Pr Ariel Masetto, M.D.
Professeur adjoint
Service de rhumatologie
Département de médecine
Faculté de médecine et des sciences de la santé
Université de Sherbrooke
3001, 12e Avenue Nord
Sherbrooke (Québec)  J1H 5N4

Téléphone : 819 564-5261
Télécopieur : 819 564-5265

Courriel : Ariel.Masetto@USherbrooke.ca

Site Internet
Études médicales et postdoctorales

University of São Paulo, Brazil.

Maîtrise en sciences cliniques
  • En cours
    Faculté de médecine et des sciences de la santé
    Université de Sherbrooke
Thèmes de recherche
  • Sclérodermie
  • Capillaroscopie
Axe de recherche
  • Physiopathologie ostéoarticulaire

Subventions de recherche en cours

Early prediction of patient-related and radiological outcomes in patients with recent-onset inflammatory polyarthritis (EPA) using established and novel independent predictors.

Chercheur principal :  Boire G
Co-chercheurs : Cossette P, Daniel C, de Brum-Fernandes A, Dobkin PL, Urgan L, Ménard HA, Arsenault G, Liang P, Bruns A., Masetto A

Organisme subventionnaire :
IRSC
(2011-03/2016)

Étude de dépistage pour les patients à haut risque de développer une spondylarthropathie, avec psoriasis, uvéite ou colite.

Chercheur principal : Masetto A

Organisme subventionnaire :
Canadian Research and Education (CARE) Arthritis
(2013-....)

L'étude du groupe de recherche canadien sur la sclérodermie - Banque de données et d'échantillons.

Chercheur principal : Masetto A

Organisme subventionnaire :
Hôpital général juif
(2012-....)

Programme de reconnaissance et acheminement rapide des patients avec arthrite. CIORA.

Chercheur principal : Masetto A
Co-chercheurs : St-Onge C et al.

Organisme subventionnaire :
Société canadienne de rhumatologie
(2012-....)

Commandites de recherche en cours

Registre des traitements en rhumatologie (polyarthrite rhumatoïde, spondylite ankylosante, arthrite psoriasique) à travers le Canada.

Chercheur principal : Masetto A

Organisme subventionnaire :
Janssen-Ortho inc.

Étude pharmacoépidémiologique d'observation post commercialisation canadienne sur HUMIRA : Évaluation de l'efficacité dans le traitement de l'arthrite psoriasique.

Chercheur principal : Masetto A

Organisme commanditaire :
AbbVie Corp.

Anti-facteur de nécrose tumorale alpha (anti-TNFa): observation, dans la pratique courante, d'un traitement par CimziaMC chez des patients adultes atteints de PR au Canada. Une étude observationnelle, non interventionnelle multicentrique prospective visant à évaluer l'innocuité et l'efficacité du Certolizuma.

Chercheur principal : Masetto A

Organisme commanditaire :
UCB Canada inc.

Évaluation d'Humira dans des conditions de vie réelles chez des patients canadiens atteints de polyarthrite rhumatoïde.  REACH.

Chercheur principal : Masetto A

Organisme commanditaire :
Laboratoires Abbott ltée

Étude prospective, randomisée, contrôlée avec placebo, en double aveugle, multicentrique, en groupes parallèles évaluant l'efficacité, l'innocuité et la tolérance du macitentan auprès de patients atteints d'ulcères digitaux ischémiques associés à de la sclérose systémique.

Chercheur principal : Masetto A

Organisme commanditaire :
Actelion Pharmaceuticals

Publications d'articles (2009-...)

The 15% rule in scleroderma: the frequency of severe organ complications in systemic sclerosis. A systematic review.
Muangchan C; Canadian Scleroderma Research Group (Masetto A), Baron M, Pope J.
J Rheumatol. 2013 Sep;40(9):1545-56. doi: 10.3899/jrheum.121380. Epub 2013 Jul 15. PMID:23858045

Prevention of rheumatoid arthritis: the very first steps.
Masetto A, Beaulieu MC, Boire G.
J Rheumatol. 2013 Jun;40(6):752-4. doi: 10.3899/jrheum.130326. No abstract available. PMID:23728185

Systemic sclerosis in Canada's North American Native population: assessment of clinical and serological manifestations.
Bacher A, Mittoo S, Hudson M, Tatibouet S; Canadian Scleroderma Research Group, Baron M.
J Rheumatol. 2013 Jul;40(7):1121-6. doi: 10.3899/jrheum.121212. Epub 2013 May 15. PMID: 23678158

Association of gastroesophageal factors and worsening of forced vital capacity in systemic sclerosis.
Zhang XJ, Bonner A, Hudson M; Canadian Scleroderma Research Group (Masetto A), Baron M, Pope J.
J Rheumatol. 2013 Jun;40(6):850-8. doi: 10.3899/jrheum.120705. Epub 2013 Apr 1. PMID:23547215

Low socioeconomic status (measured by education) and outcomes in systemic sclerosis: data from the Canadian Scleroderma Research Group.
Mansour S, Bonner A, Muangchan C, Hudson M, Baron M, Pope JE; Canadian Scleroderma Research Group (Masetto A).
J Rheumatol. 2013 Apr;40(4):447-54. doi: 10.3899/jrheum.120570. Epub 2013 Feb 15. PMID: 23418377

Cross-language measurement equivalence of the Center for Epidemiologic Studies Depression (CES-D) scale in systemic sclerosis: a comparison of Canadian and Dutch patients.
Kwakkenbos L, Arthurs E, van den Hoogen FH, Hudson M, van Lankveld WG, Baron M, van den Ende CH, Thombs BD; Canadian Scleroderma Research Group (Masetto A).
PLoS One. 2013;8(1):e53923. doi: 10.1371/journal.pone.0053923. Epub 2013 Jan 11. PMID: 23326538

High prevalence of occult left heart disease in scleroderma-pulmonary hypertension.
Fox BD, Shimony A, Langleben D, Hirsch A, Rudski L, Schlesinger R, Eisenberg MJ, Joyal D, Hudson M, Boutet K, Serban A, Masetto A, Baron M.
Eur Respir J. 2013 Oct;42(4):1083-91. doi: 10.1183/09031936.00091212. Epub 2012 Dec 20. PMID:23258775

Consensus statements for the use of administrative health data in rheumatic disease research and surveillance.Bernatsky S, Lix L, O'Donnell S, Lacaille D; CANRAD Network (Masetto A).
J Rheumatol. 2013 Jan;40(1):66-73. doi: 10.3899/jrheum.120835. Epub 2012 Nov 1. PMID: 23118109

Longitudinal study of renal function in systemic sclerosis.
Caron M, Hudson M, Baron M, Nessim S, Steele R; Canadian Scleroderma Research Group (Masetto A).J Rheumatol. 2012 Sep;39(9):1829-34. doi: 10.3899/jrheum.111417. Epub 2012 Aug 1. PMID: 22859351

Best practices in scleroderma: an analysis of practice variability in SSc centres within the Canadian Scleroderma Research Group (CSRG).
Harding S, Khimdas S, Bonner A, Baron M, Pope J; Canadian Scleroderma Research Group (Masetto A).Clin Exp Rheumatol. 2012 Mar-Apr;30(2 Suppl 71):S38-43. Epub 2012 May 29. PMID: 22691207 

Association of C-reactive protein with high disease activity in systemic sclerosis: results from the Canadian Scleroderma Research Group.
Muangchan C, Harding S, Khimdas S, Bonner A; Canadian Scleroderma Research group (Masetto A), Baron M, Pope J.
Arthritis Care Res (Hoboken). 2012 Sep;64(9):1405-14. doi: 10.1002/acr.21716. PMID: 22556030

Clinical correlates of CENP-A and CENP-B antibodies in a large cohort of patients with systemic sclerosis.Hudson M, Mahler M, Pope J, You D, Tatibouet S, Steele R, Baron M; Investigators of the Canadian Scleroderma Research Group (Masetto A), Fritzler M.
J Rheumatol. 2012 Apr;39(4):787-94. doi: 10.3899/rheum.111133. PMID: 22467948

Treatment of systemic sclerosis complications: what to use when first-line treatment fails--a consensus of systemic sclerosis experts.
Walker KM, Pope J; participating members of the Scleroderma Clinical Trials Consortium (SCTC); Canadian Scleroderma Research Group (CSRG) (Masetto A). Semin Arthritis Rheum. 2012 Aug;42(1):42-55. doi: 10.1016/j.semarthrit. 2012.01.003. Epub 2012 Mar 29. PMID: 22464314

Clinical significance of antibodies to Ro52/TRIM21 in systemic sclerosis.
Hudson M, Pope J, Mahler M, Tatibouet S, Steele R, Baron M; Canadian Scleroderma Research Group (CSRG) (Masetto A), Fritzler MJ.
Arthritis Res Ther. 2012 Mar 6;14(2):R50. doi: 10.1186/ar3763.PMID: 22394602 

Agreement with guidelines from a large database for management of systemic sclerosis: results from the Canadian Scleroderma Research Group.
Pope J, Harding S, Khimdas S, Bonner A; Canadian Scleroderma Research Group (Masetto A), Baron M.
J Rheumatol. 2012 Mar;39(3):524-31. doi: 10.3899/jrheum.110121. Epub 2012 Jan 15. PMID: 22247347

Clinical decision rule to predict the presence of interstitial lung disease in systemic sclerosis.
Steele R, Hudson M, Lo E, Baron M; Canadian Scleroderma Research Group (Masetto A).
Arthritis Care Res (Hoboken). 2012 Apr;64(4):519-24. doi: 10.1002/acr.21583. PMID: 22213733

Rates and correlates of sexual activity and impairment among women with systemic sclerosis.
Levis B, Hudson M, Knafo R, Baron M, Nielson WR, Hill M, Thombs BD; Canadian Scleroderma Research Group (CSRG) (Masetto A).
Arthritis Care Res (Hoboken). 2012 Mar;64(3):340-50. doi: 10.1002/acr.20696. PMID: 22076868

Measuring pain in systemic sclerosis: comparison of the short-form McGill Pain Questionnaire versus a single-item measure of pain.
El-Baalbaki G, Lober J, Hudson M, Baron M, Thombs BD;Canadian Scleroderma Research Group.
J Rheumatol. 2011 Dec;38(12):2581-7. Epub 2011 Oct 1. PMID: 21965643

Anti-centromere antibodies in a large cohort of systemic sclerosis patients: comparison between immunofluorescence, CENP-A and CENP-B ELISA.
Mahler M, You D, Baron M, Taillefer SS, Hudson M; Canadian Scleroderma Research Group(CSRG), Fritzler MJ.
Clin Chim Acta. 2011 Oct 9;412(21-22):1937-43. Epub 2011 Jul 5. PMID: 21756890

Anti-fibrillarin antibody in African American patients with systemic sclerosis: immunogenetics, clinical features, and survival analysis.
Sharif R, Fritzler MJ, Mayes MD, Gonzalez EB, McNearney TA, Draeger H, Baron M; Canadian Scleroderma Research Group, Furst DE, Khanna DK, del Junco DJ, Molitor JA, Schiopu E, Phillips K, Seibold JR, Silver RM, Simms RW; GENISOS Study Group, Perry M, Rojo C, Charles J, Zhou X, Agarwal SK, Reveille JD, Assassi S, Arnett FC.
J Rheumatol. 2011 Aug;38(8):1622-30. Epub 2011 May 15. PMID: 21572159

Expert agreement on EULAR/EUSTAR recommendations for the management of systemic sclerosis.
Walker KM, Pope J; Scleroderma Clinical Trials Consortium; Canadian Scleroderma Research Group.
J Rheumatol. 2011 Jul;38(7):1326-8. Epub 2011 Apr 1. PMID: 21459952

Modeling smoking in systemic sclerosis: a comparison of different statistical approaches.
Hudson M, Lo E, Baron M, Steele R; Canadian Scleroderma Research Group.
Arthritis Care Res (Hoboken). 2011 Apr;63(4):570-8. doi: 10.1002/acr.20416. PMID: 21452268

Observational data to study medication outcomes in systemic sclerosis.
Hudson M, Baron M; Canadian Scleroderma Research Group (CSRG), Steele R.
J Rheumatol. 2011 Mar;38(3):575-7. No abstract available. PMID: 21362793

Reliability of widefield capillary microscopy to measure nailfold capillary density in systemic sclerosis.
Hudson M, Masetto A, Steele R, Arthurs E, Baron M; Canadian Scleroderma Research Group.
Clin Exp Rheumatol. 2010 Sep-Oct;28(5 Suppl 62):S36-41. Epub 2010 Nov 3. PMID: 21050543

Association of pruritus with quality of life and disability in systemic sclerosis.
El-Baalbaki G, Razykov I, Hudson M, Bassel M, Baron M, Thombs BD; Canadian Scleroderma Research Group.
Arthritis Care Res (Hoboken). 2010 Oct;62(10):1489-95. PMID: 20506531

The association between disease activity and duration in systemic sclerosis.
Walker JG, Steele RJ, Schnitzer M, Taillefer S, Baron M; Canadian Scleroderma Research Group, Hudson M.
J Rheumatol. 2010 Nov;37(11):2299-306. Epub 2010 Sep 1. PMID: 20810506

Discordance between patient and physician assessments of disease severity in systemic sclerosis.
Hudson M, Impens A, Baron M, Seibold JR, Thombs BD, Walker JG; Canadian Scleroderma Research Group, Steele R.
J Rheumatol. 2010 Nov;37(11):2307-12. Epub 2010 Sep 15. PMID: 20843907

Systemic sclerosis: establishing diagnostic criteria.
Hudson M, Fritzler MJ, Baron M; Canadian Scleroderma Research Group (CSRG).
Medicine (Baltimore). 2010 May;89(3):159-65.  PMID: 20453602

Comparison of the PHQ-9 and CES-D depression scales in systemic sclerosis: internal consistency reliability, convergent validity and clinical correlates.
Milette K, Hudson M, Baron M, Thombs BD; Canadian Scleroderma Research Group.
Rheumatology (Oxford). 2010 Apr;49(4):789-96. Epub 2010 Jan 25. PMID: 20100794

Is serum albumin a marker of malnutrition in chronic disease? The scleroderma paradigm.
Baron M, Hudson M, Steele R; Canadian Scleroderma Research Group (CSRG).
J Am Coll Nutr. 2010 Apr;29(2):144-51. PMID: 20679150

Prevalence, severity, and clinical correlates of pain in patients with systemic sclerosis.
Schieir O, Thombs BD, Hudson M, Boivin JF, Steele R, Bernatsky S, Hanley J, Baron M; Canadian Scleroderma Research Group.
Arthritis Care Res (Hoboken). 2010 Mar;62(3):409-17. PMID: 20391488

The minimally important difference in clinical practice for patient-centered outcomes including health assessment questionnaire, fatigue, pain, sleep, global visual analog scale, and SF-36 in scleroderma.
Sekhon S, Pope J; Canadian Scleroderma Research Group, Baron M.
J Rheumatol. 2010 Mar;37(3):591-8. Epub 2010 Jan 15. PMID: 20080913

Prevalence and clinical correlates of pruritus in patients with systemic sclerosis.
Razykov I, Thombs BD, Hudson M, Bassel M, Baron M; Canadian Scleroderma Research Group.
Arthritis Rheum. 2009 Dec 15;61(12):1765-70.PMID: 19950328

Malnutrition is common in systemic sclerosis: results from the canadian scleroderma research group database.
Baron M, Hudson M, Steele R; Canadian Scleroderma Research Group.
J Rheumatol. 2009 Dec;36(12):2737-43. Epub 2009 Oct 15. PMID: 19833750

Work disability in systemic sclerosis.
Hudson M, Steele R, Lu Y, Thombs BD; Canadian Scleroderma Research Group, Baron M.
J Rheumatol. 2009 Nov;36(11):2481-6. Epub 2009 Oct 1. PMID: 19797513

Health-related quality of life in systemic sclerosis: a systematic review.
Hudson M, Thombs BD, Steele R, Panopalis P, Newton E, Baron M; Canadian Scleroderma Research Group.
Arthritis Rheum. 2009 Aug 15;61(8):1112-20. Review. PMID: 19644906

Validity of self-reported comorbidities in systemic sclerosis.
Hudson M, Sharma A, Bernstein J; CANADIAN SCLERODERMA RESEARCH GROUP, Baron M.
J Rheumatol. 2009 Jul;36(7):1477-80. Epub 2009 Jun 1. PMID: 19487272

Clinical correlates of self-reported physical health status in systemic sclerosis.
Hudson M, Steele R, Lu Y, Thombs BD, Panopalis P, Baron M; Canadian Scleroderma Research Group.
J Rheumatol. 2009 Jun;36(6):1226-9. Epub 2009 May 15.PMID: 19447939 [PubMed - indexed for MEDLINE]Related articles

Quality of life in patients with systemic sclerosis compared to the general population and patients with other chronic conditions.
Hudson M, Thombs BD, Steele R, Panopalis P, Newton E, Baron M; Canadian Scleroderma Research Group.
J Rheumatol. 2009 Apr;36(4):768-72. Epub 2009 Feb 17.PMID: 19228662

Reports of abnormal cervical cancer screening tests in systemic sclerosis.
Bernatsky S, Hudson M, Pope J, Markland J, Robinson D, Jones N, Docherty P, Abu-Hakima M, Leclerc S, Dunne J, Smith CD, Sutton E, Khalidi N, Mathieu JP, Masetto A, Ligier S, Kaminska E, Baron M; Canadian Scleroderma Research Group.
Rheumatology (Oxford). 2009 Feb;48(2):149-51. Epub 2008 Dec 15. PMID: 19074957