salariée.
Mechanisms of antimicrobial recalcitrance of clinically-relevant polymicrobial biofilms.
Fonds de Recherche du Québec - Santé
(QC, Canada).
(2025-2029).
Numéro de subvention : 376464. -
Subvention.
Infrastructure for mechanistic studies of antimicrobial recalcitrance in polymicrobial communities.
Canada Foundation for Innovation
(ON, Canada).
(2024-2025).
Numéro de subvention : 45207. -
Subvention.
Polymicrobial biofilms: Understanding community-specific phenotypes using molecular approaches.
NSERC
(Ottawa, Canada).
(2024-2029).
Numéro de subvention : RGPIN-2024-05211 . -
Subvention.
Polymicrobial communities in the cystic fibrosis lung: From in vitro modeling to airway infection treatment.
CRCHUS
(Sherbrooke, Canada).
(2024-2026).
Numéro de subvention : 00000 PAFI . -
Bourse.
Microbial interactions in the cystic fibrosis lung.
Cystic Fibrosis Foundation
(Md., États-Unis).
Postdoctoral.
129 050 USD.
(2021-2023).
Numéro de subvention : JEAN21F0.
Publications
Articles
- Bassam El Hafi, Fabrice Jean-Pierre, Lily Taub, Thomas H. Hampton, George A. O'Toole. (2026). Streptococcus sanguinis antagonizes Prevotella melaninogenica in the context of the cystic fibrosis respiratory microbiome. Journal of Bacteriology. DOI
- Bassam El Hafi, Fabrice Jean-Pierre, George A. O’Toole. (2025). Pseudomonas aeruginosa supports the survival of Prevotella melaninogenica in a cystic fibrosis lung polymicrobial community through metabolic cross-feeding. mBio. DOI
- Stacie Stuut Balsam, Amy Conaway, Dallas L. Mould, Fabrice Jean-Pierre, Deborah A. Hogan. (2025). Pseudomonas aeruginosa Dnr-regulated denitrification in microoxic conditions. Microbiology Spectrum. DOI
- Couture L, Jean-Pierre F, Côté JP. (2025). Building microbial communities to improve antimicrobial strategies. npj antimicrobials and resistance. DOI
- Rendi R. Rogers, Christopher A. Kesthely, Fabrice Jean-Pierre, Bassam El Hafi, George A. O'Toole. (2024). Dpr-mediated H 2 O 2 resistance contributes to streptococcus survival in a cystic fibrosis airway model system. Journal of Bacteriology. DOI
- Poirier S, Jean-Pierre F. (2024). Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes. Journal of visualized experiments : JoVE. DOI
- Fabrice Jean-Pierre, Thomas H Hampton, Daniel Schultz, Deborah A Hogan, Marie-Christine Groleau, Eric Déziel, George A O'Toole. (2023). Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system. eLife. DOI
- (2021). One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway. mBio. DOI
- (2021). Metabolic Modeling to Interrogate Microbial Disease: A Tale for Experimentalists. Frontiers in Molecular Biosciences. DOI
- (2020). Pseudomonas aeruginosa PA14 Enhances the Efficacy of Norfloxacin against Staphylococcus aureus Newman Biofilms. Journal of bacteriology. DOI
- (2017). Genomic characterisation of environmental Pseudomonas aeruginosa isolated from dental unit waterlines revealed the insertion sequence ISPa11 as a chaotropic element. FEMS microbiology ecology. DOI
- (2016). Broth versus Surface-Grown Cells: Differential Regulation of RsmY/Z Small RNAs in Pseudomonas aeruginosa by the Gac/HptB System. Frontiers in microbiology. DOI
- (2015). Complex autoregulation of the post-transcriptional regulator RsmA in Pseudomonas aeruginosa. Microbiology (Reading, England). DOI