Danielle Jacques

Prix et distinctions

• (2024) Certificat: Qualité d'enseignement remarquable. Université de Sherbrooke.
• (2017) Fellow. International Academy of Cardiovascular Sciences.
• (2016) Distinguished Service Award in Cardiovascular Science, Medicine and Surgery. International Academy of Cardiovascular Sciences.
• (2006) Prix -George Fodor Feature Symposium. CIHR Young Investigator Forum.
• (2004) Prize Alfred B. Grossman. Heart and Stroke Foundation.

Financement

• Subvention. Rôle d'un supplément de taurine pour la prévention de la nécrose, l'hypertrophie, de la défaillance cardiaque et de la mort prématurée dans la cardiomyopathie héréditaire. Canadian Institutes of Health Research (Ottawa, Canada). Project Grant program. 830 025 $. (2023-2028).
• Subvention. Modulation of cytosolic and nuclear calcium in endocardial endothelium by Endothelin-1. Natural Sciences and Engineering Research Council of Canada (Ottawa, Canada). Discovery Grant Program. 125 000 $. (2017-2023).
• Subvention. Modulation du tubule-T nucléaire dans l'hypertrophie et le vieillissement du muscle lisse vasculaire. Fonds de Recherche du Québec – Nature et Technologies (Québec, Canada). Projet de recherche en équipe. 177 000 $. (2013-2016).
• Subvention. Regulation of secretion of cardiac endocardial endothelial cells by neuropeptide Y. Heart and Stroke Foundation (Toronto, Canada). Grant-in-aid program. 141 693 $. (2013-2016).
• Subvention. Role of ET-1 and Ang II induced cytosolic and nuclear ROS generation in nuclear Ttubules formation in hypertrophy and ageing of human vascular smooth muscle cells. Canadian Institutes of Health Research (Ottawa, Canada). Project Grant program. 651 185 $. (2013-2020).
• Subvention. Role of sodium-hydrogen exchangers in the development of hereditary cardiomyopathy. Canadian Institutes of Health Research (Ottawa, Canada). Project Grant program. 663 327 $. (2012-2019).
• Subvention. Stress, platelet NPY and remodeling. National Institutes of Health (Bethesda, États-Unis). R01. 400 000 USD. (2008-2018).

Publications

Articles

• Ghassan Bkaily, Danielle Jacques, Ashley Jazzar. (2025). Exogenous and endogenous antioxidants (ROS) in Physiology and Pathology of the Cardiovascular System. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Ashley Jazzar, Amira Abou-Aichi, Danielle Jacques. (2025). Pathophysiology of Prediabetes Hyperinsulinemia and Insulin Resistance in the Cardiovascular System. Biomedicines. DOI
• Ashley Jazzar, Danielle Jacques, Amira Abou-Aichi, Ghassan Bkaily. (2025). In Vitro Chronic Hyperinsulinemia Induces Remodelling of Vascular Smooth Muscle Cells from Young Men and Women in a Sex Hormone Independent Manner. Pathophysiology. DOI
• Ghassan Bkaily, Yanick Simon, Joe Abou Abdallah, Chaimaa Ouertane, Amina Essalhi, Abdelouahed Khalil, Danielle Jacques. (2024). Short Communication: Taurine Long-Term Treatment Prevents the Development of Cardiac Hypertrophy, and Premature Death in Hereditary Cardiomyopathy of the Hamster Is Sex-Independent. Nutrients. DOI
• Danielle Jacques, Ghassan Bkaily. (2024). Taurine Prevents Angiotensin II-Induced Human Endocardial Endothelium Morphological Remodeling and the Increase in Cytosolic and Nuclear Calcium and ROS. Nutrients. DOI
• Yanick Simon, Danielle Jacques, Ghassan Bkaily. (2023). High salt-induced morphological and glycocalyx remodeling of human vascular smooth muscle cells is reversible but induces a high sodium salt-like sensitive memory. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Danielle Jacques. (2023). Calcium Homeostasis, Transporters, and Blockers in Health and Diseases of the Cardiovascular System. International Journal of Molecular Sciences. DOI
• Ghassan Bkaily, Danielle Jacques. (2023). Morphological and Functional Remodeling of Vascular Endothelium in Cardiovascular Diseases. International Journal of Molecular Sciences. DOI
• Ghassan Bkaily, Maram Ali Al-Shahrani, Moni Nader, Danielle Jacques. (2022). Age-dependent effect of insulin in the regulation of intracellular calcium in ventricular cardiomyocytes. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Yanick Simon, Alexandre Normand, Ashley Jazzar, Houssein Najibeddine, Abdelouahed Khalil, Danielle Jacques. (2022). Short-Communication: Short-Term Treatment with Taurine Prevents the Development of Cardiac Hypertrophy and Early Death in Hereditary Cardiomyopathy of the Hamster and Is Sex-Dependent. Nutrients. DOI
• Johny Al-Khoury, Danielle Jacques, Ghassan Bkaily. (2022). Hypotension in hereditary cardiomyopathy. Pflügers Archiv - European Journal of Physiology. DOI
• Ashley Jazzar, Danielle Jacques, Ghassan Bkaily. (2021). Insulin-Induced Cardiomyocytes Hypertrophy That Is Prevented by Taurine via β-alanine-Sensitive Na+-Taurine Symporter. Nutrients. DOI
• Ghassan Bkaily, Yanick Simon, Ashley Jazzar, Houssein Najibeddine, Alexandre Normand, Danielle Jacques. (2021). High Na+ Salt Diet and Remodeling of Vascular Smooth Muscle and Endothelial Cells. Biomedicines. DOI
• Ghassan Bkaily, Nadia Abou Abdallah, Yanick Simon, Ashley Jazzar, Danielle Jacques. (2021). Vascular smooth muscle remodeling in health and disease. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Danielle Jacques. (2020). Flaxseed as an Anticardiotoxicity Agent in Breast Cancer Therapy. The Journal of Nutrition. DOI
• Ghassan Bkaily, Ashley Jazzar, Alexandre Normand, Yanick Simon, Johny Al-Khoury, Danielle Jacques. (2020). Taurine and cardiac disease: state of the art and perspectives. Canadian Journal of Physiology and Pharmacology. DOI
• Marc Chamoun, Danielle Jacques, Ghassan Bkaily. (2019). Extracellular and intracellular tumor necrosis factor alpha modulates cytosolic and nuclear calcium in human cardiovascular cells. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Wassim Najibeddine, Danielle Jacques. (2019). Increase of NADPH oxidase 3 in heart failure of hereditary cardiomyopathy. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Chantale Provost, Alexandre Normand, Nadia Abou Abdallah, Johny Al-Khoury, Ghassan Bkaily. (2019). Angiotensin II induces apoptosis of human right and left ventricular endocardial endothelial cells by activating the AT2 receptor. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Ghassan Bkaily. (2019). Endocardial endothelial cell hypertrophy takes place during the development of hereditary cardiomyopathy. Molecular and Cellular Biochemistry. DOI
• Ghassan Bkaily, Yanick Simon, Istok Menkovic, Carl Bkaily, Danielle Jacques. (2018). High salt-induced hypertrophy of human vascular smooth muscle cells associated with a decrease in glycocalyx. Journal of Molecular and Cellular Cardiology. DOI
• Martin Houde, Adel Schwertani, Hanène Touil, Louisane Desbiens, Otman Sarrhini, Roger Lecomte, Martin Lepage, Hugo Gagnon, Shinji Takai, Gunnar Pejler, Danielle Jacques, Fernand Gobeil, Robert Day, Pedro D’Orléans-Juste. (2018). Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction. Frontiers in Pharmacology. DOI
• Ghada S. Hassan, Danielle Jacques, Pedro D’Orléans-Juste, Sheldon Magder, Ghassan Bkaily. (2018). Physical contact between human vascular endothelial and smooth muscle cells modulates cytosolic and nuclear calcium homeostasis. Canadian Journal of Physiology and Pharmacology. DOI
• Maud Kamal, Danielle Jacques, Ghassan Bkaily. (2017). Angiotensin II receptors’ modulation of calcium homeostasis in human vascular endothelial cells. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Nelly Abdel-Karim Abdel-Malak, Nadia Abou Abdallah, Johny Al-Khoury, Ghassan Bkaily. (2017). Difference in the response to angiotensin II between left and right ventricular endocardial endothelial cells. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Danielle Jacques. (2017). Na+–H+ exchanger and proton channel in heart failure associated with Becker and Duchenne muscular dystrophies. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Pedro D’Orléans-Juste, Sheldon Magder, Ghassan Bkaily. (2017). Neuropeptide Y and its receptors in ventricular endocardial endothelial cells. Canadian Journal of Physiology and Pharmacology. DOI
• Marianne Mikhail, Pierre H. Vachon, Pedro D’Orléans-Juste, Danielle Jacques, Ghassan Bkaily. (2017). Role of endothelin-1 and its receptors, ETA and ETB, in the survival of human vascular endothelial cells. Canadian Journal of Physiology and Pharmacology. DOI
• Dima Abdel-Samad, Ghassan Bkaily, Sheldon Magder, Danielle Jacques. (2016). ETA and ETB receptors contribute to neuropeptide Y-induced secretion of endothelin-1 in right but not left human ventricular endocardial endothelial cells. Neuropeptides. DOI
• Ghassan Bkaily, Mirna Chahine, Johny Al-Khoury, Levon Avedanian, Norbert Beier, Wolfgang Scholz, Danielle Jacques. (2015). Na+–H+ exchanger inhibitor prevents early death in hereditary cardiomyopathy. Canadian Journal of Physiology and Pharmacology. DOI
• Farah Jules, Levon Avedanian, Johny Al-Khoury, Ramatoulaye Keita, Alexandre Normand, Ghassan Bkaily, Danielle Jacques. (2015). Nuclear Membranes ETB Receptors Mediate ET-1–induced Increase of Nuclear Calcium in Human Left Ventricular Endocardial Endothelial Cells. Journal of Cardiovascular Pharmacology. DOI
• Ghassan Bkaily, Levon Avedanian, Johny Al-Khoury, Marc Chamoun, Rana Semaan, Cynthia Jubinville-Leblanc, Pedro D’Orléans-Juste, Danielle Jacques. (2015). Nuclear membrane R-type calcium channels mediate cytosolic ET-1-induced increase of nuclear calcium in human vascular smooth muscle cells. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Johny Al-Khoury, Danielle Jacques. (2014). Nuclear Membranes GPCRs: Implication in Cardiovascular Health and Diseases. Current Vascular Pharmacology. DOI
• Lena Ahmarani, Levon Avedanian, Johny Al-Khoury, Claudine Perreault, Danielle Jacques, Ghassan Bkaily. (2013). Whole-cell and nuclear NADPH oxidases levels and distribution in human endocardial endothelial, vascular smooth muscle, and vascular endothelial cells. Canadian Journal of Physiology and Pharmacology. DOI
• Dima Abdel-Samad, Claudine Perreault, Lena Ahmarani, Levon Avedanian, Ghassan Bkaily, Sheldon Magder, Pedro D’Orléans-Juste, Danielle Jacques. (2012). Differences in neuropeptide Y-induced secretion of endothelin-1 in left and right human endocardial endothelial cells. Neuropeptides. DOI
• Ghassan Bkaily, Levon Avedanian, Johny Al-Khoury, Lena Ahmarani, Claudine Perreault, Danielle Jacques. (2012). Receptors and ionic transporters in nuclear membranes: new targets for therapeutical pharmacological interventions. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Levon Avedanian, Johny Al-Khoury, Chantale Provost, Moni Nader, Pedro D'Orléans-Juste, Danielle Jacques. (2011). Nuclear membrane receptors for ET-1 in cardiovascular function. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. DOI
• Levon Avedanian, Danielle Jacques, Ghassan Bkaily. (2011). Presence of tubular and reticular structures in the nucleus of human vascular smooth muscle cells. Journal of Molecular and Cellular Cardiology. DOI
• Levon Avedanian, Julie Riopel, Ghassan Bkaily, Moni Nader, Pedro D’Orleans-Juste, Danielle Jacques. (2010). ETA receptors are present in human aortic vascular endothelial cells and modulate intracellular calcium This article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research. Canadian Journal of Physiology and Pharmacology. DOI
• Chantale Provost, Faten Choufani, Levon Avedanian, Ghassan Bkaily, Fernand Gobeil, Danielle Jacques. (2010). Nitric oxide and reactive oxygen species in the nucleus revisitedThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Levon Avedanian, Danielle Jacques. (2009). Nuclear membrane receptors and channels as targets for drug development in cardiovascular diseasesThis article is one of a selection of papers from the NATO Advanced Research Workshop on Translational Knowledge for Heart Health (published in part 1 of a 2-part Special Issue). Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Sanaa Choufani, Levon Avedanian, Lena Ahmarani, Moni Nader, Danielle Jacques, Pedro D’Orléans-Juste, Johny Al Khoury. (2008). Nonpeptidic antagonists of ETA and ETB receptors reverse the ET-1-induced sustained increase of cytosolic and nuclear calcium in human aortic vascular smooth muscle cells. This article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin. Canadian Journal of Physiology and Pharmacology. DOI
• Dima Abdel-Samad, Danielle Jacques, Claudine Perreault, Chantal Provost. (2007). NPY regulates human endocardial endothelial cell function. Peptides. DOI
• Danielle Jacques, Dima Abdel-Samad. (2007). Neuropeptide Y (NPY) and NPY receptors in the cardiovascular system: implication in the regulation of intracellular calcium. This paper is one of a selection of papers published in this Special Issue, entitled Young Investigators' Forum. Canadian Journal of Physiology and Pharmacology. DOI
• Johny Al-Khoury, Ghassan Bkaily, Mirna Chahine, Danielle Jacques, Pedro D'Orléans-Juste. (2006). ETB receptor dependent alteration in aortic responses to ET-1 in the cardiomyopathic hamster. This paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Sawsan Sader, Claudine Perreault, Dima Abdel-Samad, Chantale Provost. (2006). Roles of nuclear NPY and NPY receptors in the regulation of the endocardial endothelium and heart function. This paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Moni Nader, Levon Avedanian, Sana Choufani, Danielle Jacques, Pedro D’Orléans-Juste, Fernand Gobeil, Sylvain Chemtob, Johny Al-Khoury. (2006). G-protein-coupled receptors, channels, and Na+–H+ exchanger in nuclear membranes of heart, hepatic, vascular endothelial, and smooth muscle cells. This paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Sawsan Sader, Claudine Perreault, Dima Abdel-Samad, Farah Jules, Chantale Provost. (2006). NPY, ET-1, and Ang II nuclear receptors in human endocardial endothelial cells. This paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Nesrine El-Bizri, Moni Nader, Khaled M. Hazzouri, Julie Riopel, Danielle Jacques, Domenico Regoli, Pedro D’Orleans-Juste, Fernand Gobeil, Levon Avedanian. (2005). Angiotensin II induced increase in frequency of cytosolic and nuclear calcium waves of heart cells via activation of AT1 and AT2 receptors. Peptides. DOI
• Ghassan Bkaily, Adrian Sculptoreanu, Shimin Wang, Moni Nader, Khaled M. Hazzouri, Danielle Jacques, Domenico Regoli, Pedro D’Orleans-Juste, Levon Avedanian. (2005). Angiotensin II-induced increase of T-type Ca2+ current and decrease of L-type Ca2+ current in heart cells. Peptides. DOI
• Danielle Jacques, Magda Descorbeth, Dima Abdel-Samad, Chantale Provost, Claudine Perreault, Farah Jules. (2005). The distribution and density of ET-1 and its receptors are different in human right and left ventricular endocardial endothelial cells. Peptides. DOI
• M CHAHINE, G BKAILY, M NADER, J ALKHOURY, D JACQUES, N BEIER, W SCHOLZ. (2005). NHE-1-dependent intracellular sodium overload in hypertrophic hereditary cardiomyopathy: prevention by NHE-1 inhibitor. Journal of Molecular and Cellular Cardiology. DOI
• Ghassan Bkaily, Moni Nader, Levon Avedanian, Danielle Jacques, Claudine Perrault, Dima Abdel-Samad, Pedro D'Orléans-Juste, Fernand Gobeil, Khaled M Hazzouri. (2004). Immunofluorescence revealed the presence of NHE-1 in the nuclear membranes of rat cardiomyocytes and isolated nuclei of human, rabbit, and rat aortic and liver tissues. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Sanaa Choufani, Sawsan Sader, Danielle Jacques, Pedro d'Orléans-Juste, Moni Nader, Ghada Kurban, Maud Kamal. (2003). Activation of sarcolemma and nuclear membranes ET-1 receptors regulates transcellular calcium levels in heart and vascular smooth muscle cells. Canadian Journal of Physiology and Pharmacology. DOI
• G Bkaily, S Sleiman, J Stephan, C Asselin, S Choufani, M Kamal, D Jacques, F Gobeil, Jr, P D'Orléans-Juste. (2003). Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Nelly A. Abdel Malak, Sawsan Sader, Claudine Perreault. (2003). Angiotensin II and its receptors in human endocardial endothelial cells: role in modulating intracellular calcium. Canadian Journal of Physiology and Pharmacology. DOI
• Nesrine El-Bizri, Ghassan Bkaily, Shimin Wang, Danielle Jacques, Domenico Regoli, Pedro D'Orléans-Juste, Rami Sukarieh. (2003). Bradykinin induced a positive chronotropic effect via stimulation of T- and L-type calcium currents in heart cells. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan Bkaily, Nesrine El-Bizri, Michel Bui, Rami Sukarieh, Danielle Jacques, Michael L.X Fu. (2003). Modulation of intracellular Ca2+ via L-type calcium channels in heart cells by the autoantibody directed against the second extracellular loop of the α1-adrenoceptors. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Sawsan Sader, Claudine Perreault, Alain Fournier, Georges Pelletier, Annette G Beck-Sickinger, Magda Descorbeth. (2003). Presence of neuropeptide Y and the Y1 receptor in the plasma membrane and nuclear envelope of human endocardial endothelial cells: modulation of intracellular calcium. Canadian Journal of Physiology and Pharmacology. DOI
• Danielle Jacques, Ghassan Bkaily, Gaétan Jasmin, Pedro D'Orléans-Juste, Mirna Chahine. (2003). Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster. Canadian Journal of Physiology and Pharmacology. DOI
• Ghassan BKAILY, Danie MASSAAD, Sanaa CHOUFANI, Danielle JACQUES, Pedro D'ORLÉANS-JUSTE. (2002). Role of endothelin-1 receptors in the sarcolemma membrane and the nuclear membrane in the modulation of basal cytosolic and nuclear calcium levels in heart cells. Clinical Science. DOI
• Dumont Y, Cadieux A, Doods H, Pheng LH, Abounader R, Hamel E, Jacques D, Regoli D, Quirion R. (2000). BIIE0246, a potent and highly selective non-peptide neuropeptide Y Y(2) receptor antagonist. British journal of pharmacology. DOI
• Jacques D, Sader S, El-Bizri N, Chouffani S, Hassan G, Shbaklo H. (2000). Neuropeptide Y induced increase of cytosolic and nuclear Ca2+ in heart and vascular smooth muscle cells. Canadian journal of physiology and pharmacology. DOI
• Danielle Jacques, Sawsan Sader, Sanaa Choufani, Pedro DʼOrleéans-Juste, Dany Charest. (2000). Endothelin-1 Regulates Cytosolic and Nuclear Ca2+ in Human Endocardial Endothelium. Journal of Cardiovascular Pharmacology. DOI
• Ghassan Bkaily, Hadia Shbaklo, Magda Taoudi-Benchekroun, Sawsan Sader, Martine Duval, Danielle Jacques, Pedro DʼOrléans-Juste. (2000). Nitric Oxide Relaxes the Vascular Smooth Muscle Independently of Endothelin-1- and U46619-Induced Intracellular Increase of Calcium. Journal of Cardiovascular Pharmacology. DOI
• Ghassan Bkaily, Sanaa Choufani, Ghada Hassan, Nesrine El-Bizri, Danielle Jacques, Pedro DʼOrléans-Juste. (2000). Presence of Functional Endothelin-1 Receptors in Nuclear Membranes of Human Aortic Vascular Smooth Muscle Cells. Journal of Cardiovascular Pharmacology. DOI
• Dumont Y, Jacques D, Bouchard P, Quirion R. (1998). Species differences in the expression and distribution of the neuropeptide Y Y1, Y2, Y4, and Y5 receptors in rodents, guinea pig, and primates brains. The Journal of comparative neurology. DOI
• Bkaily G, Jaalouk D, Sader S, Shbaklo H, Pothier P, Jacques D, D'Orléans-Juste P, Cragoe EJ Jr, Bose R. (1998). Taurine indirectly increases [Ca]i by inducing Ca2+ influx through the Na(+)-Ca2+ exchanger. Molecular and cellular biochemistry. DOI
• Jacques D, Tong Y, Shen SH, Quirion R. (1998). Discrete distribution of the neuropeptide Y Y5 receptor gene in the human brain: an in situ hybridization study. Brain research. Molecular brain research. DOI
• Ghassan Bkaily, Radha Naik, Doris Jaalouk, Danielle Jacques, Demetri Economos, Pédro D'Orléans-Juste, Pierre Pothier. (1998). Endothelin-1 and insulin activate the steady-state voltage dependent R-type Ca2+ channel in aortic smooth muscle cells via a pertussis toxin and cholera toxin sensitive G-protein. Molecular and Cellular Biochemistry. DOI
• Jacques D, Bkaily G, Jasmin G, Ménard D, Proschek L. (1997). Early fetal like slow Na+ current in heart cells of cardiomyopathic hamster. Molecular and cellular biochemistry. DOI
• Bkaily G, Sculptoreanu A, Jacques D, Jasmin G. (1997). Increases of T-type Ca2+ current in heart cells of the cardiomyopathic hamster. Molecular and cellular biochemistry. DOI
• Jacques D, Dumont Y, Fournier A, Quirion R. (1997). Characterization of neuropeptide Y receptor subtypes in the normal human brain, including the hypothalamus. Neuroscience. DOI
• Bkaily G, Pothier P, D'Orléans-Juste P, Simaan M, Jacques D, Jaalouk D, Belzile F, Hassan G, Boutin C, Haddad G, Neugebauer W. (1997). The use of confocal microscopy in the investigation of cell structure and function in the heart, vascular endothelium and smooth muscle cells. Molecular and cellular biochemistry. DOI
• Jacques D, Tong Y, Dumont Y, Shen SH, Quirion R. (1996). Expression of the neuropeptide Y Y1 receptor mRNA in the human brain: an in situ hybridization study. Neuroreport. DOI
• Krieger C, Jacques D, Parent A, Quirion R. (1995). [3H]phorbol 12,13-dibutyrate/PKC binding in thoracic spinal cord: no change in amyotrophic lateral sclerosis. Neuroreport. DOI
• Jacques D, Cadieux A, Dumont Y, Quirion R. (1995). Apparent affinity and potency of BIBP3226, a non-peptide neuropeptide Y receptor antagonist, on purported neuropeptide Y Y1, Y2 and Y3 receptors. European journal of pharmacology. DOI
• Bkaily G, Perron N, Wang S, Sculptoreanu A, Jacques D, Ménard D. (1993). Atrial natriuretic factor blocks the high-threshold Ca2+ current and increases K+ current in fetal single ventricular cells. Journal of molecular and cellular cardiology. DOI
• Bkaily G, Sculptoreanu A, Jacques D, Economos D, Ménard D. (1992). Apamin, a highly potent fetal L-type Ca2+ current blocker in single heart cells. The American journal of physiology. DOI
• Bkaily G, Jacques D, Sculptoreanu A, Yamamoto T, Carrier D, Vigneault D, Sperelakis N. (1991). Apamin, a highly potent blocker of the TTX- and Mn2(+)-insensitive fast transient Na+ current in young embryonic heart. Journal of molecular and cellular cardiology. DOI
• Bkaily G, Jasmin G, Tautu C, Prochek L, Yamamoto T, Sculptoreanu A, Peyrow M, Jacques D. (1990). A tetrodotoxin- and Mn2(+)-insensitive Na+ current in Duchenne muscular dystrophy. Muscle & nerve. DOI
• Bkaily G, Peyrow M, Sculptoreanu A, Jacques D, Chahine M, Regoli D, Sperelakis N. (1988). Angiotensin II increases Isi and blocks IK in single aortic cell of rabbit. Pflugers Archiv : European journal of physiology. DOI
• Bkaily G, Jacques D, Yamamoto T, Sculptoreanu A, Payet MD, Sperelakis N. (1988). Three types of slow inward currents as distinguished by melittin in 3-day-old embryonic heart. Canadian journal of physiology and pharmacology. DOI
• Bkaily G, Peyrow M, Yamamoto T, Sculptoreanu A, Jacques D, Sperelakis N. (1988). Macroscopic Ca2+ -Na+ and K+ currents in single heart and aortic cells. Molecular and cellular biochemistry. DOI

Chapitres de livre

• Ghassan Bkaily, Johny Al-Khoury, Yanick Simon, Danielle Jacques. (2017). Intracellular Free Calcium Measurement Using Confocal Imaging. Methods in Molecular Biology. DOI
• Ghassan Bkaily, Danielle Jacques, Pierre Pothier. (1999). Use of confocal microscopy to investigate cell structure and function. Methods in Enzymology. DOI
• Danielle Jacques, Sawsan Sader, Claudine Perreault, Dima Abdel-Samad. NPY and NPY receptors: presence, distribution and roles in the regulation of the endocardial endothelium and cardiac function. Experientia Supplementum. DOI

Autres contributions

Cours enseignés à l'UdeS

• BCL106 - Cytophysiologie. (2023-2025). (2CR).
• BCL709 - Bioélectricité membranaire du muscle lisse. (2023-2025). (2CR).

Activités professionnelles

• Nutrients. Associate editor. (2022-).
• Annual meeting of the International Academy of Cardiovascular Sciences- North American Section. Secretary of the local organizing committee. Sherbrooke, Quebec, Canada. (2016-).
• Canadian Journal of Physiology and Pharmacology. Associate editor. (2016-2022).
• International Society for Heart Research. Secretary of the organizing committee of the satellite meeting in Montreal, Qc, Canada. Durham, North Carolina, États-Unis. (2001).