Pr Paul Farand, M.D.
Directeur du Service de cardiologie
Professeur adjoint

Membre de l'axe de recherche et du thème porteur "Diabète, obésité et complications cardiovasculaires" du CRC-Étienne LeBel du CHUS et de la Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke.
Service de cardiologie
Département de médecine
Faculté de médecine et des sciences de la santé
Université de Sherbrooke
3001, 12e Avenue Nord
Sherbrooke (Québec) J1H 5N4

Téléphone : 819 821-8000 poste 74326
Télécopieur : 819 820-6897

Courriel : Paul.Farand@USherbrooke.ca
Études médicales et postdoctorales
  • M.D., Université de Sherbrooke, 2000.
  • Médecine interne, Université de Sherbrooke, 2003.
  • Cardiologie, Université de Sherbrooke, 2006.
M. Sc.

Pharmacologie, Université de Sherbrooke, 2004.

Thèmes de recherche
  • Évaluation de l'utilisation sécuritaire des médications cardiovasculaires, généralement par le biais d'études rétrospectives.
  • Évaluation de l'impact de la structure de la dispensation des soins sur la qualité des soins.
  • Développement et évaluation de nouvelles techniques d'imageries diagnostiques cardiovasculaires ou bien de nouvelles applications des techniques existantes.
Axe et thème porteur de recherche

Diabète, obésité et complications cardiovasculaires.

Subventions de recherche en cours

IMAGE HF 1A 1B ET 1C. Étude multicentrique

  • Chercheur principal (institutionnel) :  Farand P
  • Organisme subventionnaire

    • IRSC/CIHR
    • (2013-....)

Supervision d'étudiants — 5 dernières années

(2e, 3e cycles et stagiaires postdoctoraux)
Dussault, Charles

Programme : Sciences cliniques

Diplôme : M. Sc. / en cours (début en 2012)

Titre de la recherche : Évaluation de l'impact sur la capacité fonctionnelle du traitement de l'hypothyroïdie subclinique en insuffisance cardiaque systolique.

Bourse : S/O

Directeur : Nguyen M.

Co-directeur : Farand P., St-Cyr-Tribble D.

Belly-Côté, Émilie

Programme : Sciences cliniques

Diplôme : M. Sc. / en cours

Titre de la recherche : Étude ROSE : Récupération objective de la fonction systolique évaluée par échographie.

Bourse : S/O

Directeur : Farand P.

Co-directeur : Nguyen M., Dussault C.

Publications d'articles (2010-....)

Impact of hemodialysis on the level of high-sensitivity cardiac troponins T in patients with end-stage renal disease.
Levi M, Bonenfant F, Brouwers FM, Farand P, Corbin F, Nguyen M.
Minerva Cardioangiol. 2014 Nov 12. [Epub ahead of print].  PMID: 25389561

Mitral valve blood cyst detected by multimodality imaging.
Bonenfant F, Essadiqi B, Gahide G, Jeanmart H, Farand P.
Can J Cardiol. 2014 Sep;30(9):1109.e5-6. doi: 10.1016/j.cjca.2014.04.019. Epub 2014 Apr 25. No abstract available. PMID: 25151291

Beta-blockers are associated with increased risk of first cardiovascular events in non-diabetic hypertensive elderly patients.
Brouwers FM, Courteau J, Cohen AA, Farand P, Cloutier L, Asghari S, Vanasse A.
Pharmacoepidemiol Drug Saf. 2014 Nov;23(11):1139-46. doi: 10.1002/pds.3675. Epub 2014 Jul 5.  PMID: 25045055

Effect of age and sex on echocardiographic left ventricular diastolic function parameters in patients with preserved ejection fraction and normal valvular function.
Carvalho JC, Farand P, Do HD, Brochu MC, Bonenfant F, Lepage S.
Cardiol J. 2013;20(5):513-8. doi: 10.5603/CJ.2013.0137. PMID: 24469875

Streptococcus anginosus pyogenic liver abscess following a screening colonoscopy.
Bonenfant F, Rousseau E, Farand P.
Can J Infect Dis Med Microbiol. 2013 Summer;24(2):e45-6. PMID: 24421818

Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B).
Paterson I, Wells GA, Ezekowitz JA, White JA, Friedrich MG, Mielniczuk LM, O'Meara E, Chow B, DeKemp RA, Klein R, Dennie C, Dick A, Coyle D, Dwivedi G, Rajda M, Wright GA, Laine M, Hanninen H, Larose E, Connelly KA, Leong-Poi H, Howarth AG, Davies RA, Duchesne L, Yla-Herttuala S, Saraste A, Farand P, Garrard L, Tardif JC, Arnold M, Knuuti J, Beanlands R, Chan KL.
Trials. 2013 Oct 12;14:332. doi: 10.1186/1745-6215-14-332. PMID: 24119686

Pilot study: can older inactive adults learn how to reach the required intensity of physical activity guideline?
Bouchard DR, Langlois MF, Boisvert-Vigneault K, Farand P, Paulin M, Baillargeon JP.
Clin Interv Aging. 2013;8:501-8. doi: 10.2147/CIA.S42224. Epub 2013 Apr 30. PMID: 23662053

Can we still learn from single center experience after PARTNER?
Daneault B, Fulop TZ, Farand P.World J Cardiol. 2013 Mar 26;5(3):15-7. doi: 10.4330/wjc.v5.i3.15. PMID: 23539487 

Impact of methicillin resistant Staphylococcus aureus contact isolation units on medical care.
Masse V, Valiquette L, Boukhoudmi S, Bonenfant F, Talab Y, Carvalho JC, Alarie I, Carrier N, Farand P.
PLoS One. 2013;8(2):e57057. doi: 10.1371/journal.pone.0057057. Epub 2013 Feb 25. PMID: 23451144

Delayed efficient anticoagulation with heparin in patients with a weight of 110 kg and more treated for acute coronary syndrome.
Joncas SX, Poirier P, Ardilouze JL, Carrier N, Fayad T, Farand P.
Obesity (Silver Spring). 2013 Sep;21(9):1753-8. doi: 10.1002/oby.20029. Epub 2013 Apr 9. PMID: 23404940

Drug utilization reviews: a systematic approach to quality improvement centered on the patient.
Farand P, Cossette B.
MSA 2012. 1(4):1-6.

Role of imaging in penetrating and blunt traumatic injury to the heart.
Co SJ, Yong-Hing CJ, Galea-Soler S, Ruzsics B, Schoepf UJ, Ajlan A, Farand P, Nicolaou S.
Radiographics. 2011 Jul-Aug;31(4):E101-15. Erratum in: Radiographics. 2011 Sep-Oct;31(5):1496. Aljan, Amr [corrected to Ajlan, Amr]. PMID: 21768229

Biorhythm theory does not predict admission for acute myocardial infarction.
Joncas SX, Carrier N, Nguyen M, Farand P.
J Altern Complement Med. 2011 Feb;17(2):143-6. Epub 2011 Feb 7.
PMID: 21299417

Acute and recurring pericarditis: More colchicine, less corticosteroids.
Farand P, Bonenfant F, Belley-Côté EP, Tzouannis N.
World J Cardiol. 2010 Dec 26;2(12):403-7. PMID: 21191540

Evaluation of bleeding risk in patients exposed to therapeutic unfractionated or low-molecular-weight heparin: a cohort study in the context of a quality improvement initiative.
Cossette B, Pelletier ME, Carrier N, Turgeon M, Leclair C, Charron P, Echenberg D, Fayad T, Farand P.
Ann Pharmacother. 2010 Jun;44(6):994-1002. Epub 2010 May 4. PMID: 20442353

Traitement des péricardites aiguës et récidivantes : Davantage de place pour la colchicine, moins pour les corticostéroïdes.
Farand P, Belley-Côté EP
Actualité médicale, Med Actuel 14 juillet 2010.

Résumés

Dault Roxanne, Vanasse Alain, Farand Paul, LeTemplier Geneviève, Blais Lucie, Perrault Sylvie, Beauchesne Marie-France.  Patterns of use of anticoagulants for the venous thromboembolism at the CHUS. (Poster facilitated session at Canadian Society of Hospital Pharmacists (CSHP) Professional Practice Conference (PPC), Toronto 2014)

TZ Fulop, É Noiseux, B Daneault, P Farand. Value of stress echocardiography for further evaluation of equivocal treadmill test at high workload (over 11 METS) (Highlighted Poster at the Canadian Cardiovascular Congress, 2013).

M Theriault, M De la paz ricapito, F Paredes, P Diez Martinez, P Farand, G Gahide. Systematic comparison of CT scan and retrograde venography for depicting the cardiac venous system prior to Cardiac Resynchronisation Therapy. (Poster presentation at 2013 RSNA Chicago).

France Varin, Julie Leblond, Nathalie Marcotte, Céline Dupont, Marie-Claude Michel, Élaine Pelletier, Martin Turgeon, Louise Deschênes, Paul Farand, Daniel Froment, Pierre Gaudreault, Raghu Rajan. Utilisation d’abréviations et de symboles dans les ordonnances dans les centres hospitaliers universitaires du Québec : Analyse descriptive. (Poster presentation at Regroupement québécois de recherche sur l'usage des medicaments 2013).

Frederieke M. Brouwers, Alan A. Cohen, Josiane Courteau, Paul Farand, Lyne Cloutier, Shabnam Asghari, Alain Vanasse. Comparative efficacy of blood pressure lowering in primary prevention for elderly patients.  International Society for Pharmacoeconomics and Outcomes Research (ISPOR) 4th Latin America Conference, September 2013 at Buenos Aires, Argentina. (Poster abstract).

Céline Dupont, Julie Leblond, Nathalie Marcotte, Marie-Claude Michel, Élaine Pelletier, Martin Turgeon, France Varin, Louise Deschênes, Paul Farand, Daniel Froment, Pierre Gaudreault, Raghu Rajan. Utilisation d’abréviations et de symboles dans les ordonnances dans les centres hospitaliers universitaires du Québec analyse descriptive. (Poster abstract APES 2013).

Frederieke M. Brouwers, Josiane Courteau, Alan A. Cohen, Paul Farand, Lyne Cloutier, Shabnam Asghari, Alain Vanasse. Beta-blockers are associated with less effective primary prevention among non-diabetic elderly hypertensive patients: A series of population-based nested case-control studies. (Poster abstract, April 2013, London).

Sébastien Xavier Joncas, Sylvie Bourque, Christina St-Onge, Paul Farand. Suivi des qualités docimologiques des questions répétées lors des évaluations intrafacultaires (Poster abstract at 6e Forum international francophone de pédagogie des sciences de la santé - FIFPSS, 2013).http://www.pedagogie-medicale.org/

Danny Bélanger, Caroline Lacroix, François Belzile, Paul Farand, Michel Nguyen, Gérald Gahide. Imaging Findings on MR Scan in Acute Myocarditis. (Abstract at RSNA Scientific Assembly and Annual Meeting, November 2012. Chicago).

Julie Leblond, Nathalie Marcotte,Céline Dupont,Marie-Claude Michel, Élaine Pelletier, Martin Turgeon, Franc Varin, Louise Deschênes, Paul Farand, Daniel Froment, Pierre Gaudreault, Raghu Rajan. Descriptive analysis of the opioid orders in the university teaching hospitals of Quebec - phase III – 2011(Poster abstract the Canadian Agency for Drugs and Technologies in Health Symposium, St-John 2013).

Joncas Sebastien Xavier, Ayala-Paredes Felix, Carrier Nathalie, Farand Paul. Real life survival of implantable cardioverter defibrillator (ICD) recipient for primary prevention of sudden cardiac death in heart failure. (Poster abstract at the Canadian Cardiovascular Congress, 2012).

Julie Leblond, Nathalie Marcotte,Céline Dupont,Marie-Claude Michel, Élaine Pelletier, Martin Turgeon, Franc Varin, Louise Deschênes, Paul Farand, Daniel Froment, Pierre Gaudreault, Raghu Rajan. Description des ordonnaces de narcotiques dans les CHU du Québec, Phase III. (Poster abstract APES 2012).

M. Ricapito; S. Rivera; M. Badra Verdú; J F. Roux; P. Farand; F. Ayala Paredes; G. Gahide. Accuracy of multislice cardiac tomography to depict cardiac venous anatomy before cardiac resynchronization therapy. Poster presentation. Annual Meeting of the Spanish Society of Cardiology 2012. Sevilla. http://www.congresosec.org/web/recursos/pdf/SEC2012_Final.pdf

Frédéric D’Aragon Émilie Belley Cote, Serge Lepage, Btissama Essadiqi, Marianne Coutu, Stephane Coutu, Paul Farand. Hemodynamic Parameter Variations in Relation to Different Levels of Positive End-Expiratory Pressure in a Post-Operative Context. Poster abstract at Canadian Anesthesiologists’ Society. Quebec 2012.

C. Dussault, R. Harvey, P. Farand, M. Paulin, M-E Pelletier, M. Nguyen Routine angiographic follow-up after left main coronary artery percutaneous  coronary intervention: Results of the Sherbrooke Registry. Poster abstract at Annual Cardiovascular Conference. Lake Louise 2012.

Belley-Côté, EP, D’Aragon, F, Tzouannis, N, Paulin, M, Lepage, S, Coutu, S, Essadiqi, B, Coutu, M, Farand, P. Hemodynamic parameter variations in relation to different levels of positive end-expiratory pressure in a post-operative context. Oral abstract at Annual Cardiovascular Conference. Lake Louise 2012. (First prize for oral presentation).

C. Lacroix, D. Bélanger, P. Farand, F. Belzile, G. Gahide  MR imaging in hypertrophic cardiomyopathy. Educational Exhibit ECR Vienna, Austria 2012.

C. Lacroix, D. Bélanger, P. Martin, P. Farand, F. Belzile, G. Gahide MR imaging in suspected acute myocarditis. Educational Exhibit ECR Vienna, Austria 2012.

Mikael Mongeon, Danny Bélanger, Paul Farand, Andrew J Benko, Michel Nguyen, Gerald Gahide. Imaging findings of Endocarditis on Multidetector CT scan. (Abstract at RSNA 2011, 97th Scientific Assembly and Annual Meeting, November 2011. Chicago).

Luc Cormier, Michel Nguyen, Paul Farand. Taux de mortalité après une intervention coronarienne percutanée. (Poster at XIII Congrès francophone de Cardiologie Interventionnelle Paris, France, Octobre 2011).

MC Michel, C Dupont, L Deschenes, E Pelletier, M Turgeon, F Varin, P Farand, D Froment, P Gaudreault, R Rajan, L Bergeron. Descriptive analysis and utilization review of meropenem in five university teaching hospitals. (Poster abstract at ICAAC 2011 Interscience Conference on Antimicrobial Agents & Chemotherapy Medical Conference, Oncology Medical Congress, USA, Chicago.)

M. Berthelot-richer, F. Ayala-Paredes, P. Farand, S. Lepage, B. Essadiqi, J. Roux, M. Badra Verdu, N. Carrier, T. Fayad. Outcome of primary prevention ICD patients based on late recovery of left ventricular ejection fraction. (Oral abstract presented at the Canadian Cardiovascular Congress, 2011)

F. Bonenfant, B. Cossette, V. Nault, M. Turgeon, M. Paulin, D. Echenberg, P. Charron, M. Lépine, T. Fayad,P. Farand. Risk of supratherapeutic aPTT in the absence of an initial unfractionated heparin bolus (Poster abstract at the Canadian Cardiovascular Congress, 2011).

JONCAS, S., POIRIER, P., CARRIER, N., FAYAD, N., FARAND, P.  Delayed anticoagulation with a weight-adjusted heparin nomogram in very obese patients: a retrospective study. Poster abstract at Annual Cardiovascular Conference. Lake Louise 2011. (First prize for poster presentation).

Cormier, L., Jean, J., Lepage, S., Ayala-Paredes, F., Roux, J.-F., Do, D.H., Carrier, N., Diab, H., Farand, P. Mitral-Doppler Measurements are Weakly Correlated with the Risk of New-Onset Atrial Fibrillation in Patients with Cryptogenic Stroke. Poster presentation (accepted): International Stroke Conference 2011 (AHA). Los Angeles Feb 2011.

F Bonenfant, DH Do, S Lepage, B Essadiqi, M Brochu, P Farand.  Rapid learning curve with good clinical results of a new exercise echocardiography program. Poster presentation at 8e concours annuel d'affiches scientifiques de la Société des sciences vasculaires du Québec (SSVQ) 2009. http://www.ssvq.org

Pelletier, M.E., Cossette, B., Harvey, R., Nguyen, M., Bérubé, S., Gervais A., Dalery, K., Farand, P. High risk of bleeding among patients with acute coronary syndrome who receive heparin and who are already treated with warfarin. Poster presentation at 8e concours annuel d'affiches scientifiques de la Société des sciences vasculaires du Québec (SSVQ) 2009. http://www.ssvq.org

DH Do, EP Belley-Côté, AC Carpentier, S Lepage, M Nguyen, P Farand.  Glycemic response after maximal exercise stress test in not an alternative way to screen glucose intolerance and diabetes mellitus. Can J Cardiol. 2010 oct 2010 suppl (poster abstract presented at the Canadian Cardiovascular Congress, 2010).

F Bonenfant, DH Do, S Lepage, B Essadiqi, M Brochu, P Farand. Rapid learning curve with good clinical results of a new exercise echocardiography program. Can J Cardiol. 2010 oct 2010 suppl (poster abstract presented at the Canadian Cardiovascular Congress, 2010).

M Bachand, M Houle, C St-Pierre, P Farand. Outcome of patients subjected to mild therapeutic hypothermia after successful resuscitation from cardiac arrest. Can J Cardiol. 2010 oct 2010 suppl (poster abstract presented at the Canadian Cardiovascular Congress, 2010).

Mampuya, W., Broochu, M.C., Do, D.H., Essadiqi, B., Farand, P., Lepage, S. A large retrospective study of aortic stenosis progression. Can J Cardiol. 2010 oct 2010 suppl (poster abstract presented at the Canadian Cardiovascular Congress, 2010).

Belley-Côté, E.P., Tzouannis, N., Coutu, M., Dalery, K., Lepage, S., Farand, P. A retrospective study of embolic outcomes following bioprosthetic valve replacement surgery in the early postoperative period of patients not receiving routine postoperative anticoagulation after discharge. Can J Cardiol. 2010 oct 2010 suppl (Oral abstract presented at the Canadian Cardiovascular Congress, 2010).

Mampuya, W., Brochu, M.C., Coutu, M., Do, D.H., Essadiqi, B., Farand, P., Normandin, D., Greentree, D., Lepage, S. Preliminary observations on tricuspid vave annuloplasty evaluation with stress echocardiography. Can J Cardiol. 2010 oct 2010 suppl (Oral abstract presented at the Canadian Cardiovascular Congress, 2010).

Fulöp T.Z., Lepage, S., Farand, P. Chez les patients candidats à une intervention, une chirurgie précoce est associée à une amélioration de la survie des patients avec sténose aortique et dysfonction systolique sévères. Oral presentation presented at the annual congress, Club de recherche clinique du Québec 2010.

Mampuya, W., Do, H., Farand, P., Brochu, M.-C., Essadiqi, B., Lepage, S. A large retrospective cohort study of aortic stenosis Progression. Oral presentation: SA Heart Association Congress 2010. Sun City South Africa August 2010.

Joncas, S., Poirier, P., Carrier, N., Fayad, N., Farand, P.  Delayed anticoagulation with a weight-adjusted heparin nomogram in very obese patients: a retrospective studyPoster session: Nutrition, Physical Activity and Metabolism Scientific Sessions 2010 (AHA) San Francisco March 2010

Carvalho, J.-C., Do, D.H., Farand, P., Brochu, M.-C., Lepage, S.  Effect of age and sex on echocardiographic left ventricular diastolic function parameters. Poster session. EUROEcho 2009. Madrid (Spain), December 2009.  

Carvalho, J.-C., Farand, P., Do, D.H., Brochu, M.-C., Peage, S.  Left ventricular concentric remodeling is not associated with increased mortality and worse cardiovascular outcomes in patients with otherwise normal cardiac systolic and valvular function. Poster session. EUROEcho 2009. Madrid (Spain), December 2009.  

Nosair, M., Farand, P., The Negative Predictive Value of Exercise Treadmill Testing at One Year. Poster presentation at 8e concours annuel d'affiches scientifiques de la Société des sciences vasculaires du Québec (SSVQ) 2009. http://www.ssvq.org

Nosair, M., Farand, P. The negative predictive value of exercise treadmill testing at one year. Can J Cardiol. 2009 oct 2009 suppl. (oral abstract presented at the Canadian Cardiovascular Congress, 2009).

Carvalho, J.-C., Do, D.H., Farand, P., Brochu, M-C. Lepage S.  Effect of age and sex on echocardiographic left ventricular diastolic function parameters in patients with normal systolic function. Can J Cardiol. 2009 oct 2009 suppl (oral abstract presented at the Canadian Cardiovascular Congress, 2009).

Berthelot-Richer, M., Carrier, N., Farand, P. Effect of age on reference intervals for pulmonary artery systolic pressure among echocardiographically normal older subjects. Can J Cardiol. 2009 oct 2009 suppl (oral abstract presented at the Canadian Cardiovascular Congress, 2009).

Plante, G.E., Gingras, M., Farand, P., Letellier, M. Endothélium/interstitium/organes cibles en physiopathologie. Oral abstract at 51e réunion annuelle du Club de recherche clinique du Québec (CRCQ) september 2009.
http://crcq.crc.chus.qc.ca/media/document/CRCQ_Programme_51e_reunion_annuelle.pdf

Gingras, M., Farand, P., Safar M.E., Plante G.E. Réflexions sur une image séculaire de l'Adventice. Oral abstract at 51e réunion annuelle du Club de recherche clinique du Québec (CRCQ) september 2009. http://crcq.crc.chus.qc.ca/media/document/CRCQ_Programme_51e_reunion_annuelle.pdf

Pelletier, M.E., Cossette B., Carrier N., Turgeon M., Leclair C., Charron P., Echenberg D., Nguyen M., Farand P. Bleeding with heparin : A retrospective study in the context of quality of care improvement. Can J Cardiol. 2008 oct 24 suppl SE (oral abstract presented at the Canadian Cardiovascular Congress, 2008).

St-Phard W., Farand P., Scazzuso F., Ayala-Paredes F.Prevalence of a new electrocardiography marker of sudden death in a syncope population. Can J Cardiol. 2008 oct 24 suppl SE (oral abstract presented at the Canadian Cardiovascular Congress, 2008).

Plante, G.E., Farand, P. Atherogenesis : A luminal and/or adventitial endothelium aortic dysfunction. Atherosclerosis Supplements, Volume 9, Issue 1, May 2008, Page 230 (oral abstract presented at the 77th Congress of the European Atherosclerosis Society, 2008, Istanbul, Turkey).

Plante, G.E., Farand, P., Struijker-Boudier, H.A., Safar, M.E. Essential hypertension is initiated in renal microcirculation, followed by increased conduit artery stiffness to eventuate in resistance vessels. Journal of Vascular Research, 2008 45 (S1) page 84 (oral abstract presented at the 9th International Symposium on Resistance Arteries, Hamilton Island, Australia 2008. www.ISRA08.unsw.edu.au).