Peer reviewed published papers

  • Charlotte Gillium, Mihaela Friciu, Nicolas Abatzoglou and Grégoire Leclair. (2018). Stability of Extemporaneously Prepared Acetazolamide Oral Suspension at Two Temperatures. The Journal of Pediatric Pharmacology and Therapeutics. Submitted
  • Emmanuel Vachon Lachance, Nicolas Abatzoglou, Ryan Gosselin, Carl Duchesne and Antoine Cournoyer. (2018). Potassium chloride caking tendency: a parametric study of cake break energy. Advanced Powder Technology. 29: 2140-2152.
  • Sophie Hudon, Pierre-Philippe Lapointe-Garant, Jean-Sébastien Simard, Albert Pichieri, Stephen Hammond, George Sienkiewicz and Nicolas Abatzoglou. (2018). Evaluation of a dry coating technology as a substitute for roller compaction for dry agglomeration applications in the pharmaceutical industry. Journal of Pharmaceutical Innovation. In Press
  • Sophie Hudon, Pierre-Philippe Lapointe-Garant, Jean-Sébastien Simard, Albert Pichieri, Stephen Hammond, George Sienkiewicz, Michel Perrier and Nicolas Abatzoglou. (2018). Evaluation of a dry coating technology as a substitute for roller compaction for dry agglomeration applications in the pharmaceutical industry. Journal of Pharmaceutical Innovation. In Press
  • Pedro Durão, Clémence Fauteux-Lefebvre, Jean-Maxime Guay, Jean-Sébastien Simard, Nicolas Abatzoglou & Ryan Gosselin. (2018). Specificity of process analytical tools in the monitoring of multicomponent pharmaceutical powders. Pharmaceutical Development and Technology DOI: 10.1080/10837450.2018.1492617.
  • Himmat Dalvi, Clémence Fauteux-Lefebvre, Jean-Maxime Guay, Nicolas Abatzoglou and Ryan Gosselin. (2018). Concentration monitoring with near infrared chemical imaging in a tableting press. Journal of Spectral Imaging doi: 10.1255/jsi.2018.a5. 7(a5): 1-18.
  • S. Hudon*, P.-Ph. Lapointe-Garant, J.-S. Simard, A. Pichieri, S. Hammond, G. Sienkiewicz, N. Abatzoglou and M. Perrier. (2017). Evaluation of a dry coating technology as a substitute for roller compaction for dry agglomeration applications in the pharmaceutical industry. Powder Technology. Accepted
  • R. Gosselin, C. Fauteux-Lefebvre*, P. Durão*, J.-M. Guay, J.-S. Simard and N. Abatzoglou. (2017). Specificity of Process Analytical Tools in the monitoring of multicomponent pharmaceutical powders. Journal of Pharmaceutical and Biomedical Analysis. Submitted
  • K. Yekpe*, N. Abatzoglou, B. Bataille, R. Gosselin, T. Sharkawi, J.-S. Simard, A. Cournoyer. (2017). Developing a Quality by Design Approach to Model Tablet Dissolution Testing: an Industrial Case Study. Pharmaceutical Development and Technology dx.doi.org/10.1080/10837450.2017.1392566. Available online
  • P. Durão, C. Fauteux-Lefebvre, J.-M. Guay, J.-S. Simard, N. Abatzoglou, and R. Gosselin*, Using multiple Process Analytical Technology probes to monitor multivitamin blends in a tableting feed frame, TALANTA, Vo. 164, 2017, pp. 7-15.
  • P. Durão, N. Abatzoglou, J.-M. Guay and R. Gosselin*,Monitoring the Concentration of Flowing Pharmaceutical Powders in a Tableting Feed Frame, Pharmaceutical Development & Technology, July 2015. DOI: 10.3109/10837450.2015.1102278.
  • M.-J. Colbert, M. Grandbois and N. Abatzoglou, Identification of inter-particular forces by atomic force microscopy and how they relate to powder rheological properties measured in shearing tests,Powder Technology, Vol. 284, 2015, pp. 396-402.
  • K. Yekpe, N. Abatzoglou, R. Gosselin, B. Bataille, T. Sharkawi, A. Cournoyer, J.-S. Simard, Predicting the dissolution behavior of pharmaceutical tablets with NIR chemical imaging, International Journal of Pharmaceutics. doi: 10.1016/j.ijpharm.2015.03.060. 486(1-2): 242-251
  • J.-M. Guay, P.-Ph. Lapointe-Garant, R. Gosselin, J.-S. Simard and N. Abatzoglou, Development of a multivariate light-induced fluorescence (LIF) PAT tool for in-line quantitative analysis of pharmaceutical granules in a V-blender,Eur. J. of Pharmac. and Biopharmac., Vol. 86, Issue 3, April 2014, pp. 524–531.
  • R. Gosselin, N. Abatzoglou, Ph. Quinn and J. Salvas, Novel methodologies for determining the mineral content of complex multivitamin tablets,European Pharmaceutical Review, Vol. 19, Issue 14, pp. 62-68, 2014.
  • N. Abatzoglou*, E. Castellanos Gil and R. Gosselin, Evaluating the influence of hopper geometry on radial and axial concentration profiles in flowing granular mixtures, Special Edition: Near Infrared Spectroscopy: In-depth focus 2013, European Pharmaceutical Review, February 2013.
  • R. Gosselin*, M.-O. Lacombe and N. Abatzoglou, Determining Bulk Powder Particle Size through Texture Analysis,American Pharmaceutical Review, February 2013.
  • A.-M. Demers, R. Gosselin, J.-S. Simard and N. Abatzoglou*, In-line near infrared spectroscopy monitoring of pharmaceutical powder moisture in a fluidised bed dryer: An efficient methodology for chemometric model development,Can. J. of Chem. Eng., Vol. 90, Issue 2, April 2012, pp. 299–303.
  • E. Castellanos Gil, R. Gosselin and N. Abatzoglou*, NIRS methodology for measuring radial and axial concentration profiles in flowing granular mixtures,Powder Technology, Vol. 224, 2012, pp. 223-232.
  • J. Salvas, J.-S. Simard, R. Gosselin and N. Abatzoglou*, Calibration of Multivariate Predictive Models: The Study of Factors Influencing the Prediction Accuracy of Raman Spectroscopy Applied to Pharmaceutical Tablets, Amer. Pharm. Rev., Jan-Feb 2011, pp. 36-43.
  • G. Léonard and N. Abatzoglou, Lubrication rates of pharmaceutical powder/wall interfaces and electrostatic effects, Powder Technology, Vol. 208, Issue 1, pp. 54-62, 10 March 2011. (Abstract)
  • N. Abatzoglou and J.-S. Simard, Prediction of segregation tendency in dry particulate pharmaceutical mixtures: Application of an adapted mathematical tool to cohesive and non-cohesive mixtures, Pharmaceutical Development and Technology Vol. 15, Issue 2, 2010, pp. 113-123. (Abstract)
  • G. Léonard and N. Abatzoglou, Stress distribution in lubricated vs unlubricated pharmaceutical powder columns and their container walls during translational and torsional shear testing, Powder Technology, Vol. 203, 2010, pp. 534–547. (Abstract)
  • J. Salvas, J.-S. Simard and N. Abatzoglou, Ph.D., Raman Spectroscopy to Analyze Intact Pharmaceutical Tablets: Factors Influencing MVPM-based PAT Methods,American Pharmaceutical Review, April 2010, pp. 46-53. (Abstract)
  • A. Cournoyer, J.-S. Simard, L. Cartilier, N. Abatzoglou, Quality control of multi-component, intact pharmaceutical tablets with three different near-infrared apparatuses, Pharmaceutical Development & Technology, Vol. 13, Issue 5, September 2008, pp. 333-343. (Abstract)
  • P.-Ph. Lapointe-Garant, J.-S. Simard and N. Abatzoglou, Real-Time NIR Monitoring of a Pharmaceutical Blending Process through Multivariate Analysis-derived Models,Invited Plenary lecture, 1st WSEAS International Conference on Multivariate Analysis and its Application in Science and Engineering (MAASE'08), Istanbul, Turkey, May 27-29, 2008, ISBN: 978-960-6766-68-8. (Abstract)
  • C. Benedetti, J.-S. Simard and N. Abatzoglou, PAT study of a drug manufacturing design space: Effect of blend flow velocity and API level on homogeneity and NIR measurements,Pharmaceutical Engineering, Vol. 28, No 2, March/April 2008, pp. 1-10. (Abstract)
  • C. Benedetti, N. Abatzoglou, J.-S. Simard, L. McDermott, G. Léonard, L. Cartilier, Cohesive, multicomponent, dense powder flow characterization by NIR,International Journal of Pharmaceutics, 336, Issue 2, 2007, pp. 292-301. (Abstract)
  • E. DesRosiers Lachiver, N. Abatzoglou, L. Cartilier, J.-S. Simard, Agglomeration tendency in dry pharmaceutical granular systems, European Journal of Pharmaceutics and Biopharmaceutics, Vol. 64, Issue 2, October 2006, pp. 193-199. (Abstract)
  • P. Côté, N. Abatzoglou, Powder and Other Divided Solids Mixing. Scale-up and Parametric Study of a Ribbon Blender Used in Pharmaceutical Powders Mixing, Pharmaceutical Development and Technology, Vol. 11, No 1, 2006, pp. 29-45. (Abstract)
  • E. DesRosiers Lachiver, N. Abatzoglou, L. Cartilier, and J.-S. Simard, Insights into the Role of Electrostatic Forces on the Behavior of Dry Pharmaceutical Particulate Systems,Pharmaceutical Research, Vol. 23, No. 5, May 2006, pp. 997-1007. (Abstract)
  • N. Abatzoglou, and J.-S. Simard, Prediction of Segregation Tendency Occurrence in Dry Particulate Pharmaceutical Mixtures: Development of a Mathematical Tool Adapted for Granular Systems Application,Pharmaceutical Development and Technology,Vol. 10, No. 1, 2005, pp. 59-70. (Abstract)

Other papers

  • K. Yekpe, N. Abatzoglou*, B. Bataille*, R. Gosselin, Tahmer Sharkawi and J-S. Simard, Turbidity as a PAT tool to measure disintegration profiles of finished solid products, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey, March 19-22, 2012.
  • J.-M. Guay, P.-Ph. Lapointe-Garant, J.-S. Simard* and N. Abatzoglou*, Capabilities and limitations of In-line Multivariate LIF analyzer for powder monitoring, IFPAC-2012, Baltimore, USA, Jan. 22-25, 2012.
  • J. Salvas, J.-S. Simard, R. Gosselin and N. Abatzoglou*, Calibration of Multivariate Predictive Models: The Study of Factors Influencing the Prediction Accuracy of Raman Spectroscopy Applied to Pharmaceutical Tablets, American Pharmaceutical Review, Jan-Feb 2011, pp. 36-43. (Abstract)
  • J. Salvas, J.-S. Simard and N. Abatzoglou, Ph.D., Raman Spectroscopy to Analyze Intact Pharmaceutical Tablets: Factors Influencing MVPM-based PAT Methods, American Pharmaceutical Review, April 2010, pp. 46-53. (Abstract)
  • N. Abatzoglou, Pharmaceutical Industry/University R&D Collaboration on Process Analytical Technologies, invited paper, European Pharmaceutical Review, Issue 2, 2010, pp. 42-45. (Abstract)
  • P.-P. Lapointe-Garant, N. Abatzoglou, J.-S. Simard, Real-time NIR Monitoring of Pharmaceutical Blending Processes with Multivariate Quantitative Models, European Pharmaceutical Review, Vol. 14, Issue 5, 2009, pp. 57-67. (Abstract)