- Type :
- Conférences et séminaires
- Lieu :
Dîner-conférence du Pr. Patrick Gunning (Department of Chemical & Physical Sciences, University of Toronto)
Most biological processes involve permanent and non-permanent interactions between different proteins. Many protein complexation events play key roles in various human diseases. The thrust of professor Gunning research focuses on the development of novel, small molecule architectures to reverse an aberrant role of proteins. He will describe the challenges they faced in developing new drug molecules to fight the most rare and lethal of human cancers as glioblastoma (brain cancer) and acute myeloid leukemia (blood cancer). With a wide range of research disciplines including organic synthesis, biophysics, computational chemistry, medicinal chemistry and molecular biology, professor Gunning breaks down the drug development process leading to drugs for clinical trials.