Pr Gilles Boire, M.D., M. Sc.
Professeur titulaire

Membre de l'axe de recherche et du thème porteur "Inflammation-douleur" du CRC-Étienne LeBel du CHUS et de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke.
Service de rhumatologie
Département de médecine
Faculté de médecine et des sciences de la santé
Université de Sherbrooke
3001, 12e Avenue Nord
Sherbrooke (Québec)  J1H 5N4

Téléphone : 819 564-5261
Télécopieur : 819 564-5265

Courriel : Gilles.Boire@USherbrooke.ca

Site Internet
Appartenances mineures
  • Département de biochimie
  • Service d'immunologie
  • Département de pédiatrie
Études médicales et postdoctorales

Université de Sherbrooke

Fellowship

Yale University (Dr Joe Craft/Dr John A. Hardin)

Maîtrise en Sciences cliniques

Université de Sherbrooke

Thèmes de recherche
  • Antigénicité et fonction des petits ARN non codants hY.
  • Biomarqueurs et déterminants psychosociaux dans les issues cliniques dans la polyarthrite inflammatoire d'installation récente.
  • Prévention secondaire des fractures de fragilité osseuse.
Axe et thème porteur de recherche

Inflammation et douleur

Subventions de recherche en cours

Early prediction of patient-related and radiological outcomes in patients with recent-onset inflammatory polyarthritis (EPA) using established and novel independent predictors.

Chercheur principal :  Boire G
Co-chercheurs : Cossette P, Daniel C, de Brum-Fernandes A, Dobkin PL, Kurgan L, Ménard HA, Arsenault G, Liang P, Bruns A.

Organisme subventionnaire :
IRSC
(03/2011-03/2016)

Partnership for applied research in fracture prevention programs for the elderly.

Chercheurs principaux :  Gaboury I, Poirier A, Corriveau H
Co-chercheurs : Beaulieu M-C, Cabana F, Boire G, et al.

Organisme subventionnaire :
IRSC
(04/2012-03/2015)

Developing Advanced Methods for Population-Based Comparative Effectiveness Studies.

Chercheurs principaux :  Abrahamowicz MMA (Univ. McGill), Bernatsky SR, Lacaille DV, Levy AR, Moride Y, Pilote L
Co-chercheurs : Boire G, et al.

Organisme subventionnaire :
Subvention d'équipe
IRSC/CIHR
(09/2011-08/2014)

Empowering Patients as Active Partners in Their Care: Lupus Interactive Navigator (LIN).

Chercheurs principaux :  Bergeron L, da Costa DM, Fortin PR (Univ. Laval)
Co-chercheurs : Boire G, et al.

Organisme subventionnaire :
Partenariat pour l'amélioration du système de santé (PASS)
IRSC/CIHR
(04/2011-03/2014)

The role of Y RNA-related sequences in shaping genomes.

Chercheur principal :  Boire G

Organisme subventionnaire :
CRSNG et CRSH
(04/2008-03/2013)

Liens entre l'exercice, l'activité et la physiopathologie chez les enfants atteints d'arthrite juvénile.

Chercheur principal : Duffy C
Co-chercheur local : Boire G

Organisme commanditaire :
IRSC/CIHR
(05/2012-12/2014)

Étude in vitro de l'effet des immunoglobulines pour injection intraveineuse (IVIg) sur les lymphocytes B de patients atteints de lupus érythémateux disséminé.

Chercheur principal :  Boire G
Co-chercheurs :  Liang P, Roux S, et al.

Organisme subventionnaire :
Héma-Québec

Commandites de recherche en cours

Longueur des télomères des cellules du sang périphérique de patients avec arthrite inflammatoire débutante.

Chercheur principal :  Boire G

Organisme commanditaire :
Janssen Canada
(2011-....)

Ostéoporose et fractures périphériques : traitement et investigation multidisciplinaire au CHUS (OPTIMUS).

Chercheur principal :  Boire G

Organisme commanditaire :
Merck Frosst Canada et Alliance Aventis / Proctor & Gamble / Novartis Pharma Canada / Servier Canada / Amgen Canada.
(2006-....)

Validation prospective de biomarqueurs solubles comme prédicteurs de dommages structuraux dans la polyarthrite rhumatoïde.

Chercheur principal : Boire G

Organisme commanditaire :
CARE Arthritis
(2012-....)

Supervision d'étudiants/5 dernières années

(2e, 3e cycles et stagiaires postdoctoraux)
Osborne, Alexandre

Programme : Sciences cliniques

Diplôme : M. Sc. / en cours

Titre de la recherche : Évaluation de l'impact du nombre de cercles d'excision thymiques (TREC) et du raccourcissement des télomères sur les issues clliniques de la polyarthrite inflammatoire débutante.

Bourse : S/O

Directeur : Boire G

Haouari, Rym

Programme : Rhumatologie

Diplôme : Fellow postdoctoral / en cours

Titre de la recherche : Echographic characterization of the lateral hip pain syndrome.

Bourse : S/O

Directeur : Boire G

Supervision terminée
Bergeron, Claudie

Programme : Rhumatologie

Diplôme : Fellow postdoctoral / fin 07/2012

Titre de la recherche : Role of echography to assess risk of recurrence on drug withdrawal in RA patients in remission.

Bourse : S/O

Co-Directeur : Boire G

Bissonnette, Lyne

Programme : Rhumatologie

Diplôme : Fellow postdoctoral / fin 07/2013

Titre de la recherche : Osteoclast apoptosis.

Bourse : S/O

Co-Directeur : Boire G

Giguère, Tamara

Programme : Biochimie

Diplôme : M. Sc. obtenue en 2013

Titre de la recherche : Y RNAs as microRNAs.

Bourse : S/O

Directeur : Boire G

Guzian, Marie-Caroline

Programme :

Diplôme : Fellow postdoctoral / fin 2010

Titre de la recherche : Marqueurs pronostiques dans la polyarthrite débutante.

Bourse : Pfizer Canada du Département de médecine (2008-2009)

Directeur : Boire G

Lamontagne, Anne-Marie

Programme : Biochimie

Diplôme : M. Sc. obtenue en 2011

Titre de la recherche : The role of Y RNA sequences in shaping genomes.

Bourse : S/O

Directeur : Boire G
Co-directeur : Perreault JP

Leclerc, Valérie

Programme : Rhumatologie

Diplôme : Fellow postdoctoral / fin 03/2012

Titre de la recherche : Use of allopurinol start during an acute gouty attack.

Bourse : --

Co-Directeur : Boire G

Roy, Lucie

Programme : Rhumatologie

Diplôme : Fellow postdoctoral / fin 09/2013

Titre de la recherche : Allopurinol use in acute gouty attacks.

Bourse : S/O

Co-Directeur : Boire G

Publications d'articles (2009-...)

Physician global assessment at 3 months is strongly predictive of remission at 12 months in early rheumatoid arthritis: results from the CATCH cohort.
Choy T, Bykerk VP, Boire G, Haraoui BP, Hitchon C, Thorne C, Keystone EC, Pope JE; on behalf of CATCH Investigators.
Rheumatology (Oxford). 2013 Nov 15. [Epub ahead of print] PMID:24241035

Determining best practices in early rheumatoid arthritis by comparing differences in treatment at sites in the canadian early arthritis cohort.
Harris JA, Bykerk VP, Hitchon CA, Keystone EC, Thorne JC, Boire G, Haraoui B, Hazlewood G, Bonner AJ, Pope JE; CATCH Investigators.
J Rheumatol. 2013 Nov;40(11):1823-30. doi: 10.3899/jrheum.121316. Epub 2013 Sep 15. PMID:24037554

Factors associated with time to diagnosis in early rheumatoid arthritis.
Barnabe C, Xiong J, Pope JE, Boire G, Hitchon C, Haraoui B, Carter Thorne J, Tin D, Keystone EC, Bykerk VP; Canadian early ArThritis CoHort (CATCH) Study Investigators.
Rheumatol Int. 2013 Aug 30. [Epub ahead of print] PMID:23989941

The Relationship Between Function and Disease Activity as Measured by the HAQ and DAS28 Varies Over Time and by Rheumatoid Factor Status in Early Inflammatory Arthritis (EIA). Results from the CATCH Cohort.
Boyd TA, Bonner A, Thorne C, Boire G, Hitchon C, Haraoui BP, Keystone EC, Bykerk VP, Pope JE.
Open Rheumatol J. 2013 Aug 28;7:58-63. doi: 10.2174/1874312901307010058. PMID:24044031

Atypical fracture of the tibial diaphysis associated with bisphosphonate therapy: a case report.
Bissonnette L, April PM, Dumais R, Boire G, Roux S.
Bone. 2013 Oct;56(2):406-9. doi: 10.1016/j.bone.2013.07.012. Epub 2013 Jul 17. PMID:23871749

Therapies for active rheumatoid arthritis after methotrexate failure.
O'Dell JR, Mikuls TR, Taylor TH, Ahluwalia V, Brophy M, Warren SR, Lew RA, Cannella AC, Kunkel G, Phibbs CS, Anis AH, Leatherman S, Keystone E; CSP 551 RACAT Investigators (Boire G).
N Engl J Med. 2013 Jul 25;369(4):307-18. doi: 10.1056/NEJMoa1303006. Epub 2013 Jun 11. PMID: 23755969

Prevention of rheumatoid arthritis: the very first steps.
Masetto A, Beaulieu MC, Boire G.
J Rheumatol. 2013 Jun;40(6):752-4. doi: 10.3899/jrheum.130326. No abstract available. PMID:23728185

Brief report: ultraviolet radiation exposure is associated with clinical and autoantibody phenotypes in juvenile myositis.
Shah M, Targoff IN, Rice MM, Miller FW, Rider LG; Childhood Myositis Heterogeneity Collaborative Study Group (Boire G).
Arthritis Rheum. 2013 Jul;65(7):1934-41. doi: 10.1002/art.37985. PMID: 23658122

NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production.
Yougbaré I, Boire G, Roy M, Lugnier C, Rouseau E.
Can J Physiol Pharmacol. 2013 May;91(5):353-61. doi: 10.1139/cjpp-2012-0233. Epub 2013 Jan 2. PMID: 23656347

Priming primary care physicians to treat osteoporosis after a fragility fracture: an integrated multidisciplinary approach.
Roux S, Beaulieu M, Beaulieu MC, Cabana F, Boire G.
J Rheumatol. 2013 May;40(5):703-11. doi: 10.3899/jrheum.120908. Epub 2013 Mar 15. PMID: 23504379

Anticitrullinated Protein Antibodies and Rheumatoid Factor Fluctuate in Early Inflammatory Arthritis and Do Not Predict Clinical Outcomes.
Barra L, Bykerk V, Pope JE, Haraoui BP, Hitchon CA, Thorne JC, Keystone EC, Boire G; , and the CATCH Investigators.
J Rheumatol. 2013 Aug;40(8):1259-67. doi: 10.3899/jrheum.120736. Epub 2013 Feb 1. [Epub ahead of print] PMID: 23378461

Partnership for fragility bone fracture care provision and prevention program (P4Bones): study protocol for a secondary fracture prevention pragmatic controlled trial.
Gaboury I, Corriveau H, Boire G, Cabana F, Beaulieu MC, Dagenais P, Gosselin S, Bogoch E, Rochette M, Filiatrault J, Laforest S, Jean S, Fansi A, Theriault D, Burnand B.
Implement Sci. 2013 Jan 24;8(1):10. [Epub ahead of print] PMID: 23343392

Predictors of pain for patients with early inflammatory polyarthritis.
Dobkin PL, Liu A, Abrahamowicz M, Carrier N, de Brum-Fernandes AJ, Cossette P, Boire G.
Arthritis Care Res (Hoboken). 2013 Jun;65(6):992-9. doi: 10.1002/acr.21923. [Epub ahead of print] PMID: 23281243

Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: the In Vitro osteoclast differentiation in arthritis (IODA) study.
Durand M, Komarova SV, Bhargava A, Li K, Fiorino C, Maria O, Nabavi N, Manolson MF, Harrison RE, Jeffrey Dixon S, Sims SM, Mizianty MJ, Kurgan L, Haroun S, Boire G, de Fatima Lucena-Fernandes M, Brum-Fernandes AJ.
Arthritis Rheum. 2013 Jan;65(1):148-58. doi: 10.1002/art.37722. Epub ahead of print PMID: 23044761

The clinical phenotypes of the juvenile idiopathic inflammatory myopathies.
Shah M, Mamyrova G, Targoff IN, Huber AM, Malley JD, Rice MM, Miller FW, Rider LG;Childhood Myositis Heterogeneity Collaborative Study Group (Boire G).
Medicine (Baltimore). 2013 Jan;92(1):25-41. doi: 10.1097/MD.0b013e31827f264d.

Increasing Treatment in Early Rheumatoid Arthritis Is Not Determined by the Disease Activity Score But by Physician Global Assessment: Results from the CATCH Study.
Pyne L, Bykerk VP, Boire G, Haraoui B, Hitchon C, Thorne JC, Keystone EC, Pope JE; for the CATCH Investigators.
J Rheumatol. 2012 Nov;39(11):2081-2087. Epub 2012 Sep 1. PMID: 22942265

Time to Disease-modifying Antirheumatic Drug Treatment in Rheumatoid Arthritis and Its Predictors: A National, Multicenter, Retrospective Cohort.
Tavares R, Pope JE, Tremblay JL, Thorne C, Bykerk VP, Lazovskis J, Blocka KL, Bell MJ, Lacaille D, Hitchon CA, Fitzgerald AA, Fidler WK, Bookman AA, Henderson JM, Mosher DP, Sholter DE, Khraishi M, Haraoui B, Chen H, Li X, Laupacis A, Boire G, Tomlinson G, Bombardier C.
J Rheumatol. 2012 Nov;39(11):2088-2097. Epub 2012 Aug 15. PMID: 22896027

The Canadian Early Arthritis Cohort (CATCH): Patients with New-onset Synovitis Meeting the 2010 ACR/EULAR Classification Criteria But Not the 1987 ACR Classification Criteria Present with Less Severe Disease Activity.
Bykerk VP, Jamal S, Boire G, Hitchon CA, Haraoui B, Pope JE, Thorne JC, Sun Y, Keystone EC.
J Rheumatol. 2012 Nov;39(11):2071-80. doi: 10.3899/jrheum.120029. Epub 2012 Aug 15.  PMID: 22896026

Incidence and predictors of secondary fibromyalgia in an early arthritis cohort.
Lee YC, Lu B, Boire G, Haraoui BP, Hitchon CA, Pope JE, Thorne JC, Keystone EC, Solomon DH, Bykerk VP.
Ann Rheum Dis. 2013 Jun;72(6):949-54. doi: 10.1136/annrheumdis-2012-201506. Epub 2012 Jul 11 [Epub ahead of print] PMID: 22791744

Quality assurance study of the use of preventative therapies in glucocorticoid-induced osteoporosis in early inflammatory arthritis: results from the CATCH cohort.
McKeown E, Bykerk VP, De Leon F, Bonner A, Thorne C, Hitchon CA, Boire G, Haraoui B, Ferland DS, Keystone EC, Pope JE; on behalf of the CATCH Investigators.
Rheumatology (Oxford). 2012 Sep;51(9):1662-9. Epub 2012 Apr 25. [Epub ahead of print] PMID:22539481

Remission in early rheumatoid arthritis -- a comparison of new ACR/EULAR remission criteria to established criteria.
Kuriya B, Sun Y, Boire G, Haraoui B, Hitchon C, Pope JE, Thorne JC, Keystone EC, Bykerk VP; Canadian Early Arthritis Cohort Study.
J Rheumatol. 2012 Jun;39(6):1155-8. Epub 2012 Apr 15. PMID:22505708

Low prevalence of work disability in early inflammatory arthritis (EIA) and early rheumatoid arthritis at enrollment into a multi-site registry: results from the catch cohort.
Mussen L, Boyd T, Bykerk V, de Leon F, Li L, Boire G, Hitchon C, Haraoui B, Thorne JC, Pope J.
Rheumatol Int. 2013 Feb;33(2):457-65. doi: 10.1007/s00296-012-2407-3. Epub 2012 Mar 30. [Epub ahead of print] PMID:22461187

Safety and effectiveness of rituximab in patients with rheumatoid arthritis following an inadequate response to 1 prior tumor necrosis factor inhibitor: the RESET Trial.
Haraoui B, Bokarewa M, Kallmeyer I, Bykerk VP; RESET Investigators (Boire G).
J Rheumatol. 2011 Dec;38(12):2548-56. Epub 2011 Oct 1. PMID: 21965646

Early management of newly diagnosed rheumatoid arthritis by Canadian rheumatologists: a National, Multicenter, Retrospective cohort.
Tavares R, Pope JE, Tremblay JL, Thorne C, Bykerk VP, Lazovskis J, Blocka KL, Bell MJ, Lacaille D, Hitchon CA, Fitzgerald AA, Fidler WK, Bookman AA, Henderson JM, Mosher DP, Sholter DE, Khraishi M, Haraoui B, Chen H, Li X, Laupacis A, Boire G, Tomlinson G, Bombardier C.
J Rheumatol. 2011 Nov;38(11):2342-5. Epub 2011 Sep 1.  PMID: 21885485

A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.
Budarf ML, Goyette P, Boucher G, Lian J, Graham RR, Claudio JO, Hudson T, Gladman D, Clarke AE, Pope JE, Peschken C, Smith CD, Hanly J, Rich E, Boire G, Barr SG, Zummer M; GenES Investigators, Fortin PR, Wither J, Rioux JD.
Genes Immun. 2011 Jan;12(1):51-8. Epub 2010 Oct 21.  PMID: 20962850

The increased in vitro osteoclastogenesis in patients with rheumatoid arthritis is due to increased percentage of precursors and decreased apoptosis - The In Vitro Osteoclast Differentiation in Arthritis (IODA) study.
Durand M, Boire G, Komarova SV, Dixon SJ, Sims SM, Harrison RE, Nabavi N, Maria O, Manolson MF, Mizianty M, Kurgan L, de Brum-Fernandes AJ.
Bone. 2011 Mar 1;48(3):588-96. Epub 2010 Oct 17. PMID: 20959150

Care gap in patients with early inflammatory arthritis with a high fracture risk identified using FRAX(®).
Cheng CK, McDonald-Blumer H, Boire G, Pope JE, Haraoui B, Hitchon CA, Thorne C, Sun Y, Bykerk VP.
J Rheumatol. 2010 Nov;37(11):2221-5. Epub 2010 Aug17. PMID: 20716658

Occupational and environmental exposures and risk of systemic lupus erythematosus: silica, sunlight, solvents.
Cooper GS, Wither J, Bernatsky S, Claudio JO, Clarke A, Rioux JD; CaNIOS GenES Investigators, Fortin PR.
Rheumatology (Oxford). 2010 Nov;49(11):2172-80. Epub 2010 Jul 31. PMID: 20675707

Outcomes in recent-onset inflammatory polyarthritis differ according to initial titers, persistence over time, and specificity of the autoantibodies.
Guzian MC, Carrier N, Cossette P, de Brum-Fernandes AJ, Liang P, Ménard HA, Boire G.
Arthritis Care Res (Hoboken). 2010 Nov;62(11):1624-32. doi: 10.1002/acr.20288. Epub 2010Jul 8. PMID: 20617532

Canadian recommendations for use of methotrexate in patients with rheumatoid arthritis.
Katchamart W, Bourré-Tessier J, Donka T, Drouin J, Rohekar G, Bykerk VP, Haraoui B, Leclerq S, Mosher DP, Pope JE, Shojania K, Thomson J, Thorne JC, Bombardier C; Canadian 3e Initiative Consensus Group.
J Rheumatol. 2010 Jul;37(7):1422-30. Epub 2010 Jun 1. PMID: 20516029

Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort.
Oen K, Duffy CM, Tse SM, Ramsey S, Ellsworth J, Chédeville G, Chetaille AL, Saint-Cyr C, Cabral DA, Spiegel LR, Schneider R, Lang B, Huber AM, Dancey P, Silverman E, Rosenberg AM, Cameron B, Johnson N, Dorval J, Scuccimarri R, Campillo S, Petty RE, Duffy KN, Boire G, Haddad E, Houghton K, Laxer R, Turvey SE, Miettunen P, Gross K, Guzman J, Benseler S, Feldman BM, Espinosa V, Yeung RS, Tucker L.
Arthritis Care Res (Hoboken). 2010 Apr;62(4):527-36. PMID: 20391508

CD40-activated B cells from patients with systemic lupus erythematosus can be modulated by therapeutic immunoglobulins in vitro.
Néron S, Boire G, Dussault N, Racine C, de Brum-Fernandes AJ, Côté S, Jacques A.
Arch Immunol Ther Exp (Warsz). 2009 Nov-Dec;57(6):447-58. Epub 2009 Oct 29. PMID: 19866343

Predictors of early inactive disease in a juvenile idiopathic arthritis cohort: results of a Canadian multicenter, prospective inception cohort study.
Oen K, Tucker L, Huber AM, Miettunen P, Scuccimarri R, Campillo S, Cabral DA, Feldman BM, Tse S, Chédeville G, Spiegel L, Schneider R, Lang B, Ellsworth J, Ramsey S, Dancey P, Silverman E, Chetaille AL, Cameron B, Johnson N, Dorval J, Petty RE, Duffy KW, Boire G, Haddad E, Houghton K, Saint-Cyr C, Turvey SE, Benseler S, Cheang M, Yeung RS, Duffy CM.
Arthritis Rheum. 2009 Aug 15;61(8):1077-86. PMID: 19644903

The DERAA HLA-DR alleles in patients with early polyarthritis: protection against severe disease and lack of association with rheumatoid arthritis autoantibodies.
Carrier N, Cossette P, Daniel C, de Brum-Fernandes A, Liang P, Ménard HA, Boire G.
Arthritis Rheum. 2009 Mar;60(3):698-707. PMID: 19248090

Résumés

2009

Guzian MC, Carrier N, Cossette P, Daniel C, de Brum-Fernandes A, Liang P, Ménard HA, Boire G. Baseline predictors of RA-associated antibodies seroconversion and seroreversion over 30 months in patients with early inflammatory polyarthritis (EPA). Poster presentation at the Canadian Rheumatology Association 64th Annual Meeting and Scientific Program, Kananaskis, Alberta, February 18-21, 2009. The Journal of Rheumatology2009;36 (11):2608;doi:10.3899/jrheum.090763

Guzian MC, Carrier N, Cossette P, de Brum-Fernandes A, Liang P, Ménard HA, Boire G.Outcomes At 30 Months In Patients With Recent-Onset Polyarthritis (EPA): Does Stability Of Rheumatoid Arthritis (RA)-Associated Antibodies Have An Impact?Poster presentation at the Canadian Rheumatology Association 64th Annual Meeting and Scientific Program, Kananaskis, Alberta, February 18-21, 2009. The Journal of Rheumatology2009;36(11):2584; doi:10.3899/jrheum.090763

Akhavan PS, Neville C, Su J, Kassis J, Solymoss S, Pineau C, Peschken C, Pope J, Boire G, Rauch J, Fortin PR. Vascular Events in Systemic Lupus Erythematosus (SLE): Evaluation of Thrombophilic Factors in a Multicentre Inception Cohort (Thrombofil).Poster presentation at the Canadian Rheumatology Association 64th Annual Meeting and Scientific Program, Kananaskis, Alberta, February 18-21, 2009.The Journal of Rheumatology2009;36 (11):2604;doi:10.3899/jrheum.090763.

Bykerk VP, Boire G, Haraoui B, Pope J, Hitchon C, Jamal S, Cheng CK, Thorne C, Mosher D, Ahluwalia V, Larche M, Bensen B, Khraishi M, Zummer M, Nair B, Bell M, Cividino A, Klinkhoff A. Successful Clinical Outcomes in Canadian Early Inflammatory Arthritis Patients: Data from the CATCH Study.Poster presentation at the Canadian Rheumatology Association 64th Annual Meeting and Scientific Program, Kananaskis, Alberta, February 18-21, 2009.The Journal of Rheumatology2009;36 (11):2591;doi:10.3899/jrheum.090763.

Bykerk VP, Cheng CK, Boire G, Pope JE, Haraoui B, Hitchon CA., et al. Care Gap in Early Inflammatory Arthritis Patients with a High Fracture Risk Identified Using the FRAX Tool[abstract]. Arthritis Rheum2009;60 Suppl 10 :1193. DOI: 10.1002/art.26267

Petre MA, Cheng CK, Boire G, Pope JE, Haraoui B, Hitchon CA., et al. Prognostic Value of Patient History, Radiography and Serology On Poor Outcomes in Undifferentiated Inflammatory Arthritis Patients[abstract]. Arthritis Rheum2009;60 Suppl 10 :1191.  DOI: 10.1002/art.26265

Katchamart W, Boire G, Pope JE, Haraoui B, Hitchon CA, Jamal S, et al. The Clinical Course, Outcomes, and Treatment of Early Inflammatory Arthritis: Results From CATCH (Canadian Early Arthritis Cohort) [abstract]. Arthritis Rheum 2009;60 Suppl 10 :369.  DOI: 10.1002/art.25452

Boire G, Beaulieu M, Lambert D, Cabana F. The OPTIMUS intervention: Primary Care Practitioners treating osteoporosis in up to 64% of patients with fragility fracture. J Bone Miner Res 2009;24 (Suppl 1). Available at http://www.asbmr.org/Meetings/AnnualMeeting/AbstractDetail.aspx?aid=e1ed0ab6-2df2-4277-a9dd-f45cd94400e4. Accessed September 25, 2009.

2010

Guzian MC, Carrier N, Cossette P, Boire G. Categorizing intensity of DMARD treatments in longitudinal cohorts. Poster presentation at the Canadian Rheumatology Association 65th Annual Meeting and Scientific Program, Québec City, Québec, February 3-6, 2010.The Journal of Rheumatology2010;37(6) :1287;doi.10.3899/jrheum.100360

McKeown E, Pope J, De Leon F, ThorneC, Hitchon C, Boire G, BykerkV. Quality Assurance Study of the Use of Preventative Therapies inGlucocorticoid Induced Osteoporosis (GIOP) in Early InflammatoryArthritis: Results from the CATCH Cohort. Poster presentation at the Canadian Rheumatology Association 65th Annual Meeting and Scientific Program, Québec City, Québec, February 3-6, 2010.The Journal of Rheumatology2010;37(6) :1299;doi.10.3899/jrheum.100360

Cabana F, Lambert D, Beaulieu M, Boire G. Priming Primary Care Practitioners to treat Osteoporosis in their patients with a fragility fracture. Poster presentation at the Canadian Rheumatology Association 65th Annual Meeting and Scientific Program, Québec City, Québec, February 3-6, 2010.The Journal of Rheumatology2010;37(6) :1313;doi.10.3899/jrheum.100360

Hitchon C, Boire G, Haraoui B, Jamal S, Pope J, Thorne C, Mosher D, Bensen W, Zummer M, KraishiM, Nair B, Klinkhoff A, CividinoA, BykerkV. Patient Self Reported Health Related Quality of Life Improves withEffective Treatment in Early Inflammatory Arthritis (EIA).Poster presentation at the Canadian Rheumatology Association 65th Annual Meeting and Scientific Program, Québec City, Québec, February 3-6, 2010.The Journal of Rheumatology2010;37(6) :1329;doi.10.3899/jrheum.100360

Petre M, Cheng C, BoireG, Pope J, Haraoui B, Hitchon C, Jamal S, Thorne C, BykerkV. Prognostic Value of Patient History, Radiography and Serology on PoorOutcomes in Undifferentiated Inflammatory Arthritis Patients.Poster presentation at the Canadian Rheumatology Association 65th Annual Meeting and Scientific Program, Québec City, Québec, February 3-6, 2010.The Journal of Rheumatology2010;37(6) :1341;doi.10.3899/jrheum.100360

Fernandes A, Boire G, Dixon J, Durand M, Harrison R, Komarova S, Kurgan L, Manolson M, Maria O, Mizianty M, Rak R, Roy M, Sims S, Trebec-Reynolds D.The In Vitro Osteoclast Differentiation in Arthritis (IODA) Project: Osteoclastogenesis as a Marker of Presence and Activity of Disease in Arthritis.Poster presentation at the Canadian Rheumatology Association 65th Annual Meeting and Scientific Program, Québec City, Québec, February 3-6, 2010.The Journal of Rheumatology2010;37(6) :1349;doi.10.3899/jrheum.100360

Kuriya B, Haraoui B,Boire G, Hitchon CA, Pope JE, Thorne JC, et al. Age, Sex, RF Antibodies, Baseline HAQ and DAS28 ScoreBut Not the Type of Initial TreatmentAre Predictive of Clinical Remission at 1 Year in Early Inflammatory Arthritis. [abstract]. Arthritis Rheum 2010;62 Suppl 10 :1737.  DOI: 10.1002/art.29502

Bykerk VP, Boire G, Haraoui B, Hitchon CA, Ferland D, Thorne C, et al. DAS28 Level at Baseline Best Predicts Which Patients with New Onset Inflammatory Arthritis Will Ultimately Require Biologic Therapy. [abstract]. Arthritis Rheum 2010;62 Suppl 10 :300.  DOI: 10.1002/art.28069

Akhavan P, Bykerk VP, Sun Y, Hochman J, Pope JE, Pope JE, et al (Boire G). Disease Activity in Patients with Early Rheumatoid Arthritis Receiving Stable Conventional DMARDs Significantly Influences the Timing of Achieving a Low Disease State and Remission at 3 Versus 6 Months. [abstract]. Arthritis Rheum 2010;62 Suppl 10 :306.  DOI: 10.1002/art.28075

McKeown E, Bykerk VP, Deleon F, Thorne JC, Hitchon CA, Boire G, et al. Quality Assurance Study of the Use of Preventative Therapies in Glucocorticord Induced Osteoporosis (GIOP) in Early Inflammatory Arthritis (EIA): Results from the CATCH Cohort. [abstract]. Arthritis Rheum 2010;62 Suppl 10 :978.  DOI: 10.1002/art.28745

Bykerk VP, Boire GB, Haraoui B, Hitchon CA, Keystone EC, Thorne JC, et al. The Revised 2010 ACR/EULAR Diagnostic Criteria for Rheumatoid Arthritis Identify Many More Patients Who Are Eligible for Treatment and for Clinical Trials. [abstract]. Arthritis Rheum 2010;62 Suppl 10 :659
DOI: 10.1002/art.28427

Akhavan P, Bykerk VP, Sun Y, Hochman J, Pope JE, Hitchon CA, et al (Boire G). Three Months of Therapy with DMARDs Is an Inadequate Period of Time To Alter the Treatment in Patients with Early Rheumatoid Arthritis When Treating to a Target of Low Disease State or Remission. Results from Canadian Early ArThritis CoHort (CATCH).[abstract]. Arthritis Rheum 2010;62 Suppl 10 :343DOI: 10.1002/art.28112

Boire G, Cabana F, Mikhail S, Lambert D. Who is Not Ttreated Following the Implementation of OPTIMUS, a Successful Initiative to Treat Osteoporosis Following a Fragility Fracture. JBMR 2010. Accepted as a poster presention at the ASBMR Annual Meeting in Toronto (Canada).

2011

Cao Y, Bonner A, Barra L, Thorne C, Haraoui B, Boire G, Hitchon C, Le Riche N, Thompson A, Keystone E, Bykerk V, Pope J.Response to Second-Line DMARDs and to Biologics in Seropositive vs. Seronegative Patients in Early and Late RA: Results from the CATCH Cohort of Early RA and a Large Established RA Database. The Journal of Rheumatology2011;38(6):1134; doi:10.3899/jrheum.110506

Bykerk V, Haraoui B, Boire G, Hitchon C, Keystone E, Thorne C, Ferland D, Pope J, CATCH Investigators of Canada.Validation of the 2010 Criteria to Diagnose RA in a Canadian Multicenter Cohort Of Patients with New Onset Inflammatory Arthritis. The Journal of Rheumatology2011;38(6):1140; doi:10.3899/jrheum.110506

Barnabe C, Pope J, Boire G, Hitchon C, Haraoui B, Thorne C, Keystone E, Ferland D, Bykerk V. Patient Sex Does Not Influence Pain Levels in Early Inflammatory Arthritis.The Journal of Rheumatology2011;38(6):1149; doi:10.3899/jrheum.110506

Boyd T, Bykerk V, Haraoui B, Thorne C, Hitchon C, Boire G, Pope J. The Relationship between Function and Disease Activity as Measured by HAQ DI and DAS Varies by Rheumatoid Factor Status in ERA. Results from the CATCH cohort. The Journal of Rheumatology2011;38(6):1167; doi:10.3899/jrheum.110506

Beaulieu MC, Gosselin S, Gaboury I, Vanasse A, Cabana F, Boire G. Treating Osteoporosis After A Fragility Fracture: The Family Physician As The Hub. The Journal of Rheumatology2011;38(6):1171; doi:10.3899/jrheum.110506

Hitchon C, Dooley J, Boire G, Haraoui B, Pope J, Thorne C, Ferland D, Bykerk V, Network of Early Arthritis Researchers. Comorbidity is Commonly Reported in Early Inflammatory Arthritis. The Journal of Rheumatology2011;38(6):1184; doi:10.3899/jrheum.110506

Bykerk VP, Rohekar G, Sun Y,Boire G, Haraoui B, Hitchon C, Ferland D, Thorne C, Keystone EC, Pope JE, CATCH Investigators. High Disease Activity, Younger Age and Longer Symptom Duration Predict Which Patients With Early RA Will Receive Biological Therapy.Ann Rheum Dis2011;70(Suppl3):727

Bernard M, de Brum-Fernandes AJ, Liang P, Cossette P, Ménard HA, Masetto A,Boire G.  The Different Definitions of Remission in Early Inflammatory Arthritis Are Not Interchangeable.Ann Rheum Dis2011;70(Suppl3):76

Lee YC, Solomon DH,Boire G, Haraoui B, Hitchon CA, Pope JE, Thorne JC, Keystone EC, Ferland DS, Bykerk VP, CATCH Investigators. The Prevalence of Secondary Fibromyalgia in an Early Inflammatory Arthritis Cohort Increases With Time But The Diagnosis May Not Be Permanent. Ann Rheum Dis2011;70(Suppl3):158

Barra LJ, Bykerk V, Pope J, Haraoui P, Hitchon C, Thorne C, Keystone E, Ferland D, Boire G. Anti-Cyclic Citrullinated Peptide Antibodies and Rheumatoid Factor Stability in Early Inflammatory Arthritis. Ann Rheum Dis2011;70(Suppl3):641

Bernard M, de Brum-Fernandes AJ, Cossette P, Liang P, Masetto A, Ménard HA, Boire G. The Long Term Consequences of Adopting Less Stringent Definitions for Remission When Treating To Target. Ann Rheum Dis2011;70(Suppl3):645

Akhavan P, Bykerk V, Sun Y,Boire G, Haraoui B, Pope J, Thorne C, Ferland D, Hitchon C, Weber D, Keystone E. Disease Activity State at 3 Months is a Better Predictor of Outcome at 6 Months Than Response to Treatment (DAS28 Change) in a Cohort of Early Rheumatoid.Ann Rheum Dis2011;70(Suppl3):649

Akhavan P, Bykerk V, Sun Y, Boire G, Thorne C, Pope J, Hitchon C, Haraoui B, Ferland D, Keystone E, CATCH Investigators. A Substantial Proportion of Patients Failing To Achieve DAS28 or ACR20 Response at 12 Weeks of DMARD Therapy Exhibit Improvement in Core Set Measures. Results From an Early Arthritis Cohort.Ann Rheum Dis2011;70(Suppl3):649

Kuriya B, Sun Y,Boire G, Haraoui B, Hitchon C, Pope J, Thorne C, Ferland D, Keystone E, Bykerk V, CATCH Investigators. Prevalence of Remission in Early RA – A Comparison of New Remission Criteria to Established Criteria.Ann Rheum Dis2011;70(Suppl3):654

Cao Y, Bonner A, Barra L, Thorne JC, Haraoui B,Boire G, Hitchon C, LeRiche N, Bell D, Thompson A, Keystone E, Bykerk V, Pope J. Response to Second-Line DMARDS and to TNFIs in Seropositive vs. Seronegative Patients in Early and Late RA. Results From The CATCH Cohort of Early RA and a Large Established RA Database. Ann Rheum Dis2011;70(Suppl3):257

Akhavan P, Sun Y, Keystone E,Boire G, Haraoui B, Pope J, Thorne C, Ferland D, Bykerk V, CATCH Investigators. Glucocorticoid Use in Patients With Early Rheumatoid Arthritis. Results From an Early Arthritis Cohort.Ann Rheum Dis2011;70(Suppl3):278

Hitchon C, Boire G, Lloyd A, Centola M, Kay R, El-Gabalawy H. Clinical Outcome in Early Undifferentiated Arthritis is Best Predicted By a Combination of Baseline Clinical Features and Serum Biomarkers. Ann Rheum Dis2011;70(Suppl3):284

Boyd T, Bykerk V, Boire G, Hitchon C, Thorne JC, Keystone E, Ferland D, Pope J. The Relationship Between Function And Disease Activity as Measured by HAQ DI and DAS Varies by Rheumatoid Factor Status in ERA. Results From The CATCH Cohort. Ann Rheum Dis2011;70(Suppl3):294

2012

Cabana F, Beaulieu M, Lambert D, Côté PY, Vaillancourt M, Beaulieu MC, Roux S, Boire G. Incidence of subsequent fractures according to age and site of initial non-vertebral fractures: the first 3 years of the OPTIMUS initiative. Accepted as a poster presention at the ASBMR Annual Meeting in San Diego USA. J Bone Miner Res 2011; 26 (Suppl 1). Available at http://www.asbmr.org/Meetings/AnnualMeeting/AbstractDetail.aspx?aid=facc29ad-634a-475c-a146-127c1e981a35. Accessed September 10, 2012.

Bykerk VP, Bartlett SJ, Choy E,Boire G, Hitchon C, Pope J, Thorne C, Haraoui B, Keystone E, Bingham CO III, on behalf of OMERACT RA Flare Group and CATCH.
An evaluation of flare in patients with early rheumatoid arthritis using the OMERACT preliminary flare questionnaire.
Ann Rheum Dis 2012;71(Suppl3):180

Harris J, Bykerk V, Hitchon C, Keystone E, Thorne C, Boire G, Haraoui BP, Hazelwood G, Bonner A, Pope J, and CATCH ERA Cohort. Can we improve outcomes in early rheumatoid arthritis (ERA) by determining best practices? An analysis of the Canadian ERA cohort (CATCH). Ann Rheum Dis 2012;71(Suppl3):336

Akhavan P, BykerkV, Sun Y, Choi M, Pope J, Hitchon C, Boire G, Haraoui B, Thorne C, Tin D, Keystone E, and CATCH Investigators. Discrepancy between Patient and Physician Global Assessments in Early Rheumatoid Arthritis (RA) – the need for swollen joint evaluation. Ann Rheum Dis 2012;71(Suppl3):340

PyneL, Bykerk V, Hitchon C, Keystone E, Thorne C, Boire G, Haraoui BP, Bonner A, Pope J, and CATCH. DAS does not predict increasing treatment in Early Rheumatoid Arthritis (ERA): Results from the CATCH study. Ann Rheum Dis 2012;71(Suppl3):504

BykerkVP, Bartlett SJ, Choy E, Boire G, Hitchon C, Pope J, Thorne C, Haraoui B, Keystone E, Bingham CO III, on behalf of Omeract RA Flare Group and CATCH. Early RA patients reporting a flare identify more tender than swollen joints. Ann Rheum Dis 2012;71(Suppl3):509

Cabana F,Roux S, Beaulieu MC, Beaulieu M, Boire G. Incidence of subsequent fractures according to site of initial non-vertebral fractures and treatment status: the first 3 years of the OPTIMUS initiative. Ann Rheum Dis 2012;71(Suppl3):589

Beaulieu MC, Cabana F, Beaulieu M, Roux S, Boire G. Management of fragility fractures: impact of the OPTIMUS initiative on family physicians. Ann Rheum Dis 2012;71(Suppl3):596

AprilPM, Roux S, Beaulieu MC, Beaulieu M, Cabana F, Boire G. Estimated FRAX® 10-year fracture risk at the time of incident fracture and upon refracture: results from the OPTIMUS initiative. Accepted as a Plenary Poster Presentation. ASBMR Annual meeting, Minneapolis MN, October 12 2012.

Masetto A, Fernandes AJ, Liang P, Cossette P, Boire G. 2010 ACR/EULAR Rheumatoid Arthritis Classification Criteria Predicts Radiogical, but Not Clinical Outcomes At 18 Months Into Disease in a Canadian Early Arthritis Cohort. Accepted as an Oral Concurrent Session at the 2012 ACR/ARHP Annual Meeting, to be held in Washington, D.C., November 9-14, 2012.

Wong LE, Xiong J, Boire G, Haraoui B, Pope JE, Thorne JC, Hitchon CA, Tin D, Keystone EC, Bykerk VP, CATCH Investigators.
Effect of Duration in Menopause on Disease Presentation in Early Rheumatoid Arthritis (RA).  EULAR 2013.

Discrepancy Between Patient and Physician Global Assessments Over Time in Early Rheumatoid Arthritis.  Poster.  Canadian Rheumatology Association 2013.

Arnold M, Bykerk V, Boire G, Haraoui B, Hitchon C, Thorne C, Keystone E, Pope J.
Are there differences betgween young and older onset early rheumatoid arthritis (RA) and does this impact outcomes?  An analysis from the CATCH cohort.  Poster. Canadian Rheumatology Association 2013.

Hazlewood G, Thorne C, Pope J, Boire G, Haraoui B, Hitchon C, Keystone E, Tin D, Bykerk V, CATCH Investigators.
The comparative effectiveness of oral methotrexate versus subcutaneous methotrexate for the initial treatment of early rheumatoid arthritis.  Poster.  EULAR 2013.

Kuriya B, Xiong J, Boire G, Haraoui B, Hitchon C, Pope J, Thorne C, Keystone E, Tin D, Bykerk V.
Predictors of sustained clinical remission in early rheumatoid arthritis-results from the CATCH cohort. Poster.  Canadian Rheumatology Association 2013.

Bartlett SJ, Bingham CO, Choy E, Xiong J, Boire G, Haraoui B, Pope JE, Thorne JC, Hitchon CA, Tin D, Keystone EC, Bykerk VP, CATCH Investigators, OMERACT RA Flare Groupe.
Establishing the content validity of OMERACT preliminary flare questions (PFQ) for detecting and measuring disease exacerbations in rheumatoid arthritis.  Poster.  EULAR 2013.

Hazleweed G, Thorne C, Pope J, Boire G, Haraoui B, Hitchon C, Keystone E, Tin D, CATCH Investigators, Bykerk V.
The comparative effectiveness of oral methotrexate versus subcutaneous methotrexate for the treatment of early rheumatoid arthritis.  Poster.  Canadian Rheumatology Association 2013.

2013

Lauren Wong, Wei-Ti Huang, Juan Xiong, Gilles Boire, Boulos Haraoui, Janet E. Pope, J. Carter Thorne, Carol A. Hitchon, Diane Tin, Edward Keystone and Vivian P. Bykerk.
Effect Of Age At Menopause In Women With Early Rheumatoid Arthritis.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S162, 374.

Karen Visser, Susan J. Bartlett, Clifton O. Bingham III, Ernest Choy, Daming Lin, Juan Xiong, Gilles Boire, Boulos Haraoui, Carol A. Hitchon, Edward Keystone, Janet E. Pope, J. Carter Thorne, Diane Tin and Vivian P. Bykerk.
Changes In Patient-Reported Joint Counts and Composite Indices Can Identify Flare Of Disease Activity In Recent Onset Rheumatoid Arthritis.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S1230, 2869.

Karen Visser, Janet E. Pope, Ernest Choy, Clifton O Bingham III, Susan J. Bartlett, Gilles Boire, Carol A. Hitchon, J. Carter Thorne, Boulos Haraoui, Diane Tin, Edward Keystone and Vivian P.
Reliability and Validity Of Patient-Reported Joint Counts and Determinants Of Disagreement With The Physician In Recent Onset Rheumatoid Arthritis.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S1229, 2868.

Jeffrey R. Curtis, Shuo Yang, Lang Chen, Janet E. Pope, Edward C. Keystone, Boulos Haraoui, Gilles Boire, J. Carter Thorne, Diane Tin, Carol A. Hitchon, Clifton O. Bingham III and Vivian P. Bykerk.
Determining The Absolute Change In The Clinical Disease Activity Index (CDAI) To Define a Minimally Important Difference.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S1228, 2866.

Mohammed Omair, Edward C. Keystone, Juan Xiong, Gilles Boire, Janet E. Pope, J. Carter Thorne, Carol A. Hitchon, Boulos Haraoui, Diane Tin, Deborah Weber, Vivian P. Bykerk and Pooneh Akhavan.
Are SDAI50 and DAS28 Response Measures Comparable In Early Rheumatoid Arthritis Patients?
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S978, 2296.

Grace Yang, Vivian P. Bykerk, J. Carter Thorne, Gilles Boire, Diane Tin, Carol A. Hitchon, Edward Keystone, Boulos Haraoui and Janet E. Pope.
Does Socioeconomic Status Affect Outcomes In Early Rheumatoid Arthritis? Data From An Inception Cohort.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S969, 2276.

Vivian P. Bykerk, Karen Visser, Ernest Choy, Clifton O. Bingham III, Daming Lin, Juan Xiong, Gilles Boire, Boulos Haraoui, Carol A. Hitchon, Janet E. Pope, J. Carter Thorne, Diane Tin, Edward C. Keystone, Susan J. Bartlett, - CATCH Investigators and - OMERACT Flare Working Group.
Responsiveness Of The Outcomes Measures In Rheumatology Clinical Trials Initiative’s Preliminary Flare Questions To Detect Flares Within Patients In The Canadian Early Arthritis Cohort. 
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S968, 2275.

Susan J. Bartlett, Clifton O. Bingham III, Ernest Choy, Juan Xiong, Gilles Boire, Boulos Haraoui, Janet E. Pope, J. Carter Thorne, Carol A. Hitchon, Diane Tin, Edward C. Keystone and Vivian P. Bykerk.
Assessing Significant Flares In Rheumatoid Arthritis: Validity Of The Outcome Measures In Rheumatology Preliminary Flare Questions In The Canadian Early Arthritis Cohort.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S953, 2241.

Pooneh Akhavan, Bindee Kuriya, Edward C. Keystone, Juan Xiong, Janet E. Pope, Gilles Boire, Diane Tin, Boulos Haraoui, Carol A. Hitchon and Vivian P. Bykerk.
Reaching The Target Of Low Disease Activity At 6 Months Predicts Better Long-Term Functional Outcome In Patients With Early Rheumatoid Arthritis.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S762, 1791.

Walter P. Maksymowych, Dirkjan van Schaardenburg, Desire van der Heijde, Robert Landewe, Gilles Boire, Maarten Boers, Vivian P. Bykerk, Edward C. Keystone, Katherine A. Siminovitch, Mairead Murphy and Anthony Marotta.
91% Of Early RA Patients Are Positive For Serum 14–3–3_ Or Its Auto-Antibodies.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S760, 1786.

Sonia Jean, Philippe Gamache, Marie Hudson, Louis Bessette, Paul R. Fortin, Gilles Boire and Sasha Bernatsky.
Trends In Incidence and Mortality In Rheumatoid Arthritis and Systemic Autoimmune Rheumatic Diseases In Quebec, Canada: A Population-Based Study.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S746, 1756.

Glen S. Hazlewood, J. Carter Thorne, Janet E. Pope, Juan Xiong, Gilles Boire, Boulos Haraoui, Carol A. Hitchon, Edward C. Keystone, Diane Tin and Vivian P. Bykerk. 
Subcutaneous Delivery Of Methotrexate Is Associated With Improved Treatment Survival Compared To Oral Administration For The Initial Treatment Of Patients With Early Rheumatoid Arthritis.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S627, 1475.

Jonathan D. Jones, B. JoNell Hamilton, Greg Challener, Artur Fernandes, Pierre Cossette, Patrick Liang, Ariel Masetto, HA Menard, Nathalie Carrier, Gilles Boire and William Rigby.
CXCL13 Is Elevated In Early and In Established Seropositive Rheumatoid Arthritis and Correlates With Rheumatoid Factor Levels.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S589, 1395.

Michael Arnold, Vivian P. Bykerk, Gilles Boire, Boulos Haraoui, Carol A. Hitchon, J. Carter Thorne, Edward Keystone and Janet E. Pope.
Are There Differences Between Young and Older Onset Early Rheumatoid Arthritis and Does This Impact Outcomes? An Analysis From The Canadian Early Arthritis Cohort.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S567, 1343.

Tommy Choy, Vivian P. Bykerk, Gilles Boire, Boulos Haraoui, Carol A. Hitchon, J. Carter Thorne, Edward . Keystone and Janet E. Pope.
Physician Global Assessment At Three Months Is Strongly Predictive Of Remission At 12 Months In Early Rheumatoid Arthritis. Results From The Canadian Early Arthritis Cohort. 
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S562, 1329.

Mihaela Popescu, Edith Villeneuve, Boulos Haraoui, Gilles Boire, Carol A. Hitchon, Edward C. Keystone, Janet E. Pope, J. Carter Thorne, Diane Tin and Vivian P. Bykerk.
Prevalence and Impact Of Soft Tissue Manifestations In Early Inflammatory Arthritis: Results From The Canadian Early Arthritis Cohort. 
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S557, 1318.

Lillian J. Barra, Janet E. Pope, Boulos Haraoui, Carol A. Hitchon, J. Carter Thorne, Edward C. Keystone, Diane Tin, Gilles Boire and Vivian P. Bykerk.
Prognosis Of Seronegative Patients In a Large Prospective Cohort Of Patients With Early Inflammatory Arthritis.
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S553, 1309.

Bindee Kuriya, Juan Xiong, Gilles Boire, Boulos Haraoui, Carol A. Hitchon, Janet E. Pope, J. Carter Thorne, Diane Tin, Edward C. Keystone, Cheryl Barnabe, Pooneh Akhavan and Vivian P. Bykerk.
Do Sustained Clinical Remission and Sustained Low Disease Activity Equally Predict Functional Status In Early Rheumatoid Arthritis?
ACR Meeting, October 25-30, 2013 – San Diego, California.  Arthritis & Rheumatism 65;S10:S552, 1306.

Deborah M. Levy, Shirley ML Tse, Elizabeth Stringer, Jaime Guzman, Roberta A. Berard, Karen Watanabe Duffy, Dax Rumsey, Mercedes O. Chan, Rosie Scuccimarri, Adam M. Huber, Lori B. Tucker, Rae SM Yeung, Ciaran M. Duffy, Kiem Oen and The ReACCh Out Investigators (Gilles Boire).
The Research In Arthritis In Canadian Children Emphasizing Outcomes (ReACCh Out) Cohort: Are We Achieving Clinically Important Outcomes?
Arthritis & Rheumatism 65;S10:S1194, 2790.

M. Omair, P. Akhavan, E. C. Keystone, J. Xiong, G. Boire, J. E. Pope, J. C. Thorne, C. A. Hitchon, B. Haraoui, D. Tin, D. A. Weber, V. P. Bykerk, CATCH Investigators.
Relationship Between DAS28 1.2 and SDAI50 Responses in Rheumatology Arthritis. 
EULAR June 12-15, 2013 – Madrid, Spain.  Ann Rheum Dis 2013;72(Suppl3):1024

M. Arnold, V. P. Bykerk, B. P. Haraoui, G. Boire, C. Hitchon, C. Thorne, E. Keystone, J. E. Pope.
Are there differences Between Young and Older Onset Early Rheumatoid arthritis (RA) and Does this Impact Outcomes? An Analysis from the CATCH Cohort.  EULAR June 12-15, 2013 – Madrid, Spain. Ann Rheum Dis 2013;72(Suppl 3):384

T. Choy, V. P. Bykerk, B. P. Haraoui, G. Boire, C. Hitchon, C. Thorne, E. Keystone, J. E. Pope.
Physician Global Assessment at three months is strongly Predicitve of Disease Activity at 12 Months in Early Rheumatoid Arthritis. Results from the CATCH Cohort.
EULAR June 12-15, 2013 – Madrid, Spain. Ann Rheum Dis 2013;72(Suppl 3):384

S. J. Bartlett, C. O. Bingham, E. Choy, J. Xiong, G. Boire, B. Haraoui, J. E. Pope, J. C. Thorne, C. A. Hitchon, D. Tin, E. C. Keystone, V. P. Bykerk, CATCH Investigators and OMERACT RA Flare Group.
Establishing the Content validity of omeract preliminary... 
EULAR June 12-15, 2013 – Madrid, Spain. Ann Rheum Dis 2013;72(Suppl 3):585

L. E. Wong, J. Xiong, G. Boire, B. Haraoui, J. E. Pope, J. C. Thorne, C. A. Hitchon, D. Tin, E. C. Keystone, V. P. Bykerk on behalf of CATCH Investigators.
Effect of duration in menopause on disease presentation. 
EULAR June 12-15, 2013 – Madrid, Spain.  Ann Rheum Dis 2013;72(Suppl 3):590

V. P. Bykerk, J. E. Pope, J. Xiong, G. Boire, B. Haraoui, J. C. Thorne, C. A. Hitchon, D. Tin, E. C. Keystone, on behalf of CATCH investigators.
Comparison of DAS28 using ESR and CRP in an Early Rheumatoid Arthritis Cohort.
EULAR June 12-15, 2013 – Madrid, Spain.  Ann Rheum Dis 2013;72(Suppl 3):590

G. Hazlewood, C. Thorne, J. Pope, G. Boire, B. Haraoui, C. Hitchon, E. Keystone, D. Tin, V. Bykerk, CATCH Investigators.
The comparative effectiveness of oral methotrexate.  EULAR June 12-15, 2013 – Madrid, Spain. 
Ann Rheum Dis 2013;72(Suppl 3):246

P.-M. April, F. Cabana, M.-C. Beaulieu, M. Beaulieu, S. Roux, G. Boire.
Up to half of first fragility fractures (FF), and a third of recurrent FF, occur in patients with low or moderate estimated Frax® 10-year fracture risk: results from the optimus initiative. 
EULAR June 12-15, 2013 – Madrid, Spain Ann Rheum Dis 2013; 72(Suppl 3):294.

Masetto A, Fernandes A, Liang P, Cossette P,Boire G.
2010 ACR/EULAR Rheumatoid Arthritis Classification Criteria Predicts Radiogical, but Not Clinical Outcomes at 18 Months into Disease in a Canadian Early Arthritis Cohort.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario.
J Rheumatol 40(6):P951, POD6

Bernatsky S, Dekis A, Boire G, Bessette L, Fortin P, Hudson M, Pineau C, Clarke A, Jean S, Chetaille AL, Ehrmann Feldman D, Belisle P, Bergeron L, Joseph L.
Rheumatoid Arthritis Prevalence Across Regions in Quebec
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario.
J Rheumatol 40(6):P955, POS3

Glen Hazlewood ( Calgary); Carter Thorne (Southlake Regional Health Care, The Arthritis Program, Newmarket); Janet Pope (University of Western Ontario, London); Gilles Boire (Université de Sherbrooke, Sherbrooke); Boulos Haraoui (University of Montreal, Montreal); Carol Hitchon (University of Manitoba, Winnipeg); Edward Keystone (University of Toronto, Toronto); Diane Tin (Southlake Regional Health Centre, Newmarket); all CATCH investigators (U of T, Toronto); Vivian Bykerk (Mount Sinai Hospital, Toronto).
The Comparative Effectiveness of Oral Methotrexate versus Subcutaneous Methotrexate for the Treatment of Early Rheumatoid Arthritis.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario. J Rheumatol 40(6):P971, POS45.

Tommy Choy (London); Vivian Bykerk (Mount Sinai Hospital, Toronto); Gilles Boire (Université de Sherbrooke, Sherbrooke); Boulos Haraoui (University of Montreal, Montreal); Carol Hitchon (University of Manitoba, Winnipeg); Carter Thorne (Southlake Regional Health Care, The Arthritis Program, Newmarket); Edward Keystone (University of Toronto, Toronto); Janet Pope (University of Western Ontario, London).
Physician Global Assessment at Three Months is Strongly Predictive of Disease Activity at 12 Months in Early Rheumatoid Arthritis. Results from the CATCH Cohort.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario. J Rheumatol 40(6):972, POS51.

Bindee Kuriya (University of Toronto, Toronto); Juan Xiong (The Rebecca MacDonald Center for Arthritis and Autoimmunity, Toronto); Gilles Boire (Université de Sherbrooke, Sherbrooke); Boulos Haraoui (University of Montreal, Montreal); Carol Hitchon (University of Manitoba, Winnipeg); Janet Pope (University of Western Ontario, London); Carter Thorne (Southlake Regional Health Care, The Arthritis Program, Newmarket); Edward Keystone (University of Toronto, Toronto); Diane Tin (Southlake Regional Health Centre, Newmarket); Vivian Bykerk (Mount Sinai Hospital, Toronto).
Predictors of Sustained Clincial Remission in Early Rheumatoid Arthritis- Results from the CATCH Cohort.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario.  J Rheumatol 40(6):987, POS94.

Carol Hitchon (University of Manitoba, Winnipeg); Gilles Boire (Université de Sherbrooke, Sherbrooke); Boulos Haraoui (University of Montreal, Montreal); Edward Keystone (University of Toronto, Toronto); Janet Pope (University of Western Ontario, London); Carter Thorne (Southlake Regional Health Care, The Arthritis Program, Newmarket); Vivian Bykerk (Mount Sinai Hospital, Toronto); all CATCH investigators (U of T, Toronto).
Self Reported Comorbidity is Common in Early Inflammatory Arthritis and Associated with Poorer Function and Quality of Life and Greater Disease Activity: Results from the Canadian Early Arthritis Cohort.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario. J Rheumatol 40(6):P998, POS123.

Michael Arnold (London); Vivian Bykerk (Mount Sinai Hospital, Toronto); Gilles Boire (Université de Sherbrooke, Sherbrooke); Boulos Haraoui (University of Montreal, Montreal); Carol Hitchon (University of Manitoba, Winnipeg); Carter Thorne (Southlake Regional Health Care, The Arthritis Program, Newmarket); Edward Keystone (University of Toronto, Toronto); Janet Pope (University of Western Ontario, London).
Are there Differences between Young and Older Onset Early Rheumatoid Arthritis (RA) and does this Impact Outcomes? An Analysis from the CATCH Cohort.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario. J Rheumatol 40(6):P1004, POS140.

Pierre-Marc April (Universite de Sherbrooke, Sherbrooke); Francois Cabana (Centre hospitalier universitaire de Sherbrooke, Sherbrooke); Sophie Roux (Universite de Sherbrooke, Sherbrooke); Marie-Claude Beaulieu (Universite de Sherbrooke, Sherbrooke); Michele Beaulieu (Merck Frosst Canada, Kirkland); Gilles Boire (Universite de Sherbrooke, Sherbrooke).
Limitations of Estimated FRAX® 10-Year Fracture Risk at the Time of Incident Fracture and Upon Refracture: Results from the OPTIMUS Initiative.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario. J Rheumatol 40(6):P1009, POS155.

Pooneh Akhavan (Mount Sinai Hospital, University of Toronto, Toronto); Vivian Bykerk (Mount Sinai Hospital, Toronto); Juan Xiong (The Rebecca MacDonald Center for Arthritis and Autoimmunity, Toronto); Carter Thorne (Southlake Regional Health Care, The Arthritis Program, Newmarket); Janet Pope (University of Western Ontario, London); Gilles Boire (Université de Sherbrooke, Sherbrooke); Carol Hitchon (University of Manitoba, Winnipeg); Edward Keystone (University of Toronto, Toronto); all CATCH investigators (U of T, Toronto).
Discrepancy Between Patient and Physician Global Assessments Over Time in Early Rheumatoid Arthritis.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario.
J Rheumatol 40(6):P1010, POS156.

Susan Bartlett (McGill University, Montreal); Clifton Bingham (John Hopkins University, Baltimore); Juan Xiong (The Rebecca MacDonald Center for Arthritis and Autoimmunity, Toronto); Ernest Choy (King's College Hospital, London); Gilles Boire (Université de Sherbrooke, Sherbrooke); Carol Hitchon (University of Manitoba, Winnipeg); Janet Pope (University of Western Ontario, London); Carter Thorne (Southlake Regional Health Care, The Arthritis Program, Newmarket); Diane Tin (Southlake Regional Health Centre, Newmarket); Boulos Haraoui (University of Montreal, Montreal); Edward Keystone (University of Toronto, Toronto); Vivian Bykerk (Mount Sinai Hospital, Toronto).
Self Management Strategies of Rheumatoid Arthritis Patients Experiencing a disease Flare.
CRA Annual Scientific Meeting, February 13-16, 2013, Ottawa, Ontario. J Rheumatol 40(6):P1017, POS177.