Nathalie Rivard

Prix et distinctions

• (2016) RECMUS Prize (an award that recognizes the excellence of graduate student training). Université de Sherbrooke.
• (2015) Etienne-LeBel award (an award that recognizes research excellence). Université de Sherbrooke.
• (2014) Fellow. American Gastroenterological Association.
• (2013) Research Excellence Award. Canadian Association of Gastroenterology.
• (2006) Pierre-et-Danielle-Bourgaux Prize. Université de Sherbrooke.
• (2006) Young Investigator Award. Canadian Association of Gastroenterology.

Financement

• Subvention. Understanding the interplay between Shp-2 and microbiota in colonic inflammation. CIHR (Ottawa, Canada). 994 500 $. (2023-2028).
• Subvention. Exploring the role of Shp-2 in APC-mutated colorectal cancer. Cancer Research Society (Montreal, Canada). 120 000 $. (2021-2023).
• Subvention. Understanding the interplay between Shp-2 and microbiota in colonic inflammation. CIHR (Ottawa, Canada). 100 000 $. (2021-2022).
• Subvention. A critical role for DUal Specificity Phosphatase 4 in intestinal oncogenesis?. CIHR (Ottawa, Canada). 803 250 $. (2019-2024).
• Subvention salariée. Canada Research Chair in colorectal cancer and inflammatory cell signaling. CIHR (Ottawa, Canada). 1 400 000 $. (2018-2025).

Publications

Articles

• Martineau CA, Rivard N, Bisaillon M. (2024). From viruses to cancer: exploring the role of the hepatitis C virus NS3 protein in carcinogenesis. Infectious agents and cancer. DOI
• Lannoy V, Côté-Biron A, Asselin C, Rivard N. (2023). TIRAP, TRAM, and Toll-Like Receptors: The Untold Story. Mediators of inflammation. DOI
• Valdes J, Gagné-Sansfaçon J, Reyes V, Armas A, Marrero G, Moyo-Muamba M, Ramanathan S, Perreault N, Ilangumaran S, Rivard N, Fortier LC, Menendez A. (2022). Defects in the expression of colonic host defense factors associate with barrier dysfunction induced by a high-fat/high-cholesterol diet. Anatomical record (Hoboken, N.J. : 2007). DOI
• St-Jean S, De Castro AC, Lecours M, Jones C, Rivard N, Rodier F, Perreault N, Boudreau F. (2021). NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence. Cancers. DOI
• Raisch J, Côté-Biron A, Langlois MJ, Leblanc C, Rivard N. (2021). Unveiling the Roles of Low-Density Lipoprotein Receptor-Related Protein 6 in Intestinal Homeostasis, Regeneration and Oncogenesis. Cells. DOI
• Lannoy V, Côté-Biron A, Asselin C, Rivard N. (2021). Phosphatases in toll-like receptors signaling: the unfairly-forgotten. Cell communication and signaling : CCS. DOI
• Girondel C, Lévesque K, Langlois MJ, Pasquin S, Saba-El-Leil MK, Rivard N, Friesel R, Servant MJ, Gauchat JF, Lesage S, Meloche S. (2020). Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis. Oncogene. DOI
• Jodoin R, Carrier JC, Rivard N, Bisaillon M, Perreault JP. (2019). G-quadruplex located in the 5'UTR of the BAG-1 mRNA affects both its cap-dependent and cap-independent translation through global secondary structure maintenance. Nucleic acids research. DOI
• Raisch J, Côté-Biron A, Rivard N. (2019). A Role for the WNT Co-Receptor LRP6 in Pathogenesis and Therapy of Epithelial Cancers. Cancers. DOI
• Lauzier A, Normandeau-Guimond J, Vaillancourt-Lavigueur V, Boivin V, Charbonneau M, Rivard N, Scott MS, Dubois CM, Jean S. (2019). Colorectal cancer cells respond differentially to autophagy inhibition in vivo. Scientific reports. DOI
• Langlois MJ, Servant R, Reyes Nicolás V, Jones C, Roy SAB, Paquet M, Carrier JC, Rivard N, Boudreau F, Perreault N. (2019). Loss of PTEN Signaling in Foxl1⁺ Mesenchymal Telocytes Initiates Spontaneous Colonic Neoplasia in Mice. Cellular and molecular gastroenterology and hepatology. DOI
• Gagné-Sansfacon J, Langlois A, Langlois MJ, Coulombe G, Tremblay S, Vaillancourt-Lavigueur V, Qu CK, Menendez A, Rivard N. (2018). The tyrosine phosphatase Shp-2 confers resistance to colonic inflammation by driving goblet cell function and crypt regeneration. The Journal of pathology. DOI
• Beaudry K, Langlois MJ, Montagne A, Cagnol S, Carrier JC, Rivard N. (2018). Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis. Journal of cellular physiology. DOI
• Leblanc C, Langlois MJ, Coulombe G, Vaillancourt-Lavigueur V, Jones C, Carrier JC, Boudreau F, Rivard N. (2017). Epithelial Src homology region 2 domain-containing phosphatase-1 restrains intestinal growth, secretory cell differentiation, and tumorigenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. DOI
• Gagné-Sansfaçon J, Coulombe G, Langlois MJ, Langlois A, Paquet M, Carrier J, Feng GS, Qu CK, Rivard N. (2016). SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development. Oncotarget. DOI
• Coulombe G, Langlois A, De Palma G, Langlois MJ, McCarville JL, Gagné-Sanfaçon J, Perreault N, Feng GS, Bercik P, Boudreau F, Verdu EF, Rivard N. (2016). SHP-2 Phosphatase Prevents Colonic Inflammation by Controlling Secretory Cell Differentiation and Maintaining Host-Microbiota Homeostasis. Journal of cellular physiology. DOI
• Gonneaud A, Turgeon N, Boudreau F, Perreault N, Rivard N, Asselin C. (2016). Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis. Journal of cellular physiology. DOI
• Coulombe G, Rivard N. (2015). New and Unexpected Biological Functions for the Src-Homology 2 Domain-Containing Phosphatase SHP-2 in the Gastrointestinal Tract. Cellular and molecular gastroenterology and hepatology. DOI
• Bian B, Mongrain S, Cagnol S, Langlois MJ, Boulanger J, Bernatchez G, Carrier JC, Boudreau F, Rivard N. (2015). Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis. Molecular carcinogenesis. DOI
• Lemieux E, Cagnol S, Beaudry K, Carrier J, Rivard N. (2014). Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer. Oncogene. DOI

Autres contributions

Activités professionnelles

• Cancers. Member of Editorial Board. (2021-).