Exemples de travail

Quelques exemples d’histologie de tissus en coloration H&E et de colorations de routine.

Visualisation et évaluation de constituants cellulaires spécifiques à l’aide d’anticorps par les techniques d’immunofluorescence et d’immunohistochimie.

Visualisation ultrastructurale de constituants cellulaires.

Publications associées

  1. Roy SAB, Langlois MJ, Carrier JC, Boudreau F, Rivard N and Perreault N. 2012. Dual regulatory role for Pten in specification of intestinal endocrine cell subtypes. World J of Gastro 18(14): 1579-­‐1589.
  2. Maloum F, Allaire JM, Gagné-­‐Sansfaçon J, Roy E, Belleville K, Sarret P, Morisset J, Carrier JC, Mishina Y, Kaestner KH and Perreault N. 2011. Epithelial Bmp signaling is required for proper specification of epithelial cell lineages and gastric endocrine cells. Am J Physiol 300(6): G1065-­‐79.
  3. Allaire J, Darsigny M, Marcoux SS, Roy SAB, Schmouth JF, Umans L, Zwijsen A, Boudreau F and Perreault N. 2011. Loss of Smad5 leads to disassembly of the apical junctional complex and increasing susceptibility to experimental colitis. Am J Physiol 300 (4):G586-­‐97.
  4. Lussier CR, Brial F, Roy SAB, Langlois MJ, Verdu EF, Rivard N, Perreault N and Boudreau F. 2010. Loss of Hepatocyte-­‐Nuclear-­‐Factor-­‐1α Impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiation. PloS One 24 (8):12 378.
  5. Benoit YD, Paré F, Francoeur C, Jean D, Tremblay E, Boudreau F, Escaffit E and Beaulieu JF. 2010. Cooperation between HNF-­‐1alpha, Cdx2, and GATA-­‐4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line. Am J Physiol 298 (4):G504-­‐17.
  6. Lussier CR, Babeu JP, Auclair BA, Perreault N and Boudreau F. 2008. Hepatocyte nuclear factor-­‐4 alpha (HNF-­‐4α) promotes differentiation of intestinal epithelial cells in co-­‐culture system. Am J Physiol 294(2):G418-­‐28.
  7. Auclair BA, Benoit YD, Rivard N, Mishina Y and Perreault N. 2007. Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage. Gastroenterology 133: 887-­‐896.
  8. Boudreau F, Lussier CR, Mongrain S, Darsigny M, Drouin JL, Doyon G, Ran Suh E, Beaulieu JF, Rivard N and Perreault N. 2007. Loss of cathepsin L activity promotes claudin-­‐1 overexpression and intestinal neoplasia. FASEB J 21(14): 3853-­‐65.
  9. Groulx JF, Gagné D, Benoit YD, Martel D, Basora N, Beaulieu JF. 2011. Collagen VI is a basement membrane component that regulates epithelial cell-­‐fibronectin interactions. Matrix Biol. 30(3):195-­‐206.