Voici la liste des publications récentes des professeurs du service de neurologie du Département de médecine. Les cliniciens et les professeurs-chercheurs avec octrois de ce service sont en caractères gras. Les professeurs associés à ce service sont en italique.

Dernière mise à jour :11 jan 2021


1.      Belleville, S., A.C. LeBlanc, M.-J. Kergoat, F. Calon, P. Gaudreau, S.S. Hébert, C. Hudon, Cunnane S C, Bocti C et al. « The Consortium for the early identification of Alzheimer’s disease–Quebec (CIMA-Q) ». Alzheimer’s and Dementia: Diagnosis, Assessment and Disease Monitoring 11 (2019): 787‑96.

2.      Coutts, Shelagh B., Moreau F, Negar Asdaghi, Boulanger JM, Marie-Christine Camden, Bruce C. V. Campbell, Andrew M. Demchuk, et al. « Rate and Prognosis of Brain Ischemia in Patients With Lower-Risk Transient or Persistent Minor Neurologic Events ». JAMA Neurology, 23 septembre 2019.

3.      Diener, H-C  Ralph L. Sacco, J. Donald Easton, Granger C-B , Richard A. Bernstein, Shinichiro Uchiyama, Kreuzer J, Boulanger JM et al. « Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. » The New England Journal of Medicine 380, no 20 (16 mai 2019): 1906‑17.

4.      Dupont, Pénélope S., Bocti C, Maude Joannette, Marie Maxime Lavallée, Jim Nikelski, Guillaume T. Vallet, Howard Chertkow, et Sven Joubert. « Amyloid Burden and White Matter Hyperintensities Mediate Age-Related Cognitive Differences ». Neurobiology of Aging, 31 août 2019.

5.      Fortier, M, Castellano CA,  Croteau E, Langlois FBocti, C, St-Pierre V, Vandenberghe C, Cunnane S , Fulop T et al. 2019. « A Ketogenic Drink Improves Brain Energy and Some Measures of Cognition in Mild Cognitive Impairment ». Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, février.

6.      Gensicke, Henrik, James W. Evans, Fahad S. Al Ajlan, Dar Dowlatshahi, Mohamed Najm, Ana L. Calleja, Josep Puig, Boulanger JM et al. « Comparison of Different Methods of Thrombus Permeability Measurement and Impact on Recanalization in the INTERRSeCT Multinational Multicenter Prospective Cohort Study ». Neuroradiology, 12 novembre 2019.

7.      Gharagozloo, M., S. Mahmoud, C. Simard, K. Yamamoto, D. Bobbala, S. Ilangumaran, M.D. Smith, Lamontagne A, Jarjoura S et al. « NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity ». PLoS Biology 17, no 9 (2019).

8.      Hu, X.Y., L. Rajendran, Lapointe E, R. Tam, D. Li, A. Traboulsee, et A. Rauscher. « Three-dimensional MRI sequences in MS diagnosis and research ». Multiple Sclerosis Journal 25, no 13 (2019): 1700‑1709.

9.      Joannette, Maude, Bocti C,, Pénélope S. Dupont, Marie M. Lavallée, Jim Nikelski, Guillaume T. Vallet, Howard Chertkow, et Sven Joubert. « Education as a Moderator of the Relationship between Episodic Memory and Amyloid Load in Normal Aging ». The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 23 octobre 2019.

10.  Lafortune, Jeanne, Deacon C, et Jean-François Clément. « Brivaracetam: First Canadian Experience in an Intractable Epilepsy Population ». The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques, 5 novembre 2019, 1‑6.

11.  Levesque, Mathieu, Christian Iorio-Morin, Bocti, C, Caroline Vézina, et Deacon C.  « Nonepileptic, Stereotypical, and Intermittent Symptoms (NESIS) in Patients With Subdural Hematoma: Proposal for a New Clinical Entity With Therapeutic and Prognostic Implications ». Neurosurgery, 25 septembre 2019.

12.  Levy, Jake P., Bocti C, Dominique Elie, Nancy Paquet, Jean-Paul Soucy, et Simon Ducharme. « Bifrontal Hypermetabolism on Brain FDG-PET in a Case of C9orf72-Related Behavioral Variant of Frontotemporal Dementia ». The Journal of Neuropsychiatry and Clinical Neurosciences 31, no 1 (Winter 2019): 92‑94.

13.  Nolze-Charron, Geneviève, Raphaël Dufort-Rouleau, Jean-Christophe Houde, Matthieu Dumont, Christian-Alexandre Castellano, Cunnane S-C , Dominique Lorrain, Fülöp T, Maxime Descoteaux, et Bocti C. « Tractography of the External Capsule and Cognition: A Diffusion MRI Study of Cholinergic Fibers ». Experimental Gerontology 130 (février 2020): 110792.

14.  Rahayel, Shady, Bocti, C, Penelope Sevigny Dupont, Maude Joannette, Marie Maxime Lavallee, Jim Nikelski, Howard Chertkow, et Sven Joubert. « Subcortical Amyloid Load Is Associated with Shape and Volume in Cognitively Normal Individuals. » Human Brain Mapping, 30 mai 2019.

15.  Yogendrakumar, V., F. Al-Ajlan, M. Najm, J. Puig, A. Calleja, S.-I. Sohn, S.H. Ahn, JM Boulanger et al. 2019. « Clot burden score and early ischemia predict intracranial hemorrhage following endovascular therapy ». American Journal of Neuroradiology 40 (4): 655‑60.

16.  Yogendrakumar, Vignan, Tim Ramsay, Dean Fergusson, Andrew M. Demchuk, Richard I. Aviv, David Rodriguez-Luna, Carlos A. Molina, JM Boulanger  et al. « New and Expanding Ventricular Hemorrhage Predicts Poor Outcome in Acute Intracerebral Hemorrhage ». Neurology 93, no 9 (27 août 2019): e879‑88.

17.  Yogendrakumar, V., T. Ramsay, D.A. Fergusson, A.M. Demchuk, R.I. Aviv, D. Rodriguez-Luna, C.A. Molina, JM Boulanger et al. « Independent Validation of the Hematoma Expansion Prediction Score: A Non-contrast Score Equivalent in Accuracy to the Spot Sign ». Neurocritical Care 31, no 1 (2019).

18.  Zukotvnski, K., V.C. Gaudet, P. Kuo, S. Adamo, M. Goubran, Bocti, C, M. Borrie, et al. « Non-Binary Approaches for Classification of Amyloid Brain PET », 2019-May:206‑11, 2019.

19.  Zukotynski K1, Gaudet VKuo PHAdamo SGoubran MScott CBocti CBorrie MChertkow HFrayne RHsiung RLaforce R JrNoseworthy MDPrato FSSahlas DJSmith EESossi VThiel ASoucy JPTardif JCBlack SE1; 2019  The Use of Random Forests to Classify Amyloid Brain PET. Clin Nucl Med. 2019 Jul 24.


  • Bizeau, Alexandre, Guillaume Gilbert, Michaël Bernier, Minh Tung Huynh, Christian Bocti, Maxime Descoteaux, et Kevin Whittingstall. « Stimulus-Evoked Changes in Cerebral Vessel Diameter: A Study in Healthy Humans ». Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 38, no 3 (mars 2018): 528‑39.
  • Boulanger, J.M., M.P. Lindsay, G. Gubitz, E.E. Smith, G. Stotts, N. Foley, S. Bhogal, et al. « Canadian Stroke Best Practice Recommendations for Acute Stroke Management: Prehospital, Emergency Department, and Acute Inpatient Stroke Care, 6th Edition, Update 2018 ». Article in Press, 2018. Scopus.
  • Croteau, Etienne, Christian-Alexandre Castellano, Marie Anne Richard, Mélanie Fortier, Scott Nugent, Martin Lepage, Simon Duchesne,  Christian Bocti, Tamas Fulop, Stephen C Cunnane. « Ketogenic Medium Chain Triglycerides Increase Brain Energy Metabolism in Alzheimer’s Disease ». Journal of Alzheimer’s Disease: JAD 64, no 2 (2018): 551‑61.
  • Dowlatshahi, Dar, Anirudda Deshpande, Richard I. Aviv, David Rodriguez-Luna, Carlos A. Molina, Yolanda Silva Blas, Imanuel Dzialowski, Jean-Martin Boulanger et al. « Do Intracerebral Hemorrhage Nonexpanders Actually Expand Into the Ventricular Space? » Stroke 49, no 1 (2018): 201‑3.
  • Fulop, Tamas, Jacek M. Witkowski, Karine Bourgade, Abdelouahed Khalil, Echarki Zerif, Anis Larbi, Katsuiku Hirokawa, Bocti Christian, Lacombe Guy et al. « Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer’s Disease? » Frontiers in Aging Neuroscience 10 (2018): 224.
  • Imbeault, Hélène, Francis Langlois, Christian Bocti, Lise Gagnon, et Nathalie Bier. « Can People with Alzheimer’s Disease Improve Their Day-to-Day Functioning with a Tablet Computer? » Neuropsychological Rehabilitation 28, no 5 (juillet 2018): 779‑96.
  • Johnston, S. Claiborne, J. Donald Easton, Mary Farrant, William Barsan, Robin A. Conwit, Jordan J. Elm, Anthony S. Kim, Anne S. Lindblad, Yuko Y. Palesch, Boulanger, J.M.,  et Clinical Research Collaboration, Neurological Emergencies Treatment Trials Network, and the POINT Investigators. « Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA ». The New England Journal of Medicine 379, no 3 (19 2018): 215‑25.
  • Léveillé-, Pauline, Mathieu Hamel, Jean-Luc Ardilouze, Jean-Charles Pasquier, Charles Deacon, Kevin Whittingstall, et Mélanie Plourde. « Pilot Study of EEG in Neonates Born to Mothers with Gestational Diabetes Mellitus ». International Journal of Developmental Neuroscience: The Official Journal of the International Society for Developmental Neuroscience, 19 janvier 2018.
  •  Leveille E, Gonorazky HD, Rioux M-F, Hazrati L-N, Ruskey JA, Carnevale A, et al. Triple A syndrome presenting as complicated hereditary spastic paraplegia. Mol Genet Genomic Med. 2018;
  • Lin, K., P. Lindsay, T. Shams, E. Smith, J.-M. Boulanger, K. Butcher, G. Gubitz, et E. Lang. « A summary of the Canadian Stroke Best Practice Recommendations, Sixth Edition (2018): Updates relevant to prehospital and emergency medicine providers ». Canadian Journal of Emergency Medicine 20, no 5 (2018): 685‑92.
  • Masse, Marie-Hélène, Marie Anne Richard, Frédérick D’Aragon, Charles St-Arnaud, Michael Mayette, Neill K. J. Adhikari, William Fraser,  André Carpentier; Steven Palanchuck; David Gauthier; Luc Lanthier; Matthieu Touchette; Albert Lamontagne; Jean Chénard; Sangeeta Mehta; Yanick Sansoucy; Etienne Croteau; Martin Lepage; François Lamontagne. « Early Evidence of Sepsis-Associated Hyperperfusion-A Study of Cerebral Blood Flow Measured With MRI Arterial Spin Labeling in Critically Ill Septic Patients and Control Subjects ». Critical Care Medicine, 6 avril 2018.
  • Tanguay Bernard, Marie-Michèle, Mireille Luc, Jean-Daniel Carrier, Louise Fournier, Arnaud Duhoux, Elodie Côté, Olivier Lessard, Catherine Gibeault, Christian Bocti, et Pasquale Roberge. « Patterns of Benzodiazepines Use in Primary Care Adults with Anxiety Disorders ». Heliyon 4, no 7 (juillet 2018): e00688.
  • Yogendrakumar, Vignan, Eric E. Smith, Andrew M. Demchuk, Richard I. Aviv, David Rodriguez-Luna, Carlos A. Molina, Yolanda Silva Blas, Jean-Martin Boulanger et al. « Lack of Early Improvement Predicts Poor Outcome Following Acute Intracerebral Hemorrhage ». Critical Care Medicine, 4 janvier 2018.


Bergeron, D., Flynn, K., Verret, L., Poulin, S., Bouchard, R.W., Bocti, C., Fülöp, T., Lacombe, G., Gauthier, S., Nasreddine, Z., Laforce, R.J., 2017. Multicenter Validation of an MMSE-MoCA Conversion Table. J. Am. Geriatr. Soc. 65, 1067–1072. 

Bocti, C., Pépin, F., Tétreault, M., Cossette, P., Langlois, F., Imbeault, H., Duval, N., Lacombe, G., Fulop, T., (2017). Orthostatic hypotension associated with executive dysfunction in mild cognitive impairment. J. Neurol. Sci. 382:79–83. URL:

Castellano, C.-A., Paquet, N., Dionne, I.J., Imbeault, H., Langlois, F., Croteau, E., Tremblay, S., Fortier, M., Matte, J.J., Lacombe, G., Fülöp, T., Bocti, C., Cunnane, S.C., 2017. A 3-Month Aerobic Training Program Improves Brain Energy Metabolism in Mild Alzheimer’s Disease: Preliminary Results from a Neuroimaging Study. J. Alzheimers. Dis. 56, 1459–1468. 

Croteau, E., Castellano, C.A., Fortier, M., Bocti, C., Fulop, T., Paquet, N., Cunnane, S.C., 2017. EPUB - A cross-sectional comparison of brain glucose and ketone metabolism in cognitively healthy older adults, mild cognitive impairment and early Alzheimer’s disease. Exp. Gerontol. 

Dowlatshahi, D., Deshpande, A., Aviv, R.I., Rodriguez-Luna, D., Molina, C.A., Blas, Y.S., Dzialowski, I., Kobayashi, A., Boulanger, J.-M., Lum, C., Gubitz, G.J., Padma, V., Roy, J., Kase, C.S., Bhatia, R., Hill, M.D., Demchuk, A.M., (2017). EPUB - Do Intracerebral Hemorrhage Nonexpanders Actually Expand Into the Ventricular Space? Stroke URL:

Easton, J.D., Aunes, M., Albers, G.W., Amarenco, P., Bokelund-Singh, S., Denison, H., Evans, S.R., Held, P., Jahreskog, M., Jonasson, J., Minematsu, K., Molina, C.A., Wang, Y., Wong, K.S.L., Johnston, S.C., SOCRATES Steering Committee and Investigators [Jean-Martin Boulanger], (2017). Risk for Major Bleeding in Patients Receiving Ticagrelor Compared With Aspirin After Transient Ischemic Attack or Acute Ischemic Stroke in the SOCRATES Study (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcome. Circulation 136(10):907–916. URL:

Epstein, K.A., Viscoli, C.M., Spence, J.D., Young, L.H., Inzucchi, S.E., Gorman, M., Gerstenhaber, B., Guarino, P.D., Dixit, A., Furie, K.L., Kernan, W.N., IRIS Trial Investigators [Boulanger, J.-M.], (2017). Smoking cessation and outcome after ischemic stroke or TIA. Neurology 89(16):1723–1729. URL:

Fatehi, F., Salort-Campana, E., Le Troter, A.,Lareau-Trudel, E., Bydder, M., Fouré, A., Guye, M., Bendahan, D., Attarian, S., (2017). Long-term follow-up of MRI changes in thigh muscles of patients with Facioscapulohumeral dystrophy: A quantitative study. PLoS One 12(8):e0183825. URL:

Lajoie, I., Nugent, S., Debacker, C., Dyson, K., Tancredi, F.B., Badhwar, A., Belleville, S., Deschaintre, Y., Bellec, P., Doyon, J., Bocti, C., Gauthier, S., Arnold, D., Kergoat, M.-J., Chertkow, H., Monchi, O., Hoge, R.D., 2017. Application of calibrated fMRI in Alzheimer’s disease. NeuroImage. Clin. 15, 348–358. 

Lanthier, S., Saposnik, G., Lebovic, G., Pope, K., Selchen, D., Moore, D.F., Canadian Fabry Stroke Screening Initiative Study Group [Boulanger, J.-M.,Gosselin, S.], 2017. Prevalence of Fabry Disease and Outcomes in Young Canadian Patients With Cryptogenic Ischemic Cerebrovascular Events. Stroke 48, 1766–1772. 

Leung, A.A., Daskalopoulou, S.S., Dasgupta, K., McBrien, K., Butalia, S., Zarnke, K.B., Nerenberg, K., Harris, K.C., Nakhla, M., Cloutier, L., Gelfer, M., Lamarre-Cliche, M., Milot, A., Bolli, P., Tremblay, G., McLean, D., Tobe, S.W., [...], Boulanger, J.-M., Prebtani, A., Kline, G., Leiter, L.A., Jones, C., Côté, A.-M., et al. Hypertension Canada, 2017. Hypertension Canada’s 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults. Can. J. Cardiol. 33, 557–576. 

[1] Les publications issues d’une collaboration inter-services sont répertoriées dans chacun des services impliqués.

[2] La liste des auteurs a parfois été raccourcie par […] ou et al. par soucis d’espace.


Arba, F., Palumbo, V., Boulanger, J.-M., Pracucci, G., Inzitari, D., Buchan, A.M., Hill, M.D., CASES Investigators, 2016. Leukoaraiosis and lacunes are associated with poor clinical outcomes in ischemic stroke patients treated with intravenous thrombolysis. Int. J. Stroke 11, 62–7.

Beaulieu-Boire, I., Aquino, C.C., Fasano, A., Poon, Y.-Y., Fallis, M., Lang, A.E., Hodaie, M., Kalia, S.K., Lozano, A., Moro, E., 2016. Deep Brain Stimulation in Rare Inherited Dystonias. Brain Stimul. 9, 905–910.             

Bourgade, K., Le Page, A., Bocti, C., Witkowski, J.M., Dupuis, G., Frost, E.H., Fülöp, T., 2016. Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model. J. Alzheimers. Dis. 50, 1227–41.       

Casaubon, L.K., Boulanger, J.-M., Glasser, E., Blacquiere, D., et al., 2016. Canadian Stroke Best Practice Recommendations: Acute Inpatient Stroke Care Guidelines, Update 2015. Int. J. stroke 11, 239–52.         

Choquet, K., Tétreault, M., Yang, S., La Piana, R., Dicaire, M.-J., Vanstone, M.R., Mathieu, J., Bouchard, J.-P., Rioux, M.-F., Rouleau, G.A., Care4Rare Canada Consortium, Boycott, K.M., Majewski, J., Brais, B., 2016. SPG7 mutations explain a significant proportion of French Canadian spastic ataxia cases. Eur. J. Hum. Genet. 24, 1016–21.

Cunnane, S.C., Courchesne-Loyer, A., Vandenberghe, C., St-Pierre, V., Fortier, M., Hennebelle, M., Croteau, E., Bocti, C., Fulop, T., Castellano, C.-A., 2016. Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease. Front. Mol. Neurosci. 9, 53.            

Dowlatshahi, D., Yogendrakumar, V., Aviv, R.I., Rodriguez-Luna, D., Molina, C.A., Silva, Y., Dzialowski, I., Czlonkowska, A., Boulanger, J.-M., Lum, C., Gubitz, G., Padma, V., Roy, J., Kase, C.S., Bhatia, R., Hill, M.D., Demchuk, A.M., PREDICT/Sunnybrook ICH CTA study group, 2016. Small intracerebral hemorrhages have a low spot sign prevalence and are less likely to expand. Int. J. Stroke 11, 191–7.              

Imbeault, H., Gagnon, L., Pigot, H., Giroux, S., Marcotte, N., Cribier-Delande, P., Duval, J., Bocti, C., Lacombe, G., Fülöp, T., Bier, N., 2016. Impact of AP@LZ in the daily life of three persons with Alzheimer’s disease: long-term use and further exploration of its effectiveness. Neuropsychol. Rehabil. 1–24.             

Imbeault, H., Langlois, F., Bocti, C., Gagnon, L., Bier, N., 2016. Can people with Alzheimer’s disease improve their day-to-day functioning with a tablet computer? Neuropsychol. Rehabil. 1–18.    

Lapointe, E., Deacon, C., Royer-Perron, L., Cunnane, S., Castellano, C.-A., Bocti, C., 2016. Temporal Lobe Atrophy May Be Underrecognized in Older Patients with New-Onset Epilepsy. Can. J. Neurol. Sci. / J. Can. des Sci. Neurol. 43, 731–734.   

Leung, A.A., Nerenberg, K., Daskalopoulou, S.S., McBrien, K., Zarnke, K.B., Dasgupta, K., Cloutier, L., Gelfer, M., […], Boulanger, J.-M., et al., 2016. Hypertension Canada’s 2016 Canadian Hypertension Education Program Guidelines for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension. Can. J. Cardiol. 32, 569–88.

Léveillé, P., Ardilouze, J.-L., Pasquier, J.-C., Deacon, C., Whittingstall, K., Plourde, M., 2016. Fatty acid profile in cord blood of neonates born to optimally controlled gestational diabetes mellitus. Prostaglandins, Leukot. Essent. Fat. Acids 115, 48–52.                         

Lévesque, S., Auray-Blais, C., Gravel, E., Boutin, M., Dempsey-Nunez, L., Jacques, P.-E., Chenier, S., Larue, S., Rioux, M.-F., Al-Hertani, W., Nadeau, A., Mathieu, J., Maranda, B., Désilets, V., Waters, P.J., Keutzer, J., Austin, S., Kishnani, P., 2016. Diagnosis of late-onset Pompe disease and other muscle disorders by next-generation sequencing. Orphanet J. Rare Dis. 11, 8.             

Moreau, F., Yang, R., Nambiar, V., Demchuk, A.M., Dunn, J.F., 2016. Near-infrared measurements of brain oxygenation in stroke. Neurophotonics 3, 31403.

Nugent, S., Castellano, C.A., Bocti, C., Dionne, I., Fulop, T., Cunnane, S.C., 2016. Relationship of metabolic and endocrine parameters to brain glucose metabolism in older adults: do cognitively-normal older adults have a particular metabolic phenotype? Biogerontology 17, 241–55.          

Rodriguez-Luna, D., Coscojuela, P., Rubiera, M., Hill, M.D., Dowlatshahi, D., Aviv, R.I., Silva, Y., Dzialowski, I., Lum, C., Czlonkowska, A., Boulanger, J.-M., Kase, C.S., Gubitz, G., Bhatia, R., Padma, V., Roy, J., Tomasello, A., Demchuk, A.M., Molina, C.A., PREDICT/Sunnybrook ICH CTA Study Group, 2016. Ultraearly hematoma growth in active intracerebral hemorrhage. Neurology 87, 357–64.         

Rodriguez-Luna, D., Stewart, T., Dowlatshahi, D., Kosior, J.C., Aviv, R.I., Molina, C.A., Silva, Y., Dzialowski, I., Lum, C., Czlonkowska, A., Boulanger, J.-M., Kase, C.S., Gubitz, G., Bhatia, R., Padma, V., Roy, J., Subramaniam, S., Hill, M.D., Demchuk, A.M., PREDICT/Sunnybrook ICH CTA Study Group, 2016. Perihematomal Edema Is Greater in the Presence of a Spot Sign but Does Not Predict Intracerebral Hematoma Expansion. Stroke 47, 350–5.            

[1] Les publications issues d’une collaboration inter-services sont répertoriées dans chacun des services impliqués.

[2] La liste des auteurs a parfois été raccourcie par […] ou et al. par soucis d’espace.