At Domus, more than 20 researchers collaborate in interdisciplinary projects. Their expertise covers both technology (computer science, engineering and geomatics) and health sciences and clinic (gerontology, occupational therapy, psychology, and neuropsychology), as well as ergonomics and design.

Over time, Domus has collaborated with national and international research centers (IATSL (Toronto), Telecom Bretagne (France), CRS4 (Italy), I2Star (Singapore) etc.), private corporations (Ericsson Canada, Rogers, Orange (France) etc.), as well as with health related organizations and housing units (Centre of Rehabilitation – Estrie, Résidence de l'Estrie, etc.).