Publications 2014

M’Hamed Bentourkia

Positron emission tomography imaging for vascular inflammation evaluation in elderly subjects with different risk factors for cardiovascular diseases 
Khalil, A., M. R. Orellana, T. Fulop, E. E. Turcotte, et M. Bentourkia.
American journal of nuclear medicine and molecular imaging 4, no 3 (2014): 283 92.

Guylain Boulay

Functional Consequences of the over-Expression of TRPC6 Channels in HEK Cells: Impact on the Homeostasis of Zinc 
Chevallet, M., L. Jarvis, A. Harel, S. Luche, S. Degot, V. Chapuis, G. Boulay, T. Rabilloud, et A. Bouron.
Metallomics 6, no 7 (2014): 1269.

André Cantin

Interspecific small molecule interactions between clinical isolates of Pseudomonas aeruginosa and Staphylococcus aureus from adult cystic fibrosis patients 
Fugere, A., D. Lalonde Seguin, G. Mitchell, E. Deziel, V. Dekimpe, A. M. Cantin, E. Frost, et F. Malouin.
PloS one 9, no 1 (2014): e86705.

Inhibition of influenza virus replication by targeting broad host cell pathways
Marois, I., A. Cloutier, I. Meunier, H. M. Weingartl, A. M. Cantin, et M. V. Richter.
PloS one 9, no 10 (2014): e110631.

Paul Charette

Cell detachment and label-free cell sorting using modulated surface acoustic waves (SAWs) in droplet-based microfluidics 
Bussonnière, A., Y. Miron, M. Baudoin, O. Bou Matar,M. Grandbois, P. G. Charette, et A. Renaudin.
Lab on a Chip 14, no 18 (2014): 3556–3563.

CMOS BQJ detector chip with integrated charge-amplifiers for fluorescence measurements 
Courcier, T., M. Goulart, P. Pittet, D. W. de Lima Monteiro, P. G. Charette, V. Aimez, et G.-N. Lu.
Sensors and Actuators B: Chemical 190 (2014): 288–294.

BQJ Photodetector Signal Processing
Courcier, T., P. Pittet, P. G. Charette, V. Aimez, et G. N. Lu.
In Key Engineering Materials, 605:91–94. Trans Tech Publications, 2014.

Opto-electrical Modeling of CMOS Buried Quad Junction Photodetector
Feruglio, S., T. Courcier, A. Karami, A. Alexandre-Gauthier, O. Romain, V. Aimez, P. G. Charette, P. Pittet, et G.-N. Lu.
In Key Engineering Materials, 605:470–473. Trans Tech Publications, 2014.

Robert Day

PACE4-based molecular targeting of prostate cancer using an engineered (6)(4)Cu-radiolabeled peptide inhibitor 
Couture, F., C. Levesque, V. Dumulon-Perreault, S. Ait-Mohand, F. D’Anjou, R. Day, et B. Guerin.
Neoplasia (New York, N.Y.) 16, no 8 (2014): 634 43.

Knockdown strategies for the study of proprotein convertases and proliferation in prostate cancer cells 
D’Anjou, F., F. Couture, R. Desjardins, et R. Day.
Methods in molecular biology (Clifton, N.J.) 1103, no Journal Article (2014): 67 82.

Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin 
Gagnon, H., S. Beauchemin, A. Kwiatkowska, F. Couture, F. D’Anjou, C. Levesque, F. Dufour, eA. R. Desbiens, R. Vaillancourt, S. Bernard, R. Desjardins, F. Malouin, Y. L. Dory, R. Day
Journal of medicinal chemistry 57, no 1 (2014): 29 41.

Design, synthesis, and structure-activity relationship studies of a potent PACE4 inhibitor
Kwiatkowska, A., F. Couture, C. Levesque, K. Ly, R. Desjardins, S. Beauchemin, A. Prahl, B. Lammek, W. Neugebauer, Y. L. Dory et R. Day
Journal of medicinal chemistry 57, no 1 (2014): 98 109.

Implications of Proprotein Convertases in Ovarian Cancer Cell Proliferation and Tumor Progression: Insights for PACE4 as a Therapeutic Target 
Longuespee, R., F. Couture, C. Levesque, A. Kwiatkowska, R. Desjardins, S. Gagnon, D. Vergara, M. Maffia, I. Fournier, M. Salzet et R. Day
Translational oncology, no Journal Article (2014).

Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9 
Ly, K., Y. G. Saavedra, M. Canuel, S. Routhier, R. Desjardins, J. Hamelin, J. Mayne, C. Lazure, N. G. Seidah, et R. Day.
The Journal of biological chemistry 289, no 25 (2014): 17732 46.

Artur de Brum Fernandes

Cytosolic phospholipase A2 and eicosanoids modulate life, death and function of human osteoclasts in vitro
Allard-Chamard, H., P. Dufort, S. Haroun, et A. J. de Brum-Fernandes.
Prostaglandins, leukotrienes, and essential fatty acids 90, no 4 (2014): 117 23.

Secreted phospholipase A2 type II is present in Paget’s disease of bone and modulates osteoclastogenesis, apoptosis and bone resorption of human osteoclasts independently of its catalytic activity in vitro 
Allard-Chamard, H., S. Haroun, et A. J. de Brum-Fernandes.
Prostaglandins, leukotrienes, and essential fatty acids 90, no 2 3 (2014): 39 45.

Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels 
Jones, J. D., B. J. Hamilton, G. J. Challener, A. J. de Brum-Fernandes, P. Cossette, P. Liang, A. Masetto, H. A. Menard, N. Carrier, D. L. Boyle, S. Rosengren, G. Boire et W. F. Rigby
Arthritis research & therapy 16, no 2 (2014): R103.

Prostaglandin D(2) induces apoptosis of human osteoclasts through ERK1/2 and Akt signaling pathways 
Yue, L., S. Haroun, J. L. Parent, et A. J. de Brum-Fernandes.
Bone 60, no Journal Article (2014): 112 21.

Jean-Bernard Denault

General In Vitro Caspase Assay Procedures
Boucher, D., C. Duclos, et J.-B.Denault.
In Caspases,Paracaspases, and Metacaspases, édité par Peter V. Bozhkov, Guy Salvesen, et Peter V. Bozhkov,
Methods in Molecular Biology 1133. Springer New York, 2014.

Yves Dory

Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin 
Gagnon, H., S. Beauchemin, A. Kwiatkowska, F. Couture, F. D’Anjou, C. Levesque, F. Dufour, A. R. Desbiens, R. Vaillancourt, S. Bernard, R. Desjardins, F. Malouin, Y. L. Dory, R. Day
Journal of medicinal chemistry 57, no 1 (2014): 29 41.

Design, synthesis, and structure-activity relationship studies of a potent PACE4 inhibitor
Kwiatkowska, A., F. Couture, C. Levesque, K. Ly, R. Desjardins, S. Beauchemin, A. Prahl, B. Lammek, W. Neugebauer, Y. L. Dory et R. Day
Journal of medicinal chemistry 57, no 1 (2014): 98 109.

Emanuel Escher

Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor 
Sainsily, X., J. Cabana, B. J. Holleran, E. Escher, P. Lavigne, et R. Leduc.
Biochemical pharmacology 92, no 2 (2014): 280 88.

David Fortin

Impact of drug size on brain tumor and brain parenchyma delivery after a blood-brain barrier disruption 
Blanchette, M., L. Tremblay, M. Lepage, et D. Fortin.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 34, no 5 (2014): 820 26.

Real-time multi-peak tractography for instantaneous connectivity display
Chamberland, M., K. Whittingstall, D. Fortin, D. Mathieu, et M. Descoteaux.
Frontiers in neuroinformatics 8, no Journal Article (2014): 59.

Intra-arterial carboplatin as a salvage strategy in the treatment of recurrent glioblastoma multiforme 
Fortin, D., P. A. Morin, F. Belzile, D. Mathieu, et F. M. Pare.
Journal of neuro-oncology 119, no 2 (2014): 397 403.
doi:10.1007/s11060-014-1504-4.

A new der(1;7)(q10;p10) leading to a singular 1p loss in a case of glioblastoma with oligodendroglioma component
Gadji, M., A. M. Crous-Tsanaclis, D. Mathieu, S. Mai, D. Fortin, et R. Drouin.
Neuropathology : official journal of the Japanese Society of Neuropathology 34, no 2 (2014): 170 78.

Structural network underlying visuospatial imagery in humans
Whittingstall, K., M. Bernier, J. C. Houde, D. Fortin, et M. Descoteaux.
Cortex; a journal devoted to the study of the nervous system and behavior 56, no Journal Article (2014): 85 98.

Luc Gaudreau

Defining molecular sensors to assess long-term effects of pesticides on carcinogenesis
L’Heritier, F., M. Marques, M. Fauteux, et L. Gaudreau.
International journal of molecular sciences 15, no 9 (2014): 17148 61.

Low levels of 3,3’-diindolylmethane activate estrogen receptor alpha and induce proliferation of breast cancer cells in the absence of estradiol 
Marques, M., L. Laflamme, I. Benassou, C. Cissokho, B. Guillemette, et L. Gaudreau.
BMC cancer 14, no Journal Article (2014): 524-2407-14 524.

Louis Gendron

Label-free monitoring of mu-opioid receptor-mediated signaling
Bourassa, P., H. B. Tudashki, G. Pineyro, M. Grandbois, et L. Gendron.
Molecular pharmacology 86, no 2 (2014): 138 49.

Involvement of cannabinoid receptors in peripheral and spinal morphine analgesia
Desroches, J., J.-F. Bouchard, L. Gendron, et P. Beaulieu.
Neuroscience 261 (2014): 23–42.

Identification of 1-(${$[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1 H-pyrazol-3-yl] carbonyl$}$ amino) cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compound
Thomas, J. B., A. M. Giddings, R. W. Wiethe, S.Olepu, K. R. Warner, P. Sarret, L. Gendron, J.-M. Longpre, Y. Zhang, Scott P. Runyon, B.P. Gilmour
Journal of medicinal chemistry 57, no 12 (2014): 5318–5332.

Identification of N-[(5-${$[(4-Methylphenyl) sulfonyl] amino$}$-3-(trifluoroacetyl)-1 H-indol-1-yl) acetyl]-l-leucine (NTRC-824), a Neurotensin-like Nonpeptide Compound Selective for the Neurotensin Receptor Type 2
Thomas, J. B., A. M. Giddings, R. W. Wiethe, S.Olepu, K. R. Warner, P. Sarret, L. Gendron, J.-M. Longpre, Y. Zhang, Scott P. Runyon, B.P. Gilmour
Journal of medicinal chemistry 57, no 17 (2014): 7472–7477.

Fernand Gobeil

Preclinical Pharmacology, Metabolic Stability, Pharmacokinetics and Toxicology of the Peptidic Kinin B1 Receptor Antagonist R-954
Gobeil, F. Jr, P. Sirois, et D. Regoli.
Peptides 52 (2014): 82 89.

Subcellular Localization of Coagulation Factor II Receptor-like 1 in Neurons Governs Angiogenesis 
Joyal, J.-S., S. Nim, T. Zhu, N. Sitaras, J.C. Rivera, Z. Shao, P. Sapieha, D. Hamel, M. Sanchez, K. Zaniolo, M. St-Louis, J. Ouellette, M. Montoya-Zavala, A. Zabeida, E. Picard, P. Hardy, V. Bhosle, D. R. Varma, F. Jr. Gobeil, C. Beauséjour, C. Boileau, W. Klein, M. Hollenberg, A. Ribeiro-da-Silva, G.Andelfinger et S. Chemtob
Nature Medicine 20, no 10 (2014): 1165 73.

Michel Grandbois

Amplification of AngII-dependent cell contraction by glyoxal: implication of cell mechanical properties and actomyosin activity
Boucher, J., E. Simard, U. Froehlich, et M. Grandbois.
Integrative biology : quantitative biosciences from nano to macro 6, no 4 (2014): 411 21.

Label-free monitoring of mu-opioid receptor-mediated signaling
Bourassa, P., H. B. Tudashki, G. Pineyro, M. Grandbois, et L. Gendron.
Molecular pharmacology 86, no 2 (2014): 138 49.

Cell detachment and label-free cell sorting using modulated surface acoustic waves (SAWs) in droplet-based microfluidics 
Bussonnière, A., Y. Miron, M. Baudoin, O. Bou Matar,M. Grandbois, P. G. Charette, et A. Renaudin.
Lab on a Chip 14, no 18 (2014): 3556–3563.

Brigitte Guérin

Development of bifunctional chelates bearing hydroxamate arms for highly efficient (64)Cu radiolabeling
Ait-Mohand, S., C. Denis, G. Tremblay, M. Paquette, et B. Guerin.
Organic letters 16, no 17 (2014): 4512 15.

Increased brown adipose tissue oxidative capacity in cold-acclimated humans
Blondin, D. P., S. M. Labbe, H. C. Tingelstad, C. Noll, M. Kunach, S. Phoenix, B. Guerin, E. E. Turcotte, A. C. Carpentier, D. Richard et F. Haman
The Journal of clinical endocrinology and metabolism 99, no 3 (2014): E438-46.

PACE4-based molecular targeting of prostate cancer using an engineered (6)(4)Cu-radiolabeled peptide inhibitor 
Couture, F., C. Levesque, V. Dumulon-Perreault, S. Ait-Mohand, F. D’Anjou, R. Day, et B. Guerin.
Neoplasia (New York, N.Y.) 16, no 8 (2014): 634 43.

Improved cardiac function and dietary fatty acid metabolism after modest weight loss in subjects with impaired glucose tolerance
Labbe, S. M., C. Noll, T. Grenier-Larouche, M. Kunach, L. Bouffard, S. Phoenix,B. Guerin, J. P. Baillargeon, M. F. Langlois, E. E. Turcotte et A. C. Carpentier
American journal of physiology.Endocrinology and metabolism 306, no 12 (2014): E1388-96.

Gaetan Guillemette

STIM1 positively regulates the Ca2+ release activity of the inositol 1,4,5-trisphosphate receptor in bovine aortic endothelial cells
Beliveau, E., V. Lessard, et G. Guillemette. .
PloS one 9, no 12 (2014): e114718.

Daniel Lafontaine

RNA conformational changes analyzed by comparative gel electrophoresis
Eschbach, S. H., et D. A. Lafontaine.
Methods in molecular biology (Clifton, N.J.) 1086, no Journal Article (2014): 255 64.

Using sm-FRET and denaturants to reveal folding landscapes
Shaw, E., P. St-Pierre, K. McCluskey, D. A. Lafontaine, et J. C. Penedo.
Methods in enzymology 549, no Journal Article (2014): 313 41.

Pierre Lavigne

Abeta induces its own prion protein N-terminal fragment (PrPN1)-mediated neutralization in amorphous aggregates
Beland, M., M. Bedard, G. Tremblay, P. Lavigne, et X. Roucou.
Neurobiology of aging 35, no 7 (2014): 1537 48.

Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor 
Sainsily, X., J. Cabana, B. J. Holleran, E. Escher, P. Lavigne, et R. Leduc.
Biochemical pharmacology 92, no 2 (2014): 280 88.

Christine Lavoie

Galphas regulates the post-endocytic sorting of G protein-coupled receptors
Rosciglione, S., C. Theriault, M. O. Boily, M. Paquette, et C. Lavoie.
Nature communications 5, no Journal Article (2014): 4556.

Roger Lecomte

Comment on “Temperature dependence of APD-based PET scanners
Cadorette, J., M. Bergeron, C. Thibaudeau, J. F. Beaudoin, C. M. Pepin, et R. Lecomte.
Medical physics 41, no 1 (2014): 17101.

Deciphering PDT-induced inflammatory responses using real-time FDG-PET in a mouse tumour model
Cauchon, N., H. M. Hassessian, E. Turcotte, R. Lecomte, et J. E. van Lier.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 13, no 10 (2014): 1434 43.

Automatic Channel Fault Detection and Diagnosis System for a Small Animal APD-Based Digital PET Scanner
Charest, J., J.-F. Beaudoin, J. Cadorette, R. Lecomte, C.-A. Brunet, et R. Fontaine.
IEEE Transactions on Nuclear Science 61, no 5 (octobre 2014): 2494 2502.

Arterial input function sampling without surgery in rats for positron emission tomography molecular imaging
Croteau, E., E. Poulin, S. Tremblay, V. Dumulon-Perreault, O. Sarrhini, M. Lepage, et R. Lecomte.
Nuclear medicine communications 35, no 6 (2014): 666 76.

(11)C]-Acetoacetate PET imaging: a potential early marker for cardiac heart failure
Croteau, E., S. Tremblay, S. Gascon, V. Dumulon-Perreault, S. M. Labbe, J. A. Rousseau, S. C. Cunnane, A. C. Carpentier, F. Benard, et R. Lecomte.
Nuclear medicine and biology 41, no 10 (2014): 863 70.

A Longitudinal Low Dose μCT Analysis of Bone Healing in Mice: A Pilot Study
Di, Lu-Zhao, V. Couture, E. Leblanc, Y. Alinejad, J.-F. Beaudoin, R. Lecomte, F. Berthod, N. Faucheux, F. Balg, et G. Grenier.
Advances in Orthopedics 2014 (2014): 791539.

Richard Leduc

Cleavage Specificity Analysis of Six Type II Transmembrane Serine Proteases (TTSPs) Using PICS with Proteome-Derived Peptide Libraries
Barré, O., A. Dufour, U. Eckhard, R. Kappelhoff, F. Béliveau, R. Leduc, et C. M. Overall.
PLOS ONE 9, no 9 (11 septembre 2014): e105984. doi:10.1371/journal.pone.0105984.

Biased signaling regulates the pleiotropic effects of the urotensin II receptor to modulate its cellular behaviors
Brule, C., N. Perzo, J. E. Joubert, X. Sainsily, R. Leduc, H. Castel, et L. Prezeau.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, no 12 (2014): 5148 62. doi:10.1096/fj.14-249771.

Conjugation of a Brain-Penetrant Peptide with Neurotensin Provides Antinociceptive Properties
Demeule, M., N. Beaudet, A. Régina, É. Besserer-Offroy, A. Murza, P. Tétreault, K. Belleville, C. Ché, A. Larocque, C. Thiot, R. Béliveau, J.-M. Longpré, É. Marsault, R. Leduc, J.E. Lachowicz, S. L. Gonias, J.-P. C. et P. Sarret
The Journal of Clinical Investigation 124, no 3 (2014): 1199 1213. doi:10.1172/JCI70647.

Analysis of subpocket selectivity and identification of potent selective inhibitors for matriptase and matriptase-2
Duchene, D., E. Colombo, A. Desilets, P. L. Boudreault, R. Leduc, E. Marsault, et R. Najmanovich.
Journal of medicinal chemistry 57, no 23 (2014): 10198 204. doi:10.1021/jm5015633.

Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor 
Sainsily, X., J. Cabana, B. J. Holleran, E. Escher, P. Lavigne, et R. Leduc.
Biochemical pharmacology 92, no 2 (2014): 280 88.

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis
Tang, X., S.S. Mahajan, L. T. Nguyen, F. Béliveau, R. Leduc, J. A. Simon et V. Vasioukhin,
Oncotarget 5, no 5 (2014): 1352 62.

Claude Legault

Synthesis and characterization of combined cross-linked laccase and tyrosinase aggregates transforming acetaminophen as a model phenolic compound in wastewaters
Ba, S., L. Haroune, C. Cruz-Morato, C. Jacquet, I. E. Touahar, J. P. Bellenger, C. Y. Legault, J. P. Jones, et H. Cabana.
The Science of the total environment 487, no Journal Article (2014): 748 55.

Photocatalytic degradation of carbamazepine and three derivatives using TiO(2) and ZnO: effect of pH, ionic strength, and natural organic matter
Haroune, L., M. Salaun, A. Menard, C. Y. Legault, et J. P. Bellenger. 
The Science of the total environment 475, no Journal Article (2014): 16 22.

Diazirines as potent electrophilic nitrogen sources: application to the synthesis of pyrazoles
Schneider, Y., J. Prevost, M. Gobin, et C. Y. Legault.
Organic letters 16, no 2 (2014): 596 99.

Synthesis of Pyrazoles with Diazirines as Electrophilic Nitrogen Sources
Schneider, Y., J. Prévost, M. Gobin, et C. Y. Legault.
Synfacts 10, no 4 (2014): 418–418.

Martin Lepage

Impact of drug size on brain tumor and brain parenchyma delivery after a blood-brain barrier disruption 
Blanchette, M., L. Tremblay, M. Lepage, et D. Fortin.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 34, no 5 (2014): 820 26.

Arterial input function sampling without surgery in rats for positron emission tomography molecular imaging
Croteau, E., E. Poulin, S. Tremblay, V. Dumulon-Perreault, O. Sarrhini, M. Lepage, et R. Lecomte.
Nuclear medicine communications 35, no 6 (2014): 666 76.

A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging
Lebel, R., et M. Lepage.
Contrast media & molecular imaging 9, no 3 (2014): 187 210.

Glucose hypometabolism is highly localized, but lower cortical thickness and brain atrophy are widespread in cognitively normal older adults
Nugent, S., C. A. Castellano, P. Goffaux, K. Whittingstall, M. Lepage, N. Paquet, C. Bocti, T. Fulop, et S. C. Cunnane.
American journal of physiology.Endocrinology and metabolism 306, no 11 (2014): E1315-21.

Brain glucose and acetoacetate metabolism: a comparison of young and older adults
Nugent, S., S. Tremblay, K. W. Chen, N. Ayutyanont, A. Roontiva, C. A. Castellano, M. Fortier, M. Roy, A. Courchesne-Loyer, C. Bocti, M. Lepage, E. Turcotte, T. Fulop, E. M. Reiman, S. C. Cunnane
Neurobiology of aging 35, no 6 (2014): 1386 95.

Éric Marsault

Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus
Chagnon, F., I. Guay, M. A. Bonin, G. Mitchell, K. Bouarab, F. Malouin, et E. Marsault.
European journal of medicinal chemistry 80, no Journal Article (2014): 605 20. doi:10.1016/j.ejmech.2013.11.019.

Conjugation of a Brain-Penetrant Peptide with Neurotensin Provides Antinociceptive Properties
Demeule, M., N. Beaudet, A. Régina, É. Besserer-Offroy, A. Murza, P. Tétreault, K. Belleville, C. Ché, A. Larocque, C. Thiot, R. Béliveau, J.-M. Longpré, É. Marsault, R. Leduc, J.E. Lachowicz, S. L. Gonias, J.-P. C. et P. Sarret
The Journal of Clinical Investigation 124, no 3 (2014): 1199 1213.

Analysis of subpocket selectivity and identification of potent selective inhibitors for matriptase and matriptase-2
Duchene, D., E. Colombo, A. Desilets, P. L. Boudreault, R. Leduc, E. Marsault, et R. Najmanovich.
Journal of medicinal chemistry 57, no 23 (2014): 10198 204.

Stability and degradation patterns of chemically modified analogs of apelin-13 in plasma and cerebrospinal fluid
Murza, A., K. Belleville, J. M. Longpre, P. Sarret, et E. Marsault.
Biopolymers 102, no 4 (2014): 297 303.

Solid-phase synthesis of piperazinones via disrupted Ugi condensation
Treder, A. P., M. C. Tremblay, A. K. Yudin, et E. Marsault.
Organic letters 16, no 17 (2014): 4674 77.

One-pot synthesis of polyunsaturated fatty acid amides with anti-proliferative properties
Tremblay, H., C. St-Georges, M. A. Legault, C. Morin, S. Fortin, et E. Marsault.
Bioorganic & medicinal chemistry letters 24, no 24 (2014): 5635 38.

Rafael Najmanovich

Analysis of subpocket selectivity and identification of potent selective inhibitors for matriptase and matriptase-2
Duchene, D., E. Colombo, A. Desilets, P. L. Boudreault, R. Leduc, E. Marsault, et R. Najmanovich.
Journal of medicinal chemistry 57, no 23 (2014): 10198 204. 

A coarse-grained elastic network atom contact model and its use in the simulation of protein dynamics and the prediction of the effect of mutations
Frappier, V., et R. J. Najmanovich.
PLoS computational biology 10, no 4 (2014): e1003569.

Deep-sequencing of the peach latent mosaic viroid reveals new aspects of population heterogeneity
Glouzon, J. P., F. Bolduc, S. Wang, R. J. Najmanovich, et J. P. Perreault.
PloS one 9, no 1 (2014): e87297.

A curated C. difficile strain 630 metabolic network: prediction of essential targets and inhibitors
Larocque, M., T. Chenard, et R. Najmanovich.
BMC systems biology 8, no Journal Article (2014): 117 014 0117 z.

Jean-Luc Parent

A G protein-coupled receptor and the intracellular synthase of its agonist functionally cooperate
Binda, C., S. Genier, A. Cartier, J. F. Larrivee, J. Stankova, J. C. Young, et J. L. Parent.
The Journal of cell biology 204, no 3 (2014): 377 93.

New insights in the regulation of Rab GTPases by G protein-coupled receptors
Lachance, V., S. Angers, et J.-L. Parent.
Small GTPases 5, no 4 (2014): e983872.

Ubiquitylation and Activation of a Rab GTPase Is Promoted by a β2AR–HACE1 Complex
Lachance, V., J. Degrandmaison, S. Marois, M. Robitaille, S. Génier, S. Nadeau, S. Angers, et J.-L. Parent.
J Cell Sci 127, no 1 (2014): 111 23.

Prostaglandin D(2) induces apoptosis of human osteoclasts through ERK1/2 and Akt signaling pathways 
Yue, L., S. Haroun, J. L. Parent, et A. J. de Brum-Fernandes.
Bone 60, no Journal Article (2014): 112 21.

Marek Rola Pleszczynski

Rapid evaluation of the absence of inflammation after rupture of membranes
Berthiaume, M., É. Rousseau,M. Rola-Pleszczynski, et J.-C. Pasquier.
The Journal of Maternal-Fetal & Neonatal Medicine 27, no 9 (2014): 865 69.

Interleukin-15 in the Regulation of Obesity and Fatty Liver Disease
Ramanathan, S., G. Lacraz, Y. C. Donates, M. Mayhue, M. F. Langois, M. Rola Pleszczynski, et S. Ilangumaran.
Journal of Clinical and Experimental Hepatology 4 (2014): S32.

Philippe Sarret

Improving the Selection of True Incident Cases of Low Back Pain by Screening Retrospective Administrative Data
Beaudet, N., J. Courteau,P. Sarret, et A. Vanasse.
European Journal of Pain (London, England) 18, no 7 (2014): 923 31.

Functional up-regulation of Nav1.8 sodium channel in Abeta afferent fibers subjected to chronic peripheral inflammation
Belkouch, M., M. A. Dansereau, P. Tetreault, M. Biet, N. Beaudet, R. Dumaine, A. Chraibi, S. Melik-Parsadaniantz, et P. Sarret.
Journal of neuroinflammation 11, no Journal Article (2014): 45-2094-11 45.

Conjugation of a Brain-Penetrant Peptide with Neurotensin Provides Antinociceptive Properties
Demeule, M., N. Beaudet, A. Régina, É. Besserer-Offroy, A. Murza, P. Tétreault, K. Belleville, C. Ché, A. Larocque, C. Thiot, R. Béliveau, J.-M. Longpré, É. Marsault, R. Leduc, J.E. Lachowicz, S. L. Gonias, J.-P. C. et P. Sarret
The Journal of Clinical Investigation 124, no 3 (2014): 1199 1213.

Implication of the ERK/MAPK pathway in antipsychotics-induced dopamine D2 receptor upregulation and in the preventive effects of (+/-)-alpha-lipoic acid in SH-SY5Y neuroblastoma cells
Deslauriers, J., C. Desmarais, P. Sarret, et S. Grignon.
Journal of molecular neuroscience : MN 52, no 3 (2014): 378 83.

Preventive effect of α-lipoic acid on prepulse inhibition deficits in a juvenile two-hit model of schizophrenia
Deslauriers, J., W. Racine, P. Sarret, et S. Grignon.
Neuroscience 272 (11 juillet 2014): 261 70.

Stability and degradation patterns of chemically modified analogs of apelin-13 in plasma and cerebrospinal fluid
Murza, A., K. Belleville, J. M. Longpre, P. Sarret, et E. Marsault.
Biopolymers 102, no 4 (2014): 297 303.

Identification of 1-(${$[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1 H-pyrazol-3-yl] carbonyl$}$ amino) cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compound
Thomas, J. B., A. M. Giddings, R. W. Wiethe, S.Olepu, K. R. Warner, P. Sarret, L. Gendron, J.-M. Longpre, Y. Zhang, Scott P. Runyon, B.P. Gilmour
Journal of medicinal chemistry 57, no 12 (2014): 5318–5332.

Identification of N-[(5-${$[(4-Methylphenyl) sulfonyl] amino$}$-3-(trifluoroacetyl)-1 H-indol-1-yl) acetyl]-l-leucine (NTRC-824), a Neurotensin-like Nonpeptide Compound Selective for the Neurotensin Receptor Type 2
Thomas, J. B., A. M. Giddings, R. W. Wiethe, S.Olepu, K. R. Warner, P. Sarret, L. Gendron, J.-M. Longpre, Y. Zhang, Scott P. Runyon, B.P. Gilmour
Journal of medicinal chemistry 57, no 17 (2014): 7472–7477.

Claude Spino

Modern Methods in Stereoselective Aldol Reactions
Spino, C.
Edited by Rainer Mahrwald. Wiley Online Library, 2014. 

Jana Stankova

A G protein-coupled receptor and the intracellular synthase of its agonist functionally cooperate
Binda, C., S. Genier, A. Cartier, J. F. Larrivee, J. Stankova, J. C. Young, et J. L. Parent.
The Journal of cell biology 204, no 3 (2014): 377 93.

Yue Zhao

Photodegradable and size-tunable single-chain nanoparticles prepared from a single main-chain coumarin-containing polymer precursor
Fan, W., X. Tong, Q. Yan, S. Fu, et Y. Zhao.
Chemical communications (Cambridge, England) 50, no 88 (2014): 13492 94.

Dual-stimuli-responsive micelle of an ABC triblock copolymer bearing a redox-cleavable unit and a photocleavable unit at two block junctions
Xuan, J., D. Han, H. Xia, et Y. Zhao.
Langmuir : the ACS journal of surfaces and colloids 30, no 1 (2014): 410 17.

Block copolymer self-assembly controlled by the “green” gas stimulus of carbon dioxide
Yan, Q., et Y. Zhao.
Chemical communications (Cambridge, England) 50, no 79 (2014): 11631 41.

Diverse thermoresponsive behaviors of uncharged UCST block copolymer micelles in physiological medium
Zhang, H., X. Tong, et Y. Zhao.
Langmuir : the ACS journal of surfaces and colloids 30, no 38 (2014): 11433 41.