Pr Marco Sirois, M.D.
Professeur adjoint
Membre de l'axe de recherche du CRC Étienne-LeBel du CHUS "Cancer : biologie, pronostic et diagnostic"

Service de chirurgie thoracique
Département de chirurgie
Faculté de médecine et des sciences de la santé
Université de Sherbrooke
3001, 12e Avenue Nord
Sherbrooke (Québec) J1H 5N4

Téléphone : 819 821-8000, poste 70266
Télécopieur : 819 820-6411
Études médicales

Doctorat en médecine, Université Laval, 1992-1996

Études médicales postdoctorales
  • Résidence en chirurgie générale, Université Laval et Montréal, 1996-2002
  • Fellowship en trauma, Vancouver General Hospital, BC, 2002-2003
  • Résidence en chirurgie cardiothoracique, Albert Einsten College of Medicine, NY, 2003-2005

Projets de recherche subventionnés

Analyse des propriétés pharmaco-mécaniques et physiopathologiques d'un modèle de bronches humaines mises en culture organoïde : rôle des eicosanoïdes. (BroncHUS).
Dr Marco Sirois, collaborateur
Dr Eric Rousseau, chercheur principal

Organisme subventionnaire : IRSC et Réseau en santé respiratoire du FRSQ

Initiative du chercheur

  1. Étude rétrospective en chirurgie thoracique : "Comparaison entre la pratique de deux incisions vs trois incisions par VATS (video-assisted thoracoscopy surgery) lors du traitement d'un pneumothorax spontané primaire".
    Dr Marco Sirois et Jimmy Bejjani (étudiant en médecine).

Publications

Consultez les articles scientifiques du Pr Sirois via le site PubMed.

Occult pneumothoraces in critical care: a prospective multicenter randomized controlled trial of pleural drainage for mechanically ventilated trauma patients with occult pneumothoraces.
Kirkpatrick AW, Rizoli S, Ouellet JF, Roberts DJ, Sirois M, Ball CG, Xiao ZJ, Tiruta C, Meade M, Trottier V, Zhu G, Chagnon F, Tien H; Canadian Trauma Trials Collaborative and the Research Committee of the Trauma Association of Canada.
J Trauma Acute Care Surg. 2013 Mar;74(3):747-54; discussion 754-5. doi: 10.1097/TA.0b013e3182827158. PMID:23425731

Relationship between bradykinin-induced relaxation and endogenous epoxyeicosanoid synthesis in human bronchi.
Tabet Y, Sirois M, Sirois C, Rizcallah E, Rousseau É.
Am J Physiol Lung Cell Mol Physiol. 2013 Apr 15;304(8):L562-9. doi: 10.1152/ajplung.00379.2012. Epub 2013 Feb 15. PMID:23418089

Anti-cancer effects of a new docosahexaenoic acid monoacylglyceride in lung adenocarcinoma.
Morin C, Fortin S, Cantin AM, Sirois M, Sirois C, Rizcallah E, Rousseau É.
Recent Pat Anticancer Drug Discov. 2013 Sep;8(3):319-34. PMID:23092161

Huge malignant solitary fibrous tumor of the pleura.
Arab WA, Lamoth D, Echavé V, Rizcallah E, Sirois M.
Gen Thorac Cardiovasc Surg. 2012 Jun;60(6):397-400. doi: 10.1007/s11748-012-0014-6. Epub 2012 May 8. PMID: 22566249

Group a streptococcus causing descending necrotizing mediastinitis: report of a case and literature review.
Collin Y, Sirois M, Carignan A, Lawton Wackett JC.
Surg Infect (Larchmt). 2012 Feb;13(1):57-9. Epub 2012 Feb 8. PMID: 22316143

A multidisciplinary approach to aortoesophageal fistula: a case report.
Abu Arab W, Chagnon F, Echavé V, Dorion D, Sirois M.
Turkish J Thorac Cardiovasc Surg. 2011 19(2):285-287.

Concentration- and time-dependent effects of enoxaparin on human adenocarcinomic epithelial cell line A549 proliferation in vitro.
Abu Arab W, Kotb R, Sirois M, Rousseau E.
Can J Physiol Pharmacol. 2011 Oct;89(10):705-11. Epub 2011 Sep 9. PMID: 21905823

Surgical management of sternoclavicular joint infection.
Abu Arab W, Khadragui I, Echavé V, Deshaies A, Sirois C, Sirois M.
Eur J Cardiothorac Surg. 2011 Sep;40(3):630-4. Epub 2011 Mar 1. PMID: 21367613

17,18-epoxyeicosatetraenoic acid targets PPARγand p38 mitogen-activated protein kinase to mediate its anti-inflammatory effects in the lung: role of soluble epoxide hydrolase.
Morin C, Sirois M, Echavé V, Albadine R, Rousseau E.
Am J Respir Cell Mol Biol. 2010 Nov;43(5):564-75. Epub 2009 Dec 11. PMID: 20008283

Primary myxoid sarcoma of the pleura.
Arab WA, Echavé V, Sirois M, Bénard F, Gomes MM.
Can J Surg. 2009 Aug;52(4):E93-E94. No abstract available. PMID: 19680505

Incidental carcinoma in bullous emphysema.
Arab WA, Echavé V, Sirois M, Gomes MM.
Can J Surg. 2009 Jun;52(3):E56-7. No abstract available. PMID: 19503647  

Relaxing effects of 17(18)-EpETE on arterial and airway smooth muscles in human lung.
Morin C, Sirois M, Echave V, Rizcallah E, Rousseau E.
Am J Physiol Lung Cell Mol Physiol. 2009 Jan;296(1):L130-9. Epub 2008 Oct 31. PMID: 18978038

The OPTICC trial: a multi-institutional study of occult pneumothoraces in critical care.
Ouellet JF, Trottier V, Kmet L, Rizoli S, Laupland K, Ball CG, Sirois M, Kirkpatrick AW.
Am J Surg. 2009 May;197(5):581-6. PMID: 19306978

Morin CS, Sirois M, Echave V, Rizcallah E, Rousseau E.
Relaxing effects of 17(18)EpETE on arterial and airway smooth muscles in human lung.
Am J Physiol Lung Cell Mol Physiol. 2009 Jan;296(1):L130-9. Epub 2008 Oct 31.

Morin C, Sirois M, Echave V, Rousseau E.
CPI-17 silencing-reduced responsiveness in control and TNF-alpha-treated human bronchi.
Am J Respir Cell Mol Biol. 2008 Dec;39(6):638-43.

Morin C, Guibert C, Sirois M, Echave V, Gomes MM, Rousseau E.
Effects of {omega}-hydroxylase product on distal human pulmonary arteries.
Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1435-43. Epub 2008 Jan 18.

Morin C, Sirois M, Echave V, Gomes MM, Rousseau E.
EET displays anti-inflammatory effects in TNF-alpha stimulated human bronchi: putative role of CPI-17.
Am J Respir Cell Mol Biol. 2008 Feb;38(2):192-201. Epub 2007 Sep 13.

Morin C, Sirois M, Echave V, Gomes MM, Rousseau E.
Functional effects of 20-HETE on human bronchi: hyperpolarization and relaxation due to BKCa channel activation.
Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L1037-44. Epub 2007 Jul 27.

Morin C, Sirois M, Echave V, Gomes MM, Rousseau E.
Epoxyeicosatrienoic acid relaxing effects involve Ca2+-activated K+ channel activation and CPI-17 dephosphorylation in human bronchi.
Am J Respir Cell Mol Biol. 2007 May;36(5):633-41. Epub 2007 Jan 19.

Morin C, Sirois M, Echave V, Gomes MM, Rousseau E.
Relaxing effects of 5-oxo-ETE on human bronchi involve BK Ca channel activation.
Prostaglandins Other Lipid Mediat. 2007 Jun;83(4):311-9. Epub 2007 Mar 7.

Kirkpatrick AW, Sirois M, Laupland KB, Goldstein L, Brown DR, Simons RK, Dulchavsky S, Boulanger BR.
Prospective evaluation of hand-held focused abdominal sonography for trauma (FAST) in blunt abdominal trauma.
Can J Surg. 2005 Dec;48(6):453-60.

Kirkpatrick AW, Sirois M, Ball CG, Laupland KB, Goldstein L, Hameed M, Brown DR, Simons RK, Kortbeek J, Dulchavsky S, Boulanger BB.
The hand-held ultrasound examination for penetrating abdominal trauma.
Am J Surg. 2004 May;187(5):660-5.

Chun R, Kirkpatrick AW, Sirois M, Sargasyn AE, Melton S, Hamilton DR, Dulchavsky S.
Where's the tube? Evaluation of hand-held ultrasound in confirming endotracheal tube placement.
Prehospital Disaster Med. 2004 Oct-Dec;19(4):366-9.

Kirkpatrick AW, Sirois M, Laupland KB, Liu D, Rowan K, Ball CG, Hameed SM, Brown R, Simons R, Dulchavsky SA, Hamiilton DR, Nicolaou S.
Hand-held thoracic sonography for detecting post-traumatic pneumothoraces: the Extended Focused Assessment with Sonography for Trauma (EFAST).
J Trauma. 2004 Aug;57(2):288-95.