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Michelle Scott

Professeure, Faculté de médecine et des sciences de la santé

FMSS Dép. de biochimie et de génomique fonction.

Présentation

Sujet de recherche

Bioinformatique, Génomique, Acides nucléiques, Mécanismes biologiques et biochimiques

Disciplines de recherche

Biologie et autres sciences connexes, Informatique

Mots-clés

analyse de séquençage de prochaine génération, apprentissage automatisé, ARN non-codant, bases de données biologiques, bio-informatique, cibles complémentaires des petits ARN, génomique, mécanismes moléculaires du cancer, motifs de ciblage, nucléole, protéines interagissant avec l'ARN (RBP), régulation de l'épissage alternatif, réseaux régulatoires, transcriptomique

Intérêts de recherche

Mes intérêts de recherche pour les prochaines années sont la caractérisation des petits ARN nucléolaires au niveau de leur abondance, leur biogénèse et leurs interacteurs, l'étude de leur rôle dans la régulation de l'expression des gènes et la caractérisation de ces molécules dans les cellules saines et les cellules cancéreuses, avec un emphase sur le cancer de l'ovaire. Nous nous intéressons également à l'importance des annotations dans les analyses transcriptomiques.

Centre de recherche

Centre de recherche du CHUS

Langues parlées et écrites

Anglais, Français

Diplômes

(2011). (Postdoctorat, Postdoc). University of Dundee.

(2005). (Doctorat, Doctorat en Sciences). McGill University.

(2000). (Maîtrise avec mémoire, Maîtrise en Sciences - Maîtrise). The University of Calgary.

(1998). (Baccalauréat, B.Sc). Université de Montréal.

Expérience académique

Full professor (department of biochemistry and functional genomics). (2021-). Université de Sherbrooke. Canada.

Associate member (computer science department). (2016-). Université de Sherbrooke. Canada.

Associate professor (department of biochemistry and functional genomics). (2016-). Université de Sherbrooke. Canada.

Assistant professor (department of biochemistry and functional genomics). (2011-2016). Université de Sherbrooke. Canada.

Prix et distinctions

  • (2025) Chercheur Boursier Senior -- Fellowship. Fonds de recherche du Québec - Santé (FRQS). (Prix).
  • (2021) Chercheur Boursier Junior 2 -- Fellowship. Fonds de recherche du Québec - Santé (FRQS). (Prix).
  • (2021) Prix RECMUS which recognizes the quality of supervision and the dedication of a professor of the Faculty of Medicine and Health Sciences of the UdeS (out of >600 professors). Université de Sherbrooke. (Prix).
  • (2021) Prix Tremplin: recognizing exceptional research contribution early in professoral career. Université de Sherbrooke. (Prix).
  • (2017) Invited oral presentation at the Matinée des Chercheurs Boursiers. Club de Recherches Cliniques du Québec. (Distinction).
  • (2017) Chercheur Boursier Junior 1 -- Fellowship. Fonds de recherche du Québec - Santé (FRQS). (Prix).
  • (2011) Caledonian Research Foundation Biomedical Personal Fellowship. Royal Society of Edinburgh. (Prix).
  • (2008) CIHR Postdoctoral fellowship. Instituts de recherche en santé du Canada. (Prix).
  • (2005) CIHR Canada Graduate Scholarship Doctoral Award. Instituts de recherche en santé du Canada. (Prix).
  • (2000) Alberta Heritage Foundation for Medical Research Studentship. Alberta Heritage Foundation for Medical Research. (Prix).
  • (2000) Natural Sciences and Engineering Research Council of Canada Studentship. Conseil de recherches en sciences naturelles et en génie (CRSNG). (Prix).
  • Dean's list for exceptional professoral performance (2015, 2016, 2017, 2018, 2019, 2020, 2021). Université de Sherbrooke. (Prix).

Financement

  • Subvention. (Obtenu). Cocandidat. Challenging the dogmas of monocistronic genes and pseudogenes using proteogenomics and systems biology approaches to better define the human proteome in health and diseases. Instituts de Recherche en Santé du Canada (IRSC). Project grant. 1 525 000 $. (2021-2026)
  • Subvention. (Obtenu). Cocandidat. Replacement of automated real-time PCR cluster. Conseil de Recherches en Sciences Naturelles et Génie du Canada (CRSNG). Research Tools and Instruments grant program. 143 679 $. (2021-2026)
  • Subvention. (Obtenu). Cocandidat. RNA Bioengineering and Innovation Network. Conseil de Recherches en Sciences Naturelles et Génie du Canada (CRSNG). CREATE. 1 050 000 $. (2018-2024)
  • Subvention. (Obtenu). Chercheur principal. Building the tools for accurate RNA-seq analysis of the coding and non-coding transcriptome. Conseil de Recherches en Sciences Naturelles et Génie du Canada (CRSNG). Discovery Grants. 300 000 $. (2018-2024)
  • Subvention. (Obtenu). Chercheur principal. Small nucleolar RNAs as regulators of gene expression. Instituts de Recherche en Santé du Canada (IRSC). Project Grant. 573 750 $. (2017-2022)
  • Subvention. (Obtenu). Candidat principal. Equipment grant: Transcriptomic profiling of non-coding nuclear small RNAs. Fondation Canadienne pour l'Innovation (FCI). John R. Evans Leaders Fund. 898 264 $. (2017-2022)
  • Subvention. (Obtenu). Cocandidat. Understanding the contribution of DICER and microRNAs to inflammatory arthritis. Instituts de Recherche en Santé du Canada (IRSC). Project grant - bridge funding. 100 000 $. (2021-2022)
  • Subvention. (Obtenu). Cochercheur. Characterization of Covid-19 infection in rheumatoid arthritis patients - the CoViD-in-RA project. Instituts de Recherche en Santé du Canada (IRSC). COVID-19 Rapid Research Funding Opportunity - Therapeutics. 502 775 $. (2020-2021)
  • Subvention. (Obtenu). Cochercheur. Early prediction of bone erosiveness in rheumatoid arthritis using miRNAs. Instituts de Recherche en Santé du Canada (IRSC). Project grant. 611 600 $. (2016-2021)
  • Bourse de recherche. (Obtenu). Candidat principal. FRQS Chercheur Boursier Junior 2 (Fellowship). Fonds de recherche du Québec - Santé (FRQS). Chercheurs boursiers. 295 451 $. (2017-2021)
  • Subvention. (Obtenu). Cochercheur. Comparative transcriptomics of RNA G-quadruplexes. Fonds de recherche du Québec - Nature et technologies (FRQNT). Projet d'équipe. 162 000 $. (2018-2021)
  • Subvention. (Obtenu). Chercheur principal. Targets and mechanisms for the degradation of mRNA mediated by small nucleolar RNAs. Fonds de recherche du Québec - Nature et technologies (FRQNT). Projet d'équipe. 161 072 $. (2018-2021)
  • Subvention. (Terminé). Cochercheur. miRNAs in pregnancy and gestational diabetes: origin and functions for clinical applications. Instituts de Recherche en Santé du Canada (IRSC). Project grants. 455 175 $. (2018-2021)
  • Subvention. (Terminé). Candidat principal. The 19th Annual Meeting of the RiboClub. Instituts de Recherche en Santé du Canada (IRSC). Planning and dissemination grant. 20 000 $. (2018-2019)
  • Subvention. (Terminé). Chercheur principal. Importance des petits ARN nucléolaires dans le cancer séreux de l'ovaire. Internal funding programme, CRCHUS. PAFI -Programme d'aide de financement interne. 25 000 $. (2017-2018)
  • Subvention. (Terminé). Cocandidat. Planning and dissemination grant: The Annual Riboclub Symposium. Instituts de Recherche en Santé du Canada (IRSC). Planning and Dissemination Grant– Institute Community Support. 10 000 $. (2017-2017)

Publications

Articles de revue

  • *Fafard-Couture E, *Bergeron D, Couture S, Abou Elela S, Scott MS. (2021). Annotation of snoRNA abundance across human tissues reveals complex snoRNA-host gene relationships. Genome Biology 22 (1), 172. (Article publié).
  • Dumont AA, Dumont L, *Zhou D, Giguère H, Pileggi C, Harper MA, Blondin DP, Scott MS, Auger-Messier M. (2021). Cardiomyocyte-specificSrsf3deletion reveals a mitochondrial regulatory role. FASEB Journal 35 (5), e21544. (Article publié).
  • *Simoneau J, *Dumontier S, Gosselin R, Scott MS. (2021). Current RNA-seq methodology reporting limits reproducibility. Briefings in Bioinformatics 22 (1), 140-145. (Article publié).
  • Chauvin A, *Bergeron D, *Vencic J, Lévesque D, Paquette B, Scott MS, Boisvert FM. (2021). Downregulation of KRAB zinc finger proteins in5-fluorouracil resistant colorectal cancer cells. NAR Cancer _ _. (Article soumis).
  • *Bergeron D, *Laforest C, *Carpentier S, *Calvé A, *Fafard-Couture É, *Deschamps-Francoeur G, Scott MS. (2021). Evolutionary mechanisms of snoRNAs affect familysize, genomic location and abundance regulation. BMC Genomics 22 (1), 414. (Article publié).
  • *Leblanc S, Brunet MA, Jacques JF, Lekehal AM, Duclos A, Tremblay A, Bruggeman-Gascon A, *Samandi S, Brunelle M, Cohen AA, Scott MS, Roucou X. (2021). Newfound coding potential of transcripts unveils missing members of human protein communities. BioRxiv _ _. (Article soumis).
  • Brunet MA, Lucier JF, Levesque M, *Leblanc S, Jacques JF, Al-Saedi HRH, Guilloy N, Grenier F, Avino M, Fournier I, Salzet M, Ouangraoua A, Scott MS, Boisvert FM, Roucou X. (2021). OpenProt 2021: deeper functional annotation of the coding potential of eukaryotic genomes. Nucleic Acids Research 49 (D1), D380-D388. (Article publié).
  • RNAcentral Consortium (which includes *P Bouchard-Bourelle and MS Scott representing the database snoDB). (2021). RNAcentral 2021: secondary structure integration, improved sequence search, and new member databases. Nucleic Acids Research 49 (D1), D212-D220. (Article publié).
  • Mendez M, Phantom Consortium, Scott MS, Hoffman MM. (2021). Unsupervised analysis of multi-experiment transcriptomic patterns with SegRNA identifies unannotated transcripts. BioRxiv _ _. (Article soumis).
  • *Nguyen HD, Allaire A, Bisaillon M, Diamandis P, Scott MS, Richer M. (2020). A machine learning analysis of a “normal-like” IDH-WT infiltrating glioma transcriptomic subgroup associated with prolonged survival reveals novel immune and neurotransmitter-related actionable targets. BMC Medicine 18 (1), 280. (Article publié).
  • *Simoneau J, Gosselin R, Scott MS. (2020). Factorial study of the RNA-seq computational workflow identifies biases as technical gene signatures. Nucleic Acids Research Genomics and Bioinformatics 2 (2), lqaa043. (Article publié).
  • *Deschamps-Francoeur G, *Simoneau J, Scott MS. (2020). Handling multi-mapped reads in RNA-seq. Computational and Structural Biotechnology Journal 18 1569-1576. (Article publié).
  • Lambert E, Babeu JP, *Simoneau J, Raisch J, Lévesque D, Jolibois E, Avino M, Scott MS, Boudreau F, Boisvert FM. (2020). Human Hepatocyte NuclearFactor 4-α encodes isoforms with distinct transcriptional functions. Molecular and Cellular Proteomics 19 (5), 808-827. (Article publié).
  • Stephens E, Roy M, Bisson M, *Nguyen HD, Scott MS, Boire G, Bouchard L, Roux S. (2020). Osteoclast signaling-targeting miR-146a-3p and miR-155-5p are downregulated in Paget's disease of bone. BBA Molecular Basis of Disease 1866 (10), 165852. (Article publié).
  • *Boivin V, *Reulet G, *Boisvert O, Couture S, Abou Elela S, Scott MS. (2020). Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA. Nucleic Acids Research 48 (5), 2271-86. (Article publié).
  • *Bergeron D, *Fafard-Couture E, Scott MS. (2020). Small nucleolar RNAs: continuing identification of novel members and increasing diversity oftheir molecular mechanisms of action. Biochemical Society Transactions 48 (2), 645-656. (Article publié).
  • Dubois ML, Meller A, *Samandi S, Brunelle M, Frion J, Toupin A, Brunet M, Beaudoin M, Jacques JF, Lévesque D, Scott MS, Lavigne P, Roucou X and Boisvert FM. (2020). UBB Pseudogene 4 encodes functional ubiquitin variants. Nature Communications 11 (1), 1306. (Article publié).
  • *Bouchard-Bourelle P, *Desjardins-Henri C, *Mathurin-St-Pierre D, *Deschamps-Francoeur G, *Fafard-Couture E, *Garant JM, Abou Elela S, Scott MS. (2020). snoDB: An Interactive Database of Human snoRNA Sequences, Abundance and Interaction. Nucleic Acids Research 48 (D1), D220-D225. (Article publié).
  • Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, *Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, Hughes TR, Morris QD, Scott MS, Krause H, Angers S, Blencowe BJ, and Cummins, CL. (2019). ARGLU1 is a transcriptional coactivator and splicing modulator important for stress hormone signaling and development. Nucleic Acids Research 47 (6), 2856-70. (Article publié).
  • *Deschamps-Francoeur G, *Boivin V, Abou Elela S and Scott MS. (2019). CoCo: RNA-seq Read Assignment Correction for Nested Genes and Multimapped Reads. Bioinformatics 35 (23), 5039-5047. (Article publié).
  • Lauzier A, Normandeau-Guimond J, Vaillancourt-Lavigueur V, *Boivin V, Charbonneau M, Rivard N, Scott M, Dubois C, Jean S. (2019). Colorectal cancer cells respond differentially to autophagy inhibition in vivo. Scientific Reports 9 (1), 11316. (Article publié).
  • *Simoneau J, Scott MS. (2019). In Silico Analysis of RNA-Seq Requires a More Complete Description of Methodology. Nat Rev Mol Cell Biol 20 (8), 451. (Article publié).
  • Brunet M, Brunelle M, Lucier JF, Delcourt V, Levesque M, Grenier F, *Samandi S, *Leblanc S, Aguilar JD, Dufour P, Jacques JF, Fournier I, Ouangraoua A, Scott M, Boisvert FM, Roucou X. (2019). OpenProt: A more comprehensive guide to explore eukaryotic coding potential and proteomes. Nucleic Acids Research 47 (D1), D403-D410. (Article publié).
  • Boudreault S, Armero VES, Scott MS, Perreault JP, Bisaillon M. (2019). The Epstein-Barr virus EBNA1 protein modulates the alternative splicing of cellular genes. Virology Journal 16 (1), 29. (Article publié).
  • *Boivin V, *Faucher-Giguère L, Scott MS, Abou Elela S. (2019). The cellular landscape of mid-size non-coding RNA. WIREs RNA 10 (4), e1530. (Article publié).
  • *Garant JM, Perreault JP. Scott MS. (2018). G4RNA screener webserver: User focused interface for RNA G quadruplex prediction. Biochimie 151 115-8. (Article publié).
  • *Boivin V, *Deschamps-Francoeur G, Scott MS. (2018). Protein coding genes as hosts for noncoding RNA expression. Seminars in Cellular and Developmental Biology 75 3-12. (Article publié).
  • *Boivin V, *Deschamps-Francoeur G, Couture S, Nottingham RM, *Bouchard-Bourelle P, Lambowitz AM, Scott MS, Abou Elela S. (2018). Simultaneous detection and relative quantification of coding and non-coding RNAs using a single sequencing reaction. RNA 24 (7), 950-65. (Article publié).
  • *Jammali S, Kuitche E, Rachati A, Belanger F, Scott MS, Ouangraoua A. (2017). Aligning coding sequences with frameshift extension penalties. Algorithms for Molecular Biology 12 10. (Article publié).
  • *Samandi S, Roy AV, Delcourt V, Lucier JF, Gagnon J, Beaudoin MC, Vanderperre B, Breton MA, Motard J, Jacques JF, Gagnon-Arsenault I, Fournier I, Ouangraoua A, Hunting DJ, Cohen AA, Landry CR, Scott MS, Roucou X. (2017). Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins. eLife _ e27860. (Article publié).
  • *Garant, JM Perreault, JP Scott, MS. (2017). Motif independent identification of potential RNA G-quadruplexes by G4RNA screener. Bioinformatics 33 (22), 3532-3537. (Article publié).
  • Victoria ES Armero, Marie-Pier Tremblay, Andréa Allaire, Simon Boudreault, Camille Martenon-Brodeur, Cyntia Duval, Mathieu Durand, Elvy Lapointe, Philippe Thibault, Maude Tremblay-Létourneau, Jean-Pierre Perreault, Michelle S Scott, Martin Bisaillon. (2017). Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas. PLoS ONE 12 (5), e0176880. (Article publié).
  • *Balthazar P, *Tucunduva DC, *Luce MJ, Scott MS. (2017). Widespread Pre-translational Regulation of the Inclusion of Signal Peptides in Human Proteins. Genomics 109 (2), 113-122. (Article publié).
  • Ono M, Yamada K, Bensaddek D, Afzal V, Biddlestone J, Ortmann B, Mudie S, *Boivin V, Scott MS, Rocha S, Lamond AI. (2016). Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1? Protein Replacement Human Cell Lines. PLoS ONE 11 (4), e0154759. (Article publié).
  • *Luce MJ *Akpawu AA *Tucunduva DC *Mason S Scott MS. (2016). Extent of pre-translational regulation for the control of nucleocytoplasmic protein localization. BMC Genomics 17 472. (Article publié).
  • Boudreault S, Martenon-Brodeur C, Caron M, *Garant JM, Tremblay MP, Armero VE, Durant M, Lapointe E, Thibault P, Tremblay-Letourneau M, Perreault JP, Scott MS, Lemay G, Bisaillon M. (2016). Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions. PLoS ONE 11 (9), e0161914. (Article publié).
  • Tremblay MP, Armero VE, Allaire A, Boudreault S, Martenon-Brodeur C, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Bisaillon M. (2016). Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma. BMC Genomics 17 683. (Article publié).
  • Nguyen D, Grenier St-Sauveur V, Bergeron D, *Dupuis-Sandoval F, Scott MS, Bachand F. (2015). A polyadenylation-dependent 3' end maturation pathway is required for the synthesis of the human telomerase RNA. Cell Reports 13 (10), 2244-57. (Article publié).
  • *Garant JM, *Luce MJ, Scott MS, Perreault JP. (2015). G4RNA: an RNA G-Quadruplex database. Database _ 1-5. (Article publié).
  • *Dupuis-Sandoval F, *Poirier M, Scott MS. (2015). The emerging landscape of small nucleolar RNAs in cell biology. Wiley Interdisciplinary Reviews RNA 6 (4), 382-97. (Article publié).
  • *Deschamps-Francoeur G, Garneau D, *Dupuis-Sandoval F, *Roy A, *Frappier M, Catala M, Couture S, *Barbe-Marcoux M, Abou-Elela S, Scott MS. (2014). Identification of discrete classes of small nucleolar RNA featuring different ends and RNA binding protein dependency. Nucleic Acids Research 42 (15), 10073-85. (Article publié).
  • Boisvert FM , Ahmad Y , Gierli?ski M , Charrière F , Lamont D , Scott M , Barton G , Lamond AI. (2012). A quantitative spatial proteomics analysis of proteome turnover in human cells. Molecular & cellular proteomics : MCP 11 (3), M111.011429. (Article publié).
  • Scott MS , Ono M , Yamada K , Endo A , Barton GJ , Lamond AI. (2012). Human box C/D snoRNA processing conservation across multiple cell types. Nucleic Acids Research 40 (8), 3676-88. (Article publié).
  • Scott MS , Ono M. (2011). From snoRNA to miRNA: Dual function regulatory non-coding RNAs. Biochimie 93 (11), 1987-92. (Article publié).
  • Ono M , Scott MS , Yamada K , Avolio F , Barton GJ , Lamond AI. (2011). Identification of human miRNA precursors that resemble box C/D snoRNAs. Nucleic Acids Research 39 (9), 3879-91. (Article publié).
  • Scott MS , Troshin PV , Barton GJ. (2011). NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins. BMC Bioinformatics 12 317. (Article publié).
  • Scott MS , Boisvert FM , Lamond AI , Barton GJ. (2011). PNAC: a protein nucleolar association classifier. BMC genomics 12 74. (Article publié).
  • Ono M , Yamada K , Avolio F , Scott MS , van Koningsbruggen S , Barton GJ , Lamond AI. (2010). Analysis of human small nucleolar RNAs (snoRNA) and the development of snoRNA modulator of gene expression vectors. Molecular biology of the cell 21 (9), 1569-84. (Article publié).
  • Scott MS , Boisvert FM , McDowall MD , Lamond AI , Barton GJ. (2010). Characterization and prediction of protein nucleolar localization sequences. Nucleic Acids Research 38 (21), 7388-99. (Article publié).
  • Jansen G , Lee AY , Epp E , Fredette A , Surprenant J , Harcus D , Scott M , Tan E , Nishimura T , Whiteway M , Hallett M , Thomas DY. (2009). Chemogenomic profiling predicts antifungal synergies. Molecular systems biology 5 338. (Article publié).
  • Scott MS , Avolio F , Ono M , Lamond AI , Barton GJ. (2009). Human miRNA precursors with box H/ACA snoRNA features. PLoS Computational Biology 5 (9), e1000507. (Article publié).
  • McDowall MD , Scott MS , Barton GJ. (2009). PIPs: human protein-protein interaction prediction database. Nucleic acids research 37 (Database), D651-6. (Article publié).
  • Han X , Feng X , Rattner JB , Smith H , Bose P , Suzuki K , Soliman MA , Scott MS , Burke BE , Riabowol K. (2008). Tethering by lamin A stabilizes and targets the ING1 tumour suppressor. Nature cell biology 10 (11), 1333-40. (Article publié).
  • Scott MS , Barton GJ. (2007). Probabilistic prediction and ranking of human protein-protein interactions. BMC Bioinformatics 8 239. (Article publié).
  • Kislinger T , Cox B , Kannan A , Chung C , Hu P , Ignatchenko A , Scott MS , Gramolini AO , Morris Q , Hallett MT , Rossant J , Hughes TR , Frey B , Emili A. (2006). Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling. Cell 125 (1), (Article publié).
  • Scott MS , Oomen R , Thomas DY , Hallett MT. (2006). Predicting the subcellular localization of viral proteins within a mammalian host cell. Virology journal 3 (Article publié).
  • Scott MS , Perkins T , Bunnell S , Pepin F , Thomas DY , Hallett M. (2005). Identifying regulatory subnetworks for a set of genes. Molecular & cellular proteomics : MCP 4 (5), (Article publié).
  • Larocque D , Galarneau A , Liu HN , Scott M , Almazan G , Richard S. (2005). Protection of p27(Kip1) mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation. Nature neuroscience 8 (1), (Article publié).
  • Scott MS , Calafell SJ , Thomas DY , Hallett MT. (2005). Refining protein subcellular localization. PLoS computational biology 1 (6), (Article publié).
  • Scott MS , Thomas DY , Hallett MT. (2004). Predicting subcellular localization via protein motif co-occurrence. Genome research 14 (10A), (Article publié).
  • Scott M , Lu G , Hallett M , Thomas DY. (2004). The Hera database and its use in the characterization of endoplasmic reticulum proteins. Bioinformatics (Oxford, England) 20 (6), (Article publié).
  • Vieyra D , Loewith R , Scott M , Bonnefin P , Boisvert FM , Cheema P , Pastyryeva S , Meijer M , Johnston RN , Bazett-Jones DP , McMahon S , Cole MD , Young D , Riabowol K. (2002). Human ING1 proteins differentially regulate histone acetylation. The Journal of biological chemistry 277 (33), (Article publié).
  • Scott M , Bonnefin P , Vieyra D , Boisvert FM , Young D , Bazett-Jones DP , Riabowol K. (2001). UV-induced binding of ING1 to PCNA regulates the induction of apoptosis. Journal of cell science 114 (Pt 19), (Article publié).
  • Scott M , Boisvert FM , Vieyra D , Johnston RN , Bazett-Jones DP , Riabowol K. (2001). UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences. Nucleic acids research 29 (10), 2052-8. (Article publié).

Chapitres de livre

  • Scott, MS. (2012). Diversity, overlap and relationships in the small RNA landscape. Mallick and Ghosh. Regulatory RNAs: Basics, Methods and Applications (1-8). Allemagne : Springer-Verlag. (Article publié).

Ressources en ligne

  • Boivin V, Deschamps-Francoeur G, Scott MS. (2017). CoCo: Count Corrector for embedded and multi-mapped genes. Site Web.
  • Garant JM, Perreault JP, Scott MS. (2017). G4RNA screener: a tool for the prediction of RNA G-quadruplexes. Site Web.
  • Tran Y, Luce MJ, Garant JM, Scott MS. (2017). S2D2: Sherbrooke Spliced Domain Detector. Site Web.
  • Bouchard-Bourelle P, Mathurin-St-Pierre D, Garant JM, Boivin V, Deschamps-Francoeur G, Scott MS. (2017). snoDB: database for human snoRNAs. Site Web.
  • Garant JM, Luce MJ, Scott MS, Perreault JP. (2015). G4RNA: an RNA G-quadruplex database. Site Web.
  • Scott MS, Troshin P, Barton GJ. (2011). NoD: Nucleolar localization sequence detector. Site Web.
  • McDowall M, Scott MS, Barton GJ. (2008). PIPs: protein-protein interaction predictor and database. Site Web.
  • Scott M, Hallett MJ, Thomas DY. (2003). Hera database. Site Web.

Articles de conférence

  • *Vencic J, Vannutelli A, Scott M, Perreault JP. (2020). Distribution of G-quadruplexes in the human transcriptome of the nervous systems. Intelligent Systems of Molecular Biology, Virtual Meeting. (Article publié).
  • *Nguyen HD, Scott MS, Richer M. (2020). Gaba and Glutamate matabolic pathways in the glioma regulation. Intelligent Systems of Molecular Biology, Virtual Meeting. (Article publié).
  • *Reulet G, Couture S, Abou Elela S, Scott MS. (2020). Improved structred RNA detection by unraveling RNA structures using TGIRT sequencing. Intelligent Systems of Molecular Biology, Virtual Meeting. (Article publié).
  • *Fafard-Couture, E, Couture S, Scott MS. (2020). Inferring snoRNA characteristics from their abundance profile in healthy human tissues (poster and oral). Intelligent Systems of Molecular Biology, Virtual Meeting. (Article publié).
  • *Reulet G, Couture S, Abou Elela S, Scott MS. (2020). Novel characterization of the S. cerevisiae transcriptome. RNA Society Meeting (virtual). (Article publié).
  • *Bergeron D, *Deschamps-Francoeur G, *Fafard-Couture E, Scott MS. (2020). Unravelling novel non-canonical snoRNA functions using RNA-RNA interaction networks. Intelligent Systems of Molecular Biology, Virtual Meeting. (Article publié).
  • *Faucher-Giguère L, *Roy A, Couture S, *Deschamps-Francoeur G, Scott MS, Abou Elela S. (2020). Upregulation of H/ACA snoRNAs promotes cell proliferation and tumour aggressivity in high grade serous carcinoma. RNA Society Meeting (virtual). (Article publié).
  • *Deschamps-Francoeur G, Scott MS. (2020). Using machine learning to predict box C/D snoRNA interactions. RNA Society Meeting (virtual). (Article publié).
  • *Deschamps-Francoeur G, Scott MS. (2020). snoGloBe: a gradient boosting machine for the prediction of box C/D snoRNA interactions. Intelligent Systems of Molecular Biology, virtual meeting. (Article publié).
  • *Nguyen HD, Scott MS, Richer M. (2019). A Machine Learning Analysis of TCGA Expression Data to Finding Signatures for 'Normal-like' IDH-WT Gliomas With A Longer Survival. **This abstract was chosen for an oral presentation and won the Morrison H Finlayson Award. Annual Meeting of the Canadian Association of Neuropathologists, Kingston, Ontario. (Article publié).
  • *Duval T, *Deschamps-Francoeur G, Scott MS. (2019). Analyse bio-informatique de données de séquençage à haut débit d'intéractions ARN-ARN impliquant des snoRNA. Journée Scientifique de la FMSS, Sherbrooke. (Article publié).
  • *Zhou D, Couture S, Scott MS, Abou Elela S. (2019). Benmarking proposal for Differential Splicing Detection Tools Using RNA-seq. Annual Meeting of the RiboClub, Orford. (Article publié).
  • *Fafard-Couture E, Couture S, Scott MS. (2019). Characterization of the human snoRNome through TGIRT-seq of six healthy tissues. Annual Meeting of the RiboClub, Orford. (Article publié).
  • *Nguyen HD, Allaire A, Scott MS, Richer M. (2019). Coding transcriptomic profiling of infiltrating IDH-wt gliomas and identification of prognosis biomarkers. Annual Meeting of the RiboClub, Orford. (Article publié).
  • *Nguyen HD, Allaire A, Scott M, Richer M. (2019). Discovery of new biomarkers associated to the human brain IDH-wt glioma. Toronto RNA Enthusiasts' Day. (Article publié).
  • Clément AA, Légaré C, Desgagné V, Poirier C, Scott M, Perron P, Hivert MF, Côté AM, Guérin R, Bouchard L. (2019). Identification de microARN impliqués dans les troubles hypertensifs de la grossesse. Journée scientifique du centre intersectoriel en santé durable (CISD), UQAC. (Article publié).
  • *Faucher-Giguère L, Scott MS, Abou Elela S. (2019). La surexpression des snoRNAs de type boîtes H/ACA favorise la progression et l’agressivité des cancers ovariens de haut grade. Journée Scientifique de la FMSS, Université de Sherbrooke. (Article publié).
  • *Reulet G, Couture S, Abou Elela S, Scott MS. (2019). Novel characterization of the S. cerevisiae transcriptome. Annual Meeting of the RiboClub, Orford. (Article publié).
  • *Deschamps-Francoeur G and Scott MS. (2019). Predicting canonical and non-canonical box C/D snoRNA interactions using machine learning. ISMB RNA COSI: Computational RNA Biology. **This abstract was chosen for an oral presentation and obtained a competitive CIHR travel award (1500$). (Article publié).
  • *Deschamps-Francoeur G, *Duval T, Scott MS. (2019). Predicting canonical and non-canonical box C/D snoRNA targets. Annual Meeting of the RiboClub, Orford. (Article publié).
  • *Zhou D, Couture S, Scott M, Abou Elela S. (2019). RBFOX2 splicing complex regulates alternative splicing with different binding modes and functional outcome. RiboWest. This abstract was chosen for an oral presentation and awarded a competitive travel grant (250$). (Article publié).
  • *Simoneau J, *Dumontier S, Gosselin R and Scott MS. (2019). RNA-seq methodological landscape : the ignored importance of the choice of genome annotations. ISMB RNA COSI: Computational RNA Biology. This abstract was chosen for an oral presentation and was awarded a competitive travel grant (1100$ USD) from the ISCB and Eclipse. (Article publié).
  • *Simoneau J, Gosselin R, Scott MS. (2019). RNA-seq methodological landscape: underrepresented communities are at risk. RiboWest. (Article publié).
  • *Nguyen HG, Scott MS, Richer M. (2019). Search for new biomarkers related to human brain IDH-wt cancer. CSMB annual conference: Model systems in cancer research. This abstract was chosen for an oral presentation. (Article publié).
  • *Nguyen HD, Scott MS, Richer M. (2019). Search for new biomarkers related to human brain IDH-wt cancer. Symposium de l'axe inflammation/douleur, Université de Sherbrooke. This abstract was chosen for an oral presentation. (Article publié).
  • *Faucher-Giguère L, *Roy A, Couture S, *Deschamps-Francoeur G, Scott MS, Abou Elela S. (2019). Upregulation of H/ACA snoRNA promote cell survival and proliferation in high grade ovarian cancer. CSMB annual conference: Model systems in cancer research. This poster was awarded a competitive travel grant (250$). (Article publié).
  • *Bouchard-Bourelle P, *Mathurin St-Pierre D, *Deschamps-Francoeur G, *Boivin V, Couture S, *Garant JM, Abou Elela S and Scott MS. (2019). snoDB: Visualizing the Human snoRNome. ISMB RNA COSI: Computational RNA Biology. (Article publié).
  • *Desjardins-Henri C, *Bouchard-Bourelle P, Scott M. (2019). snoTHAW: un outil visuel et interactif pour représenter des données d'expression de snoRNAs. Journée Scientifique de la FMSS, Sherbrooke. (Article accepté).
  • *Simoneau J, Gosselin R, Scott MS. (2018). A graph-based approach to quantify gene annotation discrepancies. ISMB, High-throughput sequencing COSI, Chicago, USA. (Article publié).
  • R. Martinez-Contreras, N. Martinez-Montiel, J. Toutant, E, Lapointe, M. Durand, P. Thibault, M. Scott, N. Rivard, J. Carrier, J.B. Denault, R. Leduc and B. Chabot. (2018). Altered expression and alternative splicing of GPCR and EMAP transcripts in colorectal cancer. Gordon Research Conference on Post-Transcriptional Gene Regulation. (Article publié).
  • *Fafard-Couture E, *Boivin V, Scott MS. (2018). Analyse des snoRNA dans les ensembles de données TGIRT-seq provenant de différents tissus humains sains. Journée Phare. (Article publié).
  • *Bouchard-Bourelle P, *Mathurin-St-Pierre M, *Deschamsp-Francoeur G, Couture S, *Boivin V, *Garant JM, Abou Elela S, Scott MS. (2018). Annotation and characterization of snoRNAs with snoDB: an updated relational database. 19th annual meeting of the RiboClub. (Article publié).
  • *Bouchard-Bourelle P, *Mathurin-St-Pierre M, *Deschamsp-Francoeur G, Couture S, *Boivin V, *Garant JM, Abou Elela S, Scott MS. (2018). Annotation and characterization of snoRNAs with snoDB: an updated relational database. Ribosome Synthesis Meeting, Orford. (Article publié).
  • *Dumontier S, Collerette-Tremblay J, *Simoneau J, Dumont N, Scott M, Grandbois M, Bentzinger F. (2018). Caractérisation de la matrice extracellulaire de laminines dans la niche quiescente des cellules souches du muscle squelettique. Journée Scientifique FMSS. This poster won 2nd prize. (Article publié).
  • *Leblanc S, *Samandi S, Brunelle M, Brunet M, Scott M, Roucou X. (2018). Discovering novel proteins in interaction networks. HUPO conference, Orlando Florida. (Article publié).
  • *Faucher-Giguère L, Scott MS, Abou Elela A. (2018). High-grade ovarian cancer associated H/ACA snoRNAs repress apoptosis and promote cell survival. Journée Phare. This abstract was chosen for an oral presentation. (Article publié).
  • *Faucher-Giguère L, *Roy A, Couture S, Scott M, Abou Elela S. (2018). Identification and Validation of a Novel Class of snoRNA Markers of High Grade Ovarian Cancer. Bishop's University Research Day. (Article publié).
  • *Reulet G, *Berthoumieux M, Couture S, Abou Elela S, Scott MS. (2018). Improved sncRNA detection using TGIRT-Seq in S cerevisiae. 19th annual meeting of the RiboClub. (Article publié).
  • *Simoneau J, Gosselin R, Scott MS. (2018). Le séquençage de l'ARN, une technologie reproductible?. Journée Phare. This abstract was chosen for an oral presentation. (Article publié).
  • *Deschamps-Francoeur G, Scott MS. (2018). Predicting canonical and non-canonical box C/D snoRNA targets. 19th annual meeting of the RiboClub. (Article publié).
  • Deschamps-Francoeur G, Scott MS. (2018). Predicting canonical and non-canonical box C/D snoRNA targets. RiboClub, Orford. (Article publié).
  • *Deschamps-Francoeur G, Scott MS. (2018). Predicting canonical andnon-canonical snoRNA interactions. DeepLearn 2018, Genoa, Italy. This abstract was chosen for an oral presentation. (Article publié).
  • *Zhou, Scott, Abou Elela. (2018). RBFOX2 splicing complex regulates splicing with different binding modes and functional outcomes. 19th annual meeting of the RiboClub. (Article publié).
  • *Simoneau J, Gosselin R, Scott MS. (2018). RNA-seq, what should we do next?. 19th annual meeting of the RiboClub. This poster won third prize and the public's award (total 850$). (Article publié).
  • *Garant JM, Jodoin R, Scott MS, Perreault JP. (2018). RNA G-quadruplex prediction to investigate a novel RNA regulation model. ISMB. This poster was also chosen for an oral presentation. (Article publié).
  • N. Martinez-Montiel, R. Martinez-Contreras, J. Toutant, E, Lapointe, M. Durand, P. Thibault, M. Scott, N. Rivard, J. Carrier, J.B. Denault, R. Leduc and B. Chabot. (2018). Reprogramming splicing events in cancer using new small molecules and an innovative bifunctional oligonucleotide technology. Gordon Research Conference on Post-Transcriptional Gene Regulation. (Article publié).
  • *Boivin V, *Boisvert O, Couture S, Abou Elela S, Scott MS. (2018). Uncovering new non-coding RNA genes in human by reducing RNA structure bias in RNA-Seq. RECOMB-Comparative Genomics conference. This poster won 2nd prize (500$). (Article publié).
  • *Boivin V, Abou Elela S, Scott MS. (2018). Uncovering new snoRNAs and other small non-coding genes in human with TGIRT-Seq. ISMB, RNA COSI. This poster was chosen for an oral presentation and obtained a competitive travel award (750$). (Article publié).
  • *Simoneau J, Gosselin R, Scott MS. (2018). Un modèle graphique pour quantifier le manque de concordance des annotations. Journée Scientifique, FMSS, UdeS. (Article publié).
  • *Faucher-Giguère L, Scott MS, Abou Elela S. (2018). Upregulation of H/ACA snoRNAs promotes cell proliferation and tumour aggressivity. Ribosome Synthesis Meeting, Orford Québec. (Article publié).
  • *Tucunduva DC, *Balthazar P, *Luce MJ, Scott MS. (2018). Widespread pre-translational regulation of the inclusion of signal peptides in human proteins. Bishop's poster competition, Lennoxville. (Article publié).
  • *Jammali S, Scott MS, Ouangraoua A. (2017). Aligning Coding DNA sequence with frameshift extension penalties. RiboClub Annual Meeting, Orford, Canada. (Article publié).
  • R. Martínez-Contreras, N. Martínez-Montiel, J. Toutant, E. Lapointe, M. Durand, P. Thibault, M. Scott, N. Rivard, J. Carrier, J.B. Denault, R. Leduc, B. Chabot. (2017). Altered expression and alternative splicing of GPCR and EMAP transcripts in colorectal cancer. RiboClub annual meeting. (Article publié).
  • *Boisvert O, *Boivin V, Scott MS. (2017). Caractérisation d'ARN non-annotés détectés par TGIRT-seq. Journée Phare. (Article publié).
  • *Boivin V, *Deschamps-Francoeur G, Couture S, Nottingham R, *Bourelle-Bouchard P, Lambowitz AM, Scott MS, Abou Elela S. (2017). Choosing the best sequencing methodology for simultaneous detection and relative quantification of coding and non-coding RNA. 18th Annual Meeting of the RiboClub, Orford, Canada. (Article publié).
  • *Deschamps-Francoeur G, *Boivin V, *Dupuis-Sandoval F, Abou Elela S, Scott MS. (2017). CoCo: RNA-seq Read Assignment Correction for NestedGenes and Multimapped Reads. Intelligent Systems for Molecular Biology, Prague, Czech Republic. (Article accepté).
  • *Simoneau J, Gouraud A, Boissonneault G, Scott MS. (2017). Data-driven transcriptome - a CRAT story. 18th Annual Meeting of the RiboClub, Orford, Canada. (Article publié).
  • *Zhou D, Scott MS, Abou Elela S. (2017). Finding the codes for RBFOX2 regulation of alternative splicing. 18th Annual Meeting of the RiboClub, Orford, Canada. (Article publié).
  • *Deschamps-Francoeur G, Couture S, Abou Elela S, Scott MS. (2017). Functional Annotation of Human Box C/D snoRNAs. 18th Annual Meeting of the RiboClub, Orford, Canada. (Article publié).
  • *Berthoumieux M, Scott MS, Abou Elela S. (2017). Genome-wide identification of yeast RNase III binding sites reveals novel binding targets and cleavage independent mode of gene regulation. 18th Annual Meeting of the RiboClub, Orford, Canada. (Article publié).
  • *Garant JM, Perreault JP, Scott MS. (2017). Motif independent identification of potential RNA G-quadruplexes by G4RNA screener. 18th Annual Meeting of the RiboClub, Orford, Canada. (Article publié).
  • *Garant JM, Scott MS, Perreault JP. (2017). Motif independent identification of potential RNA G-quadruplexes by G4RNA screener. G4thering – 6th International Meeting on Quadruplex Nucleic Acids, Prague, Czech Republic. (Article publié).
  • *Leblanc S *Samandi S Scott M Roucou X. (2017). Randomized transcript sequences reveal conserved small open reading frames encoding peptides with some evidence of expression. Journée Scientifique de la FMSS. (Article publié).
  • N. Martínez-Montiel, R. Martínez-Contreras, J. Toutant, E. Lapointe, M. Durand, P. Thibault, M. Scott, N. Rivard, J. Carrier, J.B. Denault, R. Leduc, B. Chabot. (2017). Reprogramming splicing events in cancer using new small molecules and an innovative bifunctional oligonucleotide technology. 18th Annual Meeting of the RiboClub. (Article publié).
  • *Boivin V, *Deschamps-Francoeur G, Couture S, Nottingham R, *Bouchard-Bourelle P, Lambowitz AM, Scott MS, Abou Elela A. (2017). Simultaneous detection and relative quantification of coding and non-coding RNA. Intelligent Systems for Molecular Biology, Prague, Czech Republic. (Article accepté).
  • *Faucher-Giguère L, Couture S, *Roy A, Scott M, Abou Elela S. (2017). What is the mechanism behind SNORA19 and SNORA81 in ovarian cancer cells?. Journée Scientifique de la FMSS. (Article publié).
  • *Bourelle-Bouchard P, *Mathurin-St-Pierre D, *Boivin V, *Garant JM, *Deschamps-Francoeur G, Scott MS. (2017). snoDB: An Integrative Online snoRNA Database. RiboClub Annual Meeting, Orford, Canada. (Article publié).
  • *Roy A, *Dupuis-Sandoval F, Couture S, Nottingham R, Lambowitz A, Abou-Elela S, Scott MS. (2016). Characterization of small nucleolar RNAs (snoRNAs) in low malignant potential and high gradeserous ovarian cancer tissues by transcriptomics. 8th Canadian Conference on Ovarian Cancer Research, Niagara, Canada. (Article publié).
  • *Roy A, *Dupuis-Sandoval F, Couture S, Nottingham R, Lambowitz A, Abou-Elela S, Scott MS. (2016). Characterization of snoRNAs in low malignant potential and high grade serous ovarian cancer by transcriptomics. Canadian National Medical Student Research Symposium, Winnipeg, Canada. (Article publié).
  • *Samandi S, Lucier JF, Gagnon J, Cohen AA, Landry C, Scott MS, Roucou X. (2016). Deep transcriptome provides functional insights for thousands of novel proteins. Proteo Annual Symposium, Québec city, Canada. (Article publié).
  • *Boivin V, Couture S, Abou Elela S, Scott MS. (2016). Finding novel tragets of snoRNAs influencing alternative splicing and gene expression. RiboClub Annual Meeting, Orford, Canada. (Article publié).
  • *Boivin V, Couture S, Abou-Elela S, Scott MS. (2016). Finding novel tragets of snoRNAs influencing alternative splicing and gene expression. GLBIO/CCBC, Toronto, Canada. This poster won second prize. (Article publié).
  • *Deschamps-Francoeur, G. Couture, S. Abou Elela, S. Scott, M.S. (2016). Functional annotation of human box C/D snoRNAs. RiboClub Annual Meeting, Orford Canada. (Article publié).
  • Allard-Chamard H, Boire G, De Brum Fernandes A, Scott MS, Bouchard L, Roux S. (2016). Osteoclast microRNA profiles in erosive rheumatoid arthritis. ASBMR, Washington. (Article publié).
  • *Dupuis-Sandoval F, Couture S, Wu D, Nottingham R, Lambowitz A, Abou Elela S, Scott MS. (2016). Study of alternative snoRNAs characterization methods by deep sequencing. GLBIO/CCBC, Toronto, Canada. (Article publié).
  • *Garant, JM, Scott, MS, Perreault, JP. (2016). Towards better identification of potential RNA G-Quadruplexes using machine learning. RiboClub Annual Meeting, Orford, Canada. (Article publié).
  • *Garant JM, Scott MS, Perreault JP. (2016). Towards better identification of potential RNA G-Quadruplexes using machine learning. GLBIO/CCBC, Toronto, Canada. This poster won third prize. (Article publié).
  • *Boivin V, Couture S, Abou-Elela S, Scott MS. (2016). Trouver de nouvelles cibles des snoARN pouvant influencer l’épissage alternatif et l’expression génique. Journée Scientifique de la FMSS, Sherbrooke, Canada. (Article publié).
  • Boudreault S, *Garant JM, Thibault P, Durand M, Lapointe E, Scott MS, Lemay G, Bisaillon M. (2015). Alternative splicing modifications triggered by reovirus infection. Riboclub annual international meeting, Orford, Canada. (Article publié).
  • Nguyen D, Grenier-St-Sauveur V, Bergeron D, *Dupuis-Sandoval F, Scott MS, Bachand F. (2015). A polyadenylation-dependent 3’ end maturation pathway is required for the synthesis of the human telomerase RNA. 16th Annual Meeting of the RiboClub. (Article publié).
  • *Samandi S, Lucier JF, Scott MS, Roucou X. (2015). Exploring the function and evolution of proteins translated from unconventional protein coding sequences. Proteo, Quebec, Canada. (Article publié).
  • *Garant JM, *Luce MJ, Scott MS, Perreault JP. (2015). G4RNA: an RNA G-quadruplex database. Riboclub annual international meeting, Orford, Canada. (Article publié).
  • *Garant JM, *Luce MJ, Scott MS, Perreault JP. (2015). G4RNA : an RNA G-quadruplex database. 5th International Meeting on Quadruplex Nucleic Acids, Bordeaux, France. (Article publié).
  • *Garant JM, *Luce MJ, Scott MS, Perreault JP. (2015). G4RNA : an RNA G-quadruplex database. Journée scientifique de la FMSS, Sherbrooke, Canada. (Article publié).
  • *Boivin V, Abou Elela S, Scott MS. (2015). Investigating of the role of small nucleolar RNA (snoRNA) in the regulation of splicing. Riboclub annual international meeting, Orford, Canada. (Article publié).
  • *Boivin V Abou Elela S Scott MS. (2015). Investigating of the role of small nucleolar RNA (snoRNA) in the regulation of splicing. Journée Scientifique de la FMSS, Sherbrooke, Canada. (Article publié).
  • *Zhou D, Scott MS, Abou Elela S. (2015). RBFOX2 regulates pre-messenger RNA splicing using non-canonical binding motifs. Riboclub annual international meeting, Orford, Canada. (Article publié).
  • *Dupuis-Sandoval F, Wu D, Nottingham R, Lambowitz A, Abou Elela S, Scott MS. (2015). The effects of sequencing biases on ncRNAs and snoRNA profiling. Riboclub annual international meeting, Orford, Canada. (Article publié).
  • *Dupuis-Sandoval F, *Deschamps-Francoeur G, *Roy A, Abou Elela S, Scott MS. (2015). The expanding landscape of snoRNAs: a tale of the trials and tribulations ofdeep-sequencing structured small RNAs. Integrative RNA biology (ISMB), Dublin Ireland. (Article publié).
  • *Berthoumieux M, Abou Ellela S, Scott MS. (2015). Yeast Ribonuclease III Enhances Transcription Termination by Promoting the Dissociation of RNAPolymerase II Near Transcripts 3’ Ends. Riboclub annual international meeting, Orford, Canada. (Article publié).
  • *Frappier M, *Deschamps-Francoeur G, *Dupuis-Sandoval F, Garneau D, Abou Elela S, Scott MS. (2014). Analyse de séquençage à haut-débit pour caractériser la biogénèse des snoRNAs. Conférences Interdisciplinaires sur le Cancer, Sherbrooke, Canada. (Article publié).
  • *Garant J-M Scott MS Perreault J-P. (2014). G4RNAdb as a new tool to study RNA G-Quadruplexes. Riboclub, Orford, Canada. (Article publié).
  • *Zhou D, Gendron D, Scott MS, Abou Elela S. (2014). Identification of alternative splicing events regulated by the cancer associated splicing factors RBFOX2 and QKI. 15th Annual Meeting of the RiboClub. (Article publié).
  • *Deschamps-Francoeur G Garneau D *Dupuis-Sandoval F *Roy A *Frappier M Catala M Couture S *Barbe-Marcoux M Abou-Elela S Scott MS. (2014). Identification of discrete classes of small nucleolar RNA featuring different ends and RNAbinding protein dependency. RNA meeting, Québec, Canada. (Article publié).
  • *Akpawu AK, *Mason S, Scott MS. (2014). Regulation of protein localization at the level of transcription and splicing. Beyond the Genome, Boston, USA. (Article publié).
  • *Dupuis-Sandoval F, *Frappier M, *Roy A, *Deschamps-Francoeur G, Scott MS. (2014). snoRNA subclasses as agents of non canonical functions. Riboclub Annual International Meeting, Orford, Canada. (Article publié).
  • *Barbe-Marcoux M, Scott MS. (2013). Analyse de séquançage à haut débit pour caractériser les petits ARN dérivés snoRNA. Symposium d'ouverture des Conférences Interdisciplinaires sur le Cancer, Sherbrooke, Canada. (Article publié).
  • *Laperle J, *Deschamps-Francoeur G, *Barbe-Marcoux M, Scott MS. (2013). Possible role for stably accumulating snoRNA-derived small RNAs in the regulation of alternative splicing. Integrative RNA biology (ISMB), Berlin, Germany. (Article publié).
  • *Gosselin V, *Deschamps-Francoeur G, Scott MS. (2013). Prédiction des cibles des régions guide des snoRNAs de type «C/D box» avec RNAhybrid. Journée scientifique de la FMSS, Sherbrooke, Canada. (Article publié).
  • *Gosselin V, *Deschamps-Francoeur G, Scott MS. (2013). Prédiction des cibles des régions «guide» des snoRNAs de type «C/D box» avec RNAhybrid. Journée Phare, Orford, Canada. (Article publié).
  • *Akpawu AK, *Mason S, Scott MS. (2013). Study of the regulation of protein localisation by alternative splicing at the genome level. Riboclub annual meeting, Orford, Canada. (Article publié).
  • *Dupuis-Sandoval F, *Barbe-Marcoux M, Scott MS. (2013). snoRNA Biogenesis and Maturation. Riboclub annual meeting, Orford, Quebec. (Article publié).
  • *Laperle J, *Martin-Guay MO, Scott MS. (2012). Investigation of the role of stably accumulating snoRNA-derived small RNAs in the regulaiton of splicing. 72nd Harden Conference: RNA regulators of gene expression, Cambridge, England. (Article publié).
  • Scott MS, Ono M, Barton GJ, Lamond AI. (2011). Human box C/D snoRNA processing conservation across multiple cell types. RNA society annual meeting, Kyoto, Japan. (Article publié).
  • Scott MS, Boisvert F-M, McDowall MD, Lamond AI, Barton GJ. (2010). Characterisation of the nucleolar interaction network. Royal Society of Edinburgh Awards Ceremony. (Article publié).
  • Scott MS, Boisvert F-M, McDowall MD, Lamond AI, Barton GJ. (2010). Characterization and prediction of protein nucleolar localization sequences. ECCB, Ghent, Belgium. (Article publié).
  • McDowall MD, Scott MS, Barton GJ. (2010). Human protein-protein interaction prediction. International Society for Computational Biology Student Council Symposium, ISMB. (Article publié).
  • Scott MS, Avolio F, Ono M, Lamond AI, Barton GJ. (2009). miRNA precursors with snoRNA features. ISMB. (Article publié).
  • McDowall MD, Scott MS, Barton GJ. (2008). Prediction of human protein-protein interactions and the PIPs webserver. LASR conference, Leeds, UK. (Article publié).
  • Scott MS and Barton GJ. (2007). Prediction and ranking of human protein-protein interactions within a Bayesian framework. BioSysBio Conference, Manchester, UK. (Article publié).
  • Scott M, Thomas DY and Hallett M. (2005). Predicting subcellular localization via proteinmotif co-occurrence. Bioinformatics and Proteomics Keystone Symposia. (Article publié).
  • Scott M, Thomas DY and Hallett M. (2004). InterPro Motif Co-occurrence as a Basis for the Prediction of Subcellular Localization. IUBMB conference in Boston. (Article publié).
  • Scott M, Thomas DY and Hallett M. (2004). InterPro Motif Co-occurrence as a Basis for the Prediction of SubcellularLocalization. Canadian Proteomics Initiative conference. (Article publié).
  • Scott M, Hallett M, Thomas DY. (2003). Sequence based prediction of endoplasmic reticulum proteins. European Conference on Computational Biology. (Article publié).
  • Scott M, Hallett M, Thomas DY. (2003). Sequence based prediction of endoplasmic reticulum proteins using machinelearning approaches. Molecular and Cellular Proteomics. (Article publié).
  • Scott M, Boisvert FM, Parr E, Bazett-Jones DP, Riabowol K. (2000). The candidate tumor suppressor protein p33ING1b interacts with PCNA and translocates to the nucleoli in response to UV irradiation. Tumor Suppressors and Oncogenes Salk Institute Annual Meeting. (Article publié).
  • Bonnefin P, Scott M, Parr E, Boisvert FM, Riabowol K. (2000). physical association of p33ING1b with PCNA is induced by UV irradiation. Cancer Genetics and Tumor Suppressor Genes Meeting, Cold Spring Harbor. (Article publié).
  • Scott M, Boisvert FM, Vieyra D, Bazett-Jones DP, Riabowol K. (1999). The candidate tumor suppressor p33ING1b translocates to the nucleoli inresponse to UV irradiation. Alberta Cancer Board Annual Meeting. (Article publié).
  • Scott M, Jolicoeur P. (1998). Le facteur detranscription NF-kB et non la protéine Notch reconnaît le promoteur Cp responsablede l’activation du gène Hes-1. XVIIe Congrès des stagiaires d’été de la faculté de médecine. (Article publié).

Autres contributions

Cours enseignés

  • Analyse de données en biochimie; 2017,2018,2019. BCM430. (2016-01-01).Université de Sherbrooke. Canada. (1CR).
  • Biologie moléculaire du gène,2015,2016,2017. BIM501. (2015-05-07 à 2017-05-16).Université de Sherbrooke. Canada. (3CR).
  • Transcription et maturations post-transcriptionnelles; 2015,2017,2019. MCR716. (2015-03-26).Université de Sherbrooke. Canada. (2CR).
  • Introduction aux méthodes et données génomiques; 2015,2016,2017,2018,2019,2020. BFT708. (2015-01-06).Université de Sherbrooke. Canada. (1CR).
  • Sujets d'actualité en génomique; 2015,2016,2017,2018,2019,2020. BCH723. (2015-01-01).Université de Sherbrooke. Canada. (2CR).
  • Outils bio-informatiques, 2013,2014,2015,2016,2017,2018,2019,2020. BFT402. (2013-11-22).Université de Sherbrooke. Canada. (2CR).
  • Design Experimental,2013,2018. MCR715. (2013-11-08).Université de Sherbrooke. Canada. (2CR).
  • Génomique,2013,2014,2015. GNT518. (2013-09-17 à 2015-10-05).Université de Sherbrooke. Canada. (3CR).
  • Séminaires de biochimie;2013,2014,2015,2016,2017,2018. BCM402. (2013-06-05 à 2018-07-02).Université de Sherbrooke. Canada. (2CR).
  • Bio-informatique pour les sciences de la vie;2013,2014,2015,2016,2017,2018,2019,2020. BCH722. (2013-05-01).Université de Sherbrooke. Canada. (2CR).
  • Bio-informatique;2013,2014,2015,2016,2017,2018,2019,2020. BCM420. (2013-01-01).Université de Sherbrooke. Canada. (2CR).
  • Protéines et pathologies associées,2012,2013,2014,2015,2016,2018. BCH711. (2012-03-21 à 2018-03-15).Université de Sherbrooke. Canada. (2CR).

Gestion d'évènements

  • Session chair. (2012-2050) RiboClub monthly seminar, month of January (2014,2015,2016,2016,2017,2018,2019,2020,2021). (Séminaire).
  • Member of the organizing and scientific committees. Session chair. (2021) iRNA track of the Intelligent Systems for Molecular Biology (ISMB), held virtually. (Conférence).
  • Member of the organizing committee. (2020) iRNA track of the Intelligent Systems for Molecular Biology (ISMB), held virtually in July 2020. (Conférence).
  • Member of the organizing committee, organization of poster competition. (2019) 20th Annual RiboClub conference. (Conférence).
  • Member of the organizing committee. (2019) 20th RiboClub. (Conférence).
  • Member of the organizing and scientific committees. Session chair. (2019) RNA track of the Intelligent Systems for Molecular Biology (ISMB), held in Switzerland in July 2019. (Conférence).
  • Member of the organizing committee, session chair. (2019) CSMB 62nd Annual Conference: Model Systems in Cancer Research, Montréal. (Conférence).
  • Member of the organizing committee, poster competition organizer. (2018) RECOMB, Comparative Genomics satellite conference, Orford. (Conférence).
  • Member of the organizing committee, organization of poster competition. (2018) 19th Annual RiboClub conference, Orford. (Conférence).
  • Member of the scientific committee, session chair. (2018) Integrative RNA Biology, ISMB 2018, Chicago. (Conférence).
  • Organizer. (2018) Graduate student symposium of the Biochemistry Department, Sherbrooke. (Conférence).
  • Member of the organizing committee, organization of poster competition. (2017) 18th Annual RiboClub conference, Orford. (Conférence).
  • Organizer. (2017) Graduate student symposium of the Biochemistry Department, Sherbrooke. (Conférence).
  • Member of the organizing committee, organization of poster competition. (2016) 17th Annual RiboClub conference, Orford. (Conférence).
  • Organizer. (2016) Graduate student symposium of the Biochemistry Department, UdeSherbrooke. (Conférence).
  • Member of the organizing committee. (2015) 16th Annual RiboClub conference. (Conférence).
  • Organizer. (2015) Graduate student symposium of the Biochemistry Department, UdeSherbrooke. (Conférence).
  • Member of the organizing committee. (2014) 15th Annual RiboClub conference. (Conférence).
  • Co-organizer. (2014) Graduate student symposium of the Biochemistry Department, UdeSherbrooke. (Conférence).
  • Member of the organizing committee. (2013) 14th Annual RiboClub conference. (Conférence).
  • Member of the COSI task force, representating the Integrative RNA Biology group. International Society for Computational Biology, Communities of Special Interest (COSI) task force. (Association).

Activités de collaboration internationale

  • Researcher participating in the ENFIN European grant. Royaume-Uni.

Présentations

  • (2021). Le séquençage du transcriptome à haut débit et ses enjeux. ACFAS (Association francophone pour le savoir). Virtual
  • (2019). Characterizing the snoRNome through transcriptomics profiling and RNA-RNA interactomics. Dagstuhl 5-day Workshop on Advances and Challenges in Protein-RNA Recognition, Regulation and Prediction. Dagstuhl, Allemagne
  • (2019). Investigation of the extent of snoRNA cellular functionality by low structure bias sequencing, network and machine learning approaches. Invited speaker, Princess Margaret Cancer Seminar Series, Toronto. Toronto, Canada
  • (2019). Low structure bias expression profiling of human transcripts reveals new snoRNAs as well as annotated snoRNAs with canonical and non-canonical functional capacity. RNA Informatics 2019, Wellcome Genome Campus, Cambridge. Cambridge, Royaume-Uni
  • (2019). Low structure bias expression profiling of human transcripts reveals the snoRNA landscape. Bellairs Workshop on Mechanisms and evolution of post-transcriptional regulation. Holetown, Barbade
  • *Deschamps-Francoeur G, Scott MS. (2019). Predicting canonical and non-canonical box C/D snoRNA interactions using machine learning. ISMB. Basel, Suisse
  • *Simoneau J, Dumontier S, Gosselin R, Scott MS. (2019). RNA-seq methodological landscape : the ignored importance of the choice of genome annotations. ISMB. Basel, Suisse
  • (2018). A pan-transcriptome view of mid-size RNAs. RiboWest 2018 conference. Lethbridge, Canada
  • *Garant JM, Jodoin R, Scott MS, Perreault JP. (2018). RNA G-quadruplex prediction to investigate a novel RNA regulation model. ISMB. Chicago, États-Unis
  • (2018). Tissue-based map of the snoRNome. 19th annual RiboClub conference. Canada
  • *Boivin V, *Boisvert O, Couture S, Abou Elela S, Scott MS. (2018). Uncovering new non-coding RNA genes in human with TGIRT-seq. ISMB. Chicago, États-Unis
  • *Boivin V, *Boisvert O, Couture S, Abou Elela S, Scott MS. (2018). Uncovering new snoRNAs and other small non-coding genes in human with TGIRT-Seq. Ribosome Synthesis Meeting. Orford, Canada
  • (2017). Établissement d'outils pour comprendre le rôle oncogénique des petits ARN nucléolaires. Club de Recherches Cliniques du Québec, Orford. Orford, Canada
  • (2016). Alternative splicing regulation of pre-mRNA by small nucleolar RNAs. Splicing2016. Lisbon, Portugal
  • (2016). Small nucleolar RNAs as regulators of gene expression. RiboClub Annual Meeting. Orford, Canada
  • (2015). The expanding landscape of snoRNAs: a tale of deep-sequencing. Rendez-vous Génome Québec. Sherbrooke, Canada
  • (2015). The expanding landscape of snoRNAs: a tale of the trials and tribulations of deep-sequencing structured small RNAs. Institute of Genetics and Molecular Medicine, The University of Edinburgh. Edinburgh, Royaume-Uni
  • (2015). The expanding landscape of snoRNAs: a tale of the trials and tribulations of deep-sequencing structured small RNAs. Division of Computational Biology, College of Life Sciences, University of Dundee. Dundee, Royaume-Uni
  • (2014). Differential processing for human box C/D snoRNAs. Riboclub monthly session. Sherbrooke, Canada
  • (2014). Petits ARN dérégulés dans le cancer : une approche bio-informatique. Axe Cancer Monthly Seminar. Sherbrooke, Canada
  • (2013). Création d’un prédicteur bio-informatique pour identifier des motifs de ciblage protéique au nucléole. Computer Science department seminars. Sherbrooke, Canada
  • (2013). Non-canonical characteristics and functions for snoRNAs. RiboWest conference, Prince George. Prince George, Canada
  • (2013). Stably accumulating snoRNA-derived small RNAs in the regulation of alternative splicing. Integrative RNA Biology (within the Intelligent Systems for Molecular Biology conference), Berlin. Berlin, Allemagne
  • (2012). Non-canonical functions for snoRNAs. Riboclub monthly seminar. Sherbrooke, Canada
  • (2012). Recherche en bioinformatique. Retraite annuelle de l'axe Mère-Enfant, Faculté de Médecine, Université de Sherbrooke. North Hatley, Canada
  • (2012). Role of stably accumulating snoRNA-derived small RNAs in the regulation of splicing. Riboclub annual meeting. Orford, Canada
  • (2011). Novel functions for small nucleolar RNAs. Invited presentation at the Immunology Frontier Research Center, University of Osaka. Osaka, Japon
  • (2010). Bioinformatic characterisation of the nucleolus. Invited Seminar, Department of Biochemistry, University of Sherbrooke. Sherbrooke, Canada
  • (2010). Bioinformatic characterisation of the nucleolus. Department of Biochemistry Invited Seminar, McGill University. Montreal, Canada
  • (2010). Investigation and characterization of protein nucleolar localization sequences in eukaryotes. Division of Biological Chemistry and Drug Discovery Seminar Series, University of Dundee. Dundee, Royaume-Uni
  • (2010). Investigation of Nucleolar Localization Sequences. Joint Mathematical Biology-Computational Biology Seminar Series, University of Dundee. Dundee, Royaume-Uni
  • (2009). A tale of two RNAs: snoRNAs with miRNA capabilities. Invited Seminar, Biochemistry Department, McGill University. Montreal, Canada
  • (2009). A tale of two RNAs: snoRNAs with miRNA capabilities. Invited seminar, Biochemistry Department, University of Sherbrooke. Sherbrooke, Canada
  • (2009). Bioinformatic investigation of nucleolar protein association. Seminar Series, Division of Biological Chemistry and Drug Discovery, University of Dundee. Dundee, Royaume-Uni
  • (2007). Large-scale prediction of human protein-protein interactions and analysis in the context of the nucleolar subnetwork. McGill Centre for Bioinformatics Seminar Series, McGill University. Montreal, Canada
  • Scott M, Thomas DY and Hallett M. (2004). InterPro Motif Co-occurrence as a Basis for the Prediction of Subcellular Localization. IUBMB conference in Boston. Boston, États-Unis
  • (2004). The study/prediction of protein subcellular localization using the ER as model organelle. Postdoc recruitment seminar, Bioinformatics Research Group, University of Dundee. Dundee, Royaume-Uni
  • (2004). The study/prediction of protein subcellular localization using the ER as model organelle. 3rd annual Barbados Bioinformatics Workshop – The Bajan Proteome. Holetown, Barbade
  • (2003). Sequence Based Prediction of Endoplasmic Reticulum Resident Proteins. Seminar Series in Quantitative Biology, Centre for Nonlinear Dynamics in Physiology and Medicine, McGill University. Montreal, Canada
  • (1997). Le facteur de transcription NF-kB et non la protéine Notch reconnaît le promoteur Cp responsable de l’activation du gène Hes-1. XVIIe Congrès des stagiaires d’été de la faculté de médecine de l'Université de Montréal. Montreal, Canada