Langlois, Alexandra

Professeure, Faculté de médecine et des sciences de la santé
FMSS Département de pédiatrie

Coordonnées

Courriel


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Diplômes

(2018) Diplôme (Immunologie clinique et allergie). McGill University.

(2017) Diplôme (Pédiatrie générale). Université de Sherbrooke.

(2013) Diplôme (Doctorat en Medecine/Medicinae Doctor). Université de Sherbrooke.

Titres de compétence

Fellow of the Royal College of Physicians of Canada (FRCPC) - Allergy and clinical immunology. College Royal des Médecins et Chirurgiens du Canada.

Fellow of the Royal College of Physicians of Canada (FRCPC) - General Pediatrics. Collège Royal des Médecins et Chirurgiens du Canada.

Expérience académique

(2019) Assistant Professor. Université de Sherbrooke.

(2018) Sub-Investigator MILES Study - VIaskin Milk Phase 2b RCT. Université de Montréal.

(2018) Sub-Investigator PEOPLE - Viaskin Peanut long term extension study. Université de Montréal.

(2018) Sub-Investigator REALISE - Real-life safety study for Viaskin Peanut. Université de Montréal.

(2018-2019) Research Fellow. Université de Montréal.

(2017-2018) Chief Resident. McGill University Health Centre.

(2016-2018) Sub-Investigator for MILK GET FACTS study. The Research Institute of the McGill University Health Centre.

(2016-2018) Sub-Investigator for PALISADE Study (AR101 by AImmune). The Research Institute of the McGill University Health Centre.

Présentation

Sujets de recherche

Allergies.

Disciplines de recherche

Immunologie.

Mots-clés

allergie alimentaire, déficit immunitaire, immunologie clinique, immunotherapie, immunothérapie épicutanée, immunothérapie orale, Qualité de vie, tolérance soutenue.

Intérêts de recherche

Intérêt particulier pour les facteurs prédictifs de bon et mauvais pronostic d'immunothérapie ainsi que les déterminants de la tolérance soutenue. La qualité de vie des patients étant au coeur de mes travaux, je porte un intérêt aux diverses méthodes et traitements adjuvants afin d'accélérer et faciliter le processus d'immunothérapie incluant les phases de désensibilisation et de tolérance soutenue.

Recherche clinique

Oui

Centre de recherche

Centre de recherche du CHUS

Langues parlées et écrites

Anglais, Français

Prix et distinctions

  • Allergy Fellowship Award. The Association of Allergists and Immunologists of Québec. (Prix / Récompense).
  • Prix pour la meilleure présentation d'affiche scientifique. (Prix / Récompense).

Publications

Articles de revue

  • De Schryver S, Mazer B, Clarke A, St Pierre Y, Lejtneyi D, Langlois A, Torabi B, Zhao WW, Chan ES, Baerg I, Ben-Shoshan M. (2019). Adverse events in oral immunotherapy for the desensitization of cow's milk allergy in children: a randomized controlled trial. JACI: In practice, (Article sous presse).
  • Langlois A, Graham F, Bégin P. (2019). Epicutaneous peanut patch device for the treatment of peanut allergy. Expert Review of Clinical Immunology, (Révisions requises).
  • Leroux, H., Langlois, A., Paradis, L., Roches, A. D., & Bégin, P. (2019). Visual assessment does not reliably predict peanut content in chocolate covered peanut candies used for oral immunotherapy. The journal of allergy and clinical immunology. In practice, DOI. (Article sous presse).
  • Langlois A, Torabi B, Dembele M, Desjardins M, Alizadehfar R, Ben-Shohan M, De Bie I, Santanna A, McCusker C, Mazer B. (2018). Gastrointestinal Defects and Immunodeficiency Syndrome with Normal in vitro IgG Production. Lymphosign, 5, 91-99.
  • Gabrielli S, Langlois A, Ben-Shoshan M. (2018). Prevalence of hypersensitivity reactions in children associated with acetaminophen: A systematic review and a meta-analysis. International Archives of Allergy and Immunology, 176, 106-114. (Article publié).

Chapitres de livre

  • Langlois A, Ben Shoshan M. (2019). Chapter 15: Facial Angioedema Following Smoothie Ingestion. Rezaei N Pediatric Allergy and Clinical Immunology: A Case-Based Collection with Multiple Choice Questions Suisse : Springer. (Article accepté).
  • Langlois A, Alizadehfar R. (2019). Chapter 144: Lymphopenia and neutropenia. Rahmani F Volume II: Pediatric Immunology Suisse : Springer. (Article accepté).

Articles de conférence

  • Tritt A, Langlois A, Gabrielli S, Lejtenyi C, Eiwegger T,Atkinson A, Kim V, O'Keefe A, Yanishevsky Y, Ben-Shoshan M. Immediate and Delayed Reactions to Cephalexin in Children with Confirmed Allergy to Amoxicillin. CSACI Annual Conference.
  • Torabi B, Langlois A, Alizadehfar R, Ben-Shoshan M, McCusker C, Mazer B. Multiple intestinal atresia with combined immunodeficiency. CIS Annual Meeting: Immune Deficiency & Dysregulation.
  • A. Langlois, H. Leroux, L. Paradis, A. Des Roches, P. Bégin. Peanut content of chocolate coated peanut candies present a higher variability when compared to conventional peanuts. European Academy of Allergy and Clinical Immunology - Annual Meeting.
  • De Schryver S, Mazer M, Clarke A, St. Pierre Y, Leytenji D, Langlois A, Torabi B, Chan E, Ben-Shoshan M. Safety profile of the first Canadian randomized controlled trial of oral immunotherapy with cow’s milk in children. CSACI Annual Meeting.
  • Langlois A, Gabrielli S, Clarke A, De Schryver S, Shand G, Ben-­Shoshan M. Temporal Trends of Food Specific IgE Levels During and After Anaphylaxis. AAAAI/WAO Joint Meeting.

Autres contributions

Présentations

  • (2019). A 15 months, double-Blind, randomized controlled trial comparing 20 weeks of two doses of Omalizumab to placebo to accelerate a symptom-driven Oral immunotherapy schedule in subjects aged 6 to 25 years with Multiple food allergies (BOOM). Conférence Scientifique Bram Rose. Lac Beauport.
  • (2019). Peanut content of chocolate coated peanut candies present a higher variability when compared to conventional peanuts. European Academy of Allergy and Clinical Immunology - Annual Conference. Lisbonne.
  • (2018). Family matters - Synonymous variants in X-Linked Lymphoproliferative disorder. Immunodeficiency Canada - Primary Immunodeficiency Webcast. Canada.
  • (2017). SCID induced by mutations of PGM3. Bram Rose Conference - The Allergists and Immunologist of Quebec Annual Meeting. Canada.
  • (2016). Multiple Intestinal Atresia With Combined Immune Deficiency: a case report. CSACI Annual Meeting. Canada.