In 2013, the Pharmacology Institute of Sherbrooke (IPS) launched a project to centralize the molecules synthesized by its member chemists. This initiative has enabled the development of a unique collection of compounds of great structural diversity. An increase in chemical space is necessary to successfully identify molecules effective on the new therapeutic targets. The compounds in the IPS Chemical Library are very distinct from those found in commercial libraries and most are structurally complex.
The compounds are stored and listed in a format compatible with the various high throughput screening platforms (HTS). To date, nearly 1000 unique molecules make up the IPS Chemical Library. This collection is shared with several screening centres including the Institute for Research in Immunology and Cancer (IRIC) and the Centre for Drug Research and Development (CDRD) for testing on various biological targets, and several specimens are available for new academic or industrial screening programs.
This initiative is open to any chemist wishing to explore the therapeutic potential of their molecules. In addition, the distribution of the IPS Chemical Library can also serve as a starting point for enriching interdisciplinary collaborations between chemists and biologists. If you are interested in enriching the collection of the IPS Chemical Library or if you would like a specimen from it, contact Prof. Éric Marsault, the person in charge of the library.
Instructions for preparing compounds.
Brochure IPS Chemical Library