The mission of the Université de Sherbrooke’s cancer research institute (Institut de recherche sur le cancer de l’Université de Sherbrooke (IRCUS)) is to promote multidisciplinary research focused on increasing knowledge in oncology to stimulate the development of innovative approaches to fight cancer and mitigate its impact on the quality of life of cancer patients.
Whether in basic, translational, and clinical research, these advances are leading to a number of discoveries and technologies that are currently shaking up cancer research and fostering the development of new treatment approaches, as well as the improvement of patient management and quality of life:
HEALTH PRECISION: Management or treatment adapted to each patient based on their cancer, values, and preferences.
Several research teams are studying how RNA and proteins contribute to the life of a cell, including its structural and regulatory roles. A disorder in their expressions can cause cancer. The “omics” technologies like genomics, transcriptomics, proteomics, metabolomics, and functional genomics allow for accurately establishing the complexity of disorders associated with each tumour and identifying new therapeutical targets often specific to each patient, or to different tumour clones in cancer developing in a patient.
Cancer involving organs of the digestive system represents a considerable burden due to its impact and low patient survival rate. There are several research teams devoted to improving gastrointestinal cancer screening, understanding how these types of cancer develop and the resistance issues associated with treatment, and identifying mechanisms causing their development to reduce their impact.
A better overall understanding of the biological processes allows for developing innovative approaches, such as improving the recognition of tumours by the immune system. Development in imaging also makes personalized cancer treatment possible. In relation to care, the patient is at the heart of the design and implementation of projects to improve clinical oncology health practices, in line with each patient’s values and preferences.