Marcel Bastin, Ph.D.

Professeur associé

Postes académiques

1978-1981  Professeur adjoint, Département de microbiologie

1981-1986  Professeur agrégé, Département de microbiologie

1986-2014  Professeur titulaire

1992-2004  Professeur titulaire et directeur, Département de biochimie et directeur du programme de baccalauréat en biochimie

Publications

Université de Liège

1. Gaspar, Th. et M. Bastin, Bull. Soc. Roy. Sc. Liège, 11-12 (1963) 830-835.

 2. Bastin, M. Bull. Soc. Roy. Sc. Liège, 5-6 (1964) 349-353.

 3. Bastin, M. Bull. Soc. Roy. Sc. Liège, 9-10 (1964) 588-605.

 4. Bastin, M. Bull. Soc. Roy. Sc. Liège, 11 (1964) 678-683.

5. Gaspar, Th., M. Bastin and C. Leyh, Bull. Soc. Roy. Sc. Liège, 12 (1964) 844-852.

 6. Gaspar, Th., M. Bastin et C. Leyh, Bull. Acad. roy. Belgique, 98 (1964) 799-815.

 7. Gaspar, Th., C. Leyh et M. Bastin, Bull. Soc. roy. Bot. Belgique, 98 (1964) 23-34.

 8. Schumaker, R. and M. Bastin, Bull. Soc. Roy. Sc. Liège, 1-2 (1965) 42-48.

 9. Gaspar, Th., P-E., Pilet et M. Bastin, Physiol. Vég. 2 (3) (1965) 221-231.

10. Bastin, M, Th. Gaspar et C. Leyh, C.R. Acad. Sc. Paris, 260 (1965) 4050-4052.

11. Leyh, C. et M. Bastin, C.R. Acad. Sc. Paris, 262 (1966) 2593-2596.

12. Bastin, M. Planta, 71 (1966) 189-194.

13. Ruwet, M. Bull. Soc. Roy. Sc. Liège, 1-2 (1966) 142-149.

14. Bouillenne, C. Bull. Soc. Roy. Sc. Liège, 1-2 (1966) 150-158.

15. Bastin, M. Photochem. and Photobiol. 5 (1966) 423-429.

16. Bastin, M. Bull. Soc. Roy. Sc. Liège, (1966) 123-140.

17. Bouillenne-Walrand, M., C. Leyh, M. Bastin et Th. Gaspar, Bull. Soc. roy. Bot.   Belgique, 100 (1967) 153-162.

18. Bastin, M. and H. Dijkmans, Zeitz. Pflanzenphysiologie, 58 (1967) 84-85.

19. Ruwet, M. et M. Bastin, Bull. Soc. Roy. Sc. Liège, 3-4 (1967) 166-172.

20. Bastin, M. Planta, 73 (1967) 243-249.

21. Bastin, M. Zeitz. Universität Rostock, 16 (1967) 605-606.

22. Bastin, M. et H. Dijkmans, Bull. Soc. Franç. Physiol. Végét. 13 (1967) 257-263.

23.Bastin, M. In « Transport of Plant Hormones » North-Holland, Amsterdam (1968) 135-155.

Middle East Technical University, Ankara

24. Bastin, M. and A. Akgün., METU Journ. Pure and Applied Sci. 1 (3) (1968) 257-266.

25. Bastin, M., C. Leyh and M. Bouillenne-Walrand. METU Journ. Pure and Applied Sc. 2 (3) (1969) 209-215.

26. Bastin, M. Can. J. Biochem. 46 (1968) 1339-1343.

27. Bastin, M. C.R. Acad. Sc. Paris, 271 (1970) 1284-1287.

28. Bastin, M. and H. Dijkmans, Can. J. Biochem. 48 (1970) 316-321.

29. Bastin, M. and O. Ünlüer, Can. J. Bot. 50 (1972) 727-731.

30. Özer, N. and M. Bastin, Verlag Chemie, Weinheim, 71-82 (1971)

31. Bastin, M. and O. Ünlüer, Planta, 102 (1972) 357-361.

University of Wisconsin, Madison

32. Bastin, M., and P. Kaesberg. A possible replicative form of Brome mosaic virus RNA 4. Virology 72 (1976) 536-539.

33. Bastin, M. and P. Kaesberg. Radioactive labelling of Brome Mosaic Virus. J. Gen. Virol. 26 (1975) 321-325.33.

34. Bastin, M., R. Dasgupta, T.C.Hall, and P. Kaesberg. Similarity in structure and function of the 3’-terminal region of the four Brome mosaic viral RNAs. J. Mol. Biol. 103 (1976) 737-745.

35. Bastin, M., and T.C. Hall. Interaction of elongation factor 1 with aminoacylated Brome mosaic virus and tRNA’s. J. Virol. 20 (1976) 117-122.

Université de Sherbrooke

36. Bastin, M., D. Bourgaux-Ramoisy, and P. Bourgaux. Biological properties of Polyoma DNA fragments cloned in plasmid pBR322. J. gen. Virol. 50 (1980) 179-184.

37. Parent, C., M.E, Blais-Foley, and M. Bastin. Molecular cloning of defective polyoma virus DNA molecules. Arch. Intern. Physiol. Biochim. 88 (1980) B172-B173.

38. Bastin, M. Molecular cloning in plasmid pBR322 giving altered expression of the tetracycline resistant gene. J. Gen. Microb. 123 (1981) 187-191.

39. Gélinas, C., and M. Bastin. Tumorigencity of cloned polyoma DNA in new-born rats. Arch. Intern. Physiol. Biochim. 89 (1981) B57-B58.

40. Gélinas, C., L. Bouchard, and M. Bastin. Tumorigenic activity of cloned polyoma virus DNA in newborn rats. Experientia 37 (1981) 1074-1075.

41. Parent, C., and M. Bastin. Tranformation of rat fibroblasts by cloned defective polyoma DNA. Arch. Intern. Physiol. Biochim. 89 (1981) 225-233.

42. Asselin, C., C. Gélinas and M. Bastin. Role of the three polyoma virus early proteins in tumorigenesis. Mol. Cell. Biol. 3 (8) (1983) 1451-1459.

43. Gélinas, C., S. Masse, and M. Bastin. Mlt mutation in the polyomavirus genome impairing a function of the middle T protein. J. Virol. 51 (1) (1984) 242-246.

44. Asselin, C., C. Gélinas, P.E. Branton, and M. Bastin. Polyoma middle T antigen requires cooperation from another gene to express the malignant phenotype in vivo. Mol. Cell. Biol. 4 (4) (1984) 755-760.

45. Gélinas, C., and M. Bastin. Malignant transformation of rat cells by the polyomavirus middle T gene. Virol. 146 (1985) 233-245.

46. Asselin, C., and M. Bastin. Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts. J. Virol. 56 (3) (1985) 958-968.

47. Bourgaux, P., M. Bastin, D. Bourgaux-Ramoisy, P. Chartrand, D. Gibson, J.P. Thirion et J. Weber. Le genie génétique à la Faculté de médecine de l’Université de Sherbrooke. L’Union médicale du Canada. 115 (1986) 840-842.

48. Bouchard, L., J. Vass-Marengo, and M. Bastin. Expression of the malignant phenotype in rat fibroblasts transfected with the polyomavirus transforming genes. Virol. 155 (1986) 1-12.

49. Asselin, C., J. Vass-Marengo, and M. Bastin. Mutation in the polyomavirus genome that activates the properties of large T associated with neoplastic transformation. J. Virol. 57 (1) (1986) 165-172.

50. Bouchard, L., F. Mathieu, and M. Bastin. High-frequency changes in transcriptional activity in polyomavirus-transformed cell lines. J. Virol. 61 (8) (1987).

51. Roberge, C., and M. Bastin. Site-directed mutagenesis of the polyomavirus genome: replication-defective large T mutants with increased immortalization potential. Virol. 144 (1988) 1469-1475.

52. Gélinas, C., B. Schaffhausen, B. Bockus, A. Ratiarson, and M. Bastin. Mutations in polyomavirus middle T antigen affecting tumorigenesis. Virol. 170 (1989) 193-200.

53. Renzo, A., L. Bouchard, C.J. Mongeau, and M. Bastin. Effect of CpG-rich sequences in transformation and tumorigenesis by polyomavirus. Oncogene 4 (1989) 1469-1475.

54. Larose, A., L. St-Onge, and M. Bastin. Mutations in polyomavirus large T affecting immortalization of primary rat embryo fibroblasts. Virol. 176 (1990) 98-105.

55. St-Onge, L., L. Bouchard, S. Laurent, and M. Bastin. Intrachromosomal recombination mediated by papovavirus large T antigens. J. Virol. 64 (6) (1990) 2958-2966.

56. Larose, A., N. Dyson, M. Sullivan, E. Harlow, and M. Bastin. Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization. J. Virol. 65 (5) (1991) 2308-2313.

57. St-Onge, L., and M. Bastin. Amplification of polyomavirus DNA sequences stably integrated in rat cells. Nucleic acids res. 19 (23) (1991) 6619-6625.

58. Bastin, M. Polyomavirus-mediated transformation: a model of multistep carcinogenesis. Cancer Invest., 10 (1992) 85-92.

59. Bastin, M., St-Onge, L., and Bouchard, L. A mathematical model of homologous recombination in cultured cells. J. Theoretical Biol. 156 (1992) 513-524.

60. St-Onge, L., and Bastin, M. Amplification mediated by polyomavirus large T antigen defective in replication. J. Virol. 67 (1993) 5025-5029.

61. St-Onge, L., Bouchard, L., and Bastin, M. High-frequency recombination mediated by polyomavirus large T antigen defective in replication. J. Virol., 67 (1993) 1788-1795.

62. St-Onge, L., and Bastin, M. Transcription activation mediated by chromosomal inversion in rat cells. Oncogene 9 (1994) 781-789.

63. Laurent, S., and Bastin, M. Elements of the polyomavirus replication origin required for homologous recombination mediated by large T antigen. J. Virol. 69 (1995) 7304-7308.

64. Laurent, S., Francès, V. and Bastin, M. Intrachromosomal recombination mediated by the polyomavirus large T antigen. Virology 206 (1995) 227-233.

65. Francès V., and Bastin, M. Gene targeting in rat embryo fibroblasts promoted by the polyomavirus large T antigen. Nucleic Acids Res. 24 (1996) 1999-2004.

66. Asselin, C., Sullivan, M and Bastin, M. Spliceable vectors encoding the polyomavirus middle and small T antigens. Gene 203 (1997) 175-181.

67. Lemieux, B and Bastin, M. Polyomavirus large T mutants affected in viral DNA replication. Virology 269 (2000) 370-376.

68. Kaymak, B., Reynaud, C. and Bastin, M. (2000). Specific origin-DNA unwinding activity by polyomavirus mutant defective in viral DNA replication.