Jean-Pierre Perreault

Prix et distinctions

• Honour for quality of training and supervision of graduate students. Université de Sherbrooke.
• (2021) Mérite Estrien. Plusieurs organisations des Cantons-de-l'Est.
• (2017) Researcher of the month of June. Centre de recherche du Centre hospitalier universitaire de Sherbrooke.
• (2006) Team of the year 2006. Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke.
• (1995) Young Investigator Participation. North Carolina State University.
• (1991) Prix d'Excellence. Académie des Grands Montréalais.

Financement

• Subvention. CRSH - Subvention institutionnelle. CRSH (Ottawa, Canada). Institutional grant. 180 000 $. (2022-2025).
• Subvention. Transcriptomique comparative des G-quadruplexes d’ARN à travers diverses espèces. Fonds de Recherche du Québec – Nature et Technologies (Québec, Canada). Subvention d'équipe. 162 000 $. (2018-2021).
• Subvention. CRSH - Subvention institutionnelle. Conseil de Recherches en Sciences Humaines (Ottawa, Canada). Institutional grant. 198 000 $. (2018-2022).
• Subvention. RNA Bioengineering and Innovation Network. CRSNG (Ottawa, Canada). Program CREATE. 1 650 000 $. (2018-2025).
• Subvention. Biochemistry and molecular biology of a model viroid. CRSNG (Ottawa, Canada). Discovery grant. 300 000 $. (2017-2023).
• Subvention. Molecular study of the interaction between plants and viroids. Fonds de Recherche du Québec – Nature et Technologies (Québec, Canada). Team grant. 162 000 $. (2017-2020).
• Subvention. Nouveaux biomarqueurs pour la détection précoce du cancer oropharyngé. Université de Sherbrooke - Département de chirurgie (Sherbrooke, Canada). FMSS - Merck Sharpe & Dohme. 50 000 $. (2017-2018).
• Subvention. Nouveaux biomarqueurs urinaires pour la détection de récidive tumorale : les évènements d’épissage alternatif comme nouvel outil diagnostic chez les patients atteints du cancer de la vessie. Université de Sherbrooke - Dept de chirurgie (Sherbrooke, Canada). Initiative de recherche. 50 000 $. (2017-2018).
• Subvention. Structural study of G-quadruplexes. Fonds de Recherche du Québec – Nature et Technologies (Québec, Canada). Team program. 144 000 $. (2015-2018).
• Subvention. Modification des évènements d’épissage alternative dans les cancers induits par les virus : un nouveau paradigme pour la recherche translationnelle et la médecine personnalisée. Université de Sherbrooke (Sherbrooke, Canada). FMSS - Merck Sharpe & Dohme. 50 000 $. (2015-2016).

Publications

Articles

• Turcotte, M.-A., Perreault, J.-P. (2025). RNA G-Quadruplex Reprogramming with Guanine-Rich Antisense Oligonucleotides Inhibits Monoamine Oxidase B’s Translation. ACS Bio and Med Chem Au. DOI
• Naoi, T., Zhang, Z., Adkar-Purushothama, C.R., Perreault, J.-P., Sano, T. (2025). Resistance and tolerance to viroid infection: status and prospects. Journal of General Plant Pathology. DOI
• Turcotte, M.-A., Perreault, J.-P. (2024). Pathogenic SNPs Affect Both RNA and DNA G-Quadruplexes’ Responses to Ligands. ACS Chemical Biology. DOI
• Adkar-Purushothama, C.R., Lejault, P., Turcotte, M.-A., Perreault, J.-P. (2024). Viroids: infectious non coding RNAs,Les viroïdes: des ARN infectieux non codants. Virologie. DOI
• Turcotte, M.-A., Bolduc, F., Vannutelli, A., Mitteaux, J., Monchaud, D., Perreault, J.-P. (2023). Development of a highly optimized procedure for the discovery of RNA G-quadruplexes by combining several strategies. Biochimie. DOI
• Vannutelli, A., Schell, L.L.N., Perreault, J.-P., Ouangraoua, A. (2023). GAIA: G-quadruplexes in alive creature database. Nucleic Acids Research. DOI
• Adkar-Purushothama, C.R., Sano, T., Perreault, J.-P. (2023). Hop Latent Viroid: A Hidden Threat to the Cannabis Industry. Viruses. DOI
• Lejault, P., Prudent, L., Terrier, M.-P., Perreault, J.-P. (2023). Small molecule chaperones facilitate the folding of RNA G-quadruplexes. Biochimie. DOI
• Vannutelli, A., Ouangraoua, A., Perreault, J.-P. (2023). Toward a Better Understanding of G4 Evolution in the 3 Living Kingdoms. Evolutionary Bioinformatics. DOI
• Jodoin, R., Carrier, J.C., Rivard, N., Bisaillon, M., Perreault, J.-P. (2022). G-quadruplex located in the 5UTR of the BAG-1 mRNA affects both its cap-dependent and cap-independent translation through global secondary structure maintenance. Nucleic Acids Research. DOI
• Vannutelli, A., Perreault, J.-P., Ouangraoua, A. (2022). G-quadruplex occurrence and conservation: More than just a question of guanine-cytosine content. Nar Genomics and Bioinformatics. DOI
• Boudreault, S., Durand, M., Martineau, C.-A., Perreault, J.-P., Lemay, G., Bisaillon, M. (2022). Reovirus μ2 protein modulates host cell alternative splicing by reducing protein levels of U5 snRNP core components. Nucleic Acids Research. DOI
• Katsarou, K., Adkar-Purushothama, C.R., Tassios, E., Samiotaki, M., Andronis, C., Lisón, P., Nikolaou, C., Perreault, J.-P., Kalantidis, K. (2022). Revisiting the Non-Coding Nature of Pospiviroids. Cells. DOI
• Xu, D., Adkar-Purushothama, C.R., Lemoyne, P., Perreault, J.-P., Fall, M.L. (2021). First Report of Grapevine Yellow Speckle Viroid 1 Infecting Grapevine (Vitis vinifera) in Canada. Plant Disease. DOI
• Turcotte, M.-A., Garant, J.-M., Cossette-Roberge, H., Perreault, J.-P. (2021). Guanine Nucleotide-Binding Protein-Like 1 (GNL1) binds RNA G-quadruplex structures in genes associated with Parkinson’s disease. RNA Biology. DOI
• Adkar‐purushothama, C.R., Iyer, P.S., Sano, T., Perreault, J.-P. (2021). Srna profiler: A user‐focused interface for small rna mapping and profiling. Cells. DOI
• Adkar-Purushothama, C.R., Perreault, J.-P. (2020). Current overview on viroid–host interactions. Wiley Interdisciplinary Reviews RNA. DOI
• Adkar-Purushothama, C.R., Perreault, J.-P. (2020). Impact of nucleic acid sequencing on viroid biology. International Journal of Molecular Sciences. DOI
• Adkar-Purushothama, C.R., Bolduc, F., Bru, P., Perreault, J.-P. (2020). Insights Into Potato Spindle Tuber Viroid Quasi-Species From Infection to Disease. Frontiers in Microbiology. DOI
• Bolduc, F., Turcotte, M.-A., Perreault, J.-P. (2020). The Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA) binds to the G-quadruplex of the BAG-1 5′UTR. Biochimie. DOI
• Vannutelli, A., Belhamiti, S., Garant, J.-M., Ouangraoua, A., Perreault, J.-P. (2020). Where are G-quadruplexes located in the human transcriptome?. Nar Genomics and Bioinformatics. DOI
• Cottilli, P., Belda-Palazón, B., Adkar-Purushothama, C.R., Perreault, J.-P., Schleiff, E., Rodrigo, I., Ferrando, A., Lisón, P. (2019). Citrus exocortis viroid causes ribosomal stress in tomato plants. Nucleic Acids Research. DOI
• Brodeur, C.M., Thibault, P., Durand, M., Perreault, J.-P., Bisaillon, M. (2019). Dissecting the expression landscape of cytochromes P450 in hepatocellular carcinoma: Towards novel molecular biomarkers. Genes and Cancer. DOI
• Adkar-Purushothama, C.R., Perreault, J.-P. (2019). Suppression of RNA-dependent RNA polymerase 6 favors the accumulation of potato spindle tuber viroid in nicotiana benthamiana. Viruses. DOI
• Boudreault, S., Armero, V.E.S., Scott, M.S., Perreault, J.-P., Bisaillon, M. (2019). The Epstein-Barr virus EBNA1 protein modulates the alternative splicing of cellular genes. Virology Journal. DOI
• Adkar-Purushothama, C.R., Perreault, J.-P. (2018). Alterations of the viroid regions that interact with the host defense genes attenuate viroid infection in host plant. RNA Biology. DOI
• Rouleau, S.G., Garant, J.-M., Bolduc, F., Bisaillon, M., Perreault, J.-P. (2018). G-Quadruplexes influence pri-microRNA processing. RNA Biology. DOI
• Jodoin, R., Perreault, J.-P. (2018). G-quadruplexes formation in the 5’UTRs of mRNAs associated with colorectal cancer pathways. Plos One. DOI
• Garant, J.-M., Perreault, J.-P., Scott, M.S. (2018). G4RNA screener web server: User focused interface for RNA G-quadruplex prediction. Biochimie. DOI
• Adkar-Purushothama, C.R., Sano, T., Perreault, J.-P. (2018). Viroid-derived small RNA induces early flowering in tomato plants by RNA silencing. Molecular Plant Pathology. DOI
• Adkar-Purushothama, C.R., Bru, P., Perreault, J.-P. (2017). 3′ RNA ligase mediated rapid amplification of cDNA ends for validating viroid induced cleavage at the 3′ extremity of the host mRNA. Journal of Virological Methods. DOI
• Rouleau, S., Glouzon, J.-P.S., Brumwell, A., Bisaillon, M., Perreault, J.-P. (2017). 3′ UTR G-quadruplexes regulate miRNA binding. RNA. DOI
• Giguère, T., Perreault, J.-P. (2017). Classification of the Pospiviroidae based on their structural hallmarks. Plos One. DOI
• Garant, J.-M., Perreault, J.-P., Scott, M.S. (2017). Motif independent identification of potential RNA G-quadruplexes by G4RNA screener. Bioinformatics. DOI
• Adkar-Purushothama, C.R., Iyer, P.S., Perreault, J.-P. (2017). Potato spindle tuber viroid infection triggers degradation of chloride channel protein CLC-b-like and Ribosomal protein S3a-like mRNAs in tomato plants. Scientific Reports. DOI
• Glouzon, J.-P.S., Perreault, J.-P., Wang, S. (2017). Structurexplor: A platform for the exploration of structural features of RNA secondary structures. Bioinformatics. DOI
• Glouzon, J.-P.S., Perreault, J.-P., Wang, S. (2017). The super-n-motifs model: A novel alignment-free approach for representing and comparing RNA secondary structures. Bioinformatics. DOI
• Armero, V.E.S., Tremblay, M.-P., Allaire, A., Boudreault, S., Martenon-Brodeur, C., Duval, C., Durand, M., Lapointe, E., Thibault, P., Tremblay-Létourneau, M., Perreault, J.-P., Scott, M.S., Bisaillon, M. (2017). Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virusassociated gastric carcinomas. Plos One. DOI
• Tremblay, M.-P., Armero, V.E.S., Allaire, A., Boudreault, S., Martenon-Brodeur, C., Durand, M., Lapointe, E., Thibault, P., Tremblay-Létourneau, M., Perreault, J.-P., Scott, M.S., Bisaillon, M. (2016). Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma. BMC Genomics. DOI
• Boudreault, S., Martenon-Brodeur, C., Caron, M., Garant, J.-M., Tremblay, M.-P., Armero, V.E.S., Durand, M., Lapointe, E., Thibault, P., Tremblay-Létourneau, M., Perreault, J.-P., Scott, M.S., Lemay, G., Bisaillon, M. (2016). Global profiling of the cellular alternative RNA splicing landscape during virus-host interactions. Plos One. DOI
• Bolduc, F., Garant, J.-M., Allard, F., Perreault, J.-P. (2016). Irregular G-quadruplexes found in the untranslated regions of human mRNAs influence translation. Journal of Biological Chemistry. DOI
• Adkar-Purushothama, C.R., Perreault, J.-P., Sano, T. (2015). Analysis of small RNA production patterns among the two potato spindle tuber viroid variants in tomato plants. Genomics Data. DOI
• Thandapani, P., Song, J., Gandin, V., Cai, Y., Rouleau, S.G., Garant, J.-M., Boisvert, F.-M., Yu, Z., Perreault, J.-P., Topisirovic, I., Richard, S. (2015). Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes. Elife. DOI
• Garant, J.-M., Luce, M.J., Scott, M.S., Perreault, J.-P. (2015). G4RNA: An RNA G-quadruplex database. Database. DOI
• Adkar-Purushothama, C.R., Brosseau, C., Gigu È Re, T., Sano, T., Moffett, P., Perreaulta, J.-P. (2015). Small RNA derived from the virulence modulating region of the potato spindle tuber viroid silences callose synthase genes of tomato plants. Plant Cell. DOI
• Rouleau, S.G., Beaudoin, J.-D., Bisaillon, M., Perreault, J.-P. (2015). Small antisense oligonucleotides against G-quadruplexes: Specific mRNA translational switches. Nucleic Acids Research. DOI
• Scarborough, R.J., Lévesque, M.V., Boudrias-Dalle, E., Chute, I.C., Daniels, S.M., Ouellette, R.J., Perreault, J.-P., Gatignol, A. (2014). A conserved target site in HIV-1 gag RNA is accessible to inhibition by both an HDV Ribozyme and a Short Hairpin RNA. Molecular Therapy Nucleic Acids. DOI
• Giguère, T., Adkar-Purushothama, C.R., Perreault, J.-P. (2014). Comprehensive secondary structure elucidation of four genera of the family Pospiviroidae. Plos One. DOI
• Glouzon, J.-P.S., Bolduc, F., Wang, S., Najmanovich, R.J., Perreault, J.-P. (2014). Correction: Deep-sequencing of the peach latent mosaic viroid reveals new aspects of population heterogeneity (PLoS ONE (2014) 9, 1 (e87297) DOI:10.1371/journal.pone.0087297). Plos One. DOI
• Glouzon, J.-P.S., Bolduc, F., Wang, S., Najmanovich, R.J., Perreault, J.-P. (2014). Deep-sequencing of the peach latent mosaic viroid reveals new aspects of population heterogeneity. Plos One. DOI
• Giguère, T., Adkar-Purushothama, C.R., Bolduc, F., Perreault, J.-P. (2014). Elucidation of the structures of all members of the Avsunviroidae family. Molecular Plant Pathology. DOI
• Beaudoin, J.-D., Jodoin, R., Perreault, J.-P. (2014). New scoring system to identify RNA G-quadruplex folding. Nucleic Acids Research. DOI
• Brosseau, J.-P., Lucier, J.-F., Lamarche, A.-A., Shkreta, L., Gendron, D., Lapointe, E., Thibault, P., Paquet, E., Perreault, J.-P., Elela, S.A., Chabot, B. (2014). Redirecting splicing with bifunctional oligonucleotides. Nucleic Acids Research. DOI
• Jodoin, R., Bauer, L., Garant, J.-M., Laaref, A.M., Phaneuf, F., Perreault, J.-P. (2014). The folding of 5′-UTR human G-quadruplexes possessing a long central loop. RNA. DOI
• Brosseau, J.-P., Lucier, J.-F., Nwilati, H., Thibault, P., Garneau, D., Gendron, D., Durand, M., Couture, S., Lapointe, E., Prinos, P., Klinck, R., Perreault, J.-P., Chabot, B., Abou-Elela, S. (2014). Tumor microenvironment-associated modifications of alternative splicing. RNA. DOI
• Beaudoin, J.-D., Perreault, J.-P. (2013). Exploring mRNA 3′-UTR G-quadruplexes: Evidence of roles in both alternative polyadenylation and mRNA shortening. Nucleic Acids Research. DOI
• Beaudoin, J.-D., Jodoin, R., Perreault, J.-P. (2013). In-line probing of RNA G-quadruplexes. Methods. DOI
• Lévesque, D., Reymond, C., Perreault, J.-P. (2012). Characterization of the trans Watson-Crick GU base pair located in the catalytic core of the antigenomic HDV ribozyme. Plos One. DOI
• Rouleau, S.G., Jodoin, R., Bisaillon, M., Perreault, J.-P. (2012). Programming a highly structured ribozyme into complex allostery using RNA oligonucleotides. ACS Chemical Biology. DOI
• Ben Aissa, M., April, M.-C., Bergeron, L.-J., Perreault, J.-P., Levesque, G. (2012). Silencing of amyloid precursor protein expression using a new engineered delta ribozyme. International Journal of Alzheimer S Disease. DOI
• Xu, W., Bolduc, F., Hong, N., Perreault, J.-P. (2012). The use of a combination of computer-assisted structure prediction and SHAPE probing to elucidate the secondary structures of five viroids. Molecular Plant Pathology. DOI
• Motard, J., Rouxel, R., Paun, A., von Messling, V., Bisaillon, M., Perreault, J.-P. (2011). A novel Ribozyme-Based prophylaxis inhibits influenza a virus replication and protects from severe disease. Plos One. DOI
• Prinos, P., Garneau, D., Lucier, J.-F., Gendron, D., Couture, S., Boivin, M., Brosseau, J.-P., Lapointe, E., Thibault, P., Durand, M., Tremblay, K., Gervais-Bird, J., Nwilati, H., Klinck, R., Chabot, B., Perreault, J.-P., Wellinger, R.J., Elela, S.A. (2011). Alternative splicing of SYK regulates mitosis and cell survival. Nature Structural and Molecular Biology. DOI
• Lainé, S., Scarborough, R.J., Lévesque, D., Didierlaurent, L., Soye, K.J., Mougel, M., Perreault, J.-P., Gatignol, A. (2011). In vitro and in vivo cleavage of HIV-1 RNA by new SOFA-HDV ribozymes and their potential to inhibit viral replication. RNA Biology. DOI
• Dubé, A., Bolduc, F., Bisaillon, M., Perreault, J.-P. (2011). Mapping studies of the Peach latent mosaic viroid reveal novel structural features. Molecular Plant Pathology. DOI
• D'Anjou, F., Routhier, S., Perreault, J.-P., Latil, A., Bonnel, D., Fournier, I., Salzet, M., Day, R. (2011). Molecular validation of pace4 as a target in prostate cancer. Translational Oncology. DOI
• Lévesque, M.V., Rouleau, S.G., Perreault, J.-P. (2011). Selection of the most potent specific on/off adaptor-hepatitis delta virus ribozymes for use in gene targeting. Nucleic Acid Therapeutics. DOI
• Beaudoin, J.-D., Perreault, J.-P. (2010). 5′-UTR G-quadruplex structures acting as translational repressors. Nucleic Acids Research. DOI
• Reymond, C., Lévesque, D., Bisaillon, M., Perreault, J.-P. (2010). Developing three-dimensional models of putative-folding intermediates of the HDV ribozyme. Structure. DOI
• Brosseau, J.-P., Lucier, J.-F., Lapointe, E., Durand, M., Gendron, D., Gervais-Bird, J., Tremblay, K., Perreault, J.-P., Elela, S.A. (2010). High-throughput quantification of splicing isoforms. RNA. DOI
• Bolduc, F., Hoareau, C., St-Pierre, P., Perreault, J.-P. (2010). In-depth sequencing of the siRNAs associated with peach latent mosaic viroid infection. BMC Molecular Biology. DOI
• Soulière, M.F., Perreault, J.-P., Bisaillon, M. (2010). Insights into the molecular determinants involved in cap recognition by the vaccinia virus D10 decapping enzyme. Nucleic Acids Research. DOI
• Lévesque, M.V., Lévesque, D., Brière, F.P., Perreault, J.-P. (2010). Investigating a new generation of ribozymes in order to target HCV. Plos One. DOI
• Bergeron Jr., L., Perreault, J.-P., Elela, S.A. (2010). Short RNA duplexes guide sequence-dependent cleavage by human Dicer. RNA. DOI
• Dubé, A., Baumstark, T., Bisaillon, M., Perreault, J.-P. (2010). The RNA strands of the plus and minus polarities of peach latent mosaic viroid fold into different structures. RNA. DOI
• St-Pierre, P., Hassen, I.F., Thompson, D., Perreault, J.P. (2009). Characterization of the siRNAs associated with peach latent mosaic viroid infection. Virology. DOI
• Soulière, M.F., Perreault, J.-P., Bisaillon, M. (2009). Characterization of the vaccinia virus D10 decapping enzyme provides evidence for a two-metal-ion mechanism. Biochemical Journal. DOI
• Dubé, A., Bisaillon, M., Perreault, J.-P. (2009). Identification of proteins from Prunus persica that interact with peach latent mosaic viroid. Journal of Virology. DOI
• Reymond, C., Beaudoin, J.-D., Perreault, J.-P. (2009). Modulating RNA structure and catalysis: Lessons from small cleaving ribozymes. Cellular and Molecular Life Sciences. DOI
• Reymond, C., Bisaillon, M., Perreault, J.-P. (2009). Monitoring of an RNA multistep folding pathway by isothermal titration calorimetry. Biophysical Journal. DOI
• Robichaud, G.A., Perreault, J.-P., Ouellette, R.J. (2008). Development of an isoform-specific gene suppression system: The study of the human Pax-5B transcriptional element. Nucleic Acids Research. DOI
• Soulière, M.F., Perreault, J.-P., Bisaillon, M. (2008). Kinetic and thermodynamic characterization of the RNA guanylyltransferase reaction. Biochemistry. DOI
• Souliøre, M.F., Perreault, J.-P., Bisaillon, M. (2008). Magnesium-binding studies reveal fundamental differences between closely related RNA triphosphatases. Nucleic Acids Research. DOI
• Beaudoin, J.-D., Perreault, J.-P. (2008). Potassium ions modulate a G-quadruplex-ribozyme's activity. RNA. DOI
• Motard, J., Bolduc, F., Thompson, D., Perreault, J.-P. (2008). The peach latent mosaic viroid replication initiation site is located at a universal position that appears to be defined by a conserved sequence. Virology. DOI
• Lévesque, D., Brière, F.P., Perreault, J.-P. (2007). A modern mode of activation for nucleic acid enzymes. Plos One. DOI
• Nehdi, A., Perreault, J., Beaudoin, J.-D., Perreault, J.-P. (2007). A novel structural rearrangement of hepatitis delta virus antigenomic ribozyme. Nucleic Acids Research. DOI
• Asif-Ullah, M., Lévesque, M., Robichaud, G., Perreault, J.-P. (2007). Development of ribozyme-based gene-inactivations; The example of the hepatitis delta virus ribozyme. Current Gene Therapy. DOI
• Reymond, C., Ouellet, J., Bisaillon, M., Perreault, J.-P. (2007). Examination of the folding pathway of the antigenomic hepatitis delta virus ribozyme reveals key interactions of the L3 loop. RNA. DOI
• Lévesque, D., Beaudoin, J.-D., Roy, S., Perreault, J.-P. (2007). In vitro selection and characterization of RNA aptamers binding thyroxine hormone. Biochemical Journal. DOI
• Fekih Hassen, I., Massart, S., Motard, J., Roussel, S., Parisi, O., Kummert, J., Fakhfakh, H., Marrakchi, M., Perreault, J.P., Jijakli, M.H. (2007). Molecular features of new Peach Latent Mosaic Viroid variants suggest that recombination may have contributed to the evolution of this infectious RNA. Virology. DOI
• Lucier, J.-F., Perreault, J., Noël, J.-F., Boire, G., Perreault, J.-P. (2007). RTAnalyzer: A web application for finding new retrotransposons and detecting L1 retrotransposition signatures. Nucleic Acids Research. DOI
• Perreault, J., Perreault, J.-P., Boire, G. (2007). Ro-associated Y RNAs in metazoans: Evolution and diversification. Molecular Biology and Evolution. DOI
• Fiola, K., Perreault, J.-P., Cousineau, B. (2006). Gene targeting in the gram-positive bacterium Lactococcus lactis, using various delta ribozymes. Applied and Environmental Microbiology. DOI
• Lucier, J.-F., Bergeron, L.J., Brière, F.P., Ouellette, R., Elela, S.A., Perreault, J.-P. (2006). RiboSubstrates: A web application addressing the cleavage specificities of ribozymes in designated genomes. BMC Bioinformatics. DOI
• Elleuch, A., Khouaja, F.D., Hamdi, I., Bsais, N., Perreault, J.-P., Marrakchi, M., Fakhfakh, H. (2006). Sequence analysis of three citrus viroids infecting a single Tunisian citrus tree (Citrus, reticulata, Clementine). Genetics and Molecular Biology. DOI
• Nehdi, A., Perreault, J.-P. (2006). Unbiased in vitro selection reveals the unique character of the self-cleaving antigenomic HDV RNA sequence. Nucleic Acids Research. DOI
• Bergeron Jr., L., Reymond, C., Perreault, J.-P. (2005). Functional characterization of the SOFA delta ribozyme. RNA. DOI
• Landry, P., Perreault, J.-P. (2005). Identification of a peach latent mosaic viroid hairpin able to act as a dicer-like substrate. Journal of Virology. DOI
• Perreault, J., Noël, J.-F., Brière, F., Cousineau, B., Lucier, J.-F., Perreault, J.-P., Boire, G. (2005). Retropseudogenes derived from the human Ro/SS-A autoantigen-associated hY RNAs. Nucleic Acids Research. DOI
• Bergeron, L.J., Perreault, J.-P. (2005). Target-dependent on/off switch increases ribozyme fidelity. Nucleic Acids Research. DOI
• Pelchat, M., Perreault, J.-P. (2004). Binding site of Escherichia coli RNA polymerase to an RNA promoter. Biochemical and Biophysical Research Communications. DOI
• Ouellet, J., Perreault, J.-P. (2004). Cross-linking experiments reveal the presence of novel structural features between a hepatitis delta virus ribozyme and its substrate. RNA. DOI
• D'Anjou, F., Bergeron, L.J., Larbi, N.B., Fournier, I., Salzet, M., Perreault, J.-P., Day, R. (2004). Silencing of SPC2 Expression Using An Engineered δ Ribozyme in the Mouse βTC-3 Endocrine Cell Line. Journal of Biological Chemistry. DOI
• Landry, P., Perreault, J.-P. (2004). The role of viroids in gene silencing: The model case of Peach latent mosaic viroid. Canadian Journal of Plant Pathology. DOI
• Bussière, F., Ledû, S., Girard, M., Héroux, M., Perreault, J.-P., Matton, D.P. (2003). Development of an efficient cis-trans-cis ribozyme cassette to inactivate plant genes. Plant Biotechnology Journal. DOI
• Elleuch, A., Marrakchi, M., Perreault, J.P., Fakhfakh, H. (2003). First report of Australian grapevine viroid from the Mediterranean region. Journal of Plant Pathology.
• Deschênes, P., Ouellet, J., Perreault, J., Perreault, J.-P. (2003). Formation of the P1.1 pseudoknot is critical for both the cleavage activity and substrate specificity of an antigenomic trans-acting hepatitis delta ribozyme. Nucleic Acids Research. DOI
• Bergeron Jr., L., Ouellet, J., Perreault, J.-P. (2003). Ribozyme-based gene-inactivation systems require a fine comprehension of their substrate specificities; the case of delta ribozyme. Current Medicinal Chemistry. DOI
• Pelchat, M., Rocheleau, L., Perreault, J., Perreault, J.-P. (2003). SubViral RNA: A database of the smallest known auto-replicable RNA species. Nucleic Acids Research. DOI
• Pelchat, M., Grenier, C., Perreault, J.-P. (2002). Characterization of a viroid-derived RNA promoter for the DNA-dependent RNA polymerase from Escherichia coli. Biochemistry. DOI
• Lévesque, D., Choufani, S., Perreault, J.-P. (2002). Delta ribozyme benefits from a good stability in vitro that becomes outstanding in vivo. RNA. DOI
• Bergeron, L.J., Perreault, J.-P. (2002). Development and comparison of procedures for the selection of delta ribozyme cleavage sites within the hepatitis B virus. Nucleic Acids Research. DOI
• Fiola, K., Perreault, J.-P. (2002). Kinetic and binding analysis of the catalytic involvement of ribose moieties of a trans-acting δ ribozyme. Journal of Biological Chemistry. DOI
• Elleuch, A., Fakhfakh, H., Pelchat, M., Landry, P., Marrakchi, M., Perreault, J.-P. (2002). Sequencing of Australian Grapevine Viroid and Yellow Speckle Viroid isolated from a Tunisian grapevine without passage in an indicator plant. European Journal of Plant Pathology. DOI
• Cote, F., Levesque, D., Perreault, J.-P. (2001). Natural 2',5'-phosphodiester bonds found at the ligation sites of peach latent mosaic viroid. Journal of Virology. DOI
• Pelchat, M., Coté, F., Perreault, J.-P. (2001). Study of the polymerization step of the rolling circle replication of peach latent mosaic viroid. Archives of Virology. DOI
• Poisson, V., Ménard, D.B., Frost, E., Perreault, J.-P. (2000). A Canadian isolate of hepatitis D (delta) virus. Canadian Journal of Gastroenterology. DOI
• Bussière, F., Ouellet, J., Côté, F., Lévesque, D., Perreault, J.P. (2000). Mapping in solution shows the peach latent mosaic viroid to possess a new pseudoknot in a complex, branched secondary structure. Journal of Virology. DOI
• Deschênes, P., Lafontaine, D.A., Charland, S., Perreault, J.-P. (2000). Nucleotides -1 to -4 of hepatitis delta ribozyme substrate increase the specificity of ribozyme cleavage. Antisense and Nucleic Acid Drug Development. DOI
• Pelchat, M., Lévesque, D., Ouellet, J., Laurendeau, S., Lévesque, S., Lehoux, J., Thompson, D.A., Eastwell, K.C., Skrzeczkowski, L.J., Perreault, J.P. (2000). Sequencing of peach latent mosaic viroid variants from nine North American peach cultivars shows that this RNA folds into a complex secondary structure. Virology. DOI
• Pelchat, M., Deschênes, P., Perreault, J.-P. (2000). The database of the smallest known auto-replicable RNA species: Viroids and viroid-like RNAs. Nucleic Acids Research. DOI
• Ananvoranich, S., Perreault, J.-P. (2000). The kinetics and magnesium requirements for the folding of antigenomic δ ribozymes. Biochemical and Biophysical Research Communications. DOI
• Roy, G., Ananvoranich, S., Perreault, J.-P. (1999). Delta ribozyme has the ability to cleave in trans an mRNA. Nucleic Acids Research. DOI
• Ananvoranich, S., Lafontaine, D.A., Perreault, J.-P. (1999). Mutational analysis of the antigenomic trans-acting delta ribozyme: The alterations of the middle nucleotides located on the P1 stem. Nucleic Acids Research. DOI
• Lafontaine, D.A., Ananvoranich, S., Perreault, J.-P. (1999). Presence of a coordinated metal ion in a trans-acting antigenomic delta ribozyme. Nucleic Acids Research. DOI
• Bussière, F., Lehoux, J., Thompson, D.A., Skrzeczkowski, L.J., Perreault, J.-P. (1999). Subcellular localization and rolling circle replication of peach latent mosaic viroid: Hallmarks of group A viroids. Journal of Virology. DOI
• Lafontaine, D.A., Deschênes, P., Bussière, F., Poisson, V., Perreault, J.-P. (1999). The viroid and viroid-like RNA database. Nucleic Acids Research. DOI
• Lafontaine, D.A., Mercure, S., Perreault, J.-P. (1998). Identification of a Crohn's disease specific transcript with potential as a diagnostic marker. Gut. DOI
• Mercure, S., Lafontaine, D., Ananvoranich, S., Perreault, J.-P. (1998). Kinetic analysis of δ ribozyme cleavage. Biochemistry. DOI
• Ananvoranich, S., Perreault, J.-P. (1998). Substrate specificity of δ ribozyme cleavage. Journal of Biological Chemistry. DOI
• Lafontaine, D.A., Mercure, S., Poisson, V., Perreault, J.-P. (1998). The viroid and viroid-like RNA database. Nucleic Acids Research. DOI
• Perreault, J.-P. (1997). Characterization of stable RNAs from the resected intestinal tissues of individuals with either Crohn's disease or ulcerative colitis. Biochemistry and Cell Biology. DOI
• Côté, F., Perreault, J.-P. (1997). Peach latent mosaic viroid is locked by a 2'5'-phosphodiester bond produced by in vitro self-ligation. Journal of Molecular Biology. DOI
• Mercure, S., Lafontaine, D., Roy, G., Perreault, J.-P. (1997). The self-catalytic RNA motifs of the hepatitis delta virus,Le mofif autocatalytique d'ARN du virus delta de l'hepatite humaine. Medecine Sciences. DOI
• Lafontaine, D., Mercure, S., Perreault, J.-P. (1997). Update of the viroid and viroid-like sequence database: Addition of a hepatitis delta virus RNA section. Nucleic Acids Research. DOI
• Bussière, F., Lafontaine, D., Perreault, J.-P. (1996). Compilation and analysis of viroid and viroid-like RNA sequences. Nucleic Acids Research. DOI
• Beadudry, D., Perreault, J.-P. (1995). An efficient strategy for the synthesis of circular RNA molecules. Nucleic Acids Research. DOI
• Bussière, F., Lafontaine, D., Côté, F., Beaudry, D., Perreault, J.P. (1995). Evidence for a model ancestral viroid. Nucleic Acids Symposium Series.
• Lafontaine, D., Beaudry, D., Marquis, P., Perreault, J.-P. (1995). Intra- and Intermolecular Nonenzymatic Ligations Occur within Transcripts Derived from the Peach Latent Mosaic Viroid. Virology. DOI
• Bussière, F., Perreault, J.P. (1995). On the road to a DNA-protein world. RNA New York N Y.
• Beaudry, D., Bussière, F., Lareau, F., Lessard, C., Perreault, J.-P. (1995). The RNA of both polarities of the peach latent mosaic viroid self-cleaves in vitro solely by single hammerhead structures. Nucleic Acids Research. DOI
• Perreault, J.-P., Altman, S. (1993). Pathway of activation by magnesium ions of substrates for the catalytic subunit of RNase P from Escherichia coli. Journal of Molecular Biology. DOI
• Perreault, J.-P., Altman, S. (1992). Important 2′-hydroxyl groups in model substrates for M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli. Journal of Molecular Biology. DOI
• Perreault, J.-P., Labuda, D., Usman, N., Yang, J.-H., Cedergren, R. (1991). Relationship between 2′-Hydroxyls and Magnesium Binding in the Hammerhead RNA Domain: A Model for Ribozyme Catalysis. Biochemistry. DOI
• Perreault, J.-P., Altman, S. (1991). The ribonuclease P.: A real RNA enzyme in vitro,LA RIBONUCLEASE P: UNE VERITABLE ENZYME A ARN IN VITRO. Medecine Sciences. DOI
• Bratty, J., Wu, T., Nicoghosian, K., Ogilvie, K.K., Perreault, J.-P., Keith, G., Cedergren, R. (1990). Characterization of a chemically synthesized RNA having the sequence of the yeast initiator tRNAMet. FEBS Letters. DOI
• Yang, J.-H., Perreault, J.-P., Usman, N., Labuda, D., Cedergren, R. (1990). Mixed DNA/RNA Polymers Are Cleaved by the Hammerhead Ribozyme. Biochemistry. DOI
• Perreault, J.-P., Wu, T., Cousineau, B., Ogilvie, K.K., Cedergren, R. (1990). Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity. Nature. DOI
• Wu, T., Ogilvie, K.K., Perreault, J.-P., Cedergren, R.J. (1989). Convenient Procedure for the Preparation of Specific Mixed DNA-RNA Polymers. Journal of the American Chemical Society. DOI
• PERREAULT, J.‐P., PON, R.T., JIANG, M.‐y., USMAN, N., PIKA, J., OGILVIE, K.K., CEDERGREN, R. (1989). The synthesis and functional evaluation of RNA and DNA polymers having the sequence of Escherichia coli tRNAfMet. European Journal of Biochemistry. DOI

Livres

• Adkar-Purushothama, C.R., Sano, T., Perreault, J.-P., Yanjarappa, S.M., Serio, F.D., Daròs, J.-A. (2023). Fundamentals of Viroid Biology. Fundamentals of Viroid Biology. DOI
• Adkar-Purushothama, C.R., Sano, T., Perreault, J.-P., Yanjarappa, S.M., Serio, F.D., Daròs, J.-A. (2023). Preface. Fundamentals of Viroid Biology. DOI
• Scarborough, R.J., Lévesque, M.V., Perreault, J.-P., Gatignol, A. (2014). Design and evaluation of clinically relevant SOFA-HDV ribozymes targeting HIV RNA. Methods in Molecular Biology. DOI
• Lévesque, M.V., Perreault, J.-P. (2012). Target-induced SOFA-HDV ribozyme. Methods in Molecular Biology. DOI

Chapitres de livre

• Perreault, J.-P., Bolduc, F., Adkar-Purushothama, C.R. (2023). Structure of viroids. Fundamentals of Viroid Biology. DOI
• Adkar-Purushothama, C.R., Di Serio, F., Perreault, J.-P., Sano, T. (2023). Viroid pathogenicity. Fundamentals of Viroid Biology. DOI
• Adkar-Purushothama, C.R., Perreault, J.-P., Sano, T. (2023). Viroid-induced RNA silencing and its secondary effect on the host transcriptome. Fundamentals of Viroid Biology. DOI
• Rouleau, S., Jodoin, R., Garant, J.-M., Perreault, J.-P. (2020). RNA G-Quadruplexes as Key Motifs of the Transcriptome. Advances in Biochemical Engineering Biotechnology. DOI
• Steger, G., Riesner, D., Maurel, M.-C., Perreault, J.-P. (2017). Viroid Structure. Viroids and Satellites. DOI
• Steger, G., Perreault, J.-P. (2016). Structure and Associated Biological Functions of Viroids. Advances in Virus Research. DOI
• Ananvoranich, S., Fiola, K., Ouellet, J., Deschênes, P., Perreault, J.-P. (2001). Kinetic analysis of bimolecular hepatitis delta ribozyme. Methods in Enzymology. DOI

Articles de conférence

• Elleuch, A., Marrakchi, M., Fakhfakh, H., Lévesque, D., Perreault, J.P., Bessais, N. (2004). Interactions between citrus cachexia viroid and closely related sequence variants may impair expression of cachexia symptoms. Acta Horticulturae. DOI

Propriétés intellectuelles

Brevets

• A target-dependant nucleic acid adaptor. USA 11/631.689 . (2013).
• Nucleic acid enzyme for RNA cleavage. USA 7,148,044 . (2007).
• Diagnosis of human inflammatory bowel diseases and nucleic acid reagents therefore. US 6,150,096. (2001).
• Nucleozymes. US 07/829,729. (1997).
• Diagnosis of human inflammatory bowel diseases and nucleic acid reagents therefore. 07/829,729. (1993).

Autres contributions

Présentations

• J.P. Perreault. (2022). Le Québec : une société du savoir en pleine mutation ponctuée de défis pour la jeunesse (invitas talk). Les Grands Rendez-vous de l'École de technologie supérieure, Montreal. Canada.
• J.P. Perreault. (2022). Les revues scientifiques, point nodal de la recherche mais point aveugle du financement. Se donner les moyens : d'une édition scientifique inclusive pour l'excellence. 89th Meeting Acfas. Colloque: Sciences ouvertes en français et responsabilités publiques, Quebec. Canada.
• J.P. Perreault. (2022). Prediction and conservation of RNA G-quadruplexes (invited talk). Seminar -- G4 Webinar (European organization; virtual presentation), Berlin. Allemagne.
• V. Naud, L.Valiquette, S. McMahon, J.P. Perreault. (2022). Pôle universitaire de santé numérique de l'Estrie (panel). Effervescence, Montréal. Canada.
• J.P. Perreault. (2022). Quels en seraient les enjeux pour le monde universitaire et quelles sont les pistes d'action prioritaires (round table). 89th Meeting Acfas (Quebec, Quebec). Colloque « Redéfinir l'excellence en recherche : pour une culture scientifique en phase avec les enjeux sociétaux », Québec. Canada.
• J.P. Perreault. (2021). Les codes cachés dans l'ARN : exemple des G-quadruplex (invited talk). 88ème Congrès de l'Acfas. En ligne. Canada.
• C.R. Adkar Purushothama, T. Sano, J.P. Perreault. (2021). RNA-mediaited targeting of viroid could potentially reduce the rate of infection in tomato plants (talk). 2021 Annual meeting of the Canadian Phytopathological Society (virtual meeting), Ontario. Canada.
• J.P. Perreault. (2021). The biology of peach latent mosaic viroid (invited talk). 10th ISHS International Peach Symposium. Grèce.
• J.P. Perreault. (2021). Viroid-derived small RNA induces early flowering in tomato plants by RNA silencing (invited talk). 3rd Annual Congress on Plant biology and Biotechnology (virtual conference), Osaka. Japon.
• J.P. Perreault, R. O'Reilly Runte. (2021). Where do Young Canadians turn for scientific information the can believe. Canadien Science Policy Conference, Ottawa. Canada.
• J.P. Perreault. (2020). Managing research sector during COVID-19 pandemia (invited talk). 37th Colloque of ADARUQ. Canada.
• J.P. Perreault. (2020). Use of AI for medical research (invited talk). Canada-Europe Research Collaboration - Mission of Canada to the European Union. Canada.
• J.P. Perreault. (2019). Characterization of protein capable of binding a G-quadruplex located in the 5'UTR of an mRNA (Invited speaker). 7th International Meeting on Quadruplex Nucleic Acids, Chang Chun. Chine.
• F. Bolduc, M.A. Turcotte, K. Bellemare, J.P. Perreault. (2019). Characterization of proteins capable of binding a G-quadruplex located in the 5'UTR of a mRNA. RNP network dynamics in development and disease -- EMBO, Ljubljana. Slovénie.
• F. Bolduc, M.A. Turcotte, K. Bellemare, J.P. Perreault. (2019). Characterization of proteins capable of binding a G-quadruplex located in the 5'UTR of an mRNA (Poster). RiboClub 20th Opening Meeting, Orford. Canada.
• J.P. Perreault. (2019). G-quadruplexes in the human transcriptome (Invited speaker). Seminar - Department of Chemistry, University of Pekin, Beijin. Chine.
• Rachel Jodoin, François Bolduc, J.P. Perreault. (2019). G4 of BAG-1 mRNA' 5'UTR and potentiel interacting RBPs (Invited speaker). 7th International Meeting on Quadruplex Nucleic Acids. Chine.
• J.P. Perreault. (2019). La nécessité de la vulgarisation scientifique à l'ère des « fakenews » (Invited speaker). 1ère édition de la Journée de la vulgarisation scientifique de Sherbrooke - Musée des sciences naturelles de Sherbrooke, Sherbrooke. Canada.
• J.P. Perreault. (2019). Role of institutions in supporting and developing RNA based research (invited speaker). 20th RiboClub Official Opening (Orford, Quebec), Orford. Canada.
• J.P. Perreault. (2018). Exploring the impact of G4 on the humain transcriptone (invited speaker). Seminar - Department of chemistry St-Louis University, St-Louis. États-Unis.
• J.P. Perreault. (2018). Exploring the impact of G4 on the human transcriptome (invited speaker). Seminar - Department of chemistry Queen's University, Kingston. Canada.
• J.P. Perreault. (2018). G-quadruplexes from the transcriptome associated to Parkinson disease. RiboClub montly session, Sherbrooke. Canada.
• J.P. Perreault. (2018). G-quadruplexes in the human transcriptome: identification quantification, location, function (Invited speaker). International Symposium BIONIC 2018 « Biology of non-canonical nucleic acids: from human to pathogens », Padoua. Italie.
• S. Belhamiti*, A. Ouangraoua, J.P. Perreault. (2018). Identification des G-quadruplexes dans le transcripytome humain. 24e Symposium scientifique du Département de biochimie, Université de Sherbrooke, sherbrooke. Canada.
• S. Belhamiti*, A. Ouangraoua, J.P. Perreault. (2018). Identification et caractérisation des G-quadruplexes dans le transcriptome humain. Symposium. Biochemistry Department, Université de Sherbrooke, Sherbrooke. Canada.
• J.P. Perreault. (2018). Impact of G quadruplexes of the molecular biology of the human cell (Invited speaker). Seminar - Institute of Biomedical Research of Barcelona, Barcelona. Espagne.
• J.P. Perreault. (2018). Les faussaires de la science -- (Invited talk - round table). Journée des sciences humaines 2018. Université de Sherbrooke, Sherbrooke. Canada.
• R. Jodoin*, J.P. Perreault. (2018). RNA G-quadruplex formation in the 5'UTR of nRNA associated with colorectal cancer (Talk). RiboClub montly session, Sherbrooke. Canada.
• J. M. Garant*, M. Scott, J.P. Perreault. (2018). RNA G-quadruplex prediction with the objective to investigate RNA translation regulation (Talk). RiboClub montly session, Sherbrooke. Canada.
• J.P. Perreault. (2018). The story of a donation that stimulate translational research (Invited speaker). Merck-FMHS research day, Sherbrooke. Canada.
• J.P. Perreault. (2018). What's up with the viroid structure compendium (Invited speaker). Viroid 2018, Valencia. Espagne.
• J.P. Perreault. (2017). A tool for training programs (Invited talk). CNRS Unité mixte Internationale in the Americas (Mexico City, Mexico), Mexico. Mexique.
• *C.R. Adkar Purushothama, J.P. Perrault (2017). (I was invited speaker by Dr A.T.M. Lima, C.R. Adkar Purushothama attended). (2017). Degradome studies reveals the wide spread derogation of endogenous mRNAs in viroid infected plants (Invited talk). 50th Brazilian Congress of Plant Pathology, Rio de Janiero. Brésil.
• J.P. Perreault. (2017). Exploration of RNA G-quadruplex as key motif of the transcriptome (Keynote talk). RiboWest, Vancouver. Canada.
• S. Rouleau, J. P. Perreault (I was invited by Dr L. Trantirek). (2017). RNA G-quadruplexes regulate the biogenesis and function of cancer related microRNAs (Invited talk). 6th International meeting on Quadruplex nucleic acid-G4thering, Prague. République tchèque.
• *R Jodoin, M Bisaillon, JP Perreault. (2016). Characterization of BAG-1, G-quadruplex, an mRNA involved in colorectal cancer (Talk). Symposium. Department of Biochemistry, Université de Sherbrooke, Sherbrooke. Canada.
• *C.R. Adkar Purushothama, J.P. Perrault. (2016). Degradome studies provide new insights into viroid pathogenicity. (Talk). 2016 Annual meeting of the Canadian Phytopathological Society (Moncton, New Brunswick), Moncton. Canada.
• J. P. Perreault. (2016). Développer une faculté de médecine et des sciences de la santé pro-active en recherche multidisciplinaire (Invited talk). 7e Colloque du LN2 (Magog, Québec), Magog. Canada.
• S. Rouleau, J. P. Perreault. (2016). G-quadruplexes regulate the biogenesis and function of cancer related microRNAs (Talk). RiboClub 2016, Sherbrooke. Canada.
• J.P. Perreault, M. Bisaillon. (2016). Job market and you ! (Invited talk). Riboclub (Orford, Québec), Orford. Canada.
• J.P. Perreault. (2016). RNA G-quadruplex as key motif of the human transcriptome (Invited talk). Seminar - Institute of cell Biology (Roma, Italy), Rome. Italie.
• J.P. Perreault. (2016). RNA G-quadruplex as key motifs of the transcriptome (Invited talk). Seminar - University of Tokyo, Tokyo. Japon.
• J.P. Perreault. (2016). Recent development in research and graduated studies at the Faculty of medicine and health sciences (Invited talk). Brazilian university leader in Canada (Sherbrooke, Québec), Sherbrooke. Canada.
• J.P. Perreault. (2016). Repliement des molécules d'ARN, une science (Invited talk). Seminar - Program of Medecine, Université de Sherbrooke, Sherbrooke. Canada.
• R Jodoin, JP Perreault. (2016). Rôles de G-quadruplex dans la traduction de l'ARNm BAG-1 impliqué dans le cancer colorectal (Invited talk). Career-day - CRCHUS, Sherbrooke, Sherbrooke. Canada.
• J.P. Perreault. (2016). Study of RNA G-quadruplex as an important motif of the transcriptome (Invited talk). Seminar - Department of Biochemistry, University of Alberta, Edmonton. Canada.
• R. Jodoin, J.P. Perreault. (2016). The G-quadruplex translation regulation of BAG-1; an mRNA involved in colorectal cancer (Invited talk). 17th RiboClub, Orford. Canada.
• P Thandapani, J Song, V Gandin, Y Cai, *S G Rouleau, *JM Garant, FM Boisvert, JP Perreault, I Topisirovic, S Richard. (2015). Aven recognition of RNA G-quadruplexes regulates translation of the Mixed Lineage Leukemia protooncogenes (Talk). 16th Riboclub Opening Session, Orford. Canada.
• Jean-Pierre Perreault. (2015). Definition of a RNA G-quadruplexe: an unresolved question (Invited talk). 5th International meeting on Quadruplex nucleic acids, Bordeaux. France.
• Jean-Pierre Perreault. (2015). Development of a viroid compendium (Invited talk). Viroid-2015, Ceske Budejovice. République tchèque.
• Jean-Pierre Perreault. (2015). Drug development and anatomy: two stengths of the Estrie Region (Invited talk). Seminar - Sherbrooke International Life Sciences Summit, Sherbrooke. Canada.
• Jean-Pierre Perreault. (2015). G-quadruplex: a key motif of the human transcriptome (Invited talk). Seminar - University of Debrecen, Budapest. Hongrie.
• *S Rouleau, *A Brumwell, *JP Sehi Glouzon, M Bisaillon, JP Perreault. (2015). G-quadruplexes and microRNAs : a dynamic duo (Short talk). 5th International meeting on Quadruplex Nucleic Acids, Bordeaux. France.
• *JM Garant, M Scott, JP Perreault. (2015). G4RNA, a database of G-quadruplex (Talk). 16th RiboClub, Orford. Canada.
• Jean-Pierre Perreault. (2015). L'exemple de la Faculté de médecine et des sciences de la santé - opportunités (Invited talk). Pratique de l'innovation, valorisation, entreprenariat - 3IT, Sherbrooke. Canada.
• (2015). Recents progrès dans l'étude des G-quadruplexes d'ARN comme motifs clés du transcriptome et utilisation en biologie de synthèse (Invited talk). Seminar - Institut Européen de Chimie et Biologie, Bordeaux.
• R J Scarborough, K L Adams, *M V Lévesque, A Daher, JP Perreault, A Gatignol. (2015). Ribozymes and siRNAs targeting the Gag RNA of HIV for gene and drug therapy (Talk). 16th RiboClub Opening Session, Orford. Canada.
• (2015). Special panel on Génomique et Biotechnologie : Innover ensemble pour la santé de demain (Invited talk). 9e Forum de l'industrie et de la santé du Québec, Québec.
• Jean-Pierre Perreault. (2015). Structure of the RNA G-quadruplexes : potential target of the human transcriptome (Invited talk). Seminar - Faculty of Pharmacy, University of Toronto, Toronto. Canada.
• (2015). The switch from a classical faculty of medicine in terms of research to one of translational research (Invited talk). Seminar - CIHR - Institute of Nutrition, metabolism and diabetes. Advisory board at Sherbrooke, Sherbrooke.
• Jean-Pierre Perreault. (2015). Viroid structure (Invited talk). Seminar - Institut National de Recherche Avancée, Biologie du Fruit et Pathologie, Bordeaux. France.
• Jean-Pierre Perreault. (2014). Impact des motifs G-quadruplexes sur le transcriptome (Invited talk). Seminar - Centre Robert-Cedergren de l'Université de Montréal, Montréal. Canada.
• Jean-Pierre Perreault. (2014). Impact des motifs G-quadruplexes sur le transcriptome humain (Invited talk). Seminar - Musée national des sciences naturelles de France, Paris. France.
• Jean-Pierre Perreault. (2014). Impact of G-quadruplex motifs on the transcriptome (Invited talk). Seminar - Manitoba Group of protein structure, University of Winnipeg, Winnipeg. Canada.
• Jean-Pierre Perreault. (2014). Impact of RNA G-quadruplexes on the human transcriptone (Invited talk). Seminar - Institut Curie, Paris, Paris. France.
• Jean-Pierre Perreault. (2012). Impact of G-quadruplex structures on the human transcriptome (Invited talk). 10th International Congress on Cell Biology and the XVI Meeting of the Brazilian Society for Cell Biology, Rio de Janeiro. Brésil.
• Jean-Pierre Perreault. (2012). Modulation of the HDV Ribozyme with aptamers that respond to Boolean Logic gates (Invited talk). Canadian Society of Chemistry 2012, Edmonton. Canada.
• Jean-Pierre Perreault. (2012). Étude du sentier de repliement d'un ARN catalytique et ingénierie moléculaire (Invited talk). Seminar - Université de Montpellier 1. Hôpital de St-Éloi, Montpellier. France.

Affiches pour une conférence

• M.A. Turcotte, J.P. Perreault. (2021). Characterization of the RNA G-quadruplex fols in the neuronal cell line U87MG using BioTASQ (poster). Pacifichem 2021 (virtual meeting), Hawaii. États-Unis.
• M.A. Turcotte, F. Bolduc, M. Bisaillon, J.P. Perreault. (2021). Characterization with BioTASQ of the RNA G-quadruplex fold in the neuronal cell line U87MG (poster). RiboClub 22th Opening Meeting (virtual meeting), Orford. Canada.
• A. Vannatelli, A. Ouangraoua, J.P. Perreault. (2021). G-quadruplex prediction and conservation do not only depend on GC content (poster). RiboClub 22th Opening Meeting (virtual meeting), Orford. Canada.
• A. Vannutelli, A. Ouangraoua, J.P. Perreault. (2021). G4 Conservation and abundance money all living Kingdom (poster). Pacifichem 2021 (virtual meeting), Haiwai. États-Unis.
• L. Guého, F. Bolduc, J.P. Perreault. (2021). Un G-quadruplex d'ARN de la région 3 non traduite du gène du FXR1 associé au retard mental recrute des protéines (poster). Congrès de l'Acfas (rencontre virtuelle), Sherbrooke. Canada.
• P. Lejault, M. Bisaillon, J.P. Perreault. (2021). rG4 Structure ULK3 : a modulator of alternative splicing upon viral infection (poster). RiboClub 22th Opening meeting (virtual meeting), Orford. Canada.
• J. Vencic, M. Scott, J.P. Perreault. (2020). Distribution of G-quadruplexes in the human transcriptome of the nervous system (Poster). Intelligent Systems for Molecular Biology (virtual meeting). Suisse.
• M.A. Turcotte, J.P. Perreault. (2020). G-quadruplex RNA-binding protein that regulates the translation of genes relates to Parkinson's disease (Poster). RNA meeting (virtual meeting), Vancouver. Canada.
• A. Vannutelli, A. Ouangraoua, J.P. Perreault. (2020). G-quadruplexes conservation in transcriptomes (Poster). Annual Meeting of The Society for Molecular biology and Evolution, Quebec. Canada.
• A. Vannutelli, J.M. Garant, A. Ouangraoua, J.P. Perreault. (2019). G-quadruplexes evolution in transcriptomes. ISMB/ECCB 2019, Basel. Suisse.
• M.A. Turcotte, J.M. Garant, H. Cossette-Roberge, J.P. Perreault. (2019). Identification de RBPs liant les G-quadruplexes de PRKN et VP35. 48e Journée scientifique de la Faculté de médecine et des sciences de la santé, Sherbrooke. Canada.
• M.A. Turcotte, J.M. Garant, H. Cossette-Roberge, J.P. Perreault. (2019). Identification de RBPs liants les G-quadruplexes de PRKN et VP35. Journée Phare 2019, Orford. Canada.
• M.A. Turcotte, J.P. Perreault. (2019). Identification de partenaires protéiques des G-quadruplexes de PRKN et VPR35. Journée Phare 2019, Orford. Canada.
• M.A. Turcotte, J.M. Garant, J.P. Perreault. (2019). Identification of RBPs able to bind PRKN and VPS35 RNA G-quadruplex. RiboClub 20th Opening Meeting, Orford. Canada.
• L. Guého, F. Bolduc, J.P. Perreault. (2019). Un G-quadruplex d'ARN de la région 3' non traduite du gène de FXR1, associé au retard mental, recrute des protéines. Journée Phare 2019, Orford. Canada.
• A. Vannutelli, J.M. Garant, J.P. Perreault et A. Ouangraoua. (2019). Étude de l'évolution des motifs G-quadruplexes dans les transcriptomes. 48e Journée scientifique de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke, Sherbrooke. Canada.
• M.A. Turcotte, J.P. Perreault. (2018). G-quadruplexes involvement in neurodegenerative diseases. 19th RiboClub Official Opening, Orford. Canada.
• R. Jodoin, J.P. Perreault. (2018). G-quadruplexes located in the 5'UTR of mRNAs associated with colorectal cancer pathways share common features. 19th RiboClub Official Opening, Orford. Canada.
• S. Belhamiti, J.M. Garant, A. Ouangraoua, J.P. Perreault. (2018). Identification des G-quadruplexes dans le transcriptome humain. 47e Journée scientifiques de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke, Sherbrooke. Canada.
• H. Cossette-Roberge, M.A. Turcotte, R. Jodoin, J.P. Perreault. (2018). Les G-quadruplexes dans l'ARN messager des gènes associés au Parkinson. Journée scientifique du 1er cycle, Faculté de médecine et des sciences de la santé, Sherbrooke. Canada.
• J.M. Garant, R. Jodoin, M. S. Scott, J.P. Perreault. (2018). RNA G-quadruplex prediction to investigate a novel RNA regulation model. ISMB, Chicago. États-Unis.
• J.M. Garant, R. Jodoin, M.S. Scott, J.P. Perreault. (2018). RNA G-quadruplexes prediction to investigate a novel RNA regulation model. RECOMB-CG 2018, Orford. Canada.
• F. Bolduc, J.P. Perreault. (2018). SnRPA and YBX1 can modulate the expression level of BAG1 through binding of a G-quadruplex. 19th RiboClub Official Opening, Orford. Canada.
• R. Jodoin, M. Bisaillon, J.P. Perreault. (2017). A 5 UTR RNA G-quadruplex structure affects both the cap-dependent and independent translation of BAG-1, an nRNA involved in colorectal cancer. 6th International Meeting on Quadruplex nucleic acid-G4thering, Prague. République tchèque.
• R. Jodoin, M. Bisaillon, J.P. Perreault. (2017). A 5'UTR RNA G-quadruplexe structure affects the translation of BAG-1, an mRNA involved in colorectal cancer. 18th RiboClub Official Opening, Orford. Canada.
• J.M. Garant, M. Scott, J.P. Perreault (2017). Winner of the best poster of the G-quadruplex meeting. (2017). G4RNA screener a motif independent identification of potential RNA G-quadruplexes. 6th International Meeting on Quadruplex nucleic acid-G4thering, Prague. République tchèque.
• S. Belhamiti, J.M. Garant, A. Ouangraoua, J.P. Perreault. (2017). Identification and characterization of G-quadruplexes in transcriptomes. 18th RiboClub Official Opening, Orford. Canada.
• J.M. Garant, M. Scott, J.P. Perreault. (2017). Identification de G-quadruplexes d'ARN potentiels sans definition de motif par G4RNA screener. 46e Journée scientifique de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke, Sherbrooke. Canada.
• M.A. Turcotte, F. Bolduc, J.P. Perreault. (2017). Investigation of proteins interacting with RNA G-quadruplexes located in the 5'UTR. Journée scientifique du 1er cycle, Faculté de médecine et des sciences de la santé, Sherbrooke. Canada.
• F. Bolduc, M.A. Turcotte, J.P. Perreault. (2017). Investigation of proteins interacting with RNA G-quadruplexes located in the 5'UTR. 18th RiboClub Annual Opening, Orford. Canada.
• S. Rouleau, A. Brumwell, J.P. Sehi Glouzon, M. Bisaillon, J.P. Perreault. (2017). Les G-quadruplexes régulent la biogénèse et la fonction de microARN liée au cancer. 46e Journée scientifique de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke, Sherbrooke. Canada.
• J.M. Garant, J.P. Perreault, M.S. Scott. (2017). Motif independent identification of potential RNA G-quadruplexes by G4RNA screener. 18th RiboClub Annual Opening, Orford. Canada.
• C.R. Adkar-Puroshothama, J.P. Perreault. (2017). Role of RNA-dependent RNA polymerase 6 in viroid pathogenesis. 18th RiboClub Official Opening, Orford. Canada.
• J.P. Perreault. (2017). Viroid evolution and adaptation during a plant infection. 18th RiboClub Annual Opening, Orford. Canada.
• *T. Giguère, *J.P. Glouzon, J.P. Perreault. (2016). A viroid structural compendium. RNA 2016 (Kyoto, Japan), Kyoto. Japon.
• T. Giguère, J.P. Perreault. (2016). A viroid structural compendium. 17th RiboClub, Orford. Canada.
• *S. Rouleau, *A. Brumwell, *J.P. Glouzon, J.P. Perreault. (2016). G-quadruplex structures effects on miRNA biogenesis and function (Poster). Journée scientifique de l'axe cancer du CRCHUS (Sherbrooke, Québec), Sherbrooke. Canada.
• S. Rouleau, A. Brumwell, J.P. Glouzon, J.P. Perreault. (2016). G-quadruplexes and microRNAs: the dynamic duo (Poster). Regulatory and non-coding RNAs meeting, New York. États-Unis.
• S. Rouleau, A. Brumwell, J.P. Glouzon, J.P. Perreault. (2016). G-quadruplexes regulated the biogenesis and functions of cancer related miRNAs (Poster). 17th RiboClub, Orford. Canada.
• F. Bolduc, J.M. Garant, F. Allard, J.P. Perreault. (2016). Irregular G-quadruplexes found in the unstranslated region of human mRNAs influence translation (Poster). 17th RiboClub, Orford. Canada.
• *R. Jodoin, M. Bisaillon, J.P. Perreault. (2016). Rôles du G-quadruplex dans la traduction de l'ARNm BAG-1 impliqué dans le cancer du colon. Journée scientifique de l'axe cancer du CRCHUS (Sherbrooke, Québec), Sherbrooke. Canada.
• R. Jodoin, M. Bisaillon, J.P. Perreault. (2016). The G-quadruplex translation regulation of BAG-1; an mRNA involved in colorectal cancer. American Association for Cancer Research 2016, San Francisco. États-Unis.
• R. Jodoin, M. Bisaillon, J.P. Perreault. (2016). The G-quadruplex translation regulation of BAG-1; an mRNA involved in colorectal cancer. 17th RiboClub, Orford. Canada.
• J. M. Garant, M.S. Scott, J.P. Perreault. (2016). Towards better identification of potential RNA G-quadruplexes using machine learning. 17th RiboClub, Orford. Canada.
• *JM Garant, M Scott, JP Perreault. (2016). Towards better identification of potential RNA G-quadruplexes using machine learning. GLBIO/CCBC meeting, Toronto. Canada.
• C.R. Adkar-Purushothama, J.P. Perreault. (2016). Understanding the complexity of viroid pathogenicity. 17th RiboClub, Orford. Canada.
• *C Levins, *R Jodoin, JP Perreault. (2015). Dertemining the formation and effects of G4s in proposed candidates. Journée scientifique du 1er cycle de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke, Sherbrooke. Canada.
• *T Giguère, *C R Adkar Purushothama, *F Bolduc, JP Perreault. (2015). Development of a viroid structural compendium. RNA 2015, Madison. États-Unis.
• *S Rouleau, *A Brumwell, *JP Sehi Glouzon, M Bisaillon, JP Perreault. (2015). G-quadruplexes and microRNAs: a dynamic duo. 5th International meeting on Quadruplex nucleic acid, Bordeaux. France.
• *JM Garant, M J Luce, M S Scott, JP Perreault. (2015). G4 RNA: and RNA G-quadruplex database. 16th RiboClub Opening session, Orford. Canada.
• *JM Garant, M S Scott, JP Perreault. (2015). G4RNA : Une base de données unique au G-quadruplexes d'ARN. 44e Journée scientifique de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke, Sherbrooke. Canada.
• *JM Garant, M J Luce, M S Scott, JP Perreault. (2015). G4RNA : an RNA G-quadruplex database. 5th International meeting on Quadruplex Nucleic Acids, Bordeaux. France.
• *R Jodoin, M Bisaillon, JP Perreault. (2015). The G-quadruplex translation regulation of BAG-I : an mRNA involved in colorectal cancer. 5th International meeting on Quadruplex Nucleic, Bordeaux. France.
• *A Brumwell, JP Perreault. (2015). The effect of G-quadruplex structures on microRNA binding. 10th annual research week, Sherbrooke. Canada.
• *L Bauer, M Tremblay, M Bisaillon, JP Perreault. (2015). The impact of G-quadruplex formation on RNA capping and translation. 16th RiboClub Opening session, Orford. Canada.
• *C R Adkar Purushothama, JP Perreault. (2015). Viroid infections induces early flowering by silencing FRIGIDA in tomato plants. 16th RiboClub Opening session, Orford. Canada.
• *J Normandeau-Guimond, *T Giguère, JP Perreault. (2015). Étude structurale des Apscaviroides. Journée scientifique du 1er cycle de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke, Sherbrooke. Canada.

Activités professionnelles

• 88e Congrès de l'Acfas - Du jamais su (en mode virtuel). Co-président. Sherbrooke, Québec, Canada. (2021).
• ACFAS. Président du conseil d'adminstration. Montreal, Quebec, Canada. (2021-2024).
• Symposium sur l’accès aux données et les systèmes de santé apprenant. Membre du comité organisateur. Longueuil (Campus de l'Université de Sherbrooke), Québec, Canada. (2018).
• 16th International Conference on Comparative Genomics, RECOMB-CG 2018. Membre du comité organisateur. Magog - Orford (Sherbrooke), Québec, Canada. (2018).
• Université de Sherbrooke. Member of the Radiosecurity Protection Committee. Sherbrooke, Quebec, Canada. (2017-2022).
• Bureau de Coopération Interuniversitaire. Membre du comité de la recherche. Montreal, Quebec, Canada. (2017-2025).
• Centre d’expertise en santé de Sherbrooke (CESS). Membre du conseil d'administration. Sherbrooke, Canada. (2017-2025).
• Centre de la recherche médicale de l'Université de Sherbrooke (CRMUS). Membre du conseil d'administration. Sherbrooke, Canada. (2017-2025).
• Accélérateur d’entreprises technologiques (ACET). Membre du conseil d'administration. Sherbrooke, Canada. (2017-2025).
• Calcul Québec. Membre du conseil d'administration. Montréal, Canada. (2017-2022).
• SAGE-Innovation. Créneau d'excellence de la démarche ACCORD, Ministère de l’Économie et de l’Innovation, Gouvernement du Québec. Membre du conseil d'administration. Sherbrooke, Québec, Canada. (2017).
• ACFAS. Chairman of the Selection Committee for the Prix ACFAS Léo-Pariseau. Montreal, Quebec, Canada. (2016).
• Association of Faculties of Medicine of Canada. Member of the research board. Ottawa, Canada. (2016-2017).
• ACFAS. Member of the Selection Committee for the Prix ACFAS Léo-Pariseau. Montreal, Quebec, Canada. (2015).
• International symposium : The challenges of biological research on aging in the 21th century: from cells to clinics. Co-organizer. Orford, Québec, Canada. (2014).
• Institut interdisciplinaire d'innovation technologique (3IT). Member of the scientific board. Sherbrooke, Québec, Canada. (2014-2018).
• Réseau de recherche interuniversitaire en sciences infirmières du Québec. Member of the Administration Council. Montréal, Canada. (2013-2017).
• CSSS-Chicoutimi. Member of the research committee. Chicoutimi, Québec, Canada. (2013-2017).
• Université de Sherbrooke. Membre du comité aviseur de la chaire en Télésanté. Sherbrooke, Quebec, Canada. (2013-2017).
• 10th International Congress on Cell Biology and the XVI Meeting of the Brazilian Society for Cell Biology. Chairman. Rio de Janeiro, Brésil. (2012).
• Sherbrooke International Life Sciences Summit. Member of the Steering Committee. Sherbrooke, Québec, Canada. (2012-2015).
• Viroid 2010 in association with the XV International Congress of Virology. Co-organizer. Sapporo, Japon. (2010).
• RiboClub Annual Meeting. Co-organizer. Orford, Québec, Canada. (2004-2016).
• RiboClub Annual Meeting. Co-organizer. Orford, Québec, Canada. (2001-2002).