Épisode 22 : Antibiothérapie orale dans les infections articulaires et osseuses (Étude OVIVA)

Diffusé le 28 février 2019

Dans cette 22e baladodiffusion, les Drs Luc Lanthier et Alex Carignan discutent d’antibiothérapie dans les infections articulaires et osseuses (étude OVIVA), en plus de réviser la littérature médicale de décembre 2018 et janvier 2019.

Quiz clinique (1 min 30), article principal (2 min 00), critique (20 min 47), autres articles (27 min 40), réponse au quiz clinique (33 min 38)

Référence principale

Li HK, Rombach I, Zambellas R, Walker AS, McNally MA, Atkins BL, et al. Oral versus Intravenous Antibiotics for Bone and Joint Infection. N Engl J Med. 2019;380(5):425-36. PubMed PMID: 30699315.


Articles associés

Boucher HW. Partial Oral Therapy for Osteomyelitis and Endocarditis - Is It Time? N Engl J Med. 2019 Jan 31;380(5):487-489. PubMed PMID: 30699312.

Thwaites GE, Scarborough M, Szubert A, Nsutebu E, Tilley R, Greig J, et coll. Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet. 2018;391(10121):668-678. PubMed PMID: 29249276.

Capsule méthodologique

Piaggio G, Elbourne DR, Altman DG, Pocock SJ, Evans SJW. Reporting of noninferiority and equivalence randomized trials: An extension of the CONSORT statement. JAMA. 2006; 295:1152-1160. PubMed PMID: 16522836.


Autres articles d'intérêt récents

Obadia JF, Messika-Zeitoun D, Leurent G, Iung B, Bonnet G, Piriou N, et al. Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation. N Engl J Med. 2018;379(24):2297-306. PubMed PMID: 30145927.

Stone GW, Lindenfeld J, Abraham WT, Kar S, Lim DS, Mishell JM, et al. Transcatheter Mitral-Valve Repair in Patients with Heart Failure. N Engl J Med. 2018;379(24):2307-18. PubMed PMID: 30280640.

Reid IR, Horne AM, Mihov B, Stewart A, Garratt E, Wong S, et al. Fracture Prevention with Zoledronate in Older Women with Osteopenia. N Engl J Med. 2018;379(25):2407-16. PubMed PMID: 30575489.

Krag M, Marker S, Perner A, Wetterslev J, Wise MP, Schefold JC, et al. Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU. N Engl J Med. 2018;379(23):2199-208. PubMed PMID: 30354950.

Girard TD, Exline MC, Carson SS, Hough CL, Rock P, Gong MN, et al. Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. N Engl J Med. 2018;379(26):2506-16. PubMed PMID: 30346242.

Yeh RW, Valsdottir LR, Yeh MW, Shen C, Kramer DB, Strom JB, et al. Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial. BMJ. 2018;363:k5094. PubMed PMID: 30545967.

Scully M, Cataland SR, Peyvandi F, Coppo P, Knobl P, Kremer Hovinga JA, et al. Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura. N Engl J Med. 2019;380(4):335-46. PubMed PMID: 30625070.

Zheng SL, Roddick AJ. Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. JAMA. 2019;321(3):277-87. PubMed PMID: 30667501.

Guide de pratique récents

Klarenbach S, Sims-Jones N, Lewin G, Singh H, Theriault G, Tonelli M, et al. Recommendations on screening for breast cancer in women aged 40-74 years who are not at increased risk for breast cancer. CMAJ. 2018;190(49):E1441-E51. PubMed PMID: 30530611.


Prasad K, Siemieniuk R, Hao Q, Guyatt G, O'Donnell M, Lytvyn L, et al. Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline. BMJ. 2018;363:k5130. PubMed PMID: 30563885.

Summary of Revisions: Standards of Medical Care in Diabetes-2019. Diabetes Care. 2019;42(Suppl 1):S4-S6. PubMed PMID: 30559226.

Bates SM, Rajasekhar A, Middeldorp S, McLintock C, Rodger MA, James AH, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy. Blood Adv. 2018;2(22):3317-59. PubMed PMID: 30482767.

Référence du quiz clinique

Messerli FH, Messerli AW, Lüscher TF. Eisenhower’s billion-dollar heart attack - 50 years later. N Engl J Med 2005;353(12):1205-1207. PubMed PMID: 16177247.

Lüscher TF, Obeid S. From Eisenhower's heart attack to modern management: a true success story! Eur Heart J. 2017 Nov 1;38(41):3066-3069. PubMed PMID: 29040468