PRATTE Jean-François

Jr. Eng., Ph. D.
Associate professor




  • B. Ing., Electrical Engineering, Université de Sherbrooke, 1999
  • M.A.Sc., Electrical Engineering, Université de Sherbrooke, 2002
  • Ph.D., Electrical Engineering, Université de Sherbrooke, 2008

Research expertise and domains

  • Integrated circuits and electronics for radiation instrumentation and imaging systems.
  • Low noise analog circuits.
  • 3D packaging of integrated circuits.

Research Activities

Medical imaging systems:

  • Dual modality Positron Emission Tomography (PET) with time of flight capability / Computed Tomography (CT)
  • Low dose Computed Tomography (CT).
  • Full body small animal PET/CT readout integrated circuit (LabPET II)
  • The RatCAP (Rat Conscious Animal PET): head mounted miniature and portable PET scanner for brain metabolism studies (Brookhaven National Lab, Upton, NY).
  • RatCAP-based dual modality PET and Magnetic Resonance Imaging (MRI) for small animal and breast cancer studies (Brookhaven National Lab, Upton, NY).
  • CZT-based PET scanner for mice brain imaging (Brookhaven National Lab, Upton, NY).

Photon science:

  • Front-end electronics for X-rays active matrix pixel sensor for the X-rays pump and probe instrument at the LINAC Coherent Light Source (SLAC National Accelerator Laboratory, Stanford, CA).

Teaching Activities

S8 - GEI710 – Design of integrated circuits -

Scientific communications

  • Corbeil Therrien, A.; Bérubé, B.-L.; Thibaudeau, C.; Charlebois, S.; Lecomte, R.; Fontaine, R.; Pratte, J.-F. Modeling of Single Photon Avanlanche Diode Array Detector for PET Applications : Part I, to be submitted to the IEEE Trans. Nucl. Sci. during fall 2012.
  • Convert, L.; Girard Baril, F.; Boisselle, V.;  Pratte, J.-F.; Fontaine, R.; Lecomte, R.;  Charette, P.G.; Aimez, V. Blood compatible microfluidic system for pharmacokinetic studies in small animals, Lab on a Chip, DOI: 10.1039/C2LC40550D, published online 23/08/2012, 2012.
  • Maramraju, S. H.; Smith, S. D.; Junnarkar, S.S.; Schulz, D.; Stoll, S.; Ravindranath, B.; Purschke, M.L.; Rescia, S.; Southekal, S.; Pratte, J.-F.; Vaska, P.; Woody, C.L.; Schlyer, D.J. Small animal simultaneous PET/MRI: Initial experiences in a 9.4 T microMRI, Phys. Med. Biol., vol. 56, pp. 2459-2480, 03/25, 2011.
  • Schulz, D.; Southekal, S.; Junnarkar, S.S.; Pratte, J.-F.; Purschke, M.L.; Stoll, S.; Ravindranath, B.; Maramraju, S.H.; Krishnamoorthy, S.; Henn, F.A.; O'Connor, P.; Woody, C.L.; Schlyer, D.J.; Vaska, P. Simultaneous assessment of rodent behavior and neurochemistry using a miniature positron emission tomograph, Nat. Methods, vol. 8, pp. 347-352, 03/13, 2011.
  • Carini, G. A.;  Chen, W.;  Dragone, A.; Fried, J.;  Jakoncic, J.; Kuczweski, A.; Li, Z.; Mead, J.;  Michta; R.;  Pratte, J.-F.;  Rehak, P.; Siddon, D.P.; Tests of small X-ray Active Matrix Pixel Sensor prototypes at the National Synchrotron Light Source, J. of Instrumentation, Vol. 4, iss. 3, [art. No. P03014], Mar. 2009.
  • Pratte, J.-F.; Junnarkar, S.; Deptuch, G.; Fried, J.; O'Connor, P.; Radeka, V.; Vaska, P.; Woody, C.; Schlyer, D.; Stoll, S.; Maramraju, S.H.; Krishnamoorthy, S.; Lecomte, R.; Fontaine, R. The RatCAP Front-End ASIC, IEEE Trans. Nucl. Sci., Vol. 55, No. 5, p. 2727-2735, Oct. 2008.  
  • Solis, E.; Tomasi, D.; Junnarkar, S.; Schlyer, D.; Vaska, P.; Woody, C.; Pratte, J-F.; O'Connor, P.; Rodriguez, A. O. Shielded transceiver RF coil array for simultaneous PET-MRI, Braz. J. of Phys., Vol. 38, No. 2, p. 287-291, June 2008.
  • Park, S.-J.; Southekal, S.; Purschke, M.; Junnarkar, S.; Pratte, J.-F.; Stoll, S.P.; Woody, C.L.; Schlyer, D.J.; Vaska, P.; Digital coincidence processing for the RatCAP conscious rat brain PET scanner, IEEE Trans. Nucl. Sci., Vol. 55, No. 1, p. 510-515, Feb 2008.
  • Junnarkar, S.; Fried, J.; Southekal, S.; Pratte, J.-F.; O'Connor, P.; Radeka, V.; Vaska, P.; Purschke, M.; Tomasi, D.; Woody, C.; Fontaine, R. Next generation of real time data acquisition, calibration and control system for the RatCAP scanner, IEEE Trans. Nucl. Sci., Vol. 55, No. 1, p. 220-224, Feb 2008.
  • Woody, C.; Schlyer, D.; Vaska, P.; Tomasi, D.; Solis-Najera, S.; Rooney, W.; Pratte, J.-F.; Junnarkar, S.; Stoll, S.; Master, Z.; Purschke, M.; Park, S.-J.; Southekal, S.; O’Connor, P.; Radeka, V. Preliminary Studies of a Simultaneous PET/MRI Scanner Based on the RatCAP Small Animal Tomograph, NIM A, Vol. 571, p. 102-105, Feb 2007.
  • Woody, C.; Vaska, P.; Schlyer, D.; Pratte, J.-F.; Junnarkar, S.; Park, S.-J.; Stoll, S.; Purschke, M.; Southekal, S.; Lee, D.; Schiffer, W.; Dewey, S.; Neill, J.; Kandasamy, A.; O’Connor, P.; Radeka, V.; Fontaine, R.; Lecomte, R. Initial Studies Using the RatCAP Conscious Animal PET Tomograph, Nucl Instrum Methods Phys Res Sect A, Vol. 571, p. 14-17, Feb 2007.
  • Fontaine, R.; Bélanger, F.; Cadorette, J.; Leroux, J.-D.; Martin, J.-P.; Michaud, J.-B.; Pratte, J.-F.; Robert, S.; Lecomte, R. Architecture of a Dual-Modality, High-Resolution, Fully Digital Positron Emission Tomography / Computed Tomography (PET/CT) Scanner for Small Animal Imaging, IEEE Trans. Nucl. Sci., Vol. 52, No. 3, p. 691-696, June 2005.
  • Vaska, P.; Woody, C. L.; Schlyer, D. J.; Shokouhi, S.; Stoll, S. P.; Pratte, J.-F.; O’Connor, P.; S. Junnarkar, S.; Rescia, S.; Yu, B.; Purschke, M.; Kandasamy, A.; Villanueva, A.; Kriplani, A.; Radeka, V.; Volkow, N.; Lecomte, R.; Fontaine, R. RatCAP: Miniaturized Head-Mounted PET for Conscious Rodent Brain Imaging, IEEE Trans. Nucl. Sci., Vol. 51, No. 5, p. 2718-2722, Oct 2004.
  • Pratte, J.-F.; Robert, S.; De Geronimo, G.; O’Connor, P.; Stoll, S.; Pepin, C. M.; Fontaine, R.; Lecomte, R. Design and Performance of 0.18-µm CMOS Charge Preamplifiers for APD-Based PET Scanners, IEEE Trans. Nucl. Sci., Vol. 51, No. 5, p. 1979-1985, Oct 2004.
  • Pratte, J.-F.; De Geronimo, G.; Junnarkar, S.; O’Connor, P.; Yu, B.; Robert, S.; Radeka, V.; Woody, C.; Stoll S.; Vaska, P.; Lecomte, R.; Fontaine, R.; Front-end electronics for the RatCAP mobile animal PET scanner, IEEE Trans. Nucl. Sci., Vol. 51, No. 4, p. 1318-1323, Aug 2004.
  • Woody, C.; Kriplani, A.; O’Connor, P.; Pratte, J.-F.; Radeka, V.; Rescia, S.; Schlyer, D.; Shokouhi, S.; Stoll, S.; Vaska, P.; Villaneuva, A.; Volkow, N.; Yu, B. RatCAP: a small, head-mounted PET tomograph for imaging the brain of an awake rat, NIM A, Vol. 527, p. 166-170, July 2004.
  • Shokouhi, S.; Stoll, S. P.; Villanueva, A.; Vaska, P.; Schlyer, D. J.; Woody, C. L.; Yu, B.; O'Connor, P.; Pratte, J.-F.; Radeka, V.; Volkow, N.; Fowler, J. S. A Noninvasive LSO-APD Blood Radioactivity Monitor for PET Imaging Studies. IEEE Trans. Nucl. Sci., Vol. 50, No. 5, p. 1457-1461, 2003
  • Pratte, J.-F.; Pepin, C. M.; Rouleau, D.; Menard, O.; Mouine, J.; Lecomte, R. Design of a fast-shaping amplifier for PET/CT APD detectors with depth-of-interaction, IEEE Trans. Nucl. Sci., Vol. 49, No. 5(2), p. 2448 – 2454, Oct 2002.
  • Lecomte, R.; Pepin, C.M.; Lepage, M. D.; Pratte, J.-F.; Dautet, H.; Binkley, D. M. Performance analysis of phoswich/APD detectors and low-noise CMOS preamplifiers for high-resolution PET systems, IEEE Trans. Nucl. Sci., Vol. 48, No. 3(2), p. 650 – 655, June 2001.